A marshy landscape with water, trees, and a distant city skyline.

Ladys Island Vacation Rentals

  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals

  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings

  • Upfront pricing

    We are not like the others - we include taxes and fees

Check prices for these dates

In two weeks
Oct 16 - Oct 18
In two months
Nov 27 - Nov 29
In three months
Dec 25 - Dec 27
In four months
Jan 22 - Jan 24

Our top choices for Ladys Island vacation rentals

A modern kitchen with a large island, stainless steel appliances, and pendant lighting.

1. Relax under the Shade of a Live Oak! MCRD Paris Island and MCAS 10 Minute Drive

Relax under the Shade of a Live Oak! MCRD Paris Island and MCAS 10 Minute Drive
Beaufort
10.0 out of 10, Exceptional, (16 reviews)
"Great location close to downtown newly renovated home with everything we could ask for. Would definitely book again on our next trip"
United States
adam s.
$457 nightly
The price is $503
Oct 10 - Oct 11
Total with taxes and fees
Relax under the Shade of a Live Oak! MCRD Paris Island and MCAS 10 Minute Drive
A hotel room with a large bed, a bench, a ceiling fan, an air conditioning unit, a window with curtains, and a view of buildings outside.

2. Superior King Suite w Rain Shower, Bikes, Coffee!

Superior King Suite w Rain Shower, Bikes, Coffee!
Historic District
9.6 out of 10, Exceptional, (13 reviews)
"The location was excellent, within walking distance of shops and restaurants. The rooms were clean, though not spotless. Overall, everything else was very good, and I would definitely stay here again."
United States
Tatiana
$191 nightly
The price is $216
Oct 12 - Oct 13
Total with taxes and fees
Superior King Suite w Rain Shower, Bikes, Coffee!
A hallway with a wooden floor, a white door with a window, and a small table with a welcome sign.

3. New Downtown 2bd w. Modern Southern Charm

New Downtown 2bd w. Modern Southern Charm
Historic District
10.0 out of 10, Exceptional, (27 reviews)
"Great location, very comfortable, easy parking, and easy walk to Bay St. shops and restaurants."
United States
Tim
$337 nightly
The price is $382
Oct 11 - Oct 12
Total with taxes and fees
New Downtown 2bd w. Modern Southern Charm
A wooden pier extending into calm waters with several fishing boats docked at the end.

4. 3 BR/2 Bath Historic District~ 7 Bl to Downtown~20 mins to BEACH/Pass INCL

3 BR/2 Bath Historic District~ 7 Bl to Downtown~20 mins to BEACH/Pass INCL
Historic District
9.8 out of 10, Exceptional, (104 reviews)
"Enjoyed our stay. Cute and comfortable. Wish we were able to take better advantage of the big back yard. A pleasant walk to the downtown area."
United States
Richard S.
$344 nightly
The price is $377
Oct 9 - Oct 10
Total with taxes and fees
3 BR/2 Bath Historic District~ 7 Bl to Downtown~20 mins to BEACH/Pass INCL
A modern kitchen with white cabinetry, a wooden island with stools, a stone fireplace, and a view of the ocean through large windows.

5. Gorgeous Waterfront Battery Creek Retreat

Gorgeous Waterfront Battery Creek Retreat
Beaufort
10.0 out of 10, Exceptional, (122 reviews)
"The location was lovely and made for the perfect getaway. "
United States
Jim S.
$186 nightly
The price is $205
Oct 4 - Oct 5
Total with taxes and fees
Gorgeous Waterfront Battery Creek Retreat
A wooden deck with a glass table and chairs, overlooking a lake with trees and a distant building.

6. The Drift at Port Royal on Battery Creek

The Drift at Port Royal on Battery Creek
Beaufort
10.0 out of 10, Exceptional, (10 reviews)
"Great property and clean. Easy move in and out. We would recommend this rental for others staying in the area."
United States
Robert F.
$217 nightly
The price is $239
Oct 10 - Oct 11
Total with taxes and fees
The Drift at Port Royal on Battery Creek
A compact RV interior with a kitchenette, a seating area with a sofa and cushions, and a small dining table.

