$139 Cheap United flights Portland (PDX) to Des Moines (DSM)

Apply the "Price (lowest to highest)" filter on Expedia to search for cheap United Airlines round-trip flights from $277 from PDX to DSM. Affordable one-way tickets from $139 are also on offer.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Start searching one to three months ahead of your travel date to find cheaper fares on United Airlines flights from Portland Intl. Airport (PDX) to Des Moines Intl. Airport (DSM). You can save 25% by booking your domestic flight 34 to 86 days in advance versus last-minute reservations made 6 to 12 days out. You could also reduce costs by buying your fare on a Sunday, as it's 6% cheaper on average than a Monday, the most expensive day to book.* Get the timing right, and you can enjoy significant savings on domestic journeys.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

To find the earliest departure from PDX to DSM with United Airlines, sort your results by "Early Morning" and "Morning." Booking an early flight generally means cancellations are less likely.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.

Journey from PDX to DSM with United Airlines and look forward to a range of benefits including a rewarding loyalty program. When booking through Expedia as a United Mileage Plus and One Key™ member, you may also earn OneKeyCash™* to use on select future travel purchases.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.