$206 Cheap Flights from Tampa (TPA) to Panama City (PTY)

View $206 flight on Thu, Oct 30, 2025Opens in a new window

Popular airlines from Tampa Intl. Airport (TPA) to Tocumen Intl. Airport (PTY)

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Cheap Flights from Tampa to Panama City (TPA-PTY)

Prices were available within the past 7 days and start at $206 for one-way flights and $395 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Fri, Aug 22 - Mon, Aug 25
TPA
Tampa
PTY
Panama City
$395 Roundtrip, just found
$395
Roundtrip
just found
Select Copa flight, departing Fri, Aug 22 from Tampa to Panama City, returning Mon, Aug 25, priced at $395 just found
Copa
Wed, Sep 17 - Sun, Sep 21
TPA
Tampa
PTY
Panama City
$405 Roundtrip, just found
$405
Roundtrip
just found
Select Copa flight, departing Wed, Sep 17 from Tampa to Panama City, returning Sun, Sep 21, priced at $405 just found
Copa
Sun, Nov 2 - Sun, Nov 9
TPA
Tampa
PTY
Panama City
$415 Roundtrip, found 1 hour ago
$415
Roundtrip
found 1 hour ago
Select Copa flight, departing Sun, Nov 2 from Tampa to Panama City, returning Sun, Nov 9, priced at $415 found 1 hour ago
Copa
Wed, Sep 3 - Wed, Sep 10
TPA
Tampa
PTY
Panama City
$443 Roundtrip, just found
$443
Roundtrip
just found
Select Copa flight, departing Wed, Sep 3 from Tampa to Panama City, returning Wed, Sep 10, priced at $443 just found
Copa
Wed, Sep 3 - Sun, Sep 14
TPA
Tampa
PTY
Panama City
$453 Roundtrip, just found
$453
Roundtrip
just found
Select Copa flight, departing Wed, Sep 3 from Tampa to Panama City, returning Sun, Sep 14, priced at $453 just found
American Airlines
Tue, Oct 14 - Mon, Oct 20
TPA
Tampa
PTY
Panama City
$457 Roundtrip, just found
$457
Roundtrip
just found
Select American Airlines flight, departing Tue, Oct 14 from Tampa to Panama City, returning Mon, Oct 20, priced at $457 just found
Delta
Tue, Oct 14 - Mon, Oct 20
TPA
Tampa
PTY
Panama City
$457 Roundtrip, just found
$457
Roundtrip
just found
Select Delta flight, departing Tue, Oct 14 from Tampa to Panama City, returning Mon, Oct 20, priced at $457 just found
United
Tue, Oct 14 - Mon, Oct 20
TPA
Tampa
PTY
Panama City
$457 Roundtrip, just found
$457
Roundtrip
just found
Select United flight, departing Tue, Oct 14 from Tampa to Panama City, returning Mon, Oct 20, priced at $457 just found
American Airlines
Fri, Dec 5 - Wed, Dec 10
TPA
Tampa
PTY
Panama City
$462 Roundtrip, found 7 hours ago
$462
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Fri, Dec 5 from Tampa to Panama City, returning Wed, Dec 10, priced at $462 found 7 hours ago
avianca
Thu, Oct 30 - Sun, Nov 2
TPA
Tampa
PTY
Panama City
$471 Roundtrip, just found
$471
Roundtrip
just found
Select avianca flight, departing Thu, Oct 30 from Tampa to Panama City, returning Sun, Nov 2, priced at $471 just found

Find the cheapest month to fly from Tampa (TPA) to Panama City (PTY)

May is typically the cheapest month to fly

From $254 - $677 per traveler.

Graph displaying average flight prices per month

Alternative airports near Panama City

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Tocumen Intl. PTY. Cheapest option available. Average driving time to city center is 16 minutes. Flights from $443
PTY
Tocumen Intl.
Cheapest
Average driving time to city center16 min
Flights from $443
Flights from Tampa (TPA) to Panama City (PTY)
Origin airport
Tampa Intl.
Destination airport
Tocumen Intl.
Airlines serving
American Airlines, Copa, Delta, United, avianca
Roundtrip price
$394
Distance
1322 mi
Average flight time
2 hours 22 mins

