Title: Best Depew, NY Lodge Rentals from $63 | Expedia.com [Depew Travel Guide](https://expedia.com/Depew.dx6338362)[Hotels in Depew](https://expedia.com/Depew-Hotels.d6338362.Travel-Guide-Hotels)[Vacation Rentals in Depew](https://expedia.com/Depew-Vacation-Rentals.d6338362.Travel-Guide-VacationRentals)[Flights to Depew](https://expedia.com/Cheap-Flights-To-Depew.d6338362.Travel-Guide-Flights)[Things to do in Depew](https://expedia.com/Things-To-Do-In-Depew.d6338362.Travel-Guide-Activities)[Car Rentals in Depew](https://expedia.com/Car-Rentals-In-Depew.d6338362.Car-Rental-Guide)[Depew Vacation Packages](https://expedia.com/Depew.d6338362.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_bundle_and_save.svg) ### Bundle & Save Get more, spend less whenever you see Bundle & Save deals - ![](https://a.travel-assets.com/travel-assets-manager/pictograms-expedia/light__onekey.svg) ### OneKeyCash Earn OneKeyCash on all your eligible bookings - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_ftc.svg) ### Upfront pricing We are not like the others - we include taxes and fees ## Check prices for these dates Next weekend [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=6338362&startDate=2026-04-03&endDate=2026-04-05&adults=2&lodging=LODGE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=6338362&startDate=2026-04-10&endDate=2026-04-12&adults=2&lodging=LODGE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Apr 24 - Apr 26](https://www.expedia.com/Hotel-Search?regionId=6338362&startDate=2026-04-24&endDate=2026-04-26&adults=2&lodging=LODGE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [May 22 - May 24](https://www.expedia.com/Hotel-Search?regionId=6338362&startDate=2026-05-22&endDate=2026-05-24&adults=2&lodging=LODGE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) No exact matches found, but these alternatives could be just right ## Recommended hotels in Depew ![Interior](https://images.trvl-media.com/lodging/128000000/127200000/127194500/127194430/a07a74c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/128000000/127200000/127194500/127194430/6af93d88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/128000000/127200000/127194500/127194430/eb4c180e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/128000000/127200000/127194500/127194430/015dbfc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 3-bedroom house in close to the airport Buffalo family- friendly no pets allowed [](https://www.expedia.com/Buffalo-Hotels-3-Bedroom-House-In-Close-To-The-Airport-Buffalo-Family-Friendly-No-Pets-Allowed.h127194430.Hotel-Information) Depew $239 nightly $267 total Mar 24 - Mar 25 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-3-Bedroom-House-In-Close-To-The-Airport-Buffalo-Family-Friendly-No-Pets-Allowed.h127194430.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567279/3274a349.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567279/2685a465.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567279/ea0d463b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed | Premium bedding, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567279/a305e7d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Grand Island - Niagara Falls by IHG [](https://www.expedia.com/Niagara-Falls-Hotels-Holiday-Inn-Express-Grand-Island-Niagara-Falls.h18567279.Hotel-Information) Grand Island 9.0/10 Wonderful (1,728 reviews) "Large rooms, great breakfast, very friendly staff, location was great " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Diane $93 nightly $106 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Niagara-Falls-Hotels-Holiday-Inn-Express-Grand-Island-Niagara-Falls.h18567279.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/10000/5200/5183/46db5598.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Accessible, Refrigerator | Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/5200/5183/285a6583.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5200/5183/c135a4a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/5200/5183/73648063.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Summit Inn [](https://www.expedia.com/Niagara-Falls-Hotels-Best-Western-Summit-Inn.h5183.Hotel-Information) Niagara Falls 8.6/10 Excellent (1,446 reviews) "The hotel was a great value - very clean and well kept. The staff were friendly and helpful. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elaine $72 nightly $82 total Mar 24 - Mar 25 Total with taxes and fees [](https://www.expedia.com/Niagara-Falls-Hotels-Best-Western-Summit-Inn.h5183.Hotel-Information) ![Garden](https://images.trvl-media.com/lodging/8000000/7910000/7900500/7900412/1a361d5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/8000000/7910000/7900500/7900412/c3686c83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Double Beds, Kitchen | Premium bedding, pillowtop beds, individually decorated](https://images.trvl-media.com/lodging/8000000/7910000/7900500/7900412/6cd5997e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/8000000/7910000/7900500/7900412/e8b3cf14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clarence Inn [](https://www.expedia.com/Buffalo-Hotels-Clarence-Inn.h7900412.Hotel-Information) Clarence 8.2/10 Very Good (297 reviews) "Great service quiet place and friendly people." