A marshy landscape with water, trees, and a distant city skyline.

Ladys Island Vacation Rentals

  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals

  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings

  • Upfront pricing

    We are not like the others - we include taxes and fees

Check prices for these dates

In two weeks
Nov 27 - Nov 29
In two months
Jan 8 - Jan 10
In three months
Feb 5 - Feb 7
In four months
Mar 5 - Mar 7

Our top choices for Ladys Island vacation rentals

A modern kitchen with a large island, stainless steel appliances, and pendant lighting.

1. Relax under the Shade of a Live Oak! MCRD Paris Island and MCAS 10 Minute Drive

Relax under the Shade of a Live Oak! MCRD Paris Island and MCAS 10 Minute Drive
Beaufort
10.0 out of 10, Exceptional, (17 reviews)
"Great location close to downtown newly renovated home with everything we could ask for. Would definitely book again on our next trip"
United States
adam s.
$424 nightly
The price is $466
Nov 10 - Nov 11
Total with taxes and fees
Relax under the Shade of a Live Oak! MCRD Paris Island and MCAS 10 Minute Drive
A hotel room with a bed, two bedside tables with lamps, a ceiling fan, and a door.

2. New Downtown 2bd w. Modern Southern Charm

New Downtown 2bd w. Modern Southern Charm
Historic District
9.8 out of 10, Exceptional, (30 reviews)
"Great location, very comfortable, easy parking, and easy walk to Bay St. shops and restaurants."
United States
Tim
$293 nightly
The price is $333
Dec 6 - Dec 7
Total with taxes and fees
New Downtown 2bd w. Modern Southern Charm
A wooden deck with a glass table and chairs, overlooking a lake with trees and a distant building.

3. The Drift at Port Royal on Battery Creek

The Drift at Port Royal on Battery Creek
Beaufort
10.0 out of 10, Exceptional, (14 reviews)
"We loved our stay and plan to rent from you again."
United States
Anita M.
$175 nightly
The price is $193
Nov 14 - Nov 15
Total with taxes and fees
The Drift at Port Royal on Battery Creek
A covered outdoor seating area with wicker furniture and a glass table, overlooking a body of water.

4. Modern Coastal Escape on Beaufort's Battery Creek

Modern Coastal Escape on Beaufort's Battery Creek
Beaufort
9.6 out of 10, Exceptional, (42 reviews)
"It is a great location to stay to visit Parris Island and the area is beautiful"
United States
Paula B.
$220 nightly
The price is $242
Nov 10 - Nov 11
Total with taxes and fees
Modern Coastal Escape on Beaufort's Battery Creek
A dining area with a wooden table, white chairs, a bench, a chandelier, and a patterned rug.

5. 3 BR/2 Bath Historic District~ 7 Bl to Downtown~20 mins to BEACH/Pass INCL

3 BR/2 Bath Historic District~ 7 Bl to Downtown~20 mins to BEACH/Pass INCL
Historic District
9.8 out of 10, Exceptional, (106 reviews)
"Great location!"
United States
Maria F.
$312 nightly
The price is $343
Nov 30 - Dec 1
Total with taxes and fees
3 BR/2 Bath Historic District~ 7 Bl to Downtown~20 mins to BEACH/Pass INCL
A modern kitchen with white cabinetry, a wooden island with stools, a stone fireplace, and a view of the ocean through large windows.

6. Gorgeous Waterfront Battery Creek Retreat

Gorgeous Waterfront Battery Creek Retreat
Beaufort
9.8 out of 10, Exceptional, (129 reviews)
"Loved the views. Would definitely rent again."
United States
Thomas F.
$175 nightly
The price is $193
Nov 10 - Nov 11
Total with taxes and fees
Gorgeous Waterfront Battery Creek Retreat
A modern living space with a kitchen, dining area, and a seating area with a view.

7. The Grey Pearl on Port Royal's Battery Creek

The Grey Pearl on Port Royal's Battery Creek
Beaufort
9.8 out of 10, Exceptional, (45 reviews)
"Great and clean place to stay if you are wanting something close by to Parris Island for those who have loved ones graduating from basic training for the Marines. There aren’t any amenities but the Hunting Beach State Park is really nice and only about 30 minutes away."
United States
Sherry H.
$170 nightly
The price is $187
Nov 10 - Nov 11
Total with taxes and fees
The Grey Pearl on Port Royal's Battery Creek
A covered patio with two chairs and a table, overlooking a lake with a fence in the background.

8. Charming Coastal Casa on Beaufort's Battery Creek

Charming Coastal Casa on Beaufort's Battery Creek
Beaufort
9.8 out of 10, Exceptional, (54 reviews)
"The view was worth it, peaceful"
United States
Amanda
$175 nightly
The price is $193
Nov 10 - Nov 11
Total with taxes and fees
Charming Coastal Casa on Beaufort's Battery Creek
A spacious living area with a brown leather couch, a white sofa, a dining table with chairs, a kitchen with white cabinets, a ceiling fan, and a large sliding glass door leading to an outdoor patio.

9. Mariners' Nautical Nest on Port Royal's Battery Creek

Mariners' Nautical Nest on Port Royal's Battery Creek
Beaufort
9.8 out of 10, Exceptional, (50 reviews)
"Great place, very informative host!!"
United States
John M.
$187 nightly
The price is $206
Dec 1 - Dec 2
Total with taxes and fees
Mariners' Nautical Nest on Port Royal's Battery Creek
An outdoor seating area with wicker furniture and a glass table, overlooking a body of water and a grassy area.

10. Beaufort's Blue Heron Hideaway on Battery Creek

Beaufort's Blue Heron Hideaway on Battery Creek
Beaufort
9.4 out of 10, Exceptional, (43 reviews)
"Liked it all cozy clean great view simple easy to find great stay thanks alex"
United States
alex
$188 nightly
The price is $207
Nov 16 - Nov 17
Total with taxes and fees
Beaufort's Blue Heron Hideaway on Battery Creek
A room with a bed, a hanging chair, a chair, and a window.

11. The Offbeat Oasis by the Marsh- State Park Pass Included🏖

The Offbeat Oasis by the Marsh- State Park Pass Included🏖
Saint Helena Island
9.8 out of 10, Exceptional, (20 reviews)
"Beautiful setting, everything you need inside, not a private location, another small "cabin" behind it sharing the yard area and very close. A second cabin within sight of this one, all three using the same driveway. "
United States
Ann N.
$284 nightly
The price is $312
Nov 10 - Nov 11
Total with taxes and fees
The Offbeat Oasis by the Marsh- State Park Pass Included🏖
A view from a room with a large window overlooking a lake, surrounded by trees and a patio area with chairs and a table.

12. Waterfront – 3 Min to Parris Island Sleeps 4 - Stunning Views

Waterfront – 3 Min to Parris Island Sleeps 4 - Stunning Views
Beaufort
10.0 out of 10, Exceptional, (46 reviews)
"Everything is description was spot on! The waterfront view was amazing! We loved the baby crabs that would even come right up to patio!! We would absolutely stay again!"
United States
Lindsay W.
$365 nightly
The price is $402
Nov 14 - Nov 15
Total with taxes and fees
Waterfront – 3 Min to Parris Island Sleeps 4 - Stunning Views
A compact room with bunk beds, a kitchenette, and a balcony with a view of buildings.

13. Oceanside, steps to the Beach, pets considered, cards avail, Beach Club Complex

Oceanside, steps to the Beach, pets considered, cards avail, Beach Club Complex
Saint Helena Island
8.4 out of 10, Very good, (40 reviews)
"Greta location, right by the beach."
United States
javier m.
$267 nightly
The price is $294
Nov 10 - Nov 11
Total with taxes and fees
Oceanside, steps to the Beach, pets considered, cards avail, Beach Club Complex
A modern living room with a blue sofa, white armchair, and a coffee table. A TV is mounted on the wall, and there is a sliding glass door leading to a balcony.

14. Frippin Fun Vacation - Fripp Island

Frippin Fun Vacation - Fripp Island
Saint Helena Island
8.8 out of 10, Excellent, (50 reviews)
"Perfect one bedroom condo and in a great location.."
United States
Wendie C.
$238 nightly
The price is $262
Nov 16 - Nov 17
Total with taxes and fees
Frippin Fun Vacation - Fripp Island
A covered outdoor seating area with a view of the sunset over a body of water.

15. Marriott's Harbour Point and Sunset Pointe at Shelter Cove

Marriott's Harbour Point and Sunset Pointe at Shelter Cove
3.5 star property
Mid Island
9.2 out of 10, Wonderful, (159 reviews)
"It was a very nice vacation club. They had activities planned throughout the day that you could attend if you’d like. My kids really enjoyed themselves."
United States
Gary T
$87 nightly
The price is $96
Nov 30 - Dec 1
Total with taxes and fees
Marriott's Harbour Point and Sunset Pointe at Shelter Cove
A compact kitchen with a dining area, a television, and a chandelier.

16. Relax & Regroup at the Beach- HUGE Fall discounts! Check us out!

Relax & Regroup at the Beach- HUGE Fall discounts! Check us out!
Fripp Island
9.8 out of 10, Exceptional, (118 reviews)
"Perfect spot for a quiet getaway. We loved our stay!"
United States
Jennifer M.
$377 nightly
The price is $414
Nov 10 - Nov 11
Total with taxes and fees
Relax & Regroup at the Beach- HUGE Fall discounts! Check us out!
A balcony with a table and two chairs, overlooking a swimming pool and beachfront houses.

17. St Helena Island Condo - 1/2 Mi to Beach

St Helena Island Condo - 1/2 Mi to Beach
Beachwalk
10.0 out of 10, Exceptional, (93 reviews)
"2nd time staying and really enjoyed the clean condo and convenient access to beach and pool."
United States
Ashleigh M.
$352 nightly
The price is $387
Nov 23 - Nov 24
Total with taxes and fees
St Helena Island Condo - 1/2 Mi to Beach
A pool area with a covered pavilion, a building under construction, and a view of the surrounding trees.

18. Coastal Elegance. Poolside. Just steps from the beach! Cards available.

Coastal Elegance. Poolside. Just steps from the beach! Cards available.
Fripp Island
9.2 out of 10, Wonderful, (123 reviews)
"Great place"
United States
John C.
$340 nightly
The price is $374
Nov 11 - Nov 12
Total with taxes and fees
Coastal Elegance. Poolside. Just steps from the beach! Cards available.
A poolside view with a sunset over the ocean, a palm tree, and a deck with chairs.

19. Coastline Cottage with Breathtaking Ocean Views On Fripp Island Wi-Fi, Golf Cart

Coastline Cottage with Breathtaking Ocean Views On Fripp Island Wi-Fi, Golf Cart
Saint Helena Island
10.0 out of 10, Exceptional, (41 reviews)
"Such a great place for a get away! Communication with the host was easy and we plan to stay again! "
United States
Samantha E.
$379 nightly
The price is $417
Dec 1 - Dec 2
Total with taxes and fees
Coastline Cottage with Breathtaking Ocean Views On Fripp Island Wi-Fi, Golf Cart
A beachside resort with a swimming pool, lounge chairs, and a small building, likely a lifeguard station.

20. Steps to the beach! Newly Remodeled! New furniture STR Permit #: 072116

Steps to the beach! Newly Remodeled! New furniture STR Permit #: 072116
Mid Island
9.6 out of 10, Exceptional, (120 reviews)
"Short, but enjoyable stay. Would stay again!"
United States
Dora D.
$280 nightly
The price is $308
Nov 18 - Nov 19
Total with taxes and fees
Steps to the beach! Newly Remodeled! New furniture STR Permit #: 072116
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Ladys Island Hotel Reviews

Palmera Inn and Suites

Palmera Inn and Suites

10/10 Excellent
"Great place! Front desk staff was friendly. Bar service was great. Loved the location. I would definitely stay again."
Laura 1-night trip
Posted 8 hours ago
Palmera Inn and Suites

Find out more about Ladys Island

Everything you need to know about Ladys Island vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Ladys Island vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Ladys Island vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Ladys Island vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Ladys Island. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Ladys Island in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $96 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Ladys Island rentals

At Expedia, we put the best Ladys Island vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Ladys Island rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Ladys Island vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Ladys Island. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia