Ladys Island Vacation Rentals

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Our top choices for Ladys Island vacation rentals

Sand In My Boots, Minutes to Parris Island & Beaufort and the beach!

Sand In My Boots, Minutes to Parris Island & Beaufort and the beach!
Beaufort
10.0 out of 10, Exceptional, (17 reviews)
"We really enjoyed staying at your place, while attending our sons graduation from Parris Island."
United States
Traci B.
$397 nightly
The price is $437
Apr 18 - Apr 19
Total with taxes and fees
Sand In My Boots, Minutes to Parris Island & Beaufort and the beach!

Relax under the Shade of a Live Oak! MCRD Paris Island and MCAS 10 Minute Drive

Relax under the Shade of a Live Oak! MCRD Paris Island and MCAS 10 Minute Drive
Beaufort
10.0 out of 10, Exceptional, (8 reviews)
"I had success a wonderful stay !!!"
United States
Jasminee L.
$404 nightly
The price is $444
Apr 13 - Apr 14
Total with taxes and fees
Relax under the Shade of a Live Oak! MCRD Paris Island and MCAS 10 Minute Drive

Gentleman Pirate (Ocean Views!)

Gentleman Pirate (Ocean Views!)
Edisto Beach
10.0 out of 10, Exceptional, (19 reviews)
"Great vacation home!"
United States
Samuel J.
$404 nightly
The price is $452
Apr 15 - Apr 16
Total with taxes and fees
Gentleman Pirate (Ocean Views!)

A Room With a View-1 BR Efficiency Condo Close to Everything.

A Room With a View-1 BR Efficiency Condo Close to Everything.
Edisto Beach
9.8 out of 10, Exceptional, (135 reviews)
"Perfect spot "
United States
Jennifer S.
$179 nightly
The price is $200
Apr 14 - Apr 15
Total with taxes and fees
A Room With a View-1 BR Efficiency Condo Close to Everything.

501 Sunsuite

501 Sunsuite
Fripp Island
9.8 out of 10, Exceptional, (11 reviews)
"This was a super getaway. From the friendly gate greeting, the comfortable, attractive room, the quick walk to the beach and everything for a wonderful 2 night stay! We hope to visit again!"
United States
Robbie
$368 nightly
The price is $415
Apr 13 - Apr 14
Total with taxes and fees
501 Sunsuite

Gorgeous Waterfront Battery Creek Retreat

Gorgeous Waterfront Battery Creek Retreat
Beaufort
9.8 out of 10, Exceptional, (100 reviews)
"Great stay! Private, cozy, and quiet with a great view of the water and marsh."
United States
Jad
$188 nightly
The price is $207
Apr 16 - Apr 17
Total with taxes and fees
Gorgeous Waterfront Battery Creek Retreat

Mariners' Nautical Nest on Port Royal's Battery Creek

Mariners' Nautical Nest on Port Royal's Battery Creek
Beaufort
10.0 out of 10, Exceptional, (31 reviews)
"We so loved our stay! Our stay was AMAZING! Great location, great views, and the downtown area is very close and easy to get to. Cannot wait to rebook your place!! "
United States
Glenn G.
$198 nightly
The price is $218
Apr 20 - Apr 21
Total with taxes and fees
Mariners' Nautical Nest on Port Royal's Battery Creek

Ocean Front & pool view. Hunting Island pass included

Ocean Front & pool view. Hunting Island pass included
Beachwalk
9.8 out of 10, Exceptional, (67 reviews)
"great stay at a great location "
United States
Greg B.
$364 nightly
The price is $400
Apr 13 - Apr 14
Total with taxes and fees
Ocean Front & pool view. Hunting Island pass included

Tranquility by the Beach 1st Fl Sleeps 6,King Bed

Tranquility by the Beach 1st Fl Sleeps 6,King Bed
Mid Island
9.4 out of 10, Exceptional, (56 reviews)
"Nice condo. Easy walk to beach."
United States
A. D.
$257 nightly
The price is $283
Apr 20 - Apr 21
Total with taxes and fees
Tranquility by the Beach 1st Fl Sleeps 6,King Bed

Cozy Edisto Condo-Close to the Beach!

Cozy Edisto Condo-Close to the Beach!
Edisto Beach
9.0 out of 10, Wonderful, (94 reviews)
"Great place for our quick weekend get away! "
United States
Ronda J.
$165 nightly
The price is $185
Apr 14 - Apr 15
Total with taxes and fees
Cozy Edisto Condo-Close to the Beach!

