Top Hampton County Hotels: 2026 Best Hotels in Hampton County

Upfront pricing
Our total price for your stay includes taxes and fees
Treat yourself
Save 10% or more on over 100,000 hotels worldwide with Member Prices
Learn about One Key
Be picky
Search almost a million properties worldwide

Top cities in Hampton County

A white colonial-style building with columns and a covered porch.

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Our top choices for Hampton County hotels

A spacious lobby with a modern design, featuring a reception desk, comfortable seating, and large windows offering a view of the outdoors.

1. Quality Inn Yemassee - Point South I-95

Yemassee

Claudia

$58 nightly

Dec 6 - Dec 7

Total with taxes and fees

A hotel with a modern design, featuring a parking area with several cars and a landscaped entrance.

2. Hampton Inn Yemassee/Point South

Yemassee

Philip

$139 nightly

Dec 16 - Dec 17

Total with taxes and fees

A hotel room with a bed, bedside tables, a large mirror, a bathtub, a sofa, and a television.

3. OYO Hampton South Carolina Hwy 278

Hampton

Allison

$150 nightly

Nov 16 - Nov 17

Total with taxes and fees

A Red Roof Inn & Suites lobby with a stone wall, leather sofas, armchairs, and a large potted plant.

4. Red Roof Inn Yemassee

Yemassee

DeAngelo

$74 nightly

Nov 16 - Nov 17

Total with taxes and fees

A spacious lobby with a coffee table, sofas, and a television. Large windows offer views of palm trees and a parking lot.

5. Econo Lodge Yemassee

Yemassee

jeff

$47 nightly

Dec 6 - Dec 7

Total with taxes and fees

A kitchen with a microwave, coffee maker, and food containers on the counter.

6. Knights Inn Yemassee

Yemassee

James

$48 nightly

Nov 30 - Dec 1

Total with taxes and fees

A hotel room with a large bed, two bedside lamps, a chair, a large window with curtains, and a wall-mounted air conditioner.

7. Palmetto Inn

Estill

JORGE

$75 nightly

Nov 16 - Nov 17

Total with taxes and fees

A hotel room with a bed, a desk with a phone, a chair, a round ottoman, a painting, a lamp, and a window with curtains.

8. Best Western Point South

Yemassee

Bradford

9. Motel 6 Yemassee, SC

Yemassee

KENNETH

A kitchen with white cabinets, a wooden countertop, a sink, and a refrigerator with a home-themed cover.

10. Welcome to the Honey House in beautiful Hampton South Carolina

Hampton

Darren P.

An outdoor seating area with Adirondack chairs and a table, surrounded by trees and a body of water.

11. Outdoor Oasis + Tidal Creek Views: Yemassee Escape

Yemassee

A wooden pathway leading through a wooded area with tall trees and a grassy field in the background.

12. Lowcountry Orchard Getaway: 4-bedroom house in lovely Yemassee, SC Sleeps 12

Yemassee

C J.

$333 nightly

Nov 22 - Nov 23

Total with taxes and fees

A hotel room with a large bed, a sitting area with a chair, a wooden wardrobe, a bathroom with a bathtub, and a mirror.

13. 3 Queen Bed | Hampton

Hampton, SC

Anonymous traveler

$198 nightly

Nov 16 - Nov 17

Total with taxes and fees

A hotel lobby with a reception desk, a blue carpet, a glass display case with flowers, and a clock on the wall.

14. King Bed Non-Smoking

Hampton, SC

Anonymous traveler

$146 nightly

Nov 16 - Nov 17

Total with taxes and fees

A modern kitchen with dark cabinets, stainless steel appliances, a granite countertop, and wooden flooring.

15. 3-bedroom house in peaceful Hampton with Central AC-Cool/Heat

Hampton

A kitchen with wooden cabinets, a microwave, and a bar stool.

16. Margie & Hank's 4BR | Fenced Yard | Pet Friendly

Varnville

A hotel reception area with a blue carpet, a red vending machine, and a glass display case with flowers.

17. 2 Queen Beds Non-Smoking

Hampton, SC

Anonymous traveler

$159 nightly

Nov 16 - Nov 17

Total with taxes and fees

18. 3 Queen Beds Smoking

Hampton, SC

Anonymous traveler

$196 nightly

Nov 16 - Nov 17

Total with taxes and fees

19. King Bed Accessible Non-Smoking

Hampton, SC

Anonymous traveler

$148 nightly

Nov 16 - Nov 17

Total with taxes and fees

20. 1 Suite King Bed Non-Smoking Jacuzzi Tub

Hampton, SC

Anonymous traveler

$227 nightly

Nov 16 - Nov 17

Total with taxes and fees

View all properties

Compare top hotels in Hampton County

Quality Inn Yemassee - Point South I-95 2.5 star property Yemassee View	Hampton Inn Yemassee/Point South 2.5 star property Yemassee View	OYO Hampton South Carolina Hwy 278 2.0 star property Hampton View	Red Roof Inn Yemassee 2.0 star property Yemassee View	Econo Lodge Yemassee 2.0 star property Yemassee View
7.6 Good 346 reviews	8.8 Excellent 855 reviews	8.2 Very good 149 reviews	7.6 Good 682 reviews	7.0 Good 162 reviews
$58 nightly The price is $66 Dec 6 - Dec 7 Total with taxes and fees	$139 nightly The price is $158 Dec 16 - Dec 17 Total with taxes and fees	$150 nightly The price is $165 Nov 16 - Nov 17 Total with taxes and fees	$74 nightly The price is $84 Nov 16 - Nov 17 Total with taxes and fees	$47 nightly The price is $53 Dec 6 - Dec 7 Total with taxes and fees
Yes, Breakfast included No Pool No Spa Yes, Pet friendly Yes, WiFi included Yes, Parking	Yes, Breakfast included Yes, Pool No Spa Yes, Pet friendly Yes, WiFi included Yes, Parking	No Breakfast included No Pool No Spa No Pet friendly Yes, WiFi included Yes, Parking	Yes, Breakfast included Yes, Pool No Spa Yes, Pet friendly Yes, WiFi included Yes, Parking	No Breakfast included No Pool No Spa Yes, Pet friendly Yes, WiFi included Yes, Parking