Find hotels near Mcleod Regional Medical Center, Florence from $66
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Our top choices for Mcleod Regional Medical Center hotels

Hyatt Place Florence Downtown
Hyatt Place Florence Downtown0.5 mi from Mcleod Regional Medical Center
8.8 out of 10, Excellent, (1000)
$100 nightly
The price is $112
Jan 5 - Jan 6, 2026
Total with taxes and fees

Hotel Florence, Tapestry Collection by Hilton
Hotel Florence, Tapestry Collection by Hilton0.5 mi from Mcleod Regional Medical Center
8.8 out of 10, Excellent, (602)
$130 nightly
The price is $146
Dec 21 - Dec 22
Total with taxes and fees

Howard Johnson by Wyndham Florence
Howard Johnson by Wyndham Florence3.4 mi from Mcleod Regional Medical Center
8.6 out of 10, Excellent, (2483)
$62 nightly
The price is $70
Dec 14 - Dec 15
Total with taxes and fees

Park Inn by Radisson Florence, SC
Park Inn by Radisson Florence, SC3.4 mi from Mcleod Regional Medical Center
9.0 out of 10, Wonderful, (2197)
$94 nightly
The price is $105
Dec 14 - Dec 15
Total with taxes and fees

Comfort Inn & Suites Florence Center Area
Comfort Inn & Suites Florence Center Area4.3 mi from Mcleod Regional Medical Center
9.2 out of 10, Wonderful, (1161)
$100 nightly
The price is $112
Dec 14 - Dec 15
Total with taxes and fees

Hampton Inn & Suites Florence-North-I-95
Hampton Inn & Suites Florence-North-I-953.6 mi from Mcleod Regional Medical Center
9.0 out of 10, Wonderful, (811)
$106 nightly
The price is $118
Jan 7 - Jan 8, 2026
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Mcleod Regional Medical Center Hotel Reviews

Hampton Inn & Suites Florence-North-I-95
10/10 Excellent
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