$347 Cheap Flights from Panama City (PTY) to Las Vegas (LAS)

View $347 flight on Wed, Dec 17, 2025Opens in a new window

Popular airlines from Tocumen Intl. Airport (PTY) to Harry Reid Intl. Airport (LAS)

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Cheap Flights from Panama City to Las Vegas (PTY-LAS)

Prices were available within the past 7 days and start at $347 for one-way flights and $611 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Wed, Feb 11 - Wed, Feb 25
PTY
Panama City
LAS
Las Vegas
$611 Roundtrip, found 1 hour ago
$611
Roundtrip
found 1 hour ago
Select Copa flight, departing Wed, Feb 11 from Panama City to Las Vegas, returning Wed, Feb 25, priced at $611 found 1 hour ago
Aeromexico
Wed, Dec 24 - Thu, Jan 1
PTY
Panama City
LAS
Las Vegas
$623 Roundtrip, found 8 hours ago
$623
Roundtrip
found 8 hours ago
Select Aeromexico flight, departing Wed, Dec 24 from Panama City to Las Vegas, returning Thu, Jan 1, priced at $623 found 8 hours ago
Delta
Wed, Sep 30 - Sat, Oct 3
PTY
Panama City
LAS
Las Vegas
$625 Roundtrip, found 2 hours ago
$625
Roundtrip
found 2 hours ago
Select Delta flight, departing Wed, Sep 30 from Panama City to Las Vegas, returning Sat, Oct 3, priced at $625 found 2 hours ago
United
Thu, Feb 12 - Wed, Feb 18
PTY
Panama City
LAS
Las Vegas
$625 Roundtrip, found 1 hour ago
$625
Roundtrip
found 1 hour ago
Select United flight, departing Thu, Feb 12 from Panama City to Las Vegas, returning Wed, Feb 18, priced at $625 found 1 hour ago
American Airlines
Wed, Apr 1 - Wed, Apr 8
PTY
Panama City
LAS
Las Vegas
$625 Roundtrip, found 6 hours ago
$625
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Wed, Apr 1 from Panama City to Las Vegas, returning Wed, Apr 8, priced at $625 found 6 hours ago
Copa
Tue, Feb 17 - Thu, Feb 26
PTY
Panama City
LAS
Las Vegas
$627 Roundtrip, found 1 day ago
$627
Roundtrip
found 1 day ago
Select Copa flight, departing Tue, Feb 17 from Panama City to Las Vegas, returning Thu, Feb 26, priced at $627 found 1 day ago
Aeromexico
Tue, Jan 20 - Sat, Jan 24
PTY
Panama City
LAS
Las Vegas
$629 Roundtrip, found 4 days ago
$629
Roundtrip
found 4 days ago
Select Aeromexico flight, departing Tue, Jan 20 from Panama City to Las Vegas, returning Sat, Jan 24, priced at $629 found 4 days ago
American Airlines
Sun, Feb 8 - Sun, Feb 22
PTY
Panama City
LAS
Las Vegas
$635 Roundtrip, found 1 day ago
$635
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sun, Feb 8 from Panama City to Las Vegas, returning Sun, Feb 22, priced at $635 found 1 day ago
United
Thu, Feb 12 - Wed, Feb 18
PTY
Panama City
LAS
Las Vegas
$637 Roundtrip, found 1 hour ago
$637
Roundtrip
found 1 hour ago
Select United flight, departing Thu, Feb 12 from Panama City to Las Vegas, returning Wed, Feb 18, priced at $637 found 1 hour ago
Aeromexico
Tue, Feb 17 - Thu, Feb 26
PTY
Panama City
LAS
Las Vegas
$640 Roundtrip, found 1 day ago
$640
Roundtrip
found 1 day ago
Select Aeromexico flight, departing Tue, Feb 17 from Panama City to Las Vegas, returning Thu, Feb 26, priced at $640 found 1 day ago

Find the cheapest month to fly from Panama City (PTY) to Las Vegas (LAS)

October is typically the cheapest month to fly

From $467 - $858 per traveler.

Alternative airports near Las Vegas

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to McCarran Intl. LAS. Cheapest and Closest option available. Average driving time to city center is 6 minutes. Flights from $798
LAS
McCarran Intl.
CheapestClosest
Average driving time to city center6 min
Flights from $798
Flights from Panama City (PTY) to Las Vegas (LAS)
Origin airport
Tocumen Intl.
Destination airport
Harry Reid Intl.
Airlines serving
Aeromexico, American Airlines, Copa, Delta, United, avianca
Roundtrip price
$610
Distance
2918 mi
Average flight time
7 hours 5 mins

Panama City to Las Vegas Flights

The cheapest times to fly from Panama City to Las Vegas

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Panama City to Las Vegas are during the month of February. You can find some of the cheapest flights from Panama City to Las Vegas with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Panama City to Las Vegas

