Title: Best Depew, NY Lodge Rentals from $63 | Expedia.com [Depew Travel Guide](https://expedia.com/Depew.dx6338362)[Hotels in Depew](https://expedia.com/Depew-Hotels.d6338362.Travel-Guide-Hotels)[Vacation Rentals in Depew](https://expedia.com/Depew-Vacation-Rentals.d6338362.Travel-Guide-VacationRentals)[Flights to Depew](https://expedia.com/Cheap-Flights-To-Depew.d6338362.Travel-Guide-Flights)[Things to do in Depew](https://expedia.com/Things-To-Do-In-Depew.d6338362.Travel-Guide-Activities)[Car Rentals in Depew](https://expedia.com/Car-Rentals-In-Depew.d6338362.Car-Rental-Guide)[Depew Vacation Packages](https://expedia.com/Depew.d6338362.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_bundle_and_save.svg) ### Bundle & Save Get more, spend less whenever you see Bundle & Save deals - ![](https://a.travel-assets.com/travel-assets-manager/pictograms-expedia/light__onekey.svg) ### OneKeyCash Earn OneKeyCash on all your eligible bookings - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_ftc.svg) ### Upfront pricing We are not like the others - we include taxes and fees ## Check prices for these dates Next weekend [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=6338362&startDate=2026-04-03&endDate=2026-04-05&adults=2&lodging=LODGE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=6338362&startDate=2026-04-10&endDate=2026-04-12&adults=2&lodging=LODGE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Apr 24 - Apr 26](https://www.expedia.com/Hotel-Search?regionId=6338362&startDate=2026-04-24&endDate=2026-04-26&adults=2&lodging=LODGE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [May 22 - May 24](https://www.expedia.com/Hotel-Search?regionId=6338362&startDate=2026-05-22&endDate=2026-05-24&adults=2&lodging=LODGE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) No exact matches found, but these alternatives could be just right ## Recommended hotels in Depew ![Interior](https://images.trvl-media.com/lodging/128000000/127200000/127194500/127194430/a07a74c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/128000000/127200000/127194500/127194430/6af93d88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/128000000/127200000/127194500/127194430/eb4c180e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/128000000/127200000/127194500/127194430/bf112f42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 3-bedroom house in close to the airport Buffalo family- friendly no pets allowed [](https://www.expedia.com/Buffalo-Hotels-3-Bedroom-House-In-Close-To-The-Airport-Buffalo-Family-Friendly-No-Pets-Allowed.h127194430.Hotel-Information) Depew $239 nightly $267 total Mar 25 - Mar 26 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-3-Bedroom-House-In-Close-To-The-Airport-Buffalo-Family-Friendly-No-Pets-Allowed.h127194430.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567279/3274a349.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567279/ea0d463b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567279/2685a465.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567279/3e0bf4eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Grand Island - Niagara Falls by IHG [](https://www.expedia.com/Niagara-Falls-Hotels-Holiday-Inn-Express-Grand-Island-Niagara-Falls.h18567279.Hotel-Information) Grand Island 9.0/10 Wonderful (1,729 reviews) "Large rooms, great breakfast, very friendly staff, location was great " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Diane $87 nightly $99 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Niagara-Falls-Hotels-Holiday-Inn-Express-Grand-Island-Niagara-Falls.h18567279.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/10000/5200/5183/46db5598.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/5200/5183/73648063.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5200/5183/1726aaa7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5200/5183/c135a4a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Summit Inn [](https://www.expedia.com/Niagara-Falls-Hotels-Best-Western-Summit-Inn.h5183.Hotel-Information) Niagara Falls 8.6/10 Excellent (1,447 reviews) "The hotel was a great value - very clean and well kept. The staff were friendly and helpful. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elaine $72 nightly $82 total Mar 25 - Mar 26 Total with taxes and fees [](https://www.expedia.com/Niagara-Falls-Hotels-Best-Western-Summit-Inn.h5183.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/970000/968200/968172/2e04419a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![55-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/1000000/970000/968200/968172/32845daa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/970000/968200/968172/8fe475d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed with Sofa bed, Non Smoking (King Study) | Hypo-allergenic bedding, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/970000/968200/968172/104f9b47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn East Aurora [](https://www.expedia.com/East-Aurora-Hotels-Hampton-Inn-East-Aurora.h968172.Hotel-Information) East Aurora 9.4/10 Exceptional (1,001 reviews) "Incredibly friendly staff at check in. Room was beautiful and very clean. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Linda $130 nightly $148 total Apr 2 - Apr 3 Total with taxes and fees [](https://www.expedia.com/East-Aurora-Hotels-Hampton-Inn-East-Aurora.h968172.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/100000000/99810000/99802700/99802648/b3c0a8a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/100000000/99810000/99802700/99802648/4eac0a0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking (with Sofabed) | Individually furnished, desk, laptop workspace, free WiFi](https://images.trvl-media.com/lodging/100000000/99810000/99802700/99802648/1eafede6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/100000000/99810000/99802700/99802648/dec807b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Buffalo Inn & Suites [](https://www.expedia.com/Eva-Hotel.h99802648.Hotel-Information) Buffalo 8.8/10 Excellent (899 reviews) "Great stay staff and property we love it " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Ezio $100 nightly $114 total Mar 30 - Mar 31 Total with taxes and fees [](https://www.expedia.com/Eva-Hotel.h99802648.Hotel-Information) ![Garden](https://images.trvl-media.com/lodging/8000000/7910000/7900500/7900412/1a361d5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/8000000/7910000/7900500/7900412/e8b3cf14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/8000000/7910000/7900500/7900412/c3686c83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Double Beds, Kitchen | Living room | LCD TV](https://images.trvl-media.com/lodging/8000000/7910000/7900500/7900412/bdc4a4c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clarence Inn [](https://www.expedia.com/Buffalo-Hotels-Clarence-Inn.h7900412.Hotel-Information) Clarence 8.2/10 Very Good (297 reviews) "Great service quiet place and friendly people." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Larry $80 nightly $90 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Clarence-Inn.h7900412.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/8000000/7520000/7511900/7511809/2864591b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Suite, 1 Bedroom | Premium bedding, pillowtop beds, individually furnished, desk](https://images.trvl-media.com/lodging/8000000/7520000/7511900/7511809/1c0281cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/8000000/7520000/7511900/7511809/94dc4133.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/8000000/7520000/7511900/7511809/18b78331.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Roycroft Inn [](https://www.expedia.com/East-Aurora-Hotels-Roycroft-Inn.h7511809.Hotel-Information) East Aurora 9.6/10 Exceptional (864 reviews) "Beautiful & historic inn with a wonderful staff & restaurant. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen $149 nightly $166 total Apr 16 - Apr 17 Total with taxes and fees [](https://www.expedia.com/East-Aurora-Hotels-Roycroft-Inn.h7511809.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/10000000/9750000/9743100/9743017/27ee7ea2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Royal Suite, 1 King Bed, Non-Smoking | In-room safe, desk, laptop workspace, soundproofing](https://images.trvl-media.com/lodging/10000000/9750000/9743100/9743017/feccd0a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/10000000/9750000/9743100/9743017/ed49d5cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/10000000/9750000/9743100/9743017/a36a3e4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Salvatores Grand Hotel [](https://www.expedia.com/Buffalo-Hotels-Salvatores-Grand-Hotel.h9743017.Hotel-Information) Buffalo 9.6/10 Exceptional (1,004 reviews) "Beautiful hotel , excellent food, worth every penny. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrea $129 nightly $147 total Mar 25 - Mar 26 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Salvatores-Grand-Hotel.h9743017.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/94000000/93470000/93463700/93463671/c4fa613a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/94000000/93470000/93463700/93463671/2293699f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/94000000/93470000/93463700/93463671/f8a867f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/94000000/93470000/93463700/93463671/c8535cdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 420 Friendly 3 bedroom upstairs apartment. Street parking only. [](https://www.expedia.com/Buffalo-Hotels-420-Friendly-3-Bedroom-Upstairs-Apartment-Street-Parking-Only.h93463671.Hotel-Information) Seneca 9.4/10 Exceptional (68 reviews) "Excellent stay! All the things we needed and then some :) highly recommend! Will be staying here anytime I am in the area!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kerry G. $195 nightly $199 total Apr 19 - Apr 20 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-420-Friendly-3-Bedroom-Upstairs-Apartment-Street-Parking-Only.h93463671.Hotel-Information) ![Standard Room, 1 King Bed, Non Smoking (Ground Floor, Pets Allowed) | 1 bedroom, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/2100/2071/fc11b7d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/2100/2071/a26a08df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/2100/2071/b47b27ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/2100/2071/19db4ac2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Darien Lakes [](https://www.expedia.com/Corfu-Hotels-Econo-Lodge-Darien-Lakes.h2071.Hotel-Information) Corfu 7.8/10 Good (813 reviews) "Staff were prompt with check-in and very direct. It was helpful. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anna $68 nightly $75 total Mar 30 - Mar 31 Total with taxes and fees [](https://www.expedia.com/Corfu-Hotels-Econo-Lodge-Darien-Lakes.h2071.Hotel-Information) ![Standard Studio Suite, 1 King Bed, Jetted Tub | In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/8000000/7670000/7663400/7663327/18b8438d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Studio Suite, 1 King Bed, Jetted Tub | In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/8000000/7670000/7663400/7663327/44216c33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/8000000/7670000/7663400/7663327/8334e598.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/8000000/7670000/7663400/7663327/f038d62d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lockport Inn & Suites [](https://www.expedia.com/Niagara-Falls-Hotels-Lockport-Inn-Suites.h7663327.Hotel-Information) Lockport 9.2/10 Wonderful (1,000 reviews) "Very nice family-run cozy stay." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Leonardo $99 nightly $112 total Mar 25 - Mar 26 Total with taxes and fees [](https://www.expedia.com/Niagara-Falls-Hotels-Lockport-Inn-Suites.h7663327.Hotel-Information) ![Suite, 1 King Bed with Sofa bed, Non Smoking | Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/90000/85100/85007/9d03cce3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/85100/85007/ae021a7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/90000/85100/85007/d35175de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/90000/85100/85007/77375700.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn & Suites Buffalo Airport [](https://www.expedia.com/Buffalo-Hotels-Sleep-Inn-Suites-Buffalo-Airport.h85007.Hotel-Information) Buffalo 8.0/10 Very Good (2,020 reviews) "Nice hotel" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Nilanjan $74 nightly $85 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Sleep-Inn-Suites-Buffalo-Airport.h85007.Hotel-Information) ![Deluxe Room, 2 Queen Beds, Non Smoking | Desk, iron/ironing board, free cribs/infant beds, rollaway beds](https://images.trvl-media.com/lodging/2000000/1500000/1497100/1497090/00561ac2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1500000/1497100/1497090/af522590.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, Non Smoking (2 King Beds) | Desk, iron/ironing board, free cribs/infant beds, rollaway beds](https://images.trvl-media.com/lodging/2000000/1500000/1497100/1497090/ff5fa686.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1500000/1497100/1497090/74836d03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn & Suites by Wyndham Niagara Falls/Buffalo [](https://www.expedia.com/Niagara-Falls-Hotels-Days-Inn-Suites-By-Wyndham-Niagara-Fallsbuffalo.h1497090.Hotel-Information) Niagara Falls 8.0/10 Very Good (1,003 reviews) "Wonderful stay will stay again" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) christine $68 nightly $77 total Mar 31 - Apr 1 Total with taxes and fees [](https://www.expedia.com/Niagara-Falls-Hotels-Days-Inn-Suites-By-Wyndham-Niagara-Fallsbuffalo.h1497090.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/48000000/47030000/47021400/47021354/09462364.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/48000000/47030000/47021400/47021354/5de7a4e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/48000000/47030000/47021400/47021354/eaaa575c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/48000000/47030000/47021400/47021354/7ab4a0dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Amherst - Lockport by IHG [](https://www.expedia.com/Buffalo-Hotels-Holiday-Inn-Express-Lockport.h47021354.Hotel-Information) Lockport 9.2/10 Wonderful (765 reviews) "Clean and comfortable accommodations, friendly staff and a great breakfast spread!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrea $111 nightly $125 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Holiday-Inn-Express-Lockport.h47021354.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/560000/558600/558591/139ee991.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 6:30 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/560000/558600/558591/b33f35a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/560000/558600/558591/a196e14b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business center](https://images.trvl-media.com/lodging/1000000/560000/558600/558591/295249d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Near Walden Galleria Mall [](https://www.expedia.com/Buffalo-Hotels-Quality-Inn-Near-Walden-Galleria-Mall.h558591.Hotel-Information) Buffalo 8.0/10 Very Good (1,009 reviews) "Good location for our visit for a concert at Keybank. Room was clean, bed was comfortable." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Melissa $89 nightly $101 total Apr 2 - Apr 3 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Quality-Inn-Near-Walden-Galleria-Mall.h558591.Hotel-Information) ![Lunch and dinner served, American cuisine](https://images.trvl-media.com/lodging/1000000/30000/26100/26001/19bd0f50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business center](https://images.trvl-media.com/lodging/1000000/30000/26100/26001/7585a4c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/30000/26100/26001/12050768.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed with Sofa bed | In-room safe, desk, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/26100/26001/52bfdeb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Buffalo Airport Hotel [](https://www.expedia.com/Buffalo-Hotels-Buffalo-Airport-Hotel.h26001.Hotel-Information) Buffalo 8.0/10 Very Good (2,915 reviews) "Great stay for the price !!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elizabeth $85 nightly $97 total Mar 26 - Mar 27 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Buffalo-Airport-Hotel.h26001.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/10000000/9680000/9680000/9679916/b02fadd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/10000000/9680000/9680000/9679916/f6fd68ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/10000000/9680000/9680000/9679916/72bc6212.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/10000000/9680000/9680000/9679916/382726c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AAshram Hotel by Niagara River [](https://www.expedia.com/Niagara-Falls-Hotels-AAshram-Hotel-By-Niagara-River.h9679916.Hotel-Information) La Salle 7.8/10 Good (1,000 reviews) "Very clean & wide room. Close to the falls & market. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Hari Reshma $55 nightly $63 total Mar 30 - Mar 31 Total with taxes and fees [](https://www.expedia.com/Niagara-Falls-Hotels-AAshram-Hotel-By-Niagara-River.h9679916.Hotel-Information) ![Deluxe Room, 2 Double Beds (Smoke Free) | 1 bedroom, desk, blackout drapes, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/900/816/dec8cb3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, blackout drapes, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/900/816/d1c4663a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/900/816/760d0b9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/900/816/b68133b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Buffalo - Niagara Airport [](https://www.expedia.com/Buffalo-Hotels-Red-Roof-Inn-Buffalo-Niagara-Airport.h816.Hotel-Information) Bowmansville 7.2/10 Good (1,001 reviews) "Parking was easy. Room was clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gary $60 nightly $69 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Red-Roof-Inn-Buffalo-Niagara-Airport.h816.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1820000/1818500/1818414/b908b841.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1820000/1818500/1818414/9308a223.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking | Hypo-allergenic bedding, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1820000/1818500/1818414/9d237184.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/2000000/1820000/1818500/1818414/9a4a31e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Lackawanna [](https://www.expedia.com/Buffalo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Lackawanna.h1818414.Hotel-Information) Buffalo 6.4/10 (1,001 reviews) "Good atmosphere " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Henry $89 nightly $102 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Lackawanna.h1818414.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/900000/890400/890385/023ac782.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking | Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/900000/890400/890385/3d3d0925.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/900000/890400/890385/1e4370be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/1000000/900000/890400/890385/2ac00d85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge At The Falls North [](https://www.expedia.com/Niagara-Falls-Hotels-Econo-Lodge-At-The-Falls-North.h890385.Hotel-Information) La Salle 7.8/10 Good (1,113 reviews) "Good staff..nice clean rooms..comfy beds.. one of the best econolodges ever" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aaron $63 nightly $72 total Mar 30 - Mar 31 Total with taxes and fees [](https://www.expedia.com/Niagara-Falls-Hotels-Econo-Lodge-At-The-Falls-North.h890385.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-07&endDate=2026-04-08®ionId=6338362&adults=2&lodging=LODGE&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDepew-Lodges.d6338362-aaLodges.