A dry grassland with a few trees, a red building, and mountains in the background.

Find Resorts & Hotels with Spas in Pickens, SC

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Check availability on Pickens Resorts & Hotels with Spas

Tonight
Oct 8 - Oct 9
Tomorrow
Oct 9 - Oct 10
This weekend
Oct 9 - Oct 11
Next weekend
Oct 16 - Oct 18

Our top choices for Pickens hotels with a spa

A two-story house with a tiled roof, a stone fire pit, and outdoor seating.
A bar with a large window view of mountains and a chandelier.
A reception area with a wooden reception desk, a large abstract painting, and a potted plant.
A swimming pool with lounge chairs and a building with balconies.

1. Hotel Domestique

Hotel Domestique
Travelers Rest
  • Retreat to this mountain hotel with therapeutic massage treatments, sauna, and seasonal outdoor pool for deep relaxation.
$419 nightly
$461 total
Oct 25 - Oct 26
Total with taxes and fees
Hotel Domestique
A spa room with two beds, a mural, and a reception desk.
A modern interior with a stone fireplace, seating areas, and a unique ceiling design.
A modern interior with a stone fireplace, leather sofas, and a wooden ceiling.
A modern interior with a fireplace, plush seating, and a stone accent wall.

2. Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection
Greenville Downtown
  • Escape to a Tudor retreat with a full-service spa and rooftop garden overlooking the scenic river in Greenville.
$401 nightly
$441 total
Oct 11 - Oct 12
Total with taxes and fees
Grand Bohemian Lodge Greenville, Autograph Collection
A hotel room with a bed, a bedside lamp, and a small table with candles.
A lakeside lodge with outdoor seating and string lights.
A spacious dining area with multiple tables and chairs, large windows, and ornate chandeliers.
A stone staircase leading to a house with a stone chimney and a small glass door.

3. Greystone Inn

Greystone Inn
Lake Toxaway
  • Soak in mountain views at this lakeside retreat with couples' spa treatment rooms, yoga classes, and deep-tissue massages.
$381 nightly
$426 total
Nov 8 - Nov 9
Total with taxes and fees
Greystone Inn
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Choose what matters most at spa hotels in Pickens

Pool
Breakfast included
Hot tub
4 stars
5 stars

Find out more about Pickens

Top Pickens attractions for a relaxing vacation

Pickens, South Carolina, offers a tranquil escape for travelers seeking spa hotel experiences nestled in nature. Start your journey at the nearby Table Rock State Park, where scenic hiking trails lead you to breathtaking views and serene landscapes, perfect for unwinding after a day of pampering. Another must-visit is the charming downtown area, where local boutiques and artisanal shops provide a taste of Southern culture, allowing you to explore unique finds. For those interested in golf, the nearby Pickens Country Club offers a delightful course for both beginners and seasoned players, ensuring a fun day in the sun. Don’t miss a visit to the historic Hagood Mill, where you can experience live music and crafts, bringing a sense of local heritage into your relaxing getaway. After a day of exploration, retreat to one of the area's hotels that feature spa services, where attentive staff will cater to your every need, ensuring you feel thoroughly pampered. The perfect blend of outdoor adventure and luxurious relaxation awaits you in Pickens.

Top Pickens Hotel Reviews

Frequently asked questions

Looking for a spa hotel in Pickens?
Soothe the senses with some time in one of our wonderful spa hotels. Check out the natural parks in Pickens - worth a picture or two! Hotels with spas are the perfect way to take a break from your daily routine and add a layer of luxury to your vacation.
What's there to see and do in Pickens?
Experience Pickens and visit Hagood Mill Historic Site, Table Rock State Park, and Table Rock State Park Historic District. If you have a little extra time during your trip, you might want to check out Table Rock and Lake Keowee.
What is a Pickens spa hotel?
Spa hotels in Pickens provide lodging and have an on-site spa offering services such as massages and body treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.

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