East Prairie, MO
Travel Guide
Visit East Prairie
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
$111 nightly
The price is $128 total per night from Jul 1 to Jul 2
$128 total
Jul 1 - Jul 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,000 reviews)
"This was a wonderful stay for the night while traveling. Thankful for the recommendation from the front desk to eat at Lamberts restaurant 3 minutes down the road. So fun!"
Reviewed on Jun 15, 2026
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
$68 nightly
The price is $78 total per night from Jul 13 to Jul 14
$78 total
Jul 13 - Jul 14
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,000 reviews)
"They cancelled our reservation"
Reviewed on Jun 22, 2026
Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
$104 nightly
The price is $118 total per night from Jul 19 to Jul 20
$118 total
Jul 19 - Jul 20
Total with taxes and fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
9/10 Wonderful! (580 reviews)
"Enjoyed my stay very clean and comfortable"
Reviewed on Jun 23, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Duck Hunting, Fishing or Relaxing Family Vacation
Hornbeak TN
Stay at this vacation home in Hornbeak. Enjoy a garden, laundry facilities, and patios. Popular attractions Willow Towhead and Rat Island are located ...
10/10 Exceptional! (233 reviews)
"Everything was wonderful and very peaceful, fishing was a little off. But we had a great time."
Reviewed on Jun 22, 2026
Buddy's Reel' Em Inn 2 Bd 1 Bath home on Reelfoot Lake. Sleeps 6.
Hornbeak TN
Stay at this vacation home in Hornbeak. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Willow Towhead and Rat Island are located ...
3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters
Hornbeak TN
Stay at this vacation home in Hornbeak. Enjoy free WiFi, laundry facilities, and patios. Popular attractions Willow Towhead and Rat Island are located ...
10/10 Exceptional! (10 reviews)
"Super friendly and easy to communicate with, great view of the water, good place to fish off the dock, plenty of bathrooms, loved the corn hole boards, and solar lights outside."
Reviewed on May 25, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
Big Oak Tree State Park
You can take time to visit Big Oak Tree State Park during your travels to East Prairie. While you're in the area, wander around the parks.
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- Mississippi River
- Ohio River
- Reelfoot Lake
- Reelfoot Lake State Park
- Discovery Park of America
- Ohio River Valley
- Columbus-Belmont State Park
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- Central Park
- Union City Masquerade Theatre
- Fort Defiance State Park
- Marston Community Center
- Campbell's Point
- New Madrid Historical Museum