Sunday is one of the best days to book for cheap flights from Panama City to Las Vegas: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Panama City to Las Vegas

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Panama City to Las Vegas in 2026. You can also book with separate airlines for your outbound and return journeys, from $347 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Panama City to Las Vegas flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Panama City to Las Vegas airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Tocumen Intl. Airport (PTY) to Harry Reid Intl. Airport (LAS) cost?
Lock in a cheap one-way flight from $347 or cheap return flight from $611 from Tocumen Intl. Airport (PTY) to Harry Reid Intl. Airport (LAS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Tocumen Intl. Airport (PTY) to Harry Reid Intl. Airport (LAS)?
Flying in February is a good way to save, as it's the cheapest month for flights between PTY and LAS. You'll often find the lowest prices during the off-season.
Which airlines fly direct from Tocumen Intl. Airport (PTY) to Harry Reid Intl. Airport (LAS)?
When departing from Tocumen Intl. Airport (PTY), you can hop on a direct flight to Harry Reid Intl. Airport (LAS) with Copa Airlines.
What is the cheapest airline that flies from Tocumen Intl. Airport (PTY) to Harry Reid Intl. Airport (LAS)?
To find the cheapest airline that'll fly you from PTY to LAS, use Expedia's filter tool. Tailor your search based on what matters most to you, such as preferred carriers and cabin class. You can then sort your results by "Price (lowest to highest)" to see the most affordable options first.
How many flights per day from Tocumen Intl. Airport (PTY) to Harry Reid Intl. Airport (LAS)?
On average, you can take your pick of 5 nonstop flights taking off from Tocumen Intl. Airport (PTY) to Harry Reid Intl. Airport (LAS) each week. If you can't see one that works for your schedule, consider a flight that includes a layover. Customize your search on Expedia to include one or two stops and opt for the next best alternative.
What are the most popular departure times for flights from Tocumen Intl. Airport (PTY) to Harry Reid Intl. Airport (LAS)?
Flights between PTY and LAS are busiest at 6 PM. For a less crowded experience and potentially cheaper tickets, look for a time outside the usual busy windows.
What day of the week has the most flights from PTY to LAS?
Thursday has the most flights from Tocumen Intl. Airport (PTY) to Harry Reid Intl. Airport (LAS). Consider traveling on this day and you'll have a greater chance of finding a schedule that works for you.
What is the earliest flight from Tocumen Intl. Airport (PTY) to Harry Reid Intl. Airport (LAS)?
Tocumen Intl. Airport (PTY)'s earliest flight to Harry Reid Intl. Airport (LAS) is at approximately 6:28PM UTC-5. With a travel duration of 7h 2m, you'll touch down at around 10:30PM UTC-8.
How long does it take to fly from Tocumen Intl. Airport (PTY) to Harry Reid Intl. Airport (LAS)?
The average flight time from PTY to LAS is 7 hours and 2 minutes, covering a distance of 2,900 mi.
What airline has the least delays from PTY to LAS?
Consider booking with Copa Airlines if you'd like to go straight from Tocumen Intl. Airport (PTY) to Harry Reid Intl. Airport (LAS) without any delays. This airline has the best track record for punctuality, with an on-time score of 94%. Want to get notified of any changes? You can keep an eye on your flight status using the Expedia App.
What is the best time to fly from Tocumen Intl. Airport (PTY) to Harry Reid Intl. Airport (LAS)?
To reach Harry Reid Intl. Airport (LAS) on schedule, book a flight that leaves Tocumen Intl. Airport (PTY) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Las Vegas from Tocumen Intl. Airport (PTY)?
Harry Reid Intl. Airport (LAS) is the only airport in Las Vegas with direct flights from Tocumen Intl. Airport (PTY). Consider the available options and find affordable fares on Expedia.
Is it cheaper to buy a plane ticket from Tocumen Intl. Airport (PTY) to Harry Reid Intl. Airport (LAS) last-minute?
Waiting until right before your break to book a flight from PTY to LAS generally means paying more. While you may find some last-minute offers, they're not always guaranteed. Keep your travel plans flexible to maximize your chances of getting a bargain.
Is it cheaper to book a PTY to LAS flight and hotel package?
You'll generally save money by booking a PTY to LAS flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage it all in one convenient place. Once you've selected your ideal flights and accommodations, consider adding extras such as car rentals, activities and tours.
Can I cancel or change the date of my flight from Tocumen Intl. Airport (PTY) to Harry Reid Intl. Airport (LAS)?
In most cases, you can cancel or modify your PTY to LAS flight. However, there may be additional charges, especially if you made your booking more than 24 hours ago. Double-check your itinerary for the airline's policies and fees on flight changes, or if you need further details, go to our Customer Service portal.

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*Available to One Key members.