Find hotels in Mayo Clinic, Phoenix

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Discover Mayo Clinic hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Lobby lounge
Sonesta Select Scottsdale at Mayo Clinic Campus

Sonesta Select Scottsdale at Mayo Clinic Campus

3.0 star property
Mayo Clinic
8.2 out of 10, Very Good, (1043)
"Very clean and very friendly staff "
United States
Michelle
$101 nightly
The price is $115
Dec 2 - Dec 3
Total with taxes and fees
Sonesta Select Scottsdale at Mayo Clinic Campus
Gazebo
La Quinta Inn & Suites by Wyndham Mesa Superstition Springs

La Quinta Inn & Suites by Wyndham Mesa Superstition Springs

3.0 star property
15 mi from Mayo Clinic
8.2 out of 10, Very Good, (1796)
"Enjoyed our stay!"
United States
Alejandra
$80 nightly
The price is $92
Dec 16 - Dec 17
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Mesa Superstition Springs
Outdoor pool, open 7 AM to 10 PM, free cabanas, pool umbrellas
Holiday Inn Express & Suites Phoenix East - Gilbert by IHG

Holiday Inn Express & Suites Phoenix East - Gilbert by IHG

2.5 star property
14.9 mi from Mayo Clinic
9.4 out of 10, Exceptional, (1006)
"Cleanest hotel room we have had in quite a while, very courteous desk staff, very nice breakfast choices. "
United States
Connie
$118 nightly
The price is $135
Dec 18 - Dec 19
Total with taxes and fees
Holiday Inn Express & Suites Phoenix East - Gilbert by IHG
Room, 2 Queen Beds, Accessible, Non Smoking | Pillowtop beds, in-room safe, desk, iron/ironing board
Days Inn & Suites by Wyndham Mesa Near Phoenix

Days Inn & Suites by Wyndham Mesa Near Phoenix

3.0 star property
14.3 mi from Mayo Clinic
9.0 out of 10, Wonderful, (2046)
"Clean room, professional staff, great breakfast selection. "
United States
Harmony
$80 nightly
The price is $92
Dec 2 - Dec 3
Total with taxes and fees
Days Inn & Suites by Wyndham Mesa Near Phoenix
Exterior
Best Western North Phoenix Hotel

Best Western North Phoenix Hotel

2.5 star property
18.6 mi from Mayo Clinic
8.8 out of 10, Excellent, (1016)
"Great location "
United States
Linda
$97 nightly
The price is $110
Dec 15 - Dec 16
Total with taxes and fees
Best Western North Phoenix Hotel
Exterior
SureStay Plus by Best Western Mesa Superstition Springs

SureStay Plus by Best Western Mesa Superstition Springs

2.5 star property
14.5 mi from Mayo Clinic
8.4 out of 10, Very Good, (1649)
"Great stay"
United States
Niel
$75 nightly
The price is $86
Dec 2 - Dec 3
Total with taxes and fees
SureStay Plus by Best Western Mesa Superstition Springs
Exterior
Hilton Phoenix Tapatio Cliffs Resort

Hilton Phoenix Tapatio Cliffs Resort

4.0 star property
15.8 mi from Mayo Clinic
8.6 out of 10, Excellent, (2210)
"Had a nice stay at this hotel. Lovely restaurant and beautiful view for cocktails. "
United States
Bob
$145 nightly
The price is $164
Dec 21 - Dec 22
Total with taxes and fees
Hilton Phoenix Tapatio Cliffs Resort
Lobby
Country Inn & Suites by Radisson, Mesa, AZ

Country Inn & Suites by Radisson, Mesa, AZ

2.5 star property
15.1 mi from Mayo Clinic
7.8 out of 10, Good, (1013)
"Great staff"
United States
Tracy
$88 nightly
The price is $101
Dec 28 - Dec 29
Total with taxes and fees
Country Inn & Suites by Radisson, Mesa, AZ
Reception
The Azure Hotel

