Title: Guadalupe, CA Inns from $189 | Expedia.com [Guadalupe Travel Guide](https://expedia.com/Guadalupe.dx6204275)[Hotels in Guadalupe](https://expedia.com/Guadalupe-Hotels.d6204275.Travel-Guide-Hotels)[Vacation Rentals in Guadalupe](https://expedia.com/Guadalupe-Vacation-Rentals.d6204275.Travel-Guide-VacationRentals)[Flights to Guadalupe](https://expedia.com/Cheap-Flights-To-Guadalupe.d6204275.Travel-Guide-Flights)[Car Rentals in Guadalupe](https://expedia.com/Car-Rentals-In-Guadalupe.d6204275.Car-Rental-Guide)[Guadalupe Vacation Packages](https://expedia.com/Guadalupe.d6204275.Destination-Travel-Guides) ![Drying seagrass and kelp on isthmus of sand between Pacific ocean and the Santa Maria river at the Rancho Guadalupe Sand Dunes Preserve on the central coast of California United States](https://images.trvl-media.com/place/6204275/c9247d8f-6401-4e4c-b1ac-8339590a517e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6204275/c9247d8f-6401-4e4c-b1ac-8339590a517e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_bundle_and_save.svg) ### Bundle & Save Get more, spend less whenever you see Bundle & Save deals - ![](https://a.travel-assets.com/travel-assets-manager/pictograms-expedia/light__onekey.svg) ### OneKeyCash Earn OneKeyCash on all your eligible bookings - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_ftc.svg) ### Upfront pricing We are not like the others - we include taxes and fees ## Check prices for these dates Next weekend [Mar 6 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=6204275&startDate=2026-03-06&endDate=2026-03-08&adults=2&lodging=INN&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=6204275&startDate=2026-03-13&endDate=2026-03-15&adults=2&lodging=INN&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=6204275&startDate=2026-03-27&endDate=2026-03-29&adults=2&lodging=INN&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Apr 24 - Apr 26](https://www.expedia.com/Hotel-Search?regionId=6204275&startDate=2026-04-24&endDate=2026-04-26&adults=2&lodging=INN&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Guadalupe inns ![Terrace/patio](https://images.trvl-media.com/lodging/40000000/39520000/39514500/39514495/c2079151.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/40000000/39520000/39514500/39514495/10bd6760.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/40000000/39520000/39514500/39514495/8e543ea2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/40000000/39520000/39514500/39514495/2344a3d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wine Stone Inn [](https://www.expedia.com/San-Luis-Obispo-Hotels-Wine-Stone-Inn.h39514495.Hotel-Information) Santa Maria 9.8/10 Exceptional (617 reviews) "Great stay. Small place, perfect for my husband and I that don’t like getting caught in a crowd. Feels more like a B&B. Very cute, spacious rooms (5 stars)! Staff was very friendly and helpful. Perfect walking distance from the shops and restaurants. The complementary continental breakfast was very limited (no eggs, no toast, no meats). We are very happy with our stay and will be back!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nadieska $163 nightly $189 total Mar 1 - Mar 2 Total with taxes and fees [](https://www.expedia.com/San-Luis-Obispo-Hotels-Wine-Stone-Inn.h39514495.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-13&endDate=2026-03-14®ionId=6204275&adults=2&lodging=INN&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=AA_SPRING_PROMO_6204275) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FGuadalupe-Inns.d6204275-aaInns.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FGuadalupe-Inns.d6204275-aaInns.Travel-Guide-Accommodation) ## Top Guadalupe Hotel Reviews ![Spyglass Inn](https://images.trvl-media.com/lodging/1000000/50000/41300/41235/44c3350f_y.jpg) ### Spyglass Inn 10/10 Excellent "Everything waa amazing!!" [](https://expedia.com/San-Luis-Obispo-Hotels-Spyglass-Inn.h41235.Hotel-Information) ![Best Western Casa Grande Inn](https://images.trvl-media.com/lodging/1000000/30000/23100/23008/e16ece78_y.jpg) ### Best Western Casa Grande Inn 10/10 Excellent "The room was clean and lot of space " [](https://expedia.com/San-Luis-Obispo-Hotels-Best-Western-Casa-Grande-Inn.h23008.Hotel-Information) ![Edgewater Inn And Suites](https://images.trvl-media.com/lodging/1000000/900000/894000/893902/3d1c5694_y.jpg) ### Edgewater Inn And Suites 10/10 Excellent "Had an excellent stay at Edgewater Inn and Suites! The room was very clean and comfortable, and the overall atmosphere was relaxing. The staff was friendly and welcoming, which