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Larry $99 nightly $111 total Mar 24 - Mar 25 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Clarence-Inn.h7900412.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/970000/968200/968172/2e04419a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/970000/968200/968172/8fe475d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/970000/968200/968172/e8dba90d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed with Sofa bed, Non Smoking (King Study) | Hypo-allergenic bedding, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/970000/968200/968172/104f9b47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn East Aurora [](https://www.expedia.com/East-Aurora-Hotels-Hampton-Inn-East-Aurora.h968172.Hotel-Information) East Aurora 9.4/10 Exceptional (1,001 reviews) "Incredibly friendly staff at check in. Room was beautiful and very clean. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Linda $130 nightly $148 total Apr 2 - Apr 3 Total with taxes and fees [](https://www.expedia.com/East-Aurora-Hotels-Hampton-Inn-East-Aurora.h968172.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/100000000/99810000/99802700/99802648/b3c0a8a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking (with Sofabed) | Individually furnished, desk, laptop workspace, free WiFi](https://images.trvl-media.com/lodging/100000000/99810000/99802700/99802648/1eafede6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/100000000/99810000/99802700/99802648/dec807b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/100000000/99810000/99802700/99802648/7d3bff92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Buffalo Inn & Suites [](https://www.expedia.com/Eva-Hotel.h99802648.Hotel-Information) Buffalo 8.8/10 Excellent (899 reviews) "Great stay staff and property we love it " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Ezio $100 nightly $114 total Mar 30 - Mar 31 Total with taxes and fees [](https://www.expedia.com/Eva-Hotel.h99802648.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/10000000/9750000/9743100/9743017/27ee7ea2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/10000000/9750000/9743100/9743017/a36a3e4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/10000000/9750000/9743100/9743017/ed49d5cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Non Smoking (Whirlpool Tub) | In-room safe, desk, laptop workspace, soundproofing](https://images.trvl-media.com/lodging/10000000/9750000/9743100/9743017/9bd79013.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Salvatores Grand Hotel [](https://www.expedia.com/Buffalo-Hotels-Salvatores-Grand-Hotel.h9743017.Hotel-Information) Buffalo 9.6/10 Exceptional (1,003 reviews) "Beautiful hotel , excellent food, worth every penny. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrea $129 nightly $147 total Mar 24 - Mar 25 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Salvatores-Grand-Hotel.h9743017.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/94000000/93470000/93463700/93463671/c4fa613a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/94000000/93470000/93463700/93463671/c8535cdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/94000000/93470000/93463700/93463671/b2b973f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/94000000/93470000/93463700/93463671/2293699f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 420 Friendly 3 bedroom upstairs apartment. Street parking only. [](https://www.expedia.com/Buffalo-Hotels-420-Friendly-3-Bedroom-Upstairs-Apartment-Street-Parking-Only.h93463671.Hotel-Information) Seneca 9.4/10 Exceptional (68 reviews) "Excellent stay! All the things we needed and then some :) highly recommend! Will be staying here anytime I am in the area!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kerry G. $179 nightly $182 total Apr 19 - Apr 20 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-420-Friendly-3-Bedroom-Upstairs-Apartment-Street-Parking-Only.h93463671.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/8000000/7520000/7511900/7511809/2864591b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/8000000/7520000/7511900/7511809/7ff31af2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/8000000/7520000/7511900/7511809/18b78331.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Suite, 1 Bedroom | Premium bedding, pillowtop beds, individually furnished, desk](https://images.trvl-media.com/lodging/8000000/7520000/7511900/7511809/1c0281cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Roycroft Inn [](https://www.expedia.com/East-Aurora-Hotels-Roycroft-Inn.h7511809.Hotel-Information) East Aurora 9.6/10 Exceptional (864 reviews) "Beautiful & historic inn with a wonderful staff & restaurant. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen $149 nightly $166 total Apr 16 - Apr 17 Total with taxes and fees [](https://www.expedia.com/East-Aurora-Hotels-Roycroft-Inn.h7511809.Hotel-Information) ![Standard Studio Suite, 1 King Bed, Jetted Tub | In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/8000000/7670000/7663400/7663327/18b8438d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/8000000/7670000/7663400/7663327/33324e75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/8000000/7670000/7663400/7663327/8334e598.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/8000000/7670000/7663400/7663327/f038d62d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lockport Inn & Suites [](https://www.expedia.com/Niagara-Falls-Hotels-Lockport-Inn-Suites.h7663327.Hotel-Information) Lockport 9.2/10 Wonderful (1,000 reviews) "Very nice family-run cozy stay." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Leonardo $99 nightly $112 total Mar 24 - Mar 25 Total with taxes and fees [](https://www.expedia.com/Niagara-Falls-Hotels-Lockport-Inn-Suites.h7663327.Hotel-Information) ![Standard Room, 1 King Bed, Non Smoking (Ground Floor, Pets Allowed) | 1 bedroom, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/2100/2071/fc11b7d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/2100/2071/19db4ac2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/10000/2100/2071/0cf000f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/2100/2071/a26a08df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Darien Lakes [](https://www.expedia.com/Corfu-Hotels-Econo-Lodge-Darien-Lakes.h2071.Hotel-Information) Corfu 7.8/10 Good (813 reviews) "Staff were prompt with check-in and very direct. It was helpful. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anna $68 nightly $75 total Mar 30 - Mar 31 Total with taxes and fees [](https://www.expedia.com/Corfu-Hotels-Econo-Lodge-Darien-Lakes.h2071.Hotel-Information) ![Deluxe Room, 2 Queen Beds, Non Smoking | Desk, iron/ironing board, free cribs/infant beds, rollaway beds](https://images.trvl-media.com/lodging/2000000/1500000/1497100/1497090/00561ac2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, Non Smoking (2 King Beds) | Desk, iron/ironing board, free cribs/infant beds, rollaway beds](https://images.trvl-media.com/lodging/2000000/1500000/1497100/1497090/ff5fa686.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1500000/1497100/1497090/74836d03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1500000/1497100/1497090/af522590.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn & Suites by Wyndham Niagara Falls/Buffalo [](https://www.expedia.com/Niagara-Falls-Hotels-Days-Inn-Suites-By-Wyndham-Niagara-Fallsbuffalo.h1497090.Hotel-Information) Niagara Falls 8.0/10 Very Good (1,003 reviews) "Wonderful stay will stay again" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) christine $68 nightly $77 total Mar 31 - Apr 1 Total with taxes and fees [](https://www.expedia.com/Niagara-Falls-Hotels-Days-Inn-Suites-By-Wyndham-Niagara-Fallsbuffalo.h1497090.Hotel-Information) ![Fireplace](https://images.trvl-media.com/lodging/74000000/73420000/73412100/73412050/b95ee62f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![The Madison Suite | Bathroom | Shower, hair dryer, towels, soap](https://images.trvl-media.com/lodging/74000000/73420000/73412100/73412050/039a8e7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/74000000/73420000/73412100/73412050/6a75ba52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/74000000/73420000/73412100/73412050/0680ddcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Edward Hotel [](https://www.expedia.com/Buffalo-Hotels-The-Edward-Hotel.h73412050.Hotel-Information) Elmwood Village 9.6/10 Exceptional (227 reviews) "The Edward is quaint and in walking distance to many restaurants and shops. We had a wonderful stay. It’s very clean and all of the rooms are unique in their design which added to the pleasure of our stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shannon $134 nightly $154 total Mar 24 - Mar 25 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-The-Edward-Hotel.h73412050.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/560000/558600/558591/139ee991.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business center](https://images.trvl-media.com/lodging/1000000/560000/558600/558591/295249d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 6:30 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/560000/558600/558591/b33f35a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking | Premium bedding, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/560000/558600/558591/2a472ad1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Near Walden Galleria Mall [](https://www.expedia.com/Buffalo-Hotels-Quality-Inn-Near-Walden-Galleria-Mall.h558591.Hotel-Information) Buffalo 8.0/10 Very Good (1,006 reviews) "Good location for our visit for a concert at Keybank. Room was clean, bed was comfortable." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Melissa $84 nightly $96 total Apr 2 - Apr 3 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Quality-Inn-Near-Walden-Galleria-Mall.h558591.Hotel-Information) ![Suite, 1 King Bed with Sofa bed, Non Smoking | Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/90000/85100/85007/9d03cce3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/90000/85100/85007/77375700.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/90000/85100/85007/d35175de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/85100/85007/ae021a7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn & Suites Buffalo Airport [](https://www.expedia.com/Buffalo-Hotels-Sleep-Inn-Suites-Buffalo-Airport.h85007.Hotel-Information) Buffalo 8.0/10 Very Good (2,017 reviews) "Nice hotel" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Nilanjan $76 nightly $86 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Sleep-Inn-Suites-Buffalo-Airport.h85007.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/48000000/47030000/47021400/47021354/09462364.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/48000000/47030000/47021400/47021354/5de7a4e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/48000000/47030000/47021400/47021354/eaaa575c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/48000000/47030000/47021400/47021354/7ab4a0dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Amherst - Lockport by IHG [](https://www.expedia.com/Buffalo-Hotels-Holiday-Inn-Express-Lockport.h47021354.Hotel-Information) Lockport 9.2/10 Wonderful (765 reviews) "Clean and comfortable accommodations, friendly staff and a great breakfast spread!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrea $111 nightly $125 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Holiday-Inn-Express-Lockport.h47021354.Hotel-Information) ![Deluxe Room, 2 Double Beds (Smoke Free) | 1 bedroom, desk, blackout drapes, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/900/816/dec8cb3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/900/816/6d5f06be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/900/816/b68133b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, blackout drapes, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/900/816/d1c4663a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Buffalo - Niagara Airport [](https://www.expedia.com/Buffalo-Hotels-Red-Roof-Inn-Buffalo-Niagara-Airport.h816.Hotel-Information) Bowmansville 7.2/10 Good (1,001 reviews) "Parking was easy. Room was clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gary $60 nightly $69 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Red-Roof-Inn-Buffalo-Niagara-Airport.h816.Hotel-Information) ![Lunch and dinner served, American cuisine](https://images.trvl-media.com/lodging/1000000/30000/26100/26001/19bd0f50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business center](https://images.trvl-media.com/lodging/1000000/30000/26100/26001/7585a4c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed with Sofa bed | In-room safe, desk, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/26100/26001/52bfdeb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26100/26001/e6ba9cfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Buffalo Airport Hotel [](https://www.expedia.com/Buffalo-Hotels-Buffalo-Airport-Hotel.h26001.Hotel-Information) Buffalo 8.0/10 Very Good (2,915 reviews) "Great stay for the price !!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elizabeth $85 nightly $97 total Mar 26 - Mar 27 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Buffalo-Airport-Hotel.h26001.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/10000000/9680000/9680000/9679916/b02fadd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/10000000/9680000/9680000/9679916/72bc6212.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/10000000/9680000/9680000/9679916/3f52c531.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/10000000/9680000/9680000/9679916/382726c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AAshram Hotel by Niagara River [](https://www.expedia.com/Niagara-Falls-Hotels-AAshram-Hotel-By-Niagara-River.h9679916.Hotel-Information) La Salle 7.8/10 Good (1,000 reviews) "Very clean & wide room. Close to the falls & market. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Hari Reshma $55 nightly $63 total Mar 30 - Mar 31 Total with taxes and fees [](https://www.expedia.com/Niagara-Falls-Hotels-AAshram-Hotel-By-Niagara-River.h9679916.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/19000000/18140000/18136300/18136290/3791ed95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/19000000/18140000/18136300/18136290/7ee1a124.