Santee Vacations from $326

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Your Santee Vacation

Enjoy unforgettable adventures when you book a vacation package to Santee. Whether you're a foodie, art buff or just a traveler who loves discovering new places, there's something for everyone in this lively city. If your trip to Santee includes some sightseeing, don't miss famous attractions like Santee State Park, Santee Cooper Country Club and Santee Outlets. Stop daydreaming and start traveling. Browse the many options on Expedia today and put your Santee vacation plans into action!

The Latest Santee vacation packages

Price found within the past 48 hours. Click for updated prices.
Baymont by Wyndham Columbia Northwest

Baymont by Wyndham Columbia Northwest

2.5 out of 5
per person
Sep 26 - Oct 1
found 1 day ago
Roundtrip flight included
New York (NYC) to Columbia (CAE)
5.4/10 (1,002 reviews)
Always liked coming here. Clean comfortable and great price

Reviewed on Jun 29, 2025

Staybridge Suites Columbia by IHG

Staybridge Suites Columbia by IHG

3 out of 5
Downtown Columbia
per person
Oct 3 - Oct 7
found 22 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Columbia (CAE)
9.2/10 Wonderful! (955 reviews)
Nice environment lovely staff would book again!

Reviewed on Jun 22, 2025

Days Inn & Suites by Wyndham Columbia Airport

Days Inn & Suites by Wyndham Columbia Airport

2 out of 5
per person
Oct 3 - Oct 7
found 22 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Columbia (CAE)
5.8/10 (729 reviews)
TV had something wrong with the display.

Reviewed on Feb 20, 2025

Microtel Inn & Suites by Wyndham Columbia/At Fort Jackson

Microtel Inn & Suites by Wyndham Columbia/At Fort Jackson

2 out of 5
per person
Oct 3 - Oct 7
found 22 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Columbia (CAE)
7.4/10 Good! (1,001 reviews)
The bathroom very small , floor get wet from the face basin , if I was a plus side I wouldn’t fit in shower .Breakfast options are terrible. The front desk staff and room service crew are very kind and helpful.

Reviewed on Jun 14, 2025

Hotel Trundle

Hotel Trundle

3 out of 5
Downtown Columbia
per person
Oct 3 - Oct 7
found 22 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Columbia (CAE)
9.8/10 Exceptional! (911 reviews)
Cute Boutique style hotel with great decor. Super attentive staff that made everything perfect throughout our stay. Will definitely stay again.

Reviewed on Jun 23, 2025

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Discover the most popular places to visit in Santee

Santee State Park

4/5(43 reviews)

You can take time to visit Santee State Park during your travels to Santee. While you're here, you can savor the top-notch restaurants.

Santee State Park

Santee Cooper Country Club

4/5(12 reviews)

Enjoy a round of golf in Santee at Santee Cooper Country Club. While you're here, you can savor the top-notch restaurants.

Santee Cooper Country Club

Santee National Golf Club

3.5/5(19 reviews)

Enjoy a round of golf in Santee at Santee National Golf Club. While you're here, you can savor the top-notch restaurants.

Santee National Golf Club

Santee Hotel Deals

Baymont by Wyndham Santee
Baymont by Wyndham Santee
2.5 out of 5
249 Britain Street, Santee, SC
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $83 total per night from Jul 13 to Jul 14
$83 total
Jul 13 - Jul 14
Total includes taxes and fees
7.8/10 Good! (1,310 reviews)
"Well maintained motel. Friendly staff. Includes a Continental breakfast. Great value for the money."

Reviewed on Jul 9, 2025

Baymont by Wyndham Santee
Fairfield Inn & Suites by Marriott Santee
Fairfield Inn & Suites by Marriott Santee
2.5 out of 5
9074 Old Number Six Hwy, Santee, SC
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $144 total per night from Jul 20 to Jul 21
$144 total
Jul 20 - Jul 21
Total includes taxes and fees
9.8/10 Exceptional! (1,000 reviews)
"Wry clean and easy"

Reviewed on Jul 8, 2025

Fairfield Inn & Suites by Marriott Santee
Tru By Hilton Santee
Tru By Hilton Santee
2.5 out of 5
263 Britain St. and 273 Britain St., Santee, SC
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $112 total per night from Jul 20 to Jul 21
$112 total
Jul 20 - Jul 21
Total includes taxes and fees
9/10 Wonderful! (472 reviews)
Great little hotel.
"Hotel was clean, cute style lobby and rooms. Breakfast was good beds were comfy, but pillows were not good. I would only wish that they gave a complimentary bottled water like Marriott does. Just my preference.There were a couple of good places to eat. Our favorite Captains Quarters was closed Mondays ..."

Reviewed on Jul 9, 2025

Tru By Hilton Santee
See all 284 properties in Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santee Vacation Packages

Santee Essential Information

Language
English
Currency
U.S dollars
Population
940
Max Temp Winter
55ºF
Max Temp Summer
90ºF
Top Sights
Santee State Park, Santee Cooper Country Club and Santee National Golf Club

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Frequently asked questions

How much does a Santee vacation package cost?
Offering excellent value package deals from $326 on Expedia, you'll be surprised at how little a vacation to Santee costs! Our packages make travel planning easier and your savings go further.
What are the cheapest months to go to Santee?
If you're hoping to snag a cheap Santee vacation package, consider visiting in January, September and October. You're likely to find better prices on accommodations and flights during these quieter months --- ideal for budget-conscious travelers.
How many days is enough for Santee?
The ideal length for your Santee vacation depends on what you'd like to see and do. Usually, a few days to a week will give you time to hit all the leading attractions and explore some hidden treasures along the way.
Is it worth booking a vacation package to Santee?
It's no wonder a Santee vacation is on the to-do list of many travelers. Major attractions like Santee State Park are just the beginning of things to see and do here.
How to find the best Santee package deals?
Use Expedia's handy filters to help you find some fabulous Santee package deals. When you begin your search, simply set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your break for midweek, or search for Santee package deals in the low season. Switch up your travel dates and you may land even better discounts. As a rule of thumb, it's typically best to lock in your vacation package as early as possible.
Is it cheaper to book a Santee vacation as a package?
An Expedia vacation package could land you considerable savings when compared to booking stays and flights individually. Better still, you can customize your Santee trip to match your exact needs. Pick your preferred flight time, select the hotel type and add a rental car. Browse our great deals to see how much you can save.
When to book a vacation package to Santee?
If you have your Santee vacation dates locked in, book as soon as you can to score some incredible deals. With Expedia, you can generally reserve some flights up to one year ahead of time. Prefer spur-of-the-moment adventures? Our last-minute deals are perfect for quick escapes.
Does Expedia offer Book Now, Pay Later Santee vacation packages?
If you're anything like us, you love discovering new places but don't love the price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With help from online lender Affirm, you can spread the total cost of your Santee trip across 3, 6 or 12 months. There are also no late payment fees or hidden costs, so you can snap up cheap vacation packages with payment plans as soon as you spot them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.