A person paddleboarding on a calm sea with wind turbines in the background.

Santa Isabel Vacation Rentals

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Check prices for these dates

In two weeks
Sep 11 - Sep 13
In two months
Oct 23 - Oct 25
In three months
Nov 20 - Nov 22
In four months
Dec 18 - Dec 20

Our top choices for Santa Isabel vacation rentals

A beach with clear turquoise water, a sandy shore, and a rocky hill in the background.

1. Romantic 1BR Puerto Rico Villa w Pool|Aqua Bella 2

Romantic 1BR Puerto Rico Villa w Pool|Aqua Bella 2
Santa Isabel
10.0 out of 10, Exceptional, (3 reviews)
"We enjoyed our stay immensely. The bed was very comfortable. We loved the outdoor spaces. The parking was a little hard to figure out at first. We loved sitting by the water’s edge with morning coffee and evening glass of wine. "
United States
Penny O.
$530 nightly
The price is $562
Aug 30 - Aug 31
Total with taxes and fees
Romantic 1BR Puerto Rico Villa w Pool|Aqua Bella 2
A view through a window with a view of the sea and a small island.

2. Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep

Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep
Santa Isabel
8.8 out of 10, Excellent, (49 reviews)
"Host was very responsive to our texts"
United States
Arnie S.
$343 nightly
The price is $364
Aug 30 - Aug 31
Total with taxes and fees
Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep
A modern house with a pool, wooden deck, and outdoor seating area.

3. Coming and enjoy panoramic views to mountains and sea in Santa Isabel

Coming and enjoy panoramic views to mountains and sea in Santa Isabel
Santa Isabel
10.0 out of 10, Exceptional, (1 review)
"This is a unique property with beautiful views. The hosts were incredibly helpful and responsive!"
United States
Annie H.
$319 nightly
The price is $339
Aug 31 - Sep 1
Total with taxes and fees
Coming and enjoy panoramic views to mountains and sea in Santa Isabel
A rooftop terrace with a red pool, string lights, and a hanging chair.

4. Home in Santa Isabel, Puerto Rico. 4BR 2BA home with WiFi, AC & UNDERGROUND POOL

Home in Santa Isabel, Puerto Rico. 4BR 2BA home with WiFi, AC & UNDERGROUND POOL
Santa Isabel
10.0 out of 10, Exceptional, (5 reviews)
"Great host communication, central location, lovely home. "
United States
Scott P.
$499 nightly
The price is $530
Sep 3 - Sep 4
Total with taxes and fees
Home in Santa Isabel, Puerto Rico. 4BR 2BA home with WiFi, AC & UNDERGROUND POOL
A compact RV kitchen with wooden cabinets, a built-in TV, a small dining area, and a sink.

5. La Gozadera Park

La Gozadera Park
1.0 star property
Salinas
10.0 out of 10, Exceptional, (2 reviews)
$112 nightly
The price is $122
Aug 30 - Aug 31
Total with taxes and fees
La Gozadera Park
An outdoor seating area with wicker furniture, a table with a bottle, and a view of the sea.

6. The Place at the Sea

The Place at the Sea
3.0 star property
Ponce
9.4 out of 10, Exceptional, (426 reviews)
"Recommended Excellent place, Personnel keep place very Clean and they care about hosts. Air Conditions works great."
United States
Luis
$54 nightly
The price is $59
Sep 29 - Sep 30
Total with taxes and fees
The Place at the Sea
A bedroom with a bed, a desk with a computer, and a wardrobe.

7. Ponce Pueblo Central Apt

Ponce Pueblo Central Apt
Ponce Centro
5.6 out of 10, (4 reviews)
"Too small. No microwave. Bed and futon too low. No tv in the living room. Etc."
United States
Kenneth R.
$111 nightly
The price is $117
Aug 30 - Aug 31
Total with taxes and fees
Ponce Pueblo Central Apt
An outdoor patio area with wicker furniture and a stone floor, surrounded by lush greenery and trees.