made the experience even better. The location is perfect—close to the beach and within walking distance to great spots around town. We especially loved the morning views and easy access to everything. Would definitely stay here again!" [](https://expedia.com/San-Luis-Obispo-Hotels-Edgewater-Inn-And-Suites.h893902.Hotel-Information) ![Flying Flags Avila Beach](https://images.trvl-media.com/lodging/75000000/74300000/74299200/74299185/c095b35d_y.jpg) ### Flying Flags Avila Beach 10/10 Excellent "Excellent and great staffs" [](https://expedia.com/Avila-Beach-Hotels-Flying-Flags-Avila-Beach.h74299185.Hotel-Information) ![Pismo Lighthouse Suites](https://images.trvl-media.com/lodging/1000000/20000/11000/10966/791e4270_y.jpg) ### Pismo Lighthouse Suites 10/10 Excellent "Clean and spacious rooms. Ocean Views. Good Staff. " [](https://expedia.com/San-Luis-Obispo-Hotels-Pismo-Lighthouse-Suites.h10966.Hotel-Information) ![Oxford Suites Pismo Beach](https://images.trvl-media.com/lodging/1000000/10000/3100/3089/b427747a_y.jpg) ### Oxford Suites Pismo Beach 10/10 Excellent "Amazing location " [](https://expedia.com/San-Luis-Obispo-Hotels-Oxford-Suites-Pismo-Beach.h3089.Hotel-Information) ![Inn at the Pier Pismo Beach, Curio Collection by Hilton](https://images.trvl-media.com/lodging/19000000/18680000/18676000/18675941/w3838h2559x2y0-97fcea63_y.jpg) ### Inn at the Pier Pismo Beach, Curio Collection by Hilton 10/10 Excellent "Everything was good " [](https://expedia.com/San-Luis-Obispo-Hotels-Inn-At-The-Pier.h18675941.Hotel-Information) ![Historic Santa Maria Inn](https://images.trvl-media.com/lodging/1000000/30000/20400/20393/53eb999c_y.jpg) ### Historic Santa Maria Inn 10/10 Excellent "Just wonderful, Staff courteous very helpful, rooms are very nice and big.pet friendly. I truly recommend Santa maria inn.100%" [](https://expedia.com/Santa-Maria-Hotels-Historic-Santa-Maria-Inn.h20393.Hotel-Information) ![SeaCrest OceanFront Hotel](https://images.trvl-media.com/lodging/2000000/1370000/1365400/1365352/w3000h1999x0y0-15b2e131_y.jpg) ### SeaCrest OceanFront Hotel 10/10 Excellent "The staff was very friendly and welcoming. The room was clean, had a fresh and updated look. The bed was confortable, but the view that we had from our room was what sealed the experience. " [](https://expedia.com/San-Luis-Obispo-Hotels-SeaCrest-OceanFront-Hotel.h1365352.Hotel-Information) ## Find out more about Guadalupe ## Guadalupe Inns information | Number of reviews | 617 | | ----------------- | ------ | | Accommodation | 1 Inns | | Lowest Price | $189 | | Highest Price | $189 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - [Hotels near Guadalupe-Nipomo Dunes ](https://www.expedia.com/Guadalupe-Nipomo-Dunes-Hotels.0-l6207567-0.Travel-Guide-Filter-Hotels) - [Hotels near Guadalupe Station ](https://www.expedia.com/Guadalupe-Station-Hotels.d6195617.Travel-Guide-Hotels) - [B&B in Casmalia ](https://www.expedia.com/Casmalia-Bed-And-Breakfast.d3000426900-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Hotels near Oso Flaco Lake ](https://www.expedia.com/Oso-Flaco-Lake-Hotels.0-l553248621532639570-0.Travel-Guide-Filter-Hotels) - [Casmalia Hotels ](https://www.expedia.com/Casmalia-Hotels.d3000426900.Travel-Guide-Hotels) - [5 Star Hotels in Casmalia ](https://www.expedia.com/5Star-Casmalia-Hotels.s50-0-d3000426900.Travel-Guide-Filter-Hotels) - 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[Pismo Beach Hotels ](https://www.expedia.com/Pismo-Beach-Hotels.d9118.Travel-Guide-Hotels) - [Hotels near Nipomo Native Garden ](https://www.expedia.com/Nipomo-Native-Garden-Hotels.0-l553248634983946078-0.Travel-Guide-Filter-Hotels) - [Santa Maria Hotels ](https://www.expedia.com/Santa-Maria-Hotels.d3224.Travel-Guide-Hotels) - [Condo Rentals in Santa Maria ](https://www.expedia.com/Santa-Maria-Condos.d3224-aaCondos.Travel-Guide-Accommodation) - [Motels in Santa Maria ](https://www.expedia.com/Santa-Maria-Motels.d3224-aaMotels.Travel-Guide-Accommodation) - [B&B in Santa Maria ](https://www.expedia.com/Santa-Maria-Bed-And-Breakfast.d3224-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cabin Rentals in Santa Maria ](https://www.expedia.com/Santa-Maria-Cabins.d3224-aaCabins.Travel-Guide-Accommodation) - [Cottages in Santa Maria ](https://www.expedia.com/Santa-Maria-Cottages.d3224-aaCottages.Travel-Guide-Accommodation) - [Vacation Homes in Santa Maria ](https://www.expedia.com/Santa-Maria-Private-Vacation-Homes.d3224-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Apartments in Santa Maria ](https://www.expedia.com/Santa-Maria-Apartments.d3224-aaApartments.Travel-Guide-Accommodation) - [Inns in Santa Maria ](https://www.expedia.com/Santa-Maria-Inns.d3224-aaInns.Travel-Guide-Accommodation) - [Ranches in Santa Maria ](https://www.expedia.com/Santa-Maria-Ranches.d3224-aaRanches.Travel-Guide-Accommodation) - [Rv Parks in Santa Maria ](https://www.expedia.com/Santa-Maria-RV-Parks.d3224-aaRVParks.Travel-Guide-Accommodation) - [Villas in Santa Maria ](https://www.expedia.com/Santa-Maria-Villas.d3224-aaVillas.Travel-Guide-Accommodation) - [Farmstay in Santa Maria ](https://www.expedia.com/Santa-Maria-Agritourism.d3224-aaAgritourism.Travel-Guide-Accommodation) - [Hotels near Santa Maria Fairpark ](https://www.expedia.com/Santa-Maria-Fairpark-Hotels.0-l553248621558560619-0.Travel-Guide-Filter-Hotels) - [Hotels near Santa Maria Public ](https://www.expedia.com/Santa-Maria-Public-Airport-Hotels.0-aSMX-0.Travel-Guide-Filter-Hotels) - [Flights to Casmalia ](https://www.expedia.com/Cheap-Flights-To-Casmalia.d3000426900.Travel-Guide-Flights) - [Flights from Santa Maria Public ](https://www.expedia.com/lp/airports/smx/flights-from-santa-maria-public-airport) - [Flights from Los Angeles (LAX) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/lax/smx/los-angeles-to-santa-maria) - [Flights from Las Vegas (LAS) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/las/smx/las-vegas-to-santa-maria) - [Flights from Phoenix (PHX) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/phx/smx/phoenix-to-santa-maria) - [Flights from San Diego (SAN) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/san/smx/san-diego-to-santa-maria) - [Flights from San Francisco (SFO) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/sfo/smx/san-francisco-to-santa-maria) - [Flights from Sacramento (SMF) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/smf/smx/sacramento-to-santa-maria) - [Flights from Portland (PDX) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/pdx/smx/portland-to-santa-maria) - [Flights from Seattle (SEA) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/sea/smx/seattle-to-santa-maria) - [Flights from San Jose (SJC) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/sjc/smx/san-jose-to-santa-maria) - [Flights from San Luis Obispo (SBP) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/sbp/smx/san-luis-obispo-to-santa-maria) - [Flights from Denver (DEN) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/den/smx/denver-to-santa-maria) - [Flights from Santa Barbara (SBA) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/sba/smx/santa-barbara-to-santa-maria) - [Flights from Fresno (FAT) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/fat/smx/fresno-to-santa-maria) - [Flights from Bakersfield (BFL) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/bfl/smx/bakersfield-to-santa-maria) - [Flights from Detroit (DTW) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/dtw/smx/detroit-to-santa-maria) - [Flights from Orange County (SNA) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/sna/smx/orange-county-to-santa-maria) - [Flights from Ontario (ONT) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/ont/smx/ontario-to-santa-maria) - [Flights from Oakland (OAK) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/oak/smx/oakland-to-santa-maria) - [Flights from Burbank (BUR) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/bur/smx/burbank-to-santa-maria) - [Flights from Chicago (ORD) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/ord/smx/chicago-to-santa-maria) - [Flights from New York (JFK) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/jfk/smx/new-york-to-santa-maria) - [Flights from Reno (RNO) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/rno/smx/reno-to-santa-maria) - [Flights from Salt Lake City (SLC) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/slc/smx/salt-lake-city-to-santa-maria) - [Flights from Eugene (EUG) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/eug/smx/eugene-to-santa-maria) - [Flights from Dallas (DFW) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/dfw/smx/dallas-to-santa-maria) - [Flights from Houston (HOU) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/hou/smx/houston-to-santa-maria) - [Flights from Long Beach (LGB) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/lgb/smx/long-beach-to-santa-maria) - [Flights from Philadelphia (PHL) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/phl/smx/philadelphia-to-santa-maria) - [Flights from Boise (BOI) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/boi/smx/boise-to-santa-maria) - [Flights