All Inn on Edisto - Cozy Studio Condo Close to Everything

All Inn on Edisto - Cozy Studio Condo Close to Everything
Edisto Beach
9.8 out of 10, Exceptional, (160 reviews)
"Excellent cute little studio apartment. Thoroughly enjoyed coming back and resting after a long day of work."
United States
Cabell G.
$179 nightly
The price is $200
Apr 26 - Apr 27
Total with taxes and fees
All Inn on Edisto - Cozy Studio Condo Close to Everything

'wright by the Beach': Hilton Head Condo w/ Perks

'wright by the Beach': Hilton Head Condo w/ Perks
3.0 star property
Mid Island
10.0 out of 10, Exceptional, (1 review)
"We enjoyed our stay. We loved the ocean theme at the apartment. Very clean rooms. Kids enjoyed swimming in the indoor pool, parents enjoyed hot tub and sauna especially on rainy days. They have indoor and outdoor pools. We liked walking on the boardwalk to the beach. We highly recommend this place and would love to return there again. "
United States
Victor
$249 nightly
The price is $274
Apr 13 - Apr 14
Total with taxes and fees
'wright by the Beach': Hilton Head Condo w/ Perks

The Grey Pearl on Port Royal's Battery Creek

The Grey Pearl on Port Royal's Battery Creek
Beaufort
10.0 out of 10, Exceptional, (24 reviews)
"Great property "
United States
Caleb C.
$183 nightly
The price is $201
Apr 16 - Apr 17
Total with taxes and fees
The Grey Pearl on Port Royal's Battery Creek

New Downtown 2bd w. Modern Southern Charm

New Downtown 2bd w. Modern Southern Charm
Historic District
9.8 out of 10, Exceptional, (20 reviews)
"Great location, excellent communication with host, unit was well appointed. Definitely recommend. "
United States
Adrienne F.
$306 nightly
The price is $346
Apr 13 - Apr 14
Total with taxes and fees
New Downtown 2bd w. Modern Southern Charm

🌴Book Now For Summer 🌴10% Off A Week Stay🌞Beach is approx 1 mile🌴 sleeps 2-4

🌴Book Now For Summer 🌴10% Off A Week Stay🌞Beach is approx 1 mile🌴 sleeps 2-4
Edisto Beach
9.6 out of 10, Exceptional, (38 reviews)
"Very nice property, convenient to the beach and restaurants "
United States
Shaun H.
$269 nightly
The price is $301
Apr 20 - Apr 21
Total with taxes and fees
🌴Book Now For Summer 🌴10% Off A Week Stay🌞Beach is approx 1 mile🌴 sleeps 2-4

Relax on Huge Porch Overlooking Marsh- Short Walk to Beach

Relax on Huge Porch Overlooking Marsh- Short Walk to Beach
Edisto Beach
9.6 out of 10, Exceptional, (178 reviews)
"Everything we found upon our arrival was as advertised. We really enjoyed the back porch and view of the marsh. "
United States
frank r.
$318 nightly
The price is $356
Apr 13 - Apr 14
Total with taxes and fees
Relax on Huge Porch Overlooking Marsh- Short Walk to Beach

Coastal Elegance. Poolside. Just steps from the beach! Cards available.

Coastal Elegance. Poolside. Just steps from the beach! Cards available.
Fripp Island
9.4 out of 10, Exceptional, (114 reviews)
"Great spot, close to the beach. "
United States
Eric D.
$323 nightly
The price is $355
Apr 13 - Apr 14
Total with taxes and fees
Coastal Elegance. Poolside. Just steps from the beach! Cards available.

Newly Renovated, Spacious 2bd Apartment w. Parking!

Newly Renovated, Spacious 2bd Apartment w. Parking!
Historic District
9.8 out of 10, Exceptional, (16 reviews)
"Love the condo. Perfect location. Excellent communication. 5 stars "
United States
Debby
$306 nightly
The price is $346
Apr 13 - Apr 14
Total with taxes and fees
Newly Renovated, Spacious 2bd Apartment w. Parking!

Frippin Fun Vacation - Fripp Island

Frippin Fun Vacation - Fripp Island
Saint Helena Island
9.4 out of 10, Exceptional, (37 reviews)
"My husband and I had a great vacation! The view was wonderful and we saw an abundance of wildlife. Very relaxing!"
United States
Amy C.
$319 nightly
The price is $351
May 1 - May 2
Total with taxes and fees
Frippin Fun Vacation - Fripp Island

King Suite at The Emerald, Spa Bathroom w. Robes!

King Suite at The Emerald, Spa Bathroom w. Robes!
Historic District
9.6 out of 10, Exceptional, (33 reviews)
"Wonderful stay, had everything we needed and loves the location. We will be staying here again!"
United States
Leah R.
$181 nightly
The price is $205
Apr 13 - Apr 14
Total with taxes and fees
King Suite at The Emerald, Spa Bathroom w. Robes!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Ladys Island Hotel Reviews

Find out more about Ladys Island

Everything you need to know about Ladys Island vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Ladys Island vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Ladys Island vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Ladys Island vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Ladys Island. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Ladys Island in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $301 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Ladys Island rentals

At Expedia, we put the best Ladys Island vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Ladys Island rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Ladys Island vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Ladys Island. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.