8. Oasis Salinas

Oasis Salinas
Salinas
8.0 out of 10, Very Good, (14 reviews)
"Excellent place to stay near everything in town "
United States
Mayra
$130 nightly
The price is $138
Aug 30 - Aug 31
Total with taxes and fees
Oasis Salinas
A cozy living room with a wooden ceiling, a sofa, a wicker chair, and a flag on the door.

9. A cozy place to stay walking distance from the beach and Restaurants.

A cozy place to stay walking distance from the beach and Restaurants.
Salinas
9.4 out of 10, Exceptional, (27 reviews)
"Complete kitchen, fairly quiet area, near great restaurants "
United States
John W.
$133 nightly
The price is $141
Sep 2 - Sep 3
Total with taxes and fees
A cozy place to stay walking distance from the beach and Restaurants.

10. Enjoyable 2nd story, 3-bedroom house with AC in Coamo, PR

Enjoyable 2nd story, 3-bedroom house with AC in Coamo, PR
Coamo
7.0 out of 10, Good, (2 reviews)
"Spotless cozy , ice cold air"
United States
Alberto
$140 nightly
The price is $148
Aug 30 - Aug 31
Total with taxes and fees
Enjoyable 2nd story, 3-bedroom house with AC in Coamo, PR
A modern living room with white furniture, a large mirror, and artwork on the wall.

11. Aibonito Hotel 208

Aibonito Hotel 208
2.5 star property
Aibonito
6.0 out of 10, (11 reviews)
"It was surprisingly a cute place "
United States
Jesus Manuel
$80 nightly
The price is $86
Aug 31 - Sep 1
Total with taxes and fees
Aibonito Hotel 208
A beach with boats docked in calm waters, a clear sky, and a sandy shore.

12. House Salinas (WIFI) - The best part of your getaway

House Salinas (WIFI) - The best part of your getaway
Salinas
9.8 out of 10, Exceptional, (24 reviews)
"Nice cozy home near downtiwn, Salinas PR"
United States
Kenneth C.
$228 nightly
The price is $242
Aug 31 - Sep 1
Total with taxes and fees
House Salinas (WIFI) - The best part of your getaway
A wooden deck with a welcome mat and potted plants.

13. Nostra Casa Vagón

Nostra Casa Vagón
Coamo
10.0 out of 10, Exceptional, (1 review)
"Everything was very clean and organized I got confused with the address and the owner communicated with me and directed me to the exact address when I go to Puerto Rico again I will contact them again to stay at the same place "
United States
Carlos Reyes
$140 nightly
The price is $148
Aug 30 - Aug 31
Total with taxes and fees
Nostra Casa Vagón
A modern two-story house with a garage, surrounded by palm trees and a clear sky.

14. Anime Escape with Private Jacuzzi & Themed Rooms

Anime Escape with Private Jacuzzi & Themed Rooms
San Ildefonso
8.8 out of 10, Excellent, (3 reviews)
"We had a blast! "
United States
Keyla F.
$290 nightly
The price is $308
Aug 30 - Aug 31
Total with taxes and fees
Anime Escape with Private Jacuzzi & Themed Rooms
A modern bedroom with a bed, bedside table, and a TV mounted on the wall.

15. Aibonito Hotel 205

Aibonito Hotel 205
3.0 star property
Aibonito
7.6 out of 10, Good, (28 reviews)
"It's a great location and convenient to another locations. Staff was was friendly and helpful. I ended up booking additional room for family."
United States
Christine
$81 nightly
The price is $86
Aug 31 - Sep 1
Total with taxes and fees
Aibonito Hotel 205
A wooden dresser with a potted plant on top, a mirror above it, and a decorative piece on the dresser.

16. Trinitarias Guest's House's pool/bar/karaoke/wifi

Trinitarias Guest's House's pool/bar/karaoke/wifi
Salinas
9.0 out of 10, Wonderful, (4 reviews)
"Felt like home beautiful super clean quiet I will definitely be back to this home in our vacations Host is amazing Thank You for sharing this beautiful house with my family "
United States
julio
$188 nightly
The price is $199
Aug 31 - Sep 1
Total with taxes and fees
Trinitarias Guest's House's pool/bar/karaoke/wifi
A bedroom with a bed, a TV mounted on the wall, a window with blinds, and a shelf with items.

