Ladys Island Vacation Rentals from $329: Search Short-Term Rentals

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Our top choices for Ladys Island vacation rentals

Sand In My Boots, Minutes to Parris Island & Beaufort and the beach!

Beaufort

Patrick G.

$397 nightly

Apr 18 - Apr 19

Total with taxes and fees

Relax under the Shade of a Live Oak! MCRD Paris Island and MCAS 10 Minute Drive

Beaufort

Jasminee L.

$401 nightly

Apr 7 - Apr 8

Total with taxes and fees

Amazing Airstream, Beaufort, SC-Enjoy the Journey!

Beaufort

Nate P.

$159 nightly

Apr 7 - Apr 8

Total with taxes and fees

501 Sunsuite

Fripp Island

Robbie

$367 nightly

Apr 13 - Apr 14

Total with taxes and fees

Tranquility by the Beach 1st Fl Sleeps 6,King Bed

Mid Island

A. D.

$269 nightly

Apr 12 - Apr 13

Total with taxes and fees

Ocean Front & pool view. Hunting Island pass included

Beachwalk

Greg B.

$360 nightly

Apr 7 - Apr 8

Total with taxes and fees

All Inn on Edisto - Cozy Studio Condo Close to Everything

Edisto Beach

Cabell G.

$174 nightly

Apr 12 - Apr 13

Total with taxes and fees

Cozy Edisto Condo-Close to the Beach!

Edisto Beach

Ronda J.

$165 nightly

Apr 14 - Apr 15

Total with taxes and fees

Gorgeous Waterfront Battery Creek Retreat

Beaufort

Jad

$198 nightly

Apr 12 - Apr 13

Total with taxes and fees

The Grey Pearl on Port Royal's Battery Creek

Beaufort

Caleb C.

$198 nightly

Apr 13 - Apr 14

Total with taxes and fees

Mariners' Nautical Nest on Port Royal's Battery Creek

Beaufort

Glenn G.

$185 nightly

Apr 7 - Apr 8

Total with taxes and fees

'wright by the Beach': Hilton Head Condo w/ Perks

Mid Island

Victor

$249 nightly

Apr 13 - Apr 14

Total with taxes and fees

Frippin Fun Vacation - Fripp Island

Saint Helena Island

Amy C.

$319 nightly

May 1 - May 2

Total with taxes and fees

Coastal Elegance. Poolside. Just steps from the beach! Cards available.

Fripp Island

Eric D.

$324 nightly

Apr 13 - Apr 14

Total with taxes and fees

Newly Renovated, Spacious 2bd Apartment w. Parking!

Historic District

Debby

$308 nightly

Apr 8 - Apr 9

Total with taxes and fees

King Suite at The Emerald, Spa Bathroom w. Robes!

Historic District

Leah R.

$183 nightly

Apr 15 - Apr 16

Total with taxes and fees

Relax on Huge Porch Overlooking Marsh- Short Walk to Beach

Edisto Beach

frank r.

$320 nightly

Apr 12 - Apr 13

Total with taxes and fees

New Downtown 2bd w. Modern Southern Charm

Historic District

Adrienne F.

$302 nightly

Apr 14 - Apr 15

Total with taxes and fees

Relaxing resort home, newly renovated

Edisto Beach

Thomas S.

$398 nightly

May 2 - May 3

Total with taxes and fees

Charming Coastal Casa on Beaufort's Battery Creek

Beaufort

Jeremy G.

$203 nightly

Apr 16 - Apr 17

Total with taxes and fees

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Top Ladys Island Hotel Reviews

Island Links Resort by Palmera

8/10 Good

"Full kitchen, clean and spacious rooms. Around a mile away from islanders beach."

Palmera Inn and Suites

2/10 Terrible

"⭐️⭐️ 2/5 – Very Disappointing Experience (Especially for Dog Owners) We chose this hotel because it was labeled as “dog-friendly,” but our experience was far from welcoming. Upon arrival, we walked into the lobby with our dog, Coopie, to check in and were immediately yelled at by multiple staff members. We were told that unless she was a service dog, she was not allowed in the lobby. While she is a service dog, the way this was handled was completely unprofessional and uncomfortable. We’ve traveled to many hotels over the years—both before and after she became a service dog—and have never experienced anything like this. It’s important to note: this hotel being “dog-friendly” only seems to apply to having your dog inside the room—not in shared spaces—so keep that in mind if you’re traveling with a pet. As for the hotel itself, it’s very basic and clearly outdated. The room felt neglected, with visible stains on the bedding, and the floors and bathroom did not appear clean. Overall cleanliness was a major concern. Customer service was also disappointing. The front desk staff came across as rude and unwelcoming. Simple requests—like asking for extra towels or clean sheets—were met with attitude, which is frustrating considering this is standard service you expect from any hotel. On top of everything, the general attitude toward dogs felt very negative, which made the stay even more uncomfortable. Overall: This hotel may work if you just need a place to sleep"

Home2 Suites by Hilton Hilton Head

6/10 Okay

"The building and outside areas are very nice and well kept. While most of the staff were incredibly nice and helpful, I think they were overwhelmed. It was Easter weekend. There was no coffee available on Saturday at 7:30 am (it should be flowing by that point). When I asked about room cleaning Saturday and fresh towels they mentioned that they only clean every other day. Then they called us back to say they would clean anyway—which was very nice. So we once again made sure to get out with the dog and wait an hour, but returning two hours later there was no room cleaning. But the price was good and the hotel was clean, so overall it’s an affordable solution to a very expensive area. "

Omni Hilton Head Oceanfront Resort

6/10 Okay

"The hotel staff is amazing but the pool bar and market seemed understaffed given the hotel capacity. We had a room issue arise in the middle of the night and it was handled well but still disappointing. Overall the property is beautiful and the amenities are wonderful but I think they could use some refresh on standards and an increase in staff."

Find out more about Ladys Island

Everything you need to know about Ladys Island vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Ladys Island vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Ladys Island vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Ladys Island vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Ladys Island. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Ladys Island in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $329 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Ladys Island rentals

At Expedia, we put the best Ladys Island vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Ladys Island rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Ladys Island vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Ladys Island. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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Check prices for these dates

Our top choices for Ladys Island vacation rentals

Sand In My Boots, Minutes to Parris Island & Beaufort and the beach!

Relax under the Shade of a Live Oak! MCRD Paris Island and MCAS 10 Minute Drive

Amazing Airstream, Beaufort, SC-Enjoy the Journey!

501 Sunsuite

Tranquility by the Beach 1st Fl Sleeps 6,King Bed

Ocean Front & pool view. Hunting Island pass included

All Inn on Edisto - Cozy Studio Condo Close to Everything

Cozy Edisto Condo-Close to the Beach!

Gorgeous Waterfront Battery Creek Retreat

The Grey Pearl on Port Royal's Battery Creek

Mariners' Nautical Nest on Port Royal's Battery Creek

'wright by the Beach': Hilton Head Condo w/ Perks

Frippin Fun Vacation - Fripp Island

Coastal Elegance. Poolside. Just steps from the beach! Cards available.

Newly Renovated, Spacious 2bd Apartment w. Parking!

King Suite at The Emerald, Spa Bathroom w. Robes!

Relax on Huge Porch Overlooking Marsh- Short Walk to Beach

New Downtown 2bd w. Modern Southern Charm

Relaxing resort home, newly renovated

Charming Coastal Casa on Beaufort's Battery Creek

Find vacation rentals that suit your style

Top Ladys Island Hotel Reviews

Island Links Resort by Palmera

Find out more about Ladys Island

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