Top Hampton County Hotels: 2026 Best Hotels in Hampton County

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A white colonial-style building with columns and a covered porch.

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Our top choices for Hampton County hotels

A spacious lobby with a modern design, featuring a reception desk, comfortable seating, and large windows offering a view of the outdoors.

1. Quality Inn Yemassee - Point South I-95

Yemassee

Claudia

$63 nightly

Nov 15 - Nov 16

Total with taxes and fees

A Hampton Inn by Hilton hotel with a clear entrance, a parking area, and a landscaped front yard.

2. Hampton Inn Yemassee/Point South

Yemassee

Charles

$139 nightly

Dec 6 - Dec 7

Total with taxes and fees

A hotel room with a bed, bedside tables, a large mirror, a bathtub, a sofa, and a television.

3. OYO Hampton South Carolina Hwy 278

Hampton

Allison

$138 nightly

Nov 9 - Nov 10

Total with taxes and fees

A reception area with a piano, a desk, and multiple bar stools.

4. Red Roof Inn Yemassee

Yemassee

DeAngelo

$74 nightly

Nov 8 - Nov 9

Total with taxes and fees

A spacious lobby with a coffee table, sofas, and a television. Large windows offer views of palm trees and a parking lot.

5. Econo Lodge Yemassee

Yemassee

jeff

$47 nightly

Nov 28 - Nov 29

Total with taxes and fees

A hotel room with a large bed, bedside tables, a desk, a chair, a TV, and a door with curtains.

6. Knights Inn Yemassee

Yemassee

James

$48 nightly

Nov 22 - Nov 23

Total with taxes and fees

A hotel room with a large bed, two bedside lamps, a chair, a large window with curtains, and a wall-mounted air conditioner.

7. Palmetto Inn

Estill

JORGE

$75 nightly

Nov 8 - Nov 9

Total with taxes and fees

A modern hotel room with a bed, a desk, a chair, a sofa, and artwork on the walls.

8. Best Western Point South

Yemassee

Bradford

9. Motel 6 Yemassee, SC

Yemassee

KENNETH

A hallway with a wooden floor, a door, a small table with a vase, and a rug.

10. Welcome to the Honey House in beautiful Hampton South Carolina

Hampton

Sharrone E.

A deck with Adirondack chairs and a table, overlooking a house with large windows and a light blue exterior.

11. Outdoor Oasis + Tidal Creek Views: Yemassee Escape

Yemassee

A dining area with wicker chairs, a glass table, and a ceiling fan.

12. Lowcountry Orchard Getaway: 4-bedroom house in lovely Yemassee, SC Sleeps 12

Yemassee

C J.

$308 nightly

Nov 17 - Nov 18

Total with taxes and fees

A hotel room with a large bed, a sitting area with a chair, a wardrobe, a bathroom with a bathtub, and a mirror.

13. 3 Queen Bed | Hampton

Hampton, SC

Anonymous traveler

$200 nightly

Nov 9 - Nov 10

Total with taxes and fees

A modern kitchen with dark cabinets, stainless steel appliances, a granite countertop, and wooden flooring.

14. 3-bedroom house in peaceful Hampton with Central AC-Cool/Heat

Hampton

A hotel room with a large bed, a sitting area with a chair, a wooden wardrobe, a bathroom with a bathtub, and a mirror.

15. King Bed|Smoking|Hampton

Hampton, SC

Anonymous traveler

$149 nightly

Nov 9 - Nov 10

Total with taxes and fees

16. King Bed Non-Smoking

Hampton, SC

Anonymous traveler

$147 nightly

Nov 9 - Nov 10

Total with taxes and fees

17. 1 Suite King Bed Non-Smoking Jacuzzi Tub

Hampton, SC

Anonymous traveler

$229 nightly

Nov 9 - Nov 10

Total with taxes and fees

A kitchen with a central island, wooden cabinets, a washing machine, and a dining area with a sofa and chairs.

18. Margie & Hank's 4BR | Fenced Yard | Pet Friendly

Varnville

19. King Bed Accessible Non-Smoking

Hampton, SC

Anonymous traveler

$149 nightly

Nov 9 - Nov 10

Total with taxes and fees

20. 1 Suite King Bed Smoking Jacuzzi Tub

Hampton, SC

Anonymous traveler

$189 nightly

Nov 9 - Nov 10

Total with taxes and fees

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Compare top hotels in Hampton County

Quality Inn Yemassee - Point South I-95 2.5 star property Yemassee View	Hampton Inn Yemassee/Point South 2.5 star property Yemassee View	OYO Hampton South Carolina Hwy 278 2.0 star property Hampton View	Red Roof Inn Yemassee 2.0 star property Yemassee View	Econo Lodge Yemassee 2.0 star property Yemassee View
7.6 Good 342 reviews	8.8 Excellent 853 reviews	8.2 Very good 149 reviews	7.6 Good 679 reviews	7.0 Good 162 reviews
$63 nightly The price is $71 Nov 15 - Nov 16 Total with taxes and fees	$139 nightly The price is $158 Dec 6 - Dec 7 Total with taxes and fees	$138 nightly The price is $152 Nov 9 - Nov 10 Total with taxes and fees	$74 nightly The price is $84 Nov 8 - Nov 9 Total with taxes and fees	$47 nightly The price is $53 Nov 28 - Nov 29 Total with taxes and fees
Yes, Breakfast included No Pool No Spa Yes, Pet friendly Yes, WiFi included Yes, Parking	Yes, Breakfast included Yes, Pool No Spa Yes, Pet friendly Yes, WiFi included Yes, Parking	No Breakfast included No Pool No Spa No Pet friendly Yes, WiFi included Yes, Parking	Yes, Breakfast included Yes, Pool No Spa Yes, Pet friendly Yes, WiFi included Yes, Parking	No Breakfast included No Pool No Spa Yes, Pet friendly Yes, WiFi included Yes, Parking