17. Casa Ponceña Ponce Pueblo

Casa Ponceña Ponce Pueblo
Ponce Centro
6.0 out of 10, (4 reviews)
"The area where the property is located is unsafe. No place to park our car."
United States
Yeiza
$111 nightly
The price is $117
Aug 30 - Aug 31
Total with taxes and fees
Casa Ponceña Ponce Pueblo
A beach scene with the sun setting over the water, palm trees, and a distant shoreline.

18. Family house with Sea View

Family house with Sea View
arroyo
9.6 out of 10, Exceptional, (5 reviews)
"Place was super nice loved the beach view"
United States
Cynthia
$120 nightly
The price is $126
Aug 31 - Sep 1
Total with taxes and fees
Family house with Sea View
An aerial view of a small island with clear turquoise waters, a sandy beach, and a few structures.

19. Charming Retreat with Patio Access and Laundry

Charming Retreat with Patio Access and Laundry
Ponce
8.8 out of 10, Excellent, (24 reviews)
"Clean place, good communication with host, pleasant stay. Comfy beds, nice A/C. Nice neighborhood. Only issue, was the bathroom which had a musty odor all the time. "
United States
Jorge A T.
$153 nightly
The price is $163
Aug 30 - Aug 31
Total with taxes and fees
Charming Retreat with Patio Access and Laundry
An aerial view of a small island with clear turquoise waters, a sandy beach, and a few structures.

20. Private Patio Retreat with Zen Vibe and Laundry

Private Patio Retreat with Zen Vibe and Laundry
Ponce
9.4 out of 10, Exceptional, (16 reviews)
"Was great quiet, clean and very safe, we felt confortable and the neighbors were very friendly "
United States
Magda R.
$137 nightly
The price is $145
Aug 31 - Sep 1
Total with taxes and fees
Private Patio Retreat with Zen Vibe and Laundry
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Isabel Hotel Reviews

Spark by Hilton Ponce

Spark by Hilton Ponce

10/10 Excellent
"Excelent"
Samary 2-night trip
Posted 1 hour ago
Spark by Hilton Ponce

Find out more about Santa Isabel

Everything you need to know about Santa Isabel vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Isabel vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Isabel vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santa Isabel vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Isabel. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santa Isabel in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $59 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santa Isabel rentals

At Expedia, we put the best Santa Isabel vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santa Isabel rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Isabel vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Isabel. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Are there vacation rentals in Santa Isabel?

Yes, there are vacation rentals close to the most popular attractions in Santa Isabel, or you can choose a secluded option if you're looking for relaxation. Santa Isabel is known for its shopping and restaurants. Make sure you have time to check out the beaches while you're in the area.

What's the top vacation rental that Santa Isabel has to offer?

3BR Puerto Rico Villa w Pool | Aqua Bella 1: This highly rated vacation home rental in Santa Isabel is located by the ocean and has a balcony, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. Make the most of the selection of games in this rental home to help you unwind. Our travelers also rate Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep as a favorite home for rent in Santa Isabel.

How many vacation rentals will I find in Santa Isabel?

Expedia has 7 vacation rentals for your stay in Santa Isabel.

What can I see and do in Santa Isabel?

Explore the area and family-friendly sights such as Museo de la Musica Puertorriquena, or get out into nature at a spot like Coamo Springs. Carribbean Cinemas Santa Isabel and Marina de Salinas are a couple of places you'll find in the larger area.

What are vacation rentals like in Santa Isabel?

Vacation rentals are privately owned properties you can reserve for a couple days or more in Santa Isabel. Vacation rentals offer extras like WiFi and washers and dryers so you'll be comfy for your stay. If you're concerned about cleanliness, vacation rentals can provide a sense of safety away from shared hotel elevators and busy lobbies while still allowing you the experience of travel. You'll also find more space in a vacation rental than in a standard hotel, which makes a vacation rental a popular option for a family trip.