Durham, ME

Travel Guide

Where to stay in Durham

Find the best Durham areas and neighborhoods for the activities you enjoy most. Learn more about Durham
Learn more about Durham

West Durham

Check out nearby sights like Bradbury Mountain State Park while you're spending some time in West Durham and the surrounding area.

Portland Regency Hotel & Spa

Portland Regency Hotel & Spa

3.5 out of 5
20 Milk Street Portland ME
$149 nightly
The price is $165 total per night from Nov 3 to Nov 4
$165 total
Nov 3 - Nov 4
Total with taxes and fees
Book a stay at this spa hotel in Portland. Enjoy free WiFi, a full-service spa, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in ...
9.4/10 Exceptional! (1,783 reviews)
"Beautiful hotel, great location."

Reviewed on Oct 22, 2026

Portland Regency Hotel & Spa
Hampton Inn Portland Downtown - Waterfront

Hampton Inn Portland Downtown - Waterfront

2.5 out of 5
209 Fore St Portland ME
$98 nightly
The price is $108 total per night from Nov 18 to Nov 19
$108 total
Nov 18 - Nov 19
Total with taxes and fees
Book a stay at this business-friendly hotel in Portland. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
Hampton Inn Portland Downtown - Waterfront
Cambria Hotel Portland Downtown-Old Port

Cambria Hotel Portland Downtown-Old Port

3 out of 5
25 HANCOCK STREET Portland ME
$126 nightly
The price is $139 total per night from Nov 1 to Nov 2
$139 total
Nov 1 - Nov 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Portland. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the restaurant ...
9.2/10 Wonderful! (1,341 reviews)
"Beautiful room with a great view!!"

Reviewed on Oct 21, 2026

Cambria Hotel Portland Downtown-Old Port
See all 1,709 properties in Durham
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Quiet, comfy guest quarters just three miles from Freeport! And only one unit!

Quiet, comfy guest quarters just three miles from Freeport! And only one unit!

Durham ME
Stay at this apartment in Durham. Enjoy free WiFi, patios, and an in-room coffeemaker. Popular attractions LL Bean Flagship Store and Bradbury Mountain State ...
10/10 Exceptional! (65 reviews)
"The location was great, the space was just what we were looking for and Wayne was very accommodating and easy to communicate with. 10/10 would rent here again!"

Reviewed on Oct 12, 2026

Quiet, comfy guest quarters just three miles from Freeport! And only one unit!
Spacious Craftsman w/ Casco Bay Views. Hot Tub, Patio, Easy Access to Old Port

Spacious Craftsman w/ Casco Bay Views. Hot Tub, Patio, Easy Access to Old Port

Portland ME
Book a stay at this family-friendly vacation home in Portland. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Cross Insurance Arena and ...
10/10 Exceptional! (84 reviews)
"Everything worked well and the home was well-provisioned and equipped. The space was perfect for out group."

Reviewed on Oct 19, 2026

Spacious Craftsman w/ Casco Bay Views. Hot Tub, Patio, Easy Access to Old Port
Charming Studio apartment with WiFi, AC in welcoming Portland

Charming Studio apartment with WiFi, AC in welcoming Portland

Portland ME
Stay at this apartment in Portland. Enjoy air conditioning. Popular attractions Cross Insurance Arena and Maine Mall are located nearby.
Charming Studio apartment with WiFi, AC in welcoming Portland
See all properties in Durham
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

When is the best time to visit Durham?
The best time to visit Durham is from June through August, when the weather is generally pleasant for exploring. For travelers seeking fewer crowds and better value, the quieter months of November through January offer a more relaxed experience, often with cooler temperatures.
What cuisines can you find in Durham?
In Durham you can find Mexican cuisine, with dishes like tacos, burritos, and quesadillas. Travelers can also enjoy a variety of Asian options including Chinese, Japanese, and Thai, alongside Southern soul food, Italian, and Mediterranean dishes. The area also offers a selection of coffee shops and cocktail lounges.
Can I book a refundable hotel in Durham?
Yes, Expedia offers many flexible booking options, and you can look for refundable hotels in Durham by entering your dates and using the refundable or fully refundable filter. Always check the hotel's cancellation policy before you book, since terms can vary by hotel, and visit Expedia help center for further details.
Why book a trip to Durham with Expedia?
Expedia makes it easier to plan your Durham trip with travel tools, flexible search options, and bookable trip components all in one place. You can organize your plans in one account and use Expedia to help build a trip that fits your budget and travel style. Find out more about how by visiting Expedia's Trip Planner page.
Should I stay in a hotel or vacation rental in Durham?
The best choice depends on your travel style. Hotels in Durham can be a good fit for convenience, on-site amenities, and shorter stays, while vacation rentals may offer more space, privacy, and home-style amenities for longer trips, families, or groups. With Expedia, you can compare both options side by side, read traveler reviews, and filter by amenities to find the right fit for your trip.
How can I manage my Durham trip on Expedia?
Once you've booked your Durham trip, you can manage it through your Expedia account or the Expedia app. You can view your itinerary, access booking details, make eligible changes, and check for updates in My Trips. The Expedia app can also help you stay organized while you travel.
What if I need help during my Durham trip?
Expedia offers customer support before, during, and after your Durham trip. If your plans change or something unexpected happens, you can review your booking in My Trips and use Expedia help center channels for help with eligible changes, cancellations, or travel issues.
How can Expedia help me plan my first trip to Durham?
If it's your first trip to Durham, Expedia can help you plan by bringing together stays, flights, activities, traveler reviews, and trip-planning tools in one place. With Expedia's Trip Planner you can compare options, read reviews from other travelers, and build an itinerary that matches your interests and budget.
How can I save on my Durham hotel booking with Expedia?
Join One Key™ for free to unlock instant discounts with Member Prices on select hotels. You can also earn and use OneKeyCash™* on eligible bookings on Expedia. Booking in advance is usually another great way to save on your Durham hotel.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.

Cities near Durham

A red car driving on a street with a brick building and a church in the background.

Brunswick

An aerial view of a town with a prominent historic building, a central intersection, and surrounding greenery.

Auburn

A brick building with green shutters, a tree with red leaves, and a street with people walking.

Freeport

Large rocks covered with green seaweed.

Topsham

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