Tampa to Panama City Flights

The cheapest times to fly from Tampa to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Tampa to Panama City are during the month of August. You can find some of the cheapest flights from Tampa to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Tampa to Panama City

Sunday is one of the best days to book for cheap flights from Tampa to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Tampa to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Tampa to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $206 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Tampa to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Tampa to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Tampa Intl. Airport (TPA) to Tocumen Intl. Airport (PTY) cost?
Cheap round-trip fares from Tampa Intl. Airport (TPA) to Tocumen Intl. Airport (PTY) start from $443. This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a Copa flight leaving TPA on August 19 2025 and touching down at PTY. The price was last updated on July 23 2025 and has not changed since.
What is the cheapest month to fly from TPA to PTY?
The cheapest flights from TPA to PTY are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Tampa Intl. Airport (TPA) to Tocumen Intl. Airport (PTY)?
When flying out of Tampa Intl. Airport (TPA), you can hop on a direct flight to Tocumen Intl. Airport (PTY) with Copa Airlines.
What is the cheapest airline that flies from TPA to PTY?
Right now, the cheapest airline offering one-way flights from TPA to PTY is Copa. You can take off on this route from $498. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from TPA on September 26 2025. Prices were last updated on July 23 2025 and have not changed since.
How many flights per day from Tampa Intl. Airport (TPA) to Tocumen Intl. Airport (PTY)?
On average, there's only 1 nonstop flight departing from Tampa Intl. Airport (TPA) to Tocumen Intl. Airport (PTY) every day. If this isn't convenient for you, consider flights with layovers. Just customize your search results on Expedia to include one or two stops to find the next best option.
What are the most popular departure times for flights from Tampa Intl. Airport (TPA) to Tocumen Intl. Airport (PTY)?
The 2 PM departures from TPA to PTY see the highest demand. Prices can be higher for these popular slots. If you want to save on your trip, pick a less crowded time to fly.
What day of the week has the most flights from TPA to PTY?
Jet off on a Friday if you're looking for the best selection of flights from Tampa Intl. Airport (TPA) to Tocumen Intl. Airport (PTY).
What is the earliest flight from Tampa Intl. Airport (TPA) to Tocumen Intl. Airport (PTY)?
Tampa Intl. Airport (TPA)'s first flight to Tocumen Intl. Airport (PTY) takes off at approximately 2:32PM UTC-5. With a travel time of 3h 28m, you'll touch down at around 6:00PM UTC-5.
How long does it take to fly from Tampa Intl. Airport (TPA) to Tocumen Intl. Airport (PTY)?
Flights from TPA to PTY have an average travel time of 3 hours and 28 minutes. The distance between these two airports is 1,300 mi.
What airline has the least delays from TPA to PTY?
Consider traveling with United Airlines if you'd like to go straight from Tampa Intl. Airport (TPA) to Tocumen Intl. Airport (PTY) without any holdups. This airline has the strongest track record for punctuality, with an on-time performance of 100%. Want to be updated if anything changes? You can check your flight status using the Expedia App.
What is the best time to fly from Tampa Intl. Airport (TPA) to Tocumen Intl. Airport (PTY)?
To avoid potential delays on the Tampa Intl. Airport (TPA) to Tocumen Intl. Airport (PTY) route, aim to travel before 3 PM. Departures after this time are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Panama City from Tampa Intl. Airport (TPA)?
If you're flying on a direct flight from Tampa Intl. Airport (TPA) to Panama City, Tocumen Intl. Airport (PTY) is the only airport you can land at.
Is it cheaper to buy a plane ticket from Tampa Intl. Airport (TPA) to Tocumen Intl. Airport (PTY) last-minute?
Holding off until just before your trip to book a ticket from TPA to PTY often results in higher prices. Although you may find some last-minute discounts, there's no guarantee. Be flexible with your itinerary to boost your chances of getting a bargain.
Is it cheaper to book a TPA to PTY flight and hotel package?
Booking a TPA to PTY flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip all in one place. Select from our wide range of accommodations and then add car rentals, flights and activities to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Tampa Intl. Airport (TPA) to Tocumen Intl. Airport (PTY)?
It's generally possible to cancel or reschedule your TPA to PTY flight. However, if it's been more than 24 hours since booking, additional charges may apply. Check your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find more details on our Customer Service portal.

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*Available to One Key members.