$374 Cheap Flights from Fort Wayne (FWA) to Florence (FLO)

View $374 flight on Fri, Jan 23, 2026Opens in a new window

Popular airlines from Fort Wayne Intl. Airport (FWA) to Florence, SC (FLO-Florence Regional)

Cheap Flights from Fort Wayne to Florence (FWA-FLO)

Prices were available within the past 7 days and start at $374 for one-way flights and $475 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Fri, Jan 23 - Mon, Jan 26
FWA
Fort Wayne
FLO
Florence
$475 Roundtrip, found 5 days ago
$475
Roundtrip
found 5 days ago
Select American Airlines flight, departing Fri, Jan 23 from Fort Wayne to Florence, returning Mon, Jan 26, priced at $475 found 5 days ago
American Airlines
Fri, Jan 23 - Mon, Jan 26
FWA
Fort Wayne
FLO
Florence
$480 Roundtrip, found 5 days ago
$480
Roundtrip
found 5 days ago
Select American Airlines flight, departing Fri, Jan 23 from Fort Wayne to Florence, returning Mon, Jan 26, priced at $480 found 5 days ago
American Airlines
Wed, Jan 21 - Wed, Jan 28
FWA
Fort Wayne
FLO
Florence
$491 Roundtrip, found 5 days ago
$491
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Jan 21 from Fort Wayne to Florence, returning Wed, Jan 28, priced at $491 found 5 days ago
American Airlines
Wed, Jan 21 - Tue, Jan 27
FWA
Fort Wayne
FLO
Florence
$496 Roundtrip, found 5 days ago
$496
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Jan 21 from Fort Wayne to Florence, returning Tue, Jan 27, priced at $496 found 5 days ago
American Airlines
Wed, Jan 21 - Mon, Jan 26
FWA
Fort Wayne
FLO
Florence
$518 Roundtrip, found 5 days ago
$518
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Jan 21 from Fort Wayne to Florence, returning Mon, Jan 26, priced at $518 found 5 days ago
American Airlines
Wed, Jan 21 - Thu, Jan 29
FWA
Fort Wayne
FLO
Florence
$523 Roundtrip, found 5 days ago
$523
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Jan 21 from Fort Wayne to Florence, returning Thu, Jan 29, priced at $523 found 5 days ago
American Airlines
Fri, Jan 23 - Wed, Jan 28
FWA
Fort Wayne
FLO
Florence
$525 Roundtrip, found 5 days ago
$525
Roundtrip
found 5 days ago
Select American Airlines flight, departing Fri, Jan 23 from Fort Wayne to Florence, returning Wed, Jan 28, priced at $525 found 5 days ago
American Airlines
Tue, Jan 20 - Wed, Jan 28
FWA
Fort Wayne
FLO
Florence
$526 Roundtrip, found 5 days ago
$526
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Jan 20 from Fort Wayne to Florence, returning Wed, Jan 28, priced at $526 found 5 days ago
American Airlines
Fri, Jan 23 - Tue, Jan 27
FWA
Fort Wayne
FLO
Florence
$530 Roundtrip, found 5 days ago
$530
Roundtrip
found 5 days ago
Select American Airlines flight, departing Fri, Jan 23 from Fort Wayne to Florence, returning Tue, Jan 27, priced at $530 found 5 days ago
American Airlines
Tue, Jan 20 - Tue, Jan 27
FWA
Fort Wayne
FLO
Florence
$531 Roundtrip, found 5 days ago
$531
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Jan 20 from Fort Wayne to Florence, returning Tue, Jan 27, priced at $531 found 5 days ago
American Airlines
Thu, Jan 22 - Mon, Jan 26
FWA
Fort Wayne
FLO
Florence
$545 Roundtrip, found 5 days ago
$545
Roundtrip
found 5 days ago
Select American Airlines flight, departing Thu, Jan 22 from Fort Wayne to Florence, returning Mon, Jan 26, priced at $545 found 5 days ago

Black Friday Sale

Limited-time deals: Save up to 50% on select hotels.
Book now
Flights from Fort Wayne (FWA) to Florence (FLO)
Origin airport
Fort Wayne Intl.
Destination airport
Florence Regional
Roundtrip price
$474
Distance
556 mi

Fort Wayne to Florence Flights

The cheapest times to fly from Fort Wayne to Florence

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Fort Wayne to Florence are during the month of January. You can find some of the cheapest flights from Fort Wayne to Florence with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Fort Wayne to Florence

Sunday is one of the best days to book for cheap flights from Fort Wayne to Florence: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Fort Wayne to Florence

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Fort Wayne to Florence in 2025. You can also book with separate airlines for your outbound and return journeys, from $374 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Fort Wayne to Florence flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Fort Wayne to Florence airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Fort Wayne Intl. Airport (FWA) to Florence Regional Airport (FLO) cost?
Snag a cheap one-way flight from $374 or cheap return flight from $475 from Fort Wayne Intl. Airport (FWA) to Florence Regional Airport (FLO) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Fort Wayne Intl. Airport (FWA) to Florence Regional Airport (FLO)?
The cheapest month to fly from FWA to FLO is January, when there's less demand. Off-peak season is typically when airlines offer better prices between these airports.
What is the cheapest airline that flies from Fort Wayne Intl. Airport (FWA) to Florence Regional Airport (FLO)?
Expedia's filter tool lets you easily compare travel time, airlines and fares all in one place. Choose your preferences, then sort by "Price (lowest to highest)" to find the carrier with the cheapest FWA to FLO flight.
How many flights per day from Fort Wayne Intl. Airport (FWA) to Florence Regional Airport (FLO)?
You'll have to take a flight with a layover if you're traveling from Fort Wayne Intl. Airport (FWA) to Florence Regional Airport (FLO). There are no daily direct flights on this route. However, simply filter your search to include one or two stops to discover an option that works for you.
What day of the week has the most flights from FWA to FLO?
You'll typically find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can vary from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Fort Wayne Intl. Airport (FWA) to Florence Regional Airport (FLO)?
To touch down at Florence Regional Airport (FLO) on schedule, choose a flight that leaves Fort Wayne Intl. Airport (FWA) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Fort Wayne Intl. Airport (FWA) to Florence Regional Airport (FLO) last-minute?
Last-minute fares from FWA to FLO are generally more expensive. To secure the best rates, start searching for flights well ahead of time. That being said, if you're flexible with your travel plans, it's possible to find a cheap ticket right before your trip.
Is it cheaper to book a FWA to FLO flight and hotel package?
Compared with arranging hotels and flights separately, booking a FWA to FLO flight and hotel package with Expedia could lead to significant savings. Better yet, having everything in one convenient place will take the stress out of planning your trip. Just secure your flights and choose from our wide range of hotels, then personalize your trip with other add-ons like tours, car rentals and activities.
Can I cancel or change the date of my flight from Fort Wayne Intl. Airport (FWA) to Florence Regional Airport (FLO)?
If you reserved your FWA to FLO flight within the last 24 hours, you may be able to cancel or modify it without fees. Depending on the airline and the type of fare you purchased, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal if you'd like more information.

Explore a world of travel with Expedia

*Available to One Key members.