$126 Cheap Delta flights Knoxville (TYS) to Portland (PDX)

You can find budget-friendly return Delta Air Lines flights from $251 from TYS to PDX by filtering your results from "Price (lowest to highest)" on Expedia. Or search for deals from $126 for a one-way trip.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Start searching one to three months ahead of your departure date to find cheaper fares on Delta Air Lines flights from McGhee Tyson Airport (TYS) to Portland Intl. Airport (PDX). You can save 25% by booking your domestic flight 34 to 86 days in advance versus last-minute reservations made 6 to 12 days out. You could also cut costs by buying your fare on a Sunday, as it's 6% cheaper on average than a Monday, the most expensive day to book.* Time it well, and you can enjoy significant savings on domestic flights.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

To find the earliest departure from TYS to PDX with Delta Air Lines, sort your results by "Early Morning" and "Morning." Booking an early flight generally means you'll experience fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.

Offering an excellent in-flight experience and a rewarding loyalty program, Delta Air Lines is a top choice for many passengers flying from TYS to PDX. Also, if you're a Delta SkyMiles and One Key™ member booking with Expedia, you could earn OneKeyCash™* on eligible flights on top of your airline miles, which can go toward future getaways.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.