Due to coronavirus (COVID-19) travel advisories, some destinations may be unavailable for certain dates. Find out more.
Due to coronavirus (COVID-19) travel advisories, some destinations may be unavailable for certain dates. Find out more.
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search over 1 million properties and 550 airlines worldwide

Members save 10% more on select hotels, cars, activities and vacation rentals. Sign up.

Free cancellation on most hotels. Because flexibility matters.

Mark Twain Cave Guide

If you are looking for Mark Twain Cave travel information, Expedia has you covered. When visiting the Hannibal area, Expedia can provide you with extensive Mark Twain Cave information, as well as great savings on nearby hotels and flights! Let Expedia help inspire your next travel plans!

Leave plenty of time for sightseeing tours - you wouldn't want to miss out on top attractions like this one and many more! And before you go, make sure to read Expedia's sightseeing & tourist guide, filled with all you need to know for the best Mark Twain Cave experience possible. Expedia has more than 640,000 properties to browse but we make it easy with advanced search functionality.


Top Mark Twain Cave Flight + Hotel Deals

Best Lodging Options Near Mark Twain Cave

See all 56 Properties near Mark Twain Cave
Best Western On The River $76
Best Western On The River

Best Western On The River

401 North 3rd Street, Hannibal, MO
     
    2.5 out of 5.0 Stars

    Situated in the historical district, this hotel is steps from Jim's Journey: The Huck Finn Freedom Center, Mark Twain Boyhood Home and Museum, and Big River Train Town. Mark Twain Memorial Lighthouse and Molly Brown Museum and Home are also within 10 minutes.

    Quality Inn & Suites Hannibal $61
    Quality Inn & Suites Hannibal

    Quality Inn & Suites Hannibal

    120 Lindsey Drive, Hannibal, MO
       
      2.5 out of 5.0 Stars

      Located in the heart of Hannibal, this hotel is 1.1 mi (1.7 km) from Hannibal Regional Hospital and within 6 mi (10 km) of Molly Brown Museum and Home and Jim's Journey: The Huck Finn Freedom Center. Mark Twain Boyhood Home and Museum and Big River Train Town are also within 6 mi (10 km).

      Motel 6 Hannibal, MO $46
      Motel 6 Hannibal, MO

      Motel 6 Hannibal, MO

      123 Huckleberry Heights Dr, Hannibal, MO
         
        2.0 out of 5.0 Stars

        Situated in Hannibal, this motel is 2.4 mi (3.9 km) from Sodalis Nature Preserve and 2.7 mi (4.3 km) from Rockcliffe Mansion. Molly Brown Museum and Home and Jim's Journey: The Huck Finn Freedom Center are also within 6 mi (10 km).

        Comfort Inn & Suites - Hannibal $72
        Comfort Inn & Suites - Hannibal

        Comfort Inn & Suites - Hannibal

        4000 Market St, Hannibal, MO
           
          2.5 out of 5.0 Stars

          Located in the heart of Hannibal, this hotel is 2.1 mi (3.5 km) from Sodalis Nature Preserve and 2.8 mi (4.4 km) from Rockcliffe Mansion. Bluff City Theater and Molly Brown Museum and Home are also within 6 mi (10 km).

          Riverside Inn $137
          Riverside Inn

          Riverside Inn

          111 Bird St, Hannibal, MO
             
            2.5 out of 5.0 Stars

            Situated in the historical district, this guesthouse is steps from Mark Twain Boyhood Home and Museum and Big River Train Town. Bluff City Theater and Jim's Journey: The Huck Finn Freedom Center are also within 5 minutes.

            Garth Woodside Mansion Bed and Breakfast $240
            Garth Woodside Mansion Bed and Breakfast

            Garth Woodside Mansion Bed and Breakfast

            11069 New London Gravel Rd, Hannibal, MO
               
              3.5 out of 5.0 Stars

              Situated in Hannibal, this bed & breakfast is 2.8 mi (4.5 km) from Sodalis Nature Preserve and within 6 mi (10 km) of Rockcliffe Mansion and Bluff City Theater. Big River Train Town and Molly Brown Museum and Home are also within 6 mi (10 km).

              Super 8 by Wyndham Hannibal $43
              Super 8 by Wyndham Hannibal

              Super 8 by Wyndham Hannibal

              120 Huckleberry Heights Dr, Hannibal, MO
                 
                2.0 out of 5.0 Stars

                Situated in Hannibal, this motel is within 3 mi (5 km) of Rockcliffe Mansion, Sodalis Nature Preserve, and Molly Brown Museum and Home. Mark Twain Boyhood Home and Museum and Big River Train Town are also within 3 mi (5 km).

                Main Street Bed & Breakfast $125
                Main Street Bed & Breakfast

                Main Street Bed & Breakfast

                Corner of Main and Center, 201 North Main, Hannibal, MO
                   
                  3.5 out of 5.0 Stars

                  Situated in Hannibal, this bed & breakfast is steps from Bluff City Theater, Big River Train Town, and Mark Twain Boyhood Home and Museum. Jim's Journey: The Huck Finn Freedom Center and Mark Twain Memorial Lighthouse are also within 10 minutes.