East Prairie, MO
Travel Guide
Visit East Prairie
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
$94 nightly
The price is $108 total per night from Sep 27 to Sep 28
$108 total
Sep 27 - Sep 28
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,003 reviews)
"Excellent hotel"
Reviewed on Sep 20, 2026
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
$66 nightly
The price is $76 total per night from Sep 27 to Sep 28
$76 total
Sep 27 - Sep 28
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,007 reviews)
"This was a very good value. It has been the best hotel I've stayed at in awhile."
Reviewed on Sep 21, 2026
Best Western Plus Sikeston I-55
120 S Interstate Drive Sikeston MO
$87 nightly
The price is $99 total per night from Sep 27 to Sep 28
$99 total
Sep 27 - Sep 28
Total with taxes and fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.4/10 Very Good! (1,006 reviews)
"Very nice at a reasonable price."
Reviewed on Sep 21, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Duck Hunting, Fishing or Relaxing Family Vacation
Hornbeak TN
Stay at this vacation home in Hornbeak. Enjoy a garden, laundry facilities, and patios. Popular attractions Willow Towhead and Rat Island are located ...
10/10 Exceptional! (246 reviews)
"The house and property were very clean and a great location. We will definitely be back."
Reviewed on Sep 20, 2026
Come and relax at the Refuge at beautiful Reelfoot Lake!
Hornbeak TN
Enjoy free WiFi, laundry facilities, and patios. Popular attractions Willow Towhead and Rat Island are located nearby.
9.4/10 Exceptional! (37 reviews)
"The place was nice, however the air-conditioning was out and the refrigerator did not work. It's early September in the south, no a/c means a miserable experience. After some time and several calls/messages I was able to reach the host. He said there was nothing he could do about it other than a ..."
Reviewed on Sep 7, 2026
3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters
Hornbeak TN
Stay at this vacation home in Hornbeak. Enjoy free WiFi, laundry facilities, and patios. Popular attractions Willow Towhead and Rat Island are located ...
10/10 Exceptional! (11 reviews)
"Great place to stay"
Reviewed on Jul 27, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular East Prairie attractions
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- Visit Sikeston
- Visit Bragg City
- Visit Malden
- Visit Dutchtown
- Visit New Madrid
- Visit Steele
- Visit Poplar Bluff
- Visit Wappapello
- Visit Gideon
- Visit Cape Girardeau
- Visit Risco
- Visit Dexter
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- Visit Kennett
- Visit Hayti
- Visit Portageville
- Visit Qulin
- Visit Jackson
- Charleston Vacations
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- Visit Bernie
- Visit Catron
- Visit Oran
- Visit Marble Hill
- Mississippi River
- Ohio River
- Reelfoot Lake State Park
- Reelfoot Lake
- Ohio River Valley
- Discovery Park of America
- Columbus-Belmont State Park
- Marston Community Center
- Union City Masquerade Theatre
- Central Park
- Fort Defiance State Park
- Graham Park
- New Madrid Historical Museum
- Sikeston Depot Museum
- Hunter-Dawson State Historic Site
- Campbell's Point
