Ladys Island Vacation Rentals

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Our top choices for Ladys Island vacation rentals

Relax under the Shade of a Live Oak! MCRD Paris Island and MCAS 10 Minute Drive

Relax under the Shade of a Live Oak! MCRD Paris Island and MCAS 10 Minute Drive
Beaufort
10.0 out of 10, Exceptional, (6 reviews)
"Great place, very spacious and clean"
United States
James R.
$367 nightly
The price is $403
Mar 1 - Mar 2
Total with taxes and fees
Relax under the Shade of a Live Oak! MCRD Paris Island and MCAS 10 Minute Drive

Amazing Airstream, Beaufort, SC-Enjoy the Journey!

Amazing Airstream, Beaufort, SC-Enjoy the Journey!
Beaufort
9.6 out of 10, Exceptional, (24 reviews)
"We love this place. I stay here frequently and enjoy every time. Close and convenient to everything Beaufort has to offer."
United States
Nate P.
$170 nightly
The price is $187
Feb 27 - Feb 28
Total with taxes and fees
Amazing Airstream, Beaufort, SC-Enjoy the Journey!

Tranquility by the Beach 1st Fl Sleeps 6,King Bed

Tranquility by the Beach 1st Fl Sleeps 6,King Bed
Mid Island
9.4 out of 10, Exceptional, (55 reviews)
"Relaxing and comfortable stay"
United States
cheryl j.
$261 nightly
The price is $287
Mar 1 - Mar 2
Total with taxes and fees
Tranquility by the Beach 1st Fl Sleeps 6,King Bed

Gentleman Pirate (Ocean Views!)

Gentleman Pirate (Ocean Views!)
Edisto Beach
10.0 out of 10, Exceptional, (17 reviews)
"Great vacation home!"
United States
Samuel J.
$406 nightly
The price is $455
Feb 27 - Feb 28
Total with taxes and fees
Gentleman Pirate (Ocean Views!)

Bright Ocean View Condo Steps From Dining, Golf, Pool, & Beach

Bright Ocean View Condo Steps From Dining, Golf, Pool, & Beach
3.5 star property
Fripp Island
10.0 out of 10, Exceptional, (2 reviews)
"Amazing location and views. Very nice. Definitely recommend!"
United States
Christopher
$560 nightly
The price is $616
Mar 17 - Mar 18
Total with taxes and fees
Bright Ocean View Condo Steps From Dining, Golf, Pool, & Beach

Oceanside, steps to the Beach, pets considered, cards avail, Beach Club Complex

Oceanside, steps to the Beach, pets considered, cards avail, Beach Club Complex
Saint Helena Island
8.4 out of 10, Very Good, (38 reviews)
"Greta location, right by the beach."
United States
javier m.
$285 nightly
The price is $314
Feb 27 - Feb 28
Total with taxes and fees
Oceanside, steps to the Beach, pets considered, cards avail, Beach Club Complex

522 Sunsuite - Resort Access Included!

522 Sunsuite - Resort Access Included!
Fripp Island
9.6 out of 10, Exceptional, (4 reviews)
"Relaxation was much needed and host was very accommodating and made check in easy. The room was clean, and perfect for our stay. The location was perfect. "
United States
Felicia R.
$307 nightly
The price is $337
Feb 27 - Feb 28
Total with taxes and fees
522 Sunsuite - Resort Access Included!

Mariners' Nautical Nest on Port Royal's Battery Creek

Mariners' Nautical Nest on Port Royal's Battery Creek
Beaufort
9.8 out of 10, Exceptional, (30 reviews)
"We so loved our stay! Our stay was AMAZING! Great location, great views, and the downtown area is very close and easy to get to. Cannot wait to rebook your place!! "
United States
Glenn G.
$231 nightly
The price is $254
Mar 8 - Mar 9
Total with taxes and fees
Mariners' Nautical Nest on Port Royal's Battery Creek

Coastline Cottage with Breathtaking Ocean Views On Fripp Island Wi-Fi, Golf Cart

Coastline Cottage with Breathtaking Ocean Views On Fripp Island Wi-Fi, Golf Cart
Saint Helena Island
10.0 out of 10, Exceptional, (28 reviews)
"Such a great place for a get away! Communication with the host was easy and we plan to stay again! "
United States
Samantha E.
$367 nightly
The price is $404
Mar 9 - Mar 10
Total with taxes and fees
Coastline Cottage with Breathtaking Ocean Views On Fripp Island Wi-Fi, Golf Cart

501 Sunsuite - Resort Access is included! Pet Friendly!

501 Sunsuite - Resort Access is included! Pet Friendly!
Fripp Island
9.8 out of 10, Exceptional, (11 reviews)
"This was a super getaway. From the friendly gate greeting, the comfortable, attractive room, the quick walk to the beach and everything for a wonderful 2 night stay! We hope to visit again!"
United States
Robbie
$332 nightly
The price is $365
Feb 27 - Feb 28
Total with taxes and fees
501 Sunsuite - Resort Access is included! Pet Friendly!