7. Amazing Airstream, Beaufort, SC-Enjoy the Journey!

Amazing Airstream, Beaufort, SC-Enjoy the Journey!
Beaufort
9.4 out of 10, Exceptional, (29 reviews)
"Such a quaint, eclectic Airstream! Loved the decor. It was such a neat place to stay. We were visiting Paris Island because my son will be in basic soon. We hope to stay here again soon! Corner was such a great host. All of his recommendations for food and attractions were on point. Perfect visit."
United States
hunter j.
$159 nightly
The price is $175
Oct 5 - Oct 6
Total with taxes and fees
Amazing Airstream, Beaufort, SC-Enjoy the Journey!
A modern living space with a kitchen, dining area, and a seating area with a view.

8. The Grey Pearl on Port Royal's Battery Creek

The Grey Pearl on Port Royal's Battery Creek
Beaufort
10.0 out of 10, Exceptional, (39 reviews)
"Great property "
United States
Caleb C.
$182 nightly
The price is $200
Oct 4 - Oct 5
Total with taxes and fees
The Grey Pearl on Port Royal's Battery Creek
A covered patio with two chairs and a table, overlooking a lake with a fence in the background.

9. Charming Coastal Casa on Beaufort's Battery Creek

Charming Coastal Casa on Beaufort's Battery Creek
Beaufort
9.8 out of 10, Exceptional, (53 reviews)
"The view was worth it, peaceful"
United States
Amanda
$186 nightly
The price is $205
Oct 5 - Oct 6
Total with taxes and fees
Charming Coastal Casa on Beaufort's Battery Creek
A spacious living area with a brown leather couch, a white sofa, a dining table with chairs, a kitchen with white cabinets, a ceiling fan, and a large sliding glass door leading to an outdoor patio.

10. Mariners' Nautical Nest on Port Royal's Battery Creek

Mariners' Nautical Nest on Port Royal's Battery Creek
Beaufort
9.8 out of 10, Exceptional, (46 reviews)
"Perfect location "
United States
Jayda M.
$186 nightly
The price is $205
Oct 5 - Oct 6
Total with taxes and fees
Mariners' Nautical Nest on Port Royal's Battery Creek
A room with a bed, a hanging chair, a chair, and a window.

11. The Offbeat Oasis by the Marsh- State Park Pass Included🏖

The Offbeat Oasis by the Marsh- State Park Pass Included🏖
Saint Helena Island
9.8 out of 10, Exceptional, (20 reviews)
"Beautiful setting, everything you need inside, not a private location, another small "cabin" behind it sharing the yard area and very close. A second cabin within sight of this one, all three using the same driveway. "
United States
Ann N.
$316 nightly
The price is $348
Oct 4 - Oct 5
Total with taxes and fees
The Offbeat Oasis by the Marsh- State Park Pass Included🏖
A view from a room with a large window overlooking a lake, surrounded by trees and a patio area with chairs and a table.

12. Waterfront – 3 Min to Parris Island Sleeps 4 - Stunning Views

Waterfront – 3 Min to Parris Island Sleeps 4 - Stunning Views
Beaufort
10.0 out of 10, Exceptional, (41 reviews)
"Our stay here was absolutely perfect! Location to Parris Island, Bayside Beaufort, local shops, Beach, restaurants was so convenient. Our hostess was so helpful and attentive; the home had everything we needed or could have hoped for and we loved sitting out back with the picturesque water view."
United States
Kristie T.
$369 nightly
The price is $406
Oct 25 - Oct 26
Total with taxes and fees
Waterfront – 3 Min to Parris Island Sleeps 4 - Stunning Views
A wooden deck with outdoor furniture, a railing, and a view of the beach.

13. Oceanfront St Helena Island Condo w/ Beach Access!

Oceanfront St Helena Island Condo w/ Beach Access!
Saint Helena Island
9.8 out of 10, Exceptional, (83 reviews)
"We have been now to the island a few years now- and every year just gets better! The condo was wonderful- the new upgrades were wonderful and perfect for our family of 4. The big deck and proximity to the beach and pool were great!"
United States
Meaghan W.
$403 nightly
The price is $443
Oct 4 - Oct 5
Total with taxes and fees
Oceanfront St Helena Island Condo w/ Beach Access!
A beach with clear skies and waves.

14. Frippin Fun Vacation - Fripp Island

Frippin Fun Vacation - Fripp Island
Saint Helena Island
9.0 out of 10, Wonderful, (47 reviews)
"Perfect one bedroom condo and in a great location.."
United States
Wendie C.
$295 nightly
The price is $325
Nov 1 - Nov 2
Total with taxes and fees
Frippin Fun Vacation - Fripp Island
A coastal view with palm trees and a beach in the background.

