Find hotels in Santa Cruz from $16

The best area to stay in Santa Cruz is Equipetrol, an upscale district known for its modern amenities and convenient access.

Equipetrol is Santa Cruz's main commercial and entertainment hub, characterized by modern high-rise buildings, wide avenues, and a concentration of upscale hotels, restaurants, and shops. It's a well-developed area with a polished feel, making it easy to navigate and find quality services. The main thoroughfare is Avenida San Martín, which runs through the heart of the district.

For business travelers, Equipetrol is an excellent choice due to its proximity to corporate offices, convention centers, and major financial institutions. Many hotels in this area offer business facilities and easy access to transportation, ensuring a productive and efficient stay.

Couples looking for a comfortable and convenient experience will also find Equipetrol appealing. The neighborhood offers a wide selection of fine dining options, stylish bars, and boutiques.

Two of the best hotels in Santa Cruz that receive consistently high recommendations from travelers are the Novotel Santa Cruz De La Sierra and the Swissôtel Santa Cruz De La Sierra.

The 5-star Novotel Santa Cruz De La Sierra, with an impressive 9.2 rating, offers a luxurious experience with features such as rainfall showerheads, bathrobes, and premium bedding. Guests often highlight the comfortable pillows and excellent restaurant.

Another highly recommended option is the 4.5-star Swissôtel Santa Cruz De La Sierra, also with a 9.2 rating. This hotel provides air conditioning, bathrobes, and a poolside bar. Guests frequently praise its excellent facilities, good beds, and great location, which is just 0.7 miles from Ventura Mall.

For families traveling to Santa Cruz, the Novotel Santa Cruz De La Sierra and the Camino Real Hotel are excellent choices.

The 5-star Novotel Santa Cruz De La Sierra, with a 9.2 rating, offers a wide range of family-friendly amenities including a children's pool, a playground, and a children's club. Connecting rooms, toys, and games are also available, ensuring a comfortable stay for everyone. Guests often praise the comfortable pillows and excellent restaurant.

Another great option is the 4.5-star Camino Real Hotel, rated 8.8. It features a children's playground and a pool specifically for children. Babysitting services are available on-site, and the hotel also has child-friendly window designs for added safety. This hotel is conveniently located just 0.2 miles from Ventura Mall. Guests frequently highlight the excellent location and the super helpful and kind staff. Find more child-friendly accommodations in Santa Cruz

For the best 5-star hotels in Santa Cruz, consider the Novotel Santa Cruz De La Sierra and the Marriott Santa Cruz de la Sierra Hotel.

The Novotel Santa Cruz De La Sierra, with a 9.2 rating, is a luxurious option featuring an Art Deco design. Guests will appreciate amenities such as rainfall showerheads, bathrobes, and premium bedding for a comfortable stay. The hotel also offers 24-hour room service and a private chef option, and many guests highlight the excellent restaurant.

Another excellent choice is the Marriott Santa Cruz de la Sierra Hotel, which holds a 9.0 rating. This hotel provides spacious suites and executive rooms, some with lounge access, suiting guests seeking enhanced comfort and services. It also offers convenient on-site tennis facilities. The hotel is particularly well-located, being just half a mile from Ventura Mall. Find more luxury hotels in Santa Cruz

For highly-rated spa hotels in Santa Cruz, consider the Hotel Cortez, Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel, Camino Real Hotel, and Marriott Santa Cruz de la Sierra Hotel.

The 3.5-star Hotel Cortez, boasting an impressive 9.2 rating, offers a full-service spa with massage services, a sauna, a steam room, and a hot tub, all accessible for guests. Guests frequently praise the kind staff.

Another excellent option is the 3.5-star Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel, which has a 9.0 rating. Its full-service spa provides a wide range of treatments including manicures and pedicures, body wraps, body scrubs, massages, and hydrotherapy, with daily availability. The hotel also features a steam room, sauna, and hot tub. Guests consistently praise its excellent location and friendly staff.

The 4.5-star Camino Real Hotel, rated 8.8, features a full-service spa with massage treatments, a steam room, and couples treatment rooms. Its excellent location and super helpful and kind staff are frequently highlighted by guests.

Finally, the 5-star Marriott Santa Cruz de la Sierra Hotel, with a 9.0 rating, also offers a full-service spa with massage treatments available daily. Guests often mention the great service provided by the hotel. See all spa hotels in Santa Cruz

For hotels in Santa Cruz offering complimentary breakfast, consider the Hampton by Hilton Santa Cruz/Equipetrol, Bolivia, TRYP by Wyndham Santa Cruz, Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel, Cosmopolitano Hotel Boutique, and Hotel Cortez.

The 4.5-star Hampton by Hilton Santa Cruz/Equipetrol, Bolivia, with an impressive 9.2 rating, provides free buffet breakfast daily. Guests consistently praise the good breakfast and the clean, great rooms. It also offers free self-parking and a 24-hour airport shuttle for added convenience.

The 4-star TRYP by Wyndham Santa Cruz, also rated 9.2, includes a free buffet breakfast each morning. This hotel is located about a mile from the Municipal Library and features comfy beds and a nice pool, according to guests.

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel, a 3.5-star property with a 9.0 rating, offers a free buffet breakfast daily. Guests frequently highlight its excellent location and friendly staff. This hotel also boasts a full-service spa with various treatments and a sauna.

The 3.5-star Cosmopolitano Hotel Boutique, rated 9.2, provides a free full breakfast daily. This hotel is conveniently located near several points of interest, including Plaza 24 de Septiembre and San Lorenzo Cathedral. It also offers free self-parking and a 24-hour airport shuttle.

Finally, the 3.5-star Hotel Cortez, with a 9.2 rating, includes a free buffet breakfast daily. Guests appreciate the kind staff at this hotel, which is situated close to the Municipal Library and Plaza 24 de Septiembre. Find more hotels with free breakfast in Santa Cruz

For pet-friendly hotels in Santa Cruz, consider HOTEL OSHO, Ibis Santa Cruz DE LA Sierra, Hotel LP Equipetrol, and Swissôtel Santa Cruz De La Sierra.

The 3.5-star HOTEL OSHO, with a 9.2 rating, warmly welcomes both dogs and cats, even providing food and water bowls for your companions. Guests also appreciate the complimentary continental breakfast, and the hotel is conveniently located just 1.0 mile from Arenal Park.

The 3-star Ibis Santa Cruz DE LA Sierra, rated 9.6, is another excellent choice for travelers with pets, accommodating both dogs and cats. It is also very close to Arenal Park, at a distance of 0.8 miles.

Hotel LP Equipetrol, a 3.5-star establishment with an 8.2 rating, is a pet-friendly option that welcomes dogs and cats. Guests have frequently praised the helpful staff, and the hotel is located 0.6 miles from Ventura Mall.

The 4.5-star Swissôtel Santa Cruz De La Sierra, boasting a 9.2 rating, is a top-tier pet-friendly hotel that permits both dogs and cats. It also offers a convenient 24-hour airport shuttle. This hotel is located 0.7 miles from Ventura Mall and 1.3 miles from Las Brisas Shopping Center, and guests often highlight the excellent facilities, comfortable beds, good showers, and great location. See more pet-friendly hotels in Santa Cruz

For top boutique hotels in Santa Cruz, consider the Novotel Santa Cruz De La Sierra, Hotel LP Santa Cruz Centro, Terranova Suites, Hotel LP Equipetrol, and TRYP by Wyndham Santa Cruz.

The 5-star Novotel Santa Cruz De La Sierra, with a 9.2 rating, offers complimentary breakfast, including a buffet option, and free WiFi. Guests appreciate the comfortable pillows and excellent restaurant. This hotel also provides a 24-hour airport shuttle.

The 3-star Hotel LP Santa Cruz Centro, rated 8.0, provides free WiFi and complimentary toiletries. It also offers free self-parking and a 24-hour airport shuttle.

Terranova Suites, a 3.5-star hotel with an 8.0 rating, features fully equipped kitchens and free WiFi. Guests will find complimentary toiletries and free self-parking available.

The 3.5-star Hotel LP Equipetrol, rated 8.2, offers a 24-hour airport shuttle and an area shuttle. Free WiFi and complimentary toiletries are also provided. Guests frequently mention the helpful staff.

The 4-star TRYP by Wyndham Santa Cruz, with a 9.2 rating, provides a complimentary buffet breakfast and free WiFi. It also includes free self-parking and a 24-hour airport shuttle. Guests often praise the comfy beds and nice pool. See all boutique hotels in Santa Cruz

For much-loved budget hotels in Santa Cruz, consider the Hotel BY Armonia SCZ, Lido Hotel, Hotel LP Santa Cruz Centro, Equipetrol Suites Apart Hotel, or Hotel Puerta del Rey.