The Grey Pearl on Port Royal's Battery Creek

The Grey Pearl on Port Royal's Battery Creek
Beaufort
10.0 out of 10, Exceptional, (19 reviews)
"Great property "
United States
Caleb C.
$183 nightly
The price is $201
Feb 27 - Feb 28
Total with taxes and fees
The Grey Pearl on Port Royal's Battery Creek

Marriott's Barony Beach Club

Marriott's Barony Beach Club
3.5 star property
Mid Island
9.4 out of 10, Exceptional, (247 reviews)
"Great place for vacation on the beach, nice, clean and quiet areas "
United States
Larisa
$359 nightly
The price is $395
Feb 27 - Feb 28
Total with taxes and fees
Marriott's Barony Beach Club

A Room With a View-1 BR Efficiency Condo Close to Everything.

A Room With a View-1 BR Efficiency Condo Close to Everything.
Edisto Beach
9.8 out of 10, Exceptional, (132 reviews)
"Very clean and convenient place to stay. Check in and out were very easy. Communication with host was good!"
United States
Robert S.
$181 nightly
The price is $202
Mar 1 - Mar 2
Total with taxes and fees
A Room With a View-1 BR Efficiency Condo Close to Everything.

All Inn on Edisto - Cozy Studio Condo Close to Everything

All Inn on Edisto - Cozy Studio Condo Close to Everything
Edisto Beach
9.8 out of 10, Exceptional, (151 reviews)
"The property was nice and comfortable. Perfect for a couples get away. We only stayed one night, but were impressed by the property. "
United States
Stephen F.
$176 nightly
The price is $197
Feb 27 - Feb 28
Total with taxes and fees
All Inn on Edisto - Cozy Studio Condo Close to Everything

Marriott's Harbour Club

Marriott's Harbour Club
3.5 star property
Sea Pines
9.2 out of 10, Wonderful, (61 reviews)
"The staff was extremely inviting, professional, and kind. Parking was extremely easy we stayed in villa 3939. It was very large, clean, and had a great view. The property was conveniently located within the area and very walkable. It is very dark at night but we felt safe walking back from dinner. I’d definitely recommend this property for a quiet and peaceful getaway."
United States
ANGELEE
$295 nightly
The price is $325
Mar 4 - Mar 5
Total with taxes and fees
Marriott's Harbour Club

The Coral Pelican - 1 Block to Sand and Ocean!

The Coral Pelican - 1 Block to Sand and Ocean!
Fripp Island
9.8 out of 10, Exceptional, (22 reviews)
"Enjoyed our stay here. Kids and husband loved it and we all had a great time on fripp. Would rent again. "
United States
Neely T.
$612 nightly
The price is $673
Feb 27 - Feb 28
Total with taxes and fees
The Coral Pelican - 1 Block to Sand and Ocean!

Coastal Elegance. Poolside. Just steps from the beach! Cards available.

Coastal Elegance. Poolside. Just steps from the beach! Cards available.
Fripp Island
9.4 out of 10, Exceptional, (112 reviews)
"Great spot, close to the beach. "
United States
Eric D.
$289 nightly
The price is $318
Mar 1 - Mar 2
Total with taxes and fees
Coastal Elegance. Poolside. Just steps from the beach! Cards available.

Modern Coastal Escape on Beaufort's Battery Creek

Modern Coastal Escape on Beaufort's Battery Creek
Beaufort
9.8 out of 10, Exceptional, (34 reviews)
"Super cute condo, comfy accommodations super close to Parris Island. Way better than staying at a hotel."
United States
Kristine I.
$198 nightly
The price is $218
Feb 28 - Mar 1
Total with taxes and fees
Modern Coastal Escape on Beaufort's Battery Creek

Cozy Edisto Condo-Close to the Beach!

Cozy Edisto Condo-Close to the Beach!
Edisto Beach
9.0 out of 10, Wonderful, (87 reviews)
"Great place for our quick weekend get away! "
United States
Ronda J.
$165 nightly
The price is $185
Mar 1 - Mar 2
Total with taxes and fees
Cozy Edisto Condo-Close to the Beach!

Relax & Regroup at the Beach-Rock bottom February prices. Check them out!

Relax & Regroup at the Beach-Rock bottom February prices. Check them out!
Fripp Island
9.8 out of 10, Exceptional, (106 reviews)
"Great stay! "
United States
Jason c.
$325 nightly
The price is $357
Feb 27 - Feb 28
Total with taxes and fees
Relax & Regroup at the Beach-Rock bottom February prices. Check them out!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Top Ladys Island Hotel Reviews

Find out more about Ladys Island

Everything you need to know about Ladys Island vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Ladys Island vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Ladys Island vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Ladys Island vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Ladys Island. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Ladys Island in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $325 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Ladys Island rentals

At Expedia, we put the best Ladys Island vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Ladys Island rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Ladys Island vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Ladys Island. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.