15. Oceanside, steps to the Beach, pets considered, cards avail, Beach Club Complex

Oceanside, steps to the Beach, pets considered, cards avail, Beach Club Complex
Saint Helena Island
8.4 out of 10, Very good, (39 reviews)
"Greta location, right by the beach."
United States
javier m.
$302 nightly
The price is $332
Oct 5 - Oct 6
Total with taxes and fees
Oceanside, steps to the Beach, pets considered, cards avail, Beach Club Complex
A living room with a fireplace, a television, and a dining area with a table and chairs.

16. Ranch, 6 bedrooms and 5 baths home near Parris Island and Beaufort is beautiful.

Ranch, 6 bedrooms and 5 baths home near Parris Island and Beaufort is beautiful.
St Helena Island
9.2 out of 10, Wonderful, (73 reviews)
"My family of 16 and I was here for a wedding. The accommodation was great. The communication with the host was great. "
United States
Lakisha S.
$659 nightly
The price is $725
Oct 2 - Oct 3
Total with taxes and fees
Ranch, 6 bedrooms and 5 baths home near Parris Island and Beaufort is beautiful.
A wide sandy beach with gentle waves and a clear blue sky.

17. Relax & Regroup at the Beach- Let's think about Fall. Check us out!

Relax & Regroup at the Beach- Let's think about Fall. Check us out!
Fripp Island
9.8 out of 10, Exceptional, (115 reviews)
"Perfect spot for a quiet getaway. We loved our stay!"
United States
Jennifer M.
$449 nightly
The price is $494
Oct 4 - Oct 5
Total with taxes and fees
Relax & Regroup at the Beach- Let's think about Fall. Check us out!
A sunset over a beach with a pier extending into the water.

18. Coastal Elegance. Poolside. Just steps from the beach! Cards available.

Coastal Elegance. Poolside. Just steps from the beach! Cards available.
Fripp Island
9.2 out of 10, Wonderful, (122 reviews)
"Great place"
United States
John C.
$350 nightly
The price is $385
Oct 11 - Oct 12
Total with taxes and fees
Coastal Elegance. Poolside. Just steps from the beach! Cards available.
A poolside view with a sunset over the ocean, a palm tree, and a deck with chairs.

19. Coastline Cottage with Breathtaking Ocean Views On Fripp Island Wi-Fi, Golf Cart

Coastline Cottage with Breathtaking Ocean Views On Fripp Island Wi-Fi, Golf Cart
Saint Helena Island
10.0 out of 10, Exceptional, (39 reviews)
"Wonderful ocean views. Beautiful beaches. The best of the barrier islands. Right next to a state park with a lighthouse and great hiking. Would definitely recommend!!"
United States
Christopher B.
$389 nightly
The price is $428
Oct 11 - Oct 12
Total with taxes and fees
Coastline Cottage with Breathtaking Ocean Views On Fripp Island Wi-Fi, Golf Cart
A spacious living area with a large sliding glass door leading to a balcony, a central island with a sink, and a ceiling fan.

20. A Room With a View-1 BR Efficiency Condo Close to Everything.

A Room With a View-1 BR Efficiency Condo Close to Everything.
Edisto Beach
9.6 out of 10, Exceptional, (156 reviews)
"As advertised Cute little room with a view. Close to beaches and local restaurants. Super secluded and safe!!"
United States
Blake
$180 nightly
The price is $201
Oct 4 - Oct 5
Total with taxes and fees
A Room With a View-1 BR Efficiency Condo Close to Everything.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Ladys Island Hotel Reviews

Tru by Hilton Beaufort, SC

Tru by Hilton Beaufort, SC

10/10 Excellent
"Clean room. Friendly staff."
Jessica 1-night trip
Posted 5 hours ago
Tru by Hilton Beaufort, SC

Find out more about Ladys Island

Everything you need to know about Ladys Island vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Ladys Island vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Ladys Island vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Ladys Island vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Ladys Island. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Ladys Island in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $237 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Ladys Island rentals

At Expedia, we put the best Ladys Island vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Ladys Island rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Ladys Island vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Ladys Island. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia