Ladys Island Vacation Rentals

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Our top choices for Ladys Island vacation rentals

Relax under the Shade of a Live Oak! MCRD Paris Island and MCAS 10 Minute Drive

Relax under the Shade of a Live Oak! MCRD Paris Island and MCAS 10 Minute Drive
Beaufort
10.0 out of 10, Exceptional, (7 reviews)
"I had success a wonderful stay !!!"
United States
Jasminee L.
$401 nightly
The price is $441
Mar 30 - Mar 31
Total with taxes and fees
Relax under the Shade of a Live Oak! MCRD Paris Island and MCAS 10 Minute Drive

Sand In My Boots, Minutes to Parris Island & Beaufort and the beach!

Sand In My Boots, Minutes to Parris Island & Beaufort and the beach!
Beaufort
10.0 out of 10, Exceptional, (16 reviews)
"Family visit for HS Graduation - very accommodating hosts were great communicators. All we needed for a beach day too! Thanks Antonio and family!"
United States
Patrick G.
$396 nightly
The price is $436
Apr 18 - Apr 19
Total with taxes and fees
Sand In My Boots, Minutes to Parris Island & Beaufort and the beach!

Marriott's SurfWatch

Marriott's SurfWatch
3.5 star property
Mid Island
9.6 out of 10, Exceptional, (196 reviews)
"Very clean room and resort "
United States
Larisa
$511 nightly
The price is $562
Apr 11 - Apr 12
Total with taxes and fees
Marriott's SurfWatch

Marriott's Harbour Club

Marriott's Harbour Club
3.5 star property
Sea Pines
9.0 out of 10, Wonderful, (63 reviews)
"We are vacation club owner and we extended our stay with Hotels.com Harbor Club is our favorite property on HHI. "
United States
Mark
$279 nightly
The price is $307
Apr 11 - Apr 12
Total with taxes and fees
Marriott's Harbour Club

Disney's Hilton Head Island Resort

Disney's Hilton Head Island Resort
3.5 star property
Mid Island
9.6 out of 10, Exceptional, (128 reviews)
"While the rooms are overdue a refurbishment, this place is a wondeful resort. "
United States
Chad
$347 nightly
The price is $382
Apr 23 - Apr 24
Total with taxes and fees
Disney's Hilton Head Island Resort

Edisto Beach House with Lift

Edisto Beach House with Lift
Edisto Beach
10.0 out of 10, Exceptional, (8 reviews)
"Close to the beach. Plenty of room. Enough parking to accommodate all of us and my son’s golf car trailer. We liked the outdoor shower."
United States
Debbie L.
$966 nightly
The price is $1,044
Mar 30 - Mar 31
Total with taxes and fees
Edisto Beach House with Lift

Ocean Front & pool view. Hunting Island pass included

Ocean Front & pool view. Hunting Island pass included
Beachwalk
9.8 out of 10, Exceptional, (67 reviews)
"great stay at a great location "
United States
Greg B.
$362 nightly
The price is $398
Apr 1 - Apr 2
Total with taxes and fees
Ocean Front & pool view. Hunting Island pass included

Relaxing resort home, newly renovated

Relaxing resort home, newly renovated
Edisto Beach
9.8 out of 10, Exceptional, (177 reviews)
"Very clean, nice location on golf course "
United States
Thomas S.
Relaxing resort home, newly renovated

Seawatch at Island Club

Seawatch at Island Club
3.0 star property
Mid Island
9.2 out of 10, Wonderful, (37 reviews)
"Excellent place with plenty of room, well kept and very clean."
United States
Michelle
Seawatch at Island Club

Free Heated Pool, 3 Blocks to Beach, Elevator, Hot Tub, Kids Room, 3D Theater, EV Charger

Free Heated Pool, 3 Blocks to Beach, Elevator, Hot Tub, Kids Room, 3D Theater, EV Charger
Mid Island
10.0 out of 10, Exceptional, (58 reviews)
"It was the perfect place to hang out and location for our soccer games "
United States
Kevin B.
$2,137 nightly
The price is $2,350
Mar 30 - Mar 31
Total with taxes and fees
Free Heated Pool, 3 Blocks to Beach, Elevator, Hot Tub, Kids Room, 3D Theater, EV Charger

Relax on Huge Porch Overlooking Marsh- Short Walk to Beach

Relax on Huge Porch Overlooking Marsh- Short Walk to Beach
Edisto Beach
9.6 out of 10, Exceptional, (176 reviews)
"Everything we found upon our arrival was as advertised. We really enjoyed the back porch and view of the marsh. "
United States
frank r.
$315 nightly
The price is $353
Apr 10 - Apr 11
Total with taxes and fees
Relax on Huge Porch Overlooking Marsh- Short Walk to Beach

Tranquility by the Beach 1st Fl Sleeps 6,King Bed

Tranquility by the Beach 1st Fl Sleeps 6,King Bed
Mid Island
9.4 out of 10, Exceptional, (55 reviews)
"Relaxing and comfortable stay"
United States
cheryl j.
$253 nightly
The price is $278
Apr 20 - Apr 21
Total with taxes and fees
Tranquility by the Beach 1st Fl Sleeps 6,King Bed

Marriott's Harbour Point and Sunset Pointe at Shelter Cove

Marriott's Harbour Point and Sunset Pointe at Shelter Cove
3.5 star property
Mid Island
9.2 out of 10, Wonderful, (150 reviews)
"Very nice place to stay "
United States
Alejandro
$287 nightly
The price is $316
Apr 11 - Apr 12
Total with taxes and fees
Marriott's Harbour Point and Sunset Pointe at Shelter Cove

Marriott's Heritage Club

Marriott's Heritage Club
3.5 star property
Sea Pines
9.4 out of 10, Exceptional, (67 reviews)
"Another great Marriott, super clean and spacious with the comforts we needed to finish out a long trip (e.g. hot tub, laundry, kitchen). Friendly staff and convenient to the forest reserve."
United States
Landry
$387 nightly
The price is $426
Apr 11 - Apr 12
Total with taxes and fees
Marriott's Heritage Club

Newly Renovated, Spacious 2bd Apartment w. Parking!

Newly Renovated, Spacious 2bd Apartment w. Parking!
Historic District
9.8 out of 10, Exceptional, (16 reviews)
"Love the condo. Perfect location. Excellent communication. 5 stars "
United States
Debby
$367 nightly
The price is $415
Mar 30 - Mar 31
Total with taxes and fees
Newly Renovated, Spacious 2bd Apartment w. Parking!

13SC Beach, Private Pool, 10 foot movie theater screen

13SC Beach, Private Pool, 10 foot movie theater screen
Mid Island
10.0 out of 10, Exceptional, (24 reviews)
"It was amazing! We were thoroughly impressed with the property, the heated pool, the amenities, the cleanliness and the overall ease with which we checked in and out. "
United States
Kristen D.
$1,555 nightly
The price is $1,710
Apr 1 - Apr 2
Total with taxes and fees
13SC Beach, Private Pool, 10 foot movie theater screen

Gated Community, Close to beach, heated pool, golf cart available

Gated Community, Close to beach, heated pool, golf cart available
Mid Island
9.8 out of 10, Exceptional, (87 reviews)
"We loved staying here, the beach is close, the pool was heated and great for a kid."
United States
Geoffrey Y.
$1,241 nightly
The price is $1,365
Mar 30 - Mar 31
Total with taxes and fees
Gated Community, Close to beach, heated pool, golf cart available

Cozy Edisto Condo-Close to the Beach!

Cozy Edisto Condo-Close to the Beach!
Edisto Beach
9.0 out of 10, Wonderful, (92 reviews)
"Great place for our quick weekend get away! "
United States
Ronda J.
$165 nightly
The price is $185
Apr 11 - Apr 12
Total with taxes and fees
Cozy Edisto Condo-Close to the Beach!

2031 Deer Island Treehouse Walkable to Harbour Town

2031 Deer Island Treehouse Walkable to Harbour Town
Sea Pines
9.6 out of 10, Exceptional, (67 reviews)
"Loved staying there. Place was perfect for us."
United States
Debra M.
$452 nightly
The price is $497
Apr 12 - Apr 13
Total with taxes and fees
2031 Deer Island Treehouse Walkable to Harbour Town

Old Town + Modern 4 BR + Fire Pit + EV Charger

Old Town + Modern 4 BR + Fire Pit + EV Charger
Old Town Bluffton
9.4 out of 10, Exceptional, (28 reviews)
"The home and the amenities were perfect for our needs. Would highly recommend."
United States
Sean F.
$847 nightly
The price is $895
Apr 5 - Apr 6
Total with taxes and fees
Old Town + Modern 4 BR + Fire Pit + EV Charger
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Ladys Island Hotel Reviews

Find out more about Ladys Island

Everything you need to know about Ladys Island vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Ladys Island vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Ladys Island vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Ladys Island vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Ladys Island. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Ladys Island in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $317 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Ladys Island rentals

At Expedia, we put the best Ladys Island vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Ladys Island rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Ladys Island vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Ladys Island. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.