Find 5 Star Hotels in South Boston, MA from $125

Start date: Check-in selected.
To Date
End date: Check-out
  • Upfront pricing

    Our total price for your stay includes taxes and fees
  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
  • Be picky

    Search almost a million properties worldwide

Check availability on South Boston 5 Star Hotels

This weekend
Next weekend

Compare South Boston 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Omni Boston Hotel at the Seaport

5.0 star property
Seaport District
9.2 out of 10, Wonderful, (4285)
"beautiful hotel "
United States
stacy
$174 nightly
The price is $203
Dec 14 - Dec 15
Total with taxes and fees
Omni Boston Hotel at the Seaport

The Langham, Boston

5.0 star property
Downtown Boston
9.6 out of 10, Exceptional, (1000)
"Great hotel"
United Kingdom
Caren Christina
$365 nightly
The price is $425
Jan 1 - Jan 2, 2026
Total with taxes and fees
The Langham, Boston

The Newbury Boston

5.0 star property
Back Bay
9.4 out of 10, Exceptional, (542)
"Excellent hotel. "
United Kingdom
Anne
$494 nightly
The price is $575
Dec 15 - Dec 16
Total with taxes and fees
The Newbury Boston

Four Seasons Hotel Boston

5.0 star property
Bay Village
9.4 out of 10, Exceptional, (450)
"Amazing staff and lovely hotel in general "
United Kingdom
Sharon Mary
$750 nightly
The price is $873
Dec 12 - Dec 13
Total with taxes and fees
Four Seasons Hotel Boston

InterContinental Boston by IHG

5.0 star property
Downtown Boston
9.4 out of 10, Exceptional, (1002)
"Beautiful hotel, great location, gracious staff."
United States
Amalia
$167 nightly
The price is $195
Dec 22 - Dec 23
Total with taxes and fees
InterContinental Boston by IHG

Boston Harbor Hotel

5.0 star property
North End
9.8 out of 10, Exceptional, (1002)
"Great hotel. "
United States
Brian
$484 nightly
The price is $563
Jan 4 - Jan 5, 2026
Total with taxes and fees
Boston Harbor Hotel

Mandarin Oriental, Boston

5.0 star property
Back Bay
9.4 out of 10, Exceptional, (382)
"Excellent stay. Most perfect location in Boston. "
United States
Niki
$476 nightly
The price is $554
Jan 4 - Jan 5, 2026
Total with taxes and fees
Mandarin Oriental, Boston

Four Seasons Hotel One Dalton Street, Boston

5.0 star property
Back Bay
9.6 out of 10, Exceptional, (367)
"The staff were consistently warm and attentive, and the property offered high-end, well-maintained amenities throughout my stay. "
United States
Sihao
$560 nightly
The price is $652
Dec 18 - Dec 19
Total with taxes and fees
Four Seasons Hotel One Dalton Street, Boston

The Liberty, a Marriott Luxury Collection Hotel, Boston

5.0 star property
West End
8.8 out of 10, Excellent, (1005)
"Gorgeous hotel. Lots of history and "
Canada
Jenny
$220 nightly
The price is $256
Dec 28 - Dec 29
Total with taxes and fees
The Liberty, a Marriott Luxury Collection Hotel, Boston

The Ritz-Carlton, Boston

5.0 star property
Downtown Boston
9.0 out of 10, Wonderful, (414)
"Exceptional staff, clean and well appointed room"
United States
JOHN
$499 nightly
The price is $581
Dec 12 - Dec 13
Total with taxes and fees
The Ritz-Carlton, Boston

Raffles Boston

5.0 star property
Back Bay
9.6 out of 10, Exceptional, (189)
"Loved everything about our stay, food, pool and ambiance all incredible. Will stay again!"
United States
Don
$595 nightly
The price is $693
Dec 20 - Dec 21
Total with taxes and fees
Raffles Boston

XV Beacon

5.0 star property
Beacon Hill
9.4 out of 10, Exceptional, (384)
"I had a wonderful experience at the XV Beacon Hotel. The room and bathroom was modern and updated. I also thought the gym was clean."
United States
Jana
$581 nightly
The price is $676
Dec 5 - Dec 6
Total with taxes and fees
XV Beacon
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in South Boston.
Still don't see what you're looking for?
See all properties in South Boston.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about South Boston

No other place says Boston better than this neighborhood, where the accents are authentic and history is still present around every corner.

Institute of Contemporary Art which includes modern architecture and night scenes

Top South Boston Hotel Reviews

Find out more about South Boston

There's nothing wrong with enjoying the finer things in life. Add an extra layer of luxury on your next trip to South Boston by treating yourself to the best of the best when it comes to accommodation. It's an ideal pairing. There's no reason to delay a getaway to South Boston any longer. You'll join the multitudes of vacationers who have made South Boston so fashionable in the last year. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. You deserve the great vacation you're dreaming about. Our 5-star hotels in South Boston are the perfect places to relax in when you really need to escape.

Book the Best South Boston 5-Star Hotels

You'll have a fantastic time at one of these 5-star hotels. High-end restaurants, concierges, and pillow-fluffing are all at the ready. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. How do you want to relax? A deep-tissue massage to help your cares fall away? A concierge to help you make reservations at that outstanding restaurant? High thread-count sheets, lip-smacking main courses, and even a hot tub in the bathroom...these hotels will leave you amazed. Want to see for yourself? Explore our listings and pick the perfect accommodation for your needs.

Yearning for experiences outside your hotel room? We hear you. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. Whatever you plan to do, the 5-star hotels in South Boston are waiting for you to relax after an exciting day.

Your Getaway Starts Today

The results are in, and South Boston 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Your great getaway is just a mouse-click away -- Expedia can help you land a great deal on accommodation. Opt for one of our South Boston 5-star hotels today and settle down in total tranquility when you're ready.

Frequently asked questions

What are the best 5-star hotels in South Boston?
InterContinental Boston, an IHG Hotel is among the best picks around the Boston neighborhood of South Boston according to reviews by Expedia customers. The Ritz-Carlton, Boston and Boston Harbor Hotel are other 5-star hotels in this area that rate highly with travelers.
How much does it cost to stay in a 5-star hotel in South Boston?
How much you pay for a 5-star hotel in South Boston depends on things like when you want to go and the length of your vacation. A top tip for scoring the best deal? Use our pricing filters to check out all of the available hotels for your selected dates.

  • Search for the lowest price per night from $125

What makes a hotel 5 stars in South Boston?
In South Boston, a hotel is required to offer a specific amount of upscale amenities to be designated 5 stars. These may include on-site gyms, gourmet restaurants, saunas and spas, premium bedding, complimentary luxury toiletries and more. What also sets 5-star hotels apart is their guest-focused service. You can look forward to things like nightly turn-down services, in-room massages and concierge services. Some may even offer extra touches like a welcome gift.

Explore a world of travel with Expedia