The Azure Hotel

2.5 star property
11.9 mi from Mayo Clinic
8.8 out of 10, Excellent, (1622)
"The room was clean, grounds were well maintained, location was a bit isolated, breakfast could use more hot foods like eggs and sausage, staff was courteous. I would stay there again."
United States
Johanna
$83 nightly
The price is $95
Dec 2 - Dec 3
Total with taxes and fees
The Azure Hotel
Terrace/patio
Wekopa Casino Resort

Wekopa Casino Resort

4.0 star property
6.3 mi from Mayo Clinic
9.2 out of 10, Wonderful, (1014)
"Great stay"
Canada
Joel Edward
$188 nightly
The price is $210
Dec 2 - Dec 3
Total with taxes and fees
Wekopa Casino Resort
Lobby sitting area
Sentral Sol Modern

Sentral Sol Modern

2.0 star property
18.6 mi from Mayo Clinic
9.4 out of 10, Exceptional, (97)
"Great place to stay will be back! "
United States
Keah
$133 nightly
The price is $151
Dec 28 - Dec 29
Total with taxes and fees
Sentral Sol Modern
Tapas bar
AC Hotel by Marriott Phoenix Biltmore

AC Hotel by Marriott Phoenix Biltmore

4.0 star property
14.2 mi from Mayo Clinic
9.4 out of 10, Exceptional, (663)
"Great hotel!"
United States
Richard
$135 nightly
The price is $153
Dec 21 - Dec 22
Total with taxes and fees
AC Hotel by Marriott Phoenix Biltmore
2 restaurants, breakfast, lunch, dinner served; American cuisine
Hyatt Regency Phoenix

Hyatt Regency Phoenix

4.0 star property
18.6 mi from Mayo Clinic
9.2 out of 10, Wonderful, (1873)
"First class service, wonderful room that was spotless and comfortable, great location, all in all excellent."
United Kingdom
Jacqueline
$184 nightly
The price is $208
Dec 8 - Dec 9
Total with taxes and fees
Hyatt Regency Phoenix
Exterior
Hilton Garden Inn Scottsdale Old Town

Hilton Garden Inn Scottsdale Old Town

3.0 star property
Brown and Stetson Business, 9.8 mi from Mayo Clinic
9.0 out of 10, Wonderful, (1016)
"Very nice rooms with very nice and helpful staff. Even got late checkout and the pool area was great!"
United States
Grace
$103 nightly
The price is $118
Dec 19 - Dec 20
Total with taxes and fees
Hilton Garden Inn Scottsdale Old Town
Lobby
Comfort Suites Scottsdale Talking Stick Entertainment District

Comfort Suites Scottsdale Talking Stick Entertainment District

2.5 star property
6 mi from Mayo Clinic
9.2 out of 10, Wonderful, (1758)
"Clean rooms, nice location, great value."
United States
Robert
$89 nightly
The price is $102
Dec 28 - Dec 29
Total with taxes and fees
Comfort Suites Scottsdale Talking Stick Entertainment District
Balcony
FOUNDRE Phoenix

FOUNDRE Phoenix

4.0 star property
18.4 mi from Mayo Clinic
9.2 out of 10, Wonderful, (2209)
"The hotel is beautiful and the food is great at the restaurant."
United States
JodiAnn
$132 nightly
The price is $149
Dec 21 - Dec 22
Total with taxes and fees
FOUNDRE Phoenix
Exterior
Hampton Inn & Suites Phoenix Downtown

Hampton Inn & Suites Phoenix Downtown

3.0 star property
18.6 mi from Mayo Clinic
9.2 out of 10, Wonderful, (1679)
"Great place to stay! "
United States
Crayton
$104 nightly
The price is $118
Dec 14 - Dec 15
Total with taxes and fees
Hampton Inn & Suites Phoenix Downtown
Terrace/patio
Hampton Inn by Hilton Carefree

Hampton Inn by Hilton Carefree

2.5 star property
18.1 mi from Mayo Clinic
9.4 out of 10, Exceptional, (591)
"Clean,quiet,great location and great employees "
United States
Robert
$110 nightly
The price is $125
Dec 10 - Dec 11
Total with taxes and fees
Hampton Inn by Hilton Carefree
Courtyard
Papago Scottsdale by Reside, Trademark Collection by Wyndham

