$219 Cheap Delta flights Detroit (DTW) to Des Moines (DSM)

Use the "Price (lowest to highest)" filter on Expedia to look for cheap Delta Air Lines return flights from $327 from DTW to DSM. Affordable one-way options from $219 are available too.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Start searching one to three months ahead of your travel date to score cheap fares on Delta Air Lines flights from Detroit Metropolitan Wayne County Airport (DTW) to Des Moines Intl. Airport (DSM). You can save 25% by booking your domestic flight 34 to 86 days in advance versus last-minute reservations made 6 to 12 days out. You could also cut costs by buying your fare on a Sunday, as it's 6% cheaper on average than a Monday, the most expensive day to book.* Get the timing right, and you can enjoy significant savings on domestic flights.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

The first Delta Air Lines flight from DTW to DSM departs at 8:40AM UTC-5, arriving at 9:49AM UTC-6. If you want to jet off later in the day, the last Delta Air Lines flight leaves DTW at 7:55PM UTC-5 and lands at DSM at 8:57PM UTC-6. Flying early is often a smart choice as morning and mid-morning flights are least likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.

Delta Air Lines makes traveling from DTW to DSM enjoyable with an excellent in-flight experience and a rewarding loyalty program. You may even earn points with Delta SkyMiles. Be sure to sign up to Expedia's free One Key™ rewards program to earn OneKeyCash™*, which can be redeemed on future bookings.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.