from Santa Rosa (STS) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/sts/smx/santa-rosa-to-santa-maria) - [Flights from Orlando (MCO) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/mco/smx/orlando-to-santa-maria) - [Flights from Boston (BOS) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/bos/smx/boston-to-santa-maria) - [Flights from Tampa (TPA) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/tpa/smx/tampa-to-santa-maria) - [Flights from Atlanta (ATL) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/atl/smx/atlanta-to-santa-maria) - [Flights from Austin (AUS) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/aus/smx/austin-to-santa-maria) - [Flights from San Antonio (SAT) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/sat/smx/san-antonio-to-santa-maria) - [Flights from Minneapolis (MSP) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/msp/smx/minneapolis-to-santa-maria) - [Flights from Tucson (TUS) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/tus/smx/tucson-to-santa-maria) - [Flights from Palm Springs (PSP) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/psp/smx/palm-springs-to-santa-maria) - [Flights from El Paso (ELP) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/elp/smx/el-paso-to-santa-maria) - [Flights from Spokane (GEG) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/geg/smx/spokane-to-santa-maria) - [Flights from Raleigh (RDU) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/rdu/smx/raleigh-to-santa-maria) - [Flights from Charlotte (CLT) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/clt/smx/charlotte-to-santa-maria) - [Flights from Stockton (SCK) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/sck/smx/stockton-to-santa-maria) - [Flights from Redding (RDD) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/rdd/smx/redding-to-santa-maria) - [Flights from Washington (DCA) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/dca/smx/washington-to-santa-maria) - [Flights from Colorado Springs (COS) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/cos/smx/colorado-springs-to-santa-maria) - [Flights from Honolulu (HNL) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/hnl/smx/honolulu-to-santa-maria) - [Flights from Medford (MFR) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/mfr/smx/medford-to-santa-maria) - [Flights from Kansas City (MCI) to Santa Maria (SMX) ](https://www.expedia.com/lp/flights/mci/smx/kansas-city-to-santa-maria) - [Guadalupe-Nipomo Dunes ](https://www.expedia.com/Guadalupe-Nipomo-Dunes-Guadalupe.d6207567.Vacation-Attraction) - [Oso Flaco Lake ](https://www.expedia.com/Oso-Flaco-Lake-Oceano.d553248621532639570.Vacation-Attraction) - [Visit Casmalia ](https://www.expedia.com/Casmalia.dx3000426900) - [Sandalwood Spa ](https://www.expedia.com/Sandalwood-Spa-Nipomo.d553248621532639596.Vacation-Attraction) - [Monarch Dunes Golf Club ](https://www.expedia.com/Monarch-Dunes-Golf-Club-Nipomo.d6207579.Vacation-Attraction) - [The Luffa Farm ](https://www.expedia.com/The-Luffa-Farm-Nipomo.d553248621532639598.Vacation-Attraction) - [Nipomo Regional Park ](https://www.expedia.com/Nipomo-Regional-Park-Nipomo.d553248634983945129.Vacation-Attraction) - [Santa Maria Museum of Flight ](https://www.expedia.com/Santa-Maria-Museum-Of-Flight-Santa-Maria.d6207562.Vacation-Attraction) - [Santa Maria Fairpark ](https://www.expedia.com/Santa-Maria-Fairpark-Santa-Maria.d553248621558560619.Vacation-Attraction) - [Car rentals near Guadalupe-Nipomo Dunes ](https://www.expedia.com/Car-Rentals-In-Guadalupe-Nipomo-Dunes.d6207567.Car-Rental-Guide) - [Car rentals near Casmalia ](https://www.expedia.com/Car-Rentals-In-Casmalia.d3000426900.Car-Rental-Guide) - [Car rentals near Monarch Dunes Golf Club ](https://www.expedia.com/Car-Rentals-In-Monarch-Dunes-Golf-Club.d6207579.Car-Rental-Guide) - [Enterprise Rental Cars in Santa Maria Public ](https://www.expedia.com/Enterprise-Car-Rentals-In-Santa-Maria-Public.d6031989-c15.Car-Rental-Guide-Suppliers) - [Car rental Santa Maria Airport (SMX) ](https://www.expedia.com/Car-Rentals-In-Santa-Maria-Public.d6031989.Car-Rental-Guide) - [Avis Rental Cars in Santa Maria Public ](https://www.expedia.com/Avis-Car-Rentals-In-Santa-Maria-Public.d6031989-c41.Car-Rental-Guide-Suppliers) - [Hertz Rental Cars in Santa Maria Public ](https://www.expedia.com/Hertz-Car-Rentals-In-Santa-Maria-Public.d6031989-c40.Car-Rental-Guide-Suppliers) - [Budget Rental Cars in Santa Maria Public ](https://www.expedia.com/Budget-Car-Rentals-In-Santa-Maria-Public.d6031989-c39.Car-Rental-Guide-Suppliers)