Papago Scottsdale by Reside, Trademark Collection by Wyndham

3.0 star property
11.5 mi from Mayo Clinic
8.6 out of 10, Excellent, (245)
"I had a good stay there "
United States
Arben
$88 nightly
The price is $100
Dec 22 - Dec 23
Total with taxes and fees
Papago Scottsdale by Reside, Trademark Collection by Wyndham
Exterior
Staybridge Suites Phoenix East - Gilbert by IHG

Staybridge Suites Phoenix East - Gilbert by IHG

3.0 star property
14.9 mi from Mayo Clinic
9.6 out of 10, Exceptional, (851)
"Great stay!"
United States
Matthew
$125 nightly
The price is $143
Dec 25 - Dec 26
Total with taxes and fees
Staybridge Suites Phoenix East - Gilbert by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Mayo Clinic

Find the best Mayo Clinic areas and neighborhoods for the activities you enjoy most.
Downtown Phoenix which includes signage and night scenes

Downtown Phoenix

A true urban neighborhood, Downtown Phoenix boasts major sports venues like Chase Field and Footprint Center, as well as cultural attractions such as the Arizona Science Center and Phoenix Art Museum. Easily accessible via Valley Metro Light Rail, enjoy walkable streets, friendly cafes, and local businesses.

Old Town

Old Town

Old Town is known for its popular shops, and you can see some sights in the area like Western Spirit: Scottsdale's Museum of the West and Fiesta Bowl Museum.

Papago Park featuring desert views as well as a small group of people

Camelback East

Adjacent to Paradise Valley and Scottsdale, Camelback East Village boasts two main cores and sits between Piestewa Peak and Camelback Mountain. Explore the vibrant 24th Street and Camelback Road or 44th Street and Van Buren Street areas.

East Mesa

While you're in East Mesa, take in top sights like Salt River Tubing and jump on the metro at Superstition Springs Transit Center to see more of the city.

Central Scottsdale

While visiting Central Scottsdale, you might make a stop by sights like Scottsdale Ranch Park and Starfire Golf Club at Scottsdale Country Club.

Top Mayo Clinic Hotel Reviews

Scottsdale Camelback Resort

Scottsdale Camelback Resort

10/10 Excellent
"clean quiet and kitchen fully equipped just need body cream to make it perfect "
ELAINE 5-night trip
Posted 11 hours ago
Scottsdale Camelback Resort

Frequently asked questions

What are the best hotels in Mayo Clinic that travelers recommend?
Sonesta Select Scottsdale at Mayo Clinic Campus is a highly regarded hotel, receiving a great rating of 8.2 from guests. This property is not only conveniently located near the renowned Mayo Clinic, but it also boasts a range of amenities designed for both relaxation and productivity. Families and business travelers alike can enjoy the outdoor pool, hot tub, and comfortable meeting rooms, making it easy to unwind after a busy day or conduct successful meetings in a serene environment.
What are the best family hotels in Mayo Clinic?
Sonesta Select Scottsdale at Mayo Clinic Campus is an excellent choice for families visiting the area, boasting an excellent review score of 8.2. This property features connecting rooms, allowing families to stay close together while enjoying their own space, which is particularly beneficial for those with children.
What are the best budget hotels in Mayo Clinic?
Sonesta Select Scottsdale at Mayo Clinic Campus is a fantastic option for budget travelers seeking comfort and convenience. This hotel offers a warm and friendly setting, along with an impressive array of amenities to enhance your stay. Guests appreciate the free Wi-Fi throughout the property, making it easy to stay connected, and the outdoor pool and hot tub provide a superb spot to unwind after a day of exploring.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Mayo Clinic.
How can I save on a Mayo Clinic hotel booking with Expedia?
One Key™ - Expedia's free travel rewards program - gives you instant access to perks and Member Prices on Mayo Clinic hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings.

*OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Mayo Clinic hotel?
Hotel prices in Mayo Clinic often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

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