The 3-star Hotel BY Armonia SCZ, with an 8.4 rating, offers free WiFi, free breakfast, and a complimentary airport transfer service available 24 hours a day, making it convenient for travelers. Free cribs and toiletries are also provided.

The 3-star Lido Hotel, rated 9.0, is a highly-rated option that includes free buffet breakfast, free toiletries, and free WiFi. It is conveniently located just 0.3 miles from Plaza 24 de Septiembre, the Municipal Library, and La Recova Artisan Walk, and 0.4 miles from San Lorenzo Cathedral.

Another good choice is the 3-star Hotel LP Santa Cruz Centro, which has an 8.0 rating. This hotel provides free WiFi, free toiletries, and a 24-hour airport shuttle. It is located 0.2 miles from Blacutt Square.

The Equipetrol Suites Apart Hotel, with an 8.6 rating, offers free WiFi, free cooked breakfast, and a 24-hour airport shuttle. Pets are also welcome to stay for free at this hotel.

Finally, the 3-star Hotel Puerta del Rey provides free buffet breakfast, free WiFi, and a 24-hour airport shuttle service. It is located 0.8 miles from Plaza 24 de Septiembre and La Recova Artisan Walk, 0.5 miles from the Municipal Library, and 0.9 miles from San Lorenzo Cathedral. View all budget hotels in Santa Cruz

For a romantic escape in Santa Cruz, consider Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel, or Chairú Eco Hotel.

The 3.5-star Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel, with a 9.0 rating, offers a full-service spa with a hot tub, couples treatment rooms, and a variety of body and facial treatments superb for relaxation together. Guests frequently mention the excellent location and friendly staff.

Another excellent choice for couples is the 3.5-star Chairú Eco Hotel, which boasts an impressive 9.6 rating. This hotel features couples dining options and premium bedding for a comfortable stay. Guests consistently praise the extremely helpful staff. See all romantic hotels in Santa Cruz

When looking for hotels near Ventura Mall in Santa Cruz, the Hampton by Hilton Santa Cruz/Equipetrol, Bolivia, and Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel, are excellent choices.

The 4.5-star Hampton by Hilton Santa Cruz/Equipetrol, Bolivia, with an impressive 9.2 rating, is conveniently located just half a mile from Ventura Mall. This hotel offers complimentary breakfast and free self-parking. Guests frequently praise the clean rooms, friendly and helpful staff, and the great breakfast buffet. For families, the hotel provides free cribs, on-site babysitting, and kids' meals. A 24-hour airport shuttle is also available.

Another good option is the 3.5-star Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel, rated 9.0. It is located 0.7 miles from Ventura Mall. Guests commonly highlight the excellent location and friendly staff. The hotel also provides free breakfast and free cribs, along with a pool and kids' meals, making it suitable for families.

For hotels near Santa Cruz (SRZ-El Trompillo) airport, consider the Hotel LP Santa Cruz Centro or the Cosmopolitano Hotel Boutique.

The 3-star Hotel LP Santa Cruz Centro, with an 8.0 rating, is conveniently located just half a mile from the airport. It offers free WiFi, free toiletries, and complimentary self-parking. The hotel also provides a 24-hour airport shuttle service for easy transfers.

Another excellent option is the 3.5-star Cosmopolitano Hotel Boutique, which boasts an impressive 9.2 rating. This hotel is located just one mile from the airport and offers a 24-hour airport shuttle. Guests can enjoy a complimentary full breakfast and free WiFi, along with useful amenities like connecting rooms and free cribs, making it a good choice for families.

The best time to go to Santa Cruz, Bolivia, is during the dry season, which runs from May to October.

During these months, the weather is more consistently pleasant with lower humidity and less rainfall, making it ideal for exploring the city and its surrounding attractions. Temperatures are generally warm and comfortable during the day, cooling down to a comfortable level in the evenings. This period is great for visitors who want to enjoy outdoor activities without the interruption of heavy rains.

Travelers looking to experience the city's cultural events may also find the dry season appealing, as many local festivals and celebrations are scheduled during this time.

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santa Cruz.

Prices for hotels in Santa Cruz often vary, but you can find a great deal from $16 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.