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Find hotels in Effingham, SC from $44

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Oct 7 - Oct 8
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Oct 8 - Oct 9
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Oct 9 - Oct 11
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Our top choices for Effingham hotels

A spacious lobby with a checkered floor, a reception desk, and a chandelier.
A hotel room with two beds, a desk with a computer, a chair, and a bathroom with a mirror.
A two-story building with a brick facade, a flat roof, and a covered entrance area.
A vending area with snack and drink options, including Pepsi refrigerators and a 'MARKET' display with various products.

1. Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
Florence
United States
HOMERO
$65 nightly
$72 total
Oct 11 - Oct 12
Total with taxes and fees
Howard Johnson by Wyndham Florence
A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.
A modern living room with a grey sofa, a flat-screen TV, geometric wall art, and a bookshelf with decorative items.
A hotel room with a large bed, a desk with a lamp, a chair, a TV, and a window with curtains.
A modern kitchen with a patterned backsplash, wooden cabinets, and stainless steel appliances.

2. Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
Florence
United States
Windia
$89 nightly
$100 total
Oct 11 - Oct 12
Total with taxes and fees
Park Inn by Radisson Florence, SC
A hotel lobby with a reception desk, seating area, and a television screen.
A hotel room with a bed, a sofa, an ottoman, and a lamp.
A Comfort Inn & Suites hotel with a covered entrance, brick facade, and multiple windows.
A hotel room with a sectional sofa, two ottomans, a bed with a green bedspread, and framed pictures on the wall.

3. Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
Florence
United States
Mila
$101 nightly
$113 total
Nov 1 - Nov 2
Total with taxes and fees
Comfort Inn & Suites Florence Center Area
A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.
A modern bar area with a long counter, bar stools, and a variety of bottles and glasses.
A modern bar area with a long counter, multiple bar stools, and a variety of bottles and glasses.
A multi-story hotel with a modern facade, featuring a prominent 'Hyatt Place' sign on the right.

4. Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
Florence
United States
Ivette
$100 nightly
$112 total
Nov 2 - Nov 3
Total with taxes and fees
Hyatt Place Florence Downtown
An outdoor patio area with tables and chairs, a brick wall, and a glass door leading to the interior.
A spacious living room with hardwood flooring, a staircase, and a large window.
A spacious dining area with multiple tables and chairs, wooden flooring, and a modern chandelier.
A spacious lobby with a grand staircase, plush seating, and a modern kitchen area.

5. The Inn at the Crossroads

The Inn at the Crossroads
Lake City
United States
Paige
$126 nightly
$142 total
Nov 8 - Nov 9
Total with taxes and fees
The Inn at the Crossroads
A hotel room with a desk, chair, bed, and a yellow sofa.
A hotel dining area with wooden tables and chairs, a fireplace, and a television.
A swimming pool with lounge chairs and a building with balconies.
A hotel with a green roof, a sign reading 'Quality Inn & Suites by Choice Hotels,' and a landscaped front yard with small trees and shrubs.

6. Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
Florence
Canada
Noémie
$88 nightly
$99 total
Oct 18 - Oct 19
Total with taxes and fees
Quality Inn & Suites Florence Civic Center
A modern lobby with a stone column, a fireplace, and yellow rocking chairs around a central table.
A hotel with a modern design, featuring a prominent sign for the 'Country Inn & Suites by Radisson.'
A hotel room with two beds, a desk with a chair, a television, and a window with curtains.
An outdoor patio with a wooden table and wicker chairs, a barbecue grill, and a swimming pool in the background.

7. Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
Florence
United States
Tienia
$88 nightly
$98 total
Oct 25 - Oct 26
Total with taxes and fees
Spark by Hilton Florence North I-95, SC
A Courtyard by Marriott hotel with a covered entrance, multiple floors, and a parking lot.
A modern bar area with a counter, stools, and tables.
An indoor swimming pool with clear water, surrounded by tiled walls and a wooden floor. There are chairs and a table near the pool, and large windows allow natural light to enter.
A hotel room with a flat-screen TV, a desk with a chair, a sofa, a small table, and a balcony with outdoor seating.

8. Courtyard by Marriott Florence

Courtyard by Marriott Florence
Florence
United States
George
$102 nightly
$114 total
Oct 18 - Oct 19
Total with taxes and fees
Courtyard by Marriott Florence
A restaurant with brick walls, framed awards, and a bar area.
A spacious kitchen with a dining area, a living room with a fireplace, and a cozy seating arrangement.
An outdoor patio area with a brick wall, a covered seating area with string lights, and potted plants.
A bar area with a curved counter, multiple stools, and a brick wall backdrop.

9. Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
Florence
United States
Ankh
$120 nightly
$135 total
Nov 1 - Nov 2
Total with taxes and fees
Hotel Florence, Tapestry Collection by Hilton
A hotel entrance with a stone facade, glass doors, and a number '501' above.
A corner market with shelves stocked with snacks and beverages, and two large refrigerators.
An indoor swimming pool with a tiled floor, a pool ladder, and lounge chairs.
A modern living room with a stone fireplace, a blue sofa, a brown leather chair, and a round coffee table.

10. Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
Florence
United States
Alma
$118 nightly
$132 total
Oct 11 - Oct 12
Total with taxes and fees
Fairfield Inn & Suites by Marriott Florence I-20
A hotel room with two beds, a wooden headboard, a window with curtains, and a wall-mounted air conditioner.
A modern kitchen with a built-in coffee station, a refrigerator, and a seating area with a patterned rug.
Property amenity
A spacious lobby with a reception desk, a large window display, and a 'market' sign on the wall.

11. SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence
Florence
United States
John
$98 nightly
$110 total
Oct 18 - Oct 19
Total with taxes and fees
SpringHill Suites by Marriott Florence
A modern kitchen with dark wooden cabinets, a stainless steel refrigerator, a microwave, and a coffee maker. There is a dining area with two red chairs and a table.
A conference room with round tables, chairs, and a carpeted floor.
An outdoor kitchen area with a grill, a pool, and a covered seating area.
A hotel room with a bed, a desk, a TV, a refrigerator, and a painting on the wall.

12. Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
Florence
United States
Tishia
$135 nightly
$151 total
Oct 25 - Oct 26
Total with taxes and fees
Staybridge Suites Florence - Civic Center by IHG
A hotel room with a large bed, a desk with a chair, a television, and a walk-in closet.
A hotel pool area with two pools, a lifeguard stand, and a towel service station.
A breakfast setup with a flat-screen TV displaying a breakfast menu, a flat-screen TV, a coffee machine, and a tray of pancakes.
A reception area with a modern design, featuring a reception desk, a digital display, and a sign for Holiday Inn Express & Suites.

13. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Florence
United States
Leigh
$114 nightly
$128 total
Oct 11 - Oct 12
Total with taxes and fees
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
A building with two red doors, one labeled 'Office' and the other '101'. There is a welcome sign and a mailbox on the wall.
A room with a sofa, a small table, a chair, a lamp, and a door.
A house with a stone-paved entrance, a bench, and two red doors labeled "OFFICE" and "PRIVATE."
A compact living space with a dining area, kitchenette, and seating area.

14. Affordable Suites Florence

Affordable Suites Florence
Florence
United States
Cheyenne
$100 nightly
$112 total
Oct 19 - Oct 20
Total with taxes and fees
Affordable Suites Florence
A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.
A modern lounge area with a sofa, armchairs, and small tables.
A self-service beverage station with refrigerated and non-refrigerated drink options, snack shelves, and a sign indicating the location.
A reception area with a wooden desk, a map on the wall, and a sign welcoming visitors to Florence, SC.

15. TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
Florence
United States
Crystal
$114 nightly
$128 total
Nov 1 - Nov 2
Total with taxes and fees
TownePlace Suites by Marriott Florence
An outdoor seating area with a fire pit, cushioned seating, and a pergola with string lights.
A modern hotel with a prominent 'TRU by Hilton' sign, a well-lit entrance, and a landscaped front yard.
A modern hotel restaurant with a breakfast bar, seating area, and a view of the city.
A modern lounge area with seating, tables, and a pool table.

16. Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
Florence
United States
Tiffany
$106 nightly
$119 total
Oct 14 - Oct 15
Total with taxes and fees
Tru by Hilton Florence I-95
A spacious lobby with a high ceiling, a central seating area, and a staircase leading to an upper level.
A hotel room with a bed, sofa, TV, and a desk.
A La Quinta Inn & Suites hotel with a modern facade, a well-lit entrance, and a landscaped garden area.
A hotel room with a bed, a sofa, a desk, and a TV.

17. La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence
Florence
United States
Heather
$86 nightly
$96 total
Oct 11 - Oct 12
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Florence
A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.
A hotel room with two beds, a desk, a TV, and a window with patterned curtains.
A lobby with a fireplace, seating area, and a television.
A hotel lobby with a reception desk, seating area, and a welcome mat.

18. Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
Florence
United States
Ryan
$114 nightly
$128 total
Oct 18 - Oct 19
Total with taxes and fees
Hampton Inn & Suites Florence Center
A hotel room with a large bed, a TV on a wooden stand, a desk, and a chair.
A lobby with leather sofas, a coffee table, potted plants, and a reception desk.
A corridor with shelves stocked with snacks and a frozen food display.
An indoor swimming pool with clear water, surrounded by a checkered wall pattern, and equipped with multiple seating areas and a lifeguard station.

19. Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
Florence
United States
Ashokraju
$122 nightly
$137 total
Oct 14 - Oct 15
Total with taxes and fees
Hampton Inn & Suites Florence-North-I-95
A hotel room with two beds, a desk with a TV, and a bathroom visible through an open door.
A large, two-story building with a central entrance flanked by columns, labeled "DIR FRANK B. LEE NURSING BUILDING."
A coffee station with two coffee machines, a coffee press, and various coffee-related items on a wooden counter.
An outdoor patio area with brick walls, a fire pit, and outdoor seating.

20. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
Florence
United States
Christopher
$131 nightly
$147 total
Oct 11 - Oct 12
Total with taxes and fees
Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
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Top Effingham Hotel Reviews

Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

10/10 Excellent
"Spark always has clean hotels and comfortable beds, this location was no different. Enjoyed our stay"
Kelly 1-night trip
Posted 10 hours ago
Spark by Hilton Florence North I-95, SC
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

10/10 Excellent
"The room was very clean the beds were very comfortable no real complaints. Only problem the toilet seat was Wiggly and my poor husband almost slid across the bathroom lol. That's just a simple fix all else was great and the price was certainly right!"
Peter 1-night trip
Posted 14 hours ago
Quality Inn & Suites Florence Civic Center
The Inn at the Crossroads

The Inn at the Crossroads

10/10 Excellent
"Nice place!!"
Shawn 1-night trip
Posted 1 day ago
The Inn at the Crossroads
Comfort Suites Florence I-95

Comfort Suites Florence I-95

10/10 Excellent
"Excellent!!"
Monique J. 2-night trip
Posted 2 days ago
Comfort Suites Florence I-95
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

10/10 Excellent
"It was ok"
Bill 1-night trip
Posted 2 days ago
Comfort Inn & Suites Florence Center Area
Super 8 by Wyndham Florence

Super 8 by Wyndham Florence

10/10 Excellent
"Excelente lugar"
Edgar 3-night trip
Posted 2 days ago
Super 8 by Wyndham Florence
Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

10/10 Excellent
"Room clean. Staff was courteous and professional. Great location."
Ellen 1-night trip
Posted 6 days ago
Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

More cheap stays in Effingham

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2038 W Lucas Street Florence SC
$65 nightly
$72 total
Oct 11 - Oct 12
Total with taxes and fees
Howard Johnson by Wyndham Florence
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

140 Dunbarton Dr Florence SC
$65 nightly
$73 total
Oct 15 - Oct 16
Total with taxes and fees
Days Inn by Wyndham Florence Near Civic Center
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

150 Dunbarton Dr Florence SC
$88 nightly
$99 total
Oct 18 - Oct 19
Total with taxes and fees
8.4/10 Very Good! (384 reviews)
Quality Inn & Suites Florence Civic Center
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

1729 Mandeville Road Florence SC
$89 nightly
$100 total
Oct 11 - Oct 12
Total with taxes and fees
Park Inn by Radisson Florence, SC
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

527 Woody Jones Blvd Florence SC
$101 nightly
$113 total
Nov 1 - Nov 2
Total with taxes and fees
9/10 Wonderful! (1,372 reviews)
Comfort Inn & Suites Florence Center Area
The Inn at the Crossroads

The Inn at the Crossroads

128 West Main Street Lake City SC
$126 nightly
$142 total
Nov 8 - Nov 9
Total with taxes and fees
9.4/10 Exceptional! (997 reviews)
The Inn at the Crossroads

Hotels in Effingham with star-rating

Frequently asked questions

What is the best area to stay in Effingham?
The best area to stay in Effingham is near the intersection of US-301 and I-95, as this offers the most convenient access to amenities and onward travel.This area is primarily characterized by its array of hotels, restaurants, and gas stations, strategically located for travelers passing through or needing a stopover. You'll find most services concentrated along US-301, just off the I-95 exits. While not a tourist destination in itself, it provides all the necessary conveniences for a comfortable stay.For solo travelers or couples on a road trip, this location is ideal. It offers quick access to the interstate, making it easy to continue your journey. The concentration of dining options, from casual eateries to sit-down restaurants, provides variety without requiring extensive travel.
When is the best time to go to Effingham?
The best time to visit Effingham, South Carolina, is during the spring (March to May) and fall (September to November) months.These seasons offer pleasant weather with mild temperatures, ideal for enjoying outdoor activities without the intense heat and humidity of summer or the cooler, sometimes unpredictable, temperatures of winter. Spring brings blooming flora, while fall showcases colorful foliage, making for scenic drives and comfortable exploration of the local area.For travelers who prefer warm weather and don't mind higher humidity, the summer months (June to August) are also an option. During this time, the days are long, allowing for extended outdoor enjoyment, though afternoon thunderstorms can occur.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Effingham.
How much is the nightly rate at a Effingham hotel?
Prices for hotels in Effingham often vary, but you can find a great deal from $44 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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