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDepew-Lodges.d6338362-aaLodges.Travel-Guide-Accommodation) ## Top Depew Hotel Reviews ![M Hotel Buffalo](https://images.trvl-media.com/lodging/1000000/20000/11300/11231/2c4d5593_y.jpg) ### M Hotel Buffalo 10/10 Excellent "Beautiful Stay " [](https://expedia.com/Buffalo-Hotels-Millennium-Buffalo.h11231.Hotel-Information) ![Wyndham Garden Buffalo Downtown](https://images.trvl-media.com/lodging/1000000/160000/159000/158959/dfd9177e_y.jpg) ### Wyndham Garden Buffalo Downtown 6/10 Okay "Basics but clean" [](https://expedia.com/Buffalo-Hotels-Wyndham-Garden-Buffalo-Downtown.h158959.Hotel-Information) ![Holiday Inn Express Grand Island - Niagara Falls by IHG](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567279/3274a349_y.jpg) ### Holiday Inn Express Grand Island - Niagara Falls by IHG 10/10 Excellent "This was a great hotel. I know it was off-season, but the staff was awesome. The rooms were clean. Like this hotel very much." [](https://expedia.com/Niagara-Falls-Hotels-Holiday-Inn-Express-Grand-Island-Niagara-Falls.h18567279.Hotel-Information) ![Comfort Inn University](https://images.trvl-media.com/lodging/1000000/70000/66600/66581/2db1a2f1_y.jpg) ### Comfort Inn University 10/10 Excellent "Every single explote just Wounderful " [](https://expedia.com/Buffalo-Hotels-Comfort-Inn-University.h66581.Hotel-Information) ![La Quinta Inn by Wyndham Buffalo Airport](https://images.trvl-media.com/lodging/1000000/30000/27600/27531/86fc2ca1_y.jpg) ### La Quinta Inn by Wyndham Buffalo Airport 6/10 Okay "Check in was adequate. Not a warm or friendly welcome. Just enough to make the transaction. There were random ppl hanging out in the halls and lobby, which made me alert travelling with 2 young girls. I didnt feel unsafe, but not super safe like I have at other hotels in the area. The hall outside our room smelled like a mix of cigarettes/weed and air freshner. Breakfast was incredibly disappointing. 815 am, no sausages, eggs soggy slop bread was hard from being left open. No yogurt or fruit. My daughter is celiac and had limited options. I asked the attendant if there was any optionsnor more yogurt of fruit. He looked over and said. No. I suggested he check out back. He did. Came back and said no. Blamed there being no delivery. Not empathetic. He truly did not care and continued mopping spilked milk. It was truly disappointing. " [](https://expedia.com/Buffalo-Hotels-La-Quinta-Inn-By-Wyndham-Buffalo-Airport.h27531.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Buffalo Amherst](https://images.trvl-media.com/lodging/25000000/24730000/24723600/24723591/6499bfe4_y.jpg) ### La Quinta Inn & Suites by Wyndham Buffalo Amherst 10/10 Excellent "Yes needs were met " [](https://expedia.com/Buffalo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Buffalo-Amherst.h24723591.Hotel-Information) ![Holiday Inn Express Cheektowaga North East by IHG](https://images.trvl-media.com/lodging/9000000/8140000/8130600/8130557/d64d0a69_y.jpg) ### Holiday Inn Express Cheektowaga North East by IHG 6/10 Okay "Pool water was barely warm, but the room itself was quite cold. Got a room specifically to swim with my grandbaby, was disappointed. Room was clean and nice. " [](https://expedia.com/Buffalo-Hotels-Holiday-Inn-Express-Cheektowaga-North-East.h8130557.Hotel-Information) ![Hyatt Regency Buffalo / Hotel and Conference Center](https://images.trvl-media.com/lodging/1000000/30000/23200/23101/00561234_y.jpg) ### Hyatt Regency Buffalo / Hotel and Conference Center 8/10 Good "too hot in the room. could not adjust the temperature satisfactorily" [](https://expedia.com/Buffalo-Hotels-Hyatt-Regency-Buffalo-Hotel-And-Conference-Center.h23101.Hotel-Information) ![The Mansion On Delaware Ave](https://images.trvl-media.com/lodging/1000000/700000/692700/692610/1225a495_y.jpg) ### The Mansion On Delaware Ave 8/10 Good "Very nice stay in a homey inn and located in a great location. The room as spacious and comfy. Bed was a bit too soft for my husband and the Wi-Fi was very spotty. Some of the carpeting on stairs is worn and could use an upgrade. And you can hear voices pretty loudly in the hallway. But we still enjoyed our brief two night stay. Breakfast was made to order sweet or savory and pretty good. Everything is pretty much self serve(ie there are really any “butlers”), but that suits us just fine. Parking is tight in the lot outside the inn, but there is also a spacious lot across the street. We plan to stay again next month. " [](https://expedia.com/Buffalo-Hotels-The-Mansion-On-Delaware-Ave.h692610.Hotel-Information) ## Find out more about Depew ## Depew Lodges information | Number of reviews | 20,949 | | ----------------- | -------- | | Accommodation | 1 Lodges | | Lowest Price | $63 | | Highest Price | $267 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Hotels near Reinstein Woods Nature Preserve and Environmental Education Center ](https://www.expedia.com/Reinstein-Woods-Nature-Preserve-And-Environmental-Education-Center-Hotels.0-l553248621561173660-0.Travel-Guide-Filter-Hotels) - [Hotels near Buffalo-Depew Station ](https://www.expedia.com/Buffalo-Depew-Station-Hotels.d6194293.Travel-Guide-Hotels) - [Hotels near Buffalo Niagara Intl. ](https://www.expedia.com/Buffalo-Niagara-Intl-Airport-Hotels.0-aBUF-0.Travel-Guide-Filter-Hotels) - [Hotels near Stiglmeier Park ](https://www.expedia.com/Stiglmeier-Park-Hotels.0-l553248621558133903-0.Travel-Guide-Filter-Hotels) - 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