$163 Cheap American Airlines flights Manchester (MHT) to Las Vegas (LAS)

Set the "Price (lowest to highest)" filter on Expedia to search for cheap American Airlines return flights from $325 from MHT to LAS. Affordable one-way options from $163 are available too.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Search for affordable American Airlines flights from Manchester-Boston Regional Airport (MHT) to Harry Reid Intl. Airport (LAS) one to three months ahead of your departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. No matter the fare type and journey, the best day of the week to book a domestic flight is generally Sunday and the most expensive day is typically Monday. Passengers who book on a Sunday can save 6% on average compared to those who book their travel on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

To find the earliest departure from MHT to LAS with American Airlines, sort your results by "Morning" and "Early Morning." Booking an early flight usually means cancellations are less likely.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.