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room (Cozy, Full/Full) | Hypo-allergenic bedding, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/19000000/18140000/18136300/18136290/739fabc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/19000000/18140000/18136300/18136290/0f54e2f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Richardson Hotel [](https://www.expedia.com/Buffalo-Hotels-Hotel-Henry-Urban-Resort.h18136290.Hotel-Information) Elmwood Bidwell 9.0/10 Wonderful (1,007 reviews) "The place is super clean, well equipped and there are a lot of great spots to explore within the property. Totally worth the visit and especially if you need a Hogwarts school kind of experience , then you would love it. Would recommend it to everyone. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rachana $147 nightly $172 total Mar 24 - Mar 25 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Hotel-Henry-Urban-Resort.h18136290.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-06&endDate=2026-04-07®ionId=6338362&adults=2&lodging=LODGE&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDepew-Lodges.d6338362-aaLodges.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDepew-Lodges.d6338362-aaLodges.Travel-Guide-Accommodation) ## Top Depew Hotel Reviews ![Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG](https://images.trvl-media.com/lodging/1000000/980000/973800/973773/ee46454f_y.jpg) ### Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG 10/10 Excellent "Good sized rooms, great for a quick night stay before a flight" [](https://expedia.com/Buffalo-Hotels-Holiday-Inn-Express-Hotel-Suites-Buffalo-Airport.h973773.Hotel-Information) ![Comfort Inn University](https://images.trvl-media.com/lodging/1000000/70000/66600/66581/2db1a2f1_y.jpg) ### Comfort Inn University 8/10 Good "Nice place " [](https://expedia.com/Buffalo-Hotels-Comfort-Inn-University.h66581.Hotel-Information) ![Aloft Buffalo Airport](https://images.trvl-media.com/lodging/10000000/9280000/9277900/9277828/9352f0af_y.jpg) ### Aloft Buffalo Airport 10/10 Excellent "I left my grey NDSU" [](https://expedia.com/Buffalo-Hotels-Aloft-Buffalo-Airport.h9277828.Hotel-Information) ![Holiday Inn Express Grand Island - Niagara Falls by IHG](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567279/3274a349_y.jpg) ### Holiday Inn Express Grand Island - Niagara Falls by IHG 10/10 Excellent "Friendly staff, clean room, loved the pool" [](https://expedia.com/Niagara-Falls-Hotels-Holiday-Inn-Express-Grand-Island-Niagara-Falls.h18567279.Hotel-Information) ![La Quinta Inn by Wyndham Buffalo Airport](https://images.trvl-media.com/lodging/1000000/30000/27600/27531/86fc2ca1_y.jpg) ### La Quinta Inn by Wyndham Buffalo Airport 10/10 Excellent "Clean and convenient." [](https://expedia.com/Buffalo-Hotels-La-Quinta-Inn-By-Wyndham-Buffalo-Airport.h27531.Hotel-Information) ![Wyndham Garden Buffalo Downtown](https://images.trvl-media.com/lodging/1000000/160000/159000/158959/dfd9177e_y.jpg) ### Wyndham Garden Buffalo Downtown 10/10 Excellent "The entire were polite and very helpful. " [](https://expedia.com/Buffalo-Hotels-Wyndham-Garden-Buffalo-Downtown.h158959.Hotel-Information) ![Holiday Inn Express Cheektowaga North East by IHG](https://images.trvl-media.com/lodging/9000000/8140000/8130600/8130557/d64d0a69_y.jpg) ### Holiday Inn Express Cheektowaga North East by IHG 10/10 Excellent "Clean and friendly staff. " [](https://expedia.com/Buffalo-Hotels-Holiday-Inn-Express-Cheektowaga-North-East.h8130557.Hotel-Information) ![Buffalo Airport Hotel](https://images.trvl-media.com/lodging/1000000/30000/26100/26001/19bd0f50_y.jpg) ### Buffalo Airport Hotel 8/10 Good "Clean comfortable room. Great atmosphere at the bar. Breakfast in the morning would be nice. Convenient location near the airport. " [](https://expedia.com/Buffalo-Hotels-Buffalo-Airport-Hotel.h26001.Hotel-Information) ![Garden Place Hotel](https://images.trvl-media.com/lodging/2000000/1070000/1060800/1060721/40afc3e4_y.jpg) ### Garden Place Hotel 6/10 Okay "The hotel ia absolutely beautiful. Once you walk in you are greeted by amazong staff and a huge chandelier. My room was clean up until it started flood. It didnt matter the room change my room flooded. My second room shower leaked from the cracks with my actual shower off. The doorway to enter/exit my room was soaked. Messed up a few socks and bottoms" [](https://expedia.com/Buffalo-Hotels-Garden-Place-Hotel.h1060721.Hotel-Information) ## Find out more about Depew ## Depew Lodges information | Number of reviews | 20,060 | | ----------------- | -------- | | Accommodation | 1 Lodges | | Lowest Price | $63 | | Highest Price | $267 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Hotels near Reinstein Woods Nature Preserve and Environmental Education Center ](https://www.expedia.com/Reinstein-Woods-Nature-Preserve-And-Environmental-Education-Center-Hotels.0-l553248621561173660-0.Travel-Guide-Filter-Hotels) - [Hotels near Buffalo-Depew Station ](https://www.expedia.com/Buffalo-Depew-Station-Hotels.d6194293.Travel-Guide-Hotels) - [Hotels near Buffalo Niagara Intl. ](https://www.expedia.com/Buffalo-Niagara-Intl-Airport-Hotels.0-aBUF-0.Travel-Guide-Filter-Hotels) - [Hotels near Stiglmeier Park ](https://www.expedia.com/Stiglmeier-Park-Hotels.0-l553248621558133903-0.Travel-Guide-Filter-Hotels) - 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