Title: Visit Northeast Missouri: Best of Northeast Missouri Tourism | Expedia Travel Guide - Expedia.com [Hotels in Northeast Missouri](https://expedia.com/Northeast-Missouri-Hotels.d6058818.Travel-Guide-Hotels)[Vacation Rentals in Northeast Missouri](https://expedia.com/Northeast-Missouri-Vacation-Rentals.d6058818.Travel-Guide-VacationRentals)[Flights to Northeast Missouri](https://expedia.com/Cheap-Flights-To-Northeast-Missouri.d6058818.Travel-Guide-Flights)[Things to do in Northeast Missouri](https://expedia.com/Things-To-Do-In-Northeast-Missouri.d6058818.Travel-Guide-Activities)[Car Rentals in Northeast Missouri](https://expedia.com/Car-Rentals-In-Northeast-Missouri.d6058818.Car-Rental-Guide)[Northeast Missouri Vacation Packages](https://expedia.com/Northeast-Missouri.d6058818.Destination-Travel-Guides) # Northeast Missouri, MO ## Travel Guide ![This is a cool place to visit back in my home town of Kirkwood MO. The sculptures here are amazing. Which reminds me, I need to plan a trip back home sometime soon lol. ](https://images.trvl-media.com/place/10540/802bf5d7-a3f6-4e16-b933-40ae5b4ec325.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![This is a cool place to visit back in my home town of Kirkwood MO. The sculptures here are amazing. Which reminds me, I need to plan a trip back home sometime soon lol. ](https://images.trvl-media.com/place/10540/802bf5d7-a3f6-4e16-b933-40ae5b4ec325.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![#church](https://images.trvl-media.com/place/3284/71f0fe58-38e6-456f-b369-f96ad38aa8a7.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Cathedral Basilica of St. Louis](https://images.trvl-media.com/place/3284/bc5d11c2-24db-459d-89bb-fab5b5982f79.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Water lily at botanical garden at St. Louis Mo ](https://images.trvl-media.com/place/3284/dca282b8-0c71-4b21-8675-486822ff34fb.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Northeast Missouri Where to stay Things to do ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=DX_SPRING_PROMO_6058818) ### Where to stay in Northeast Missouri ![St. Louis Missouri](https://images.trvl-media.com/place/6058846/ad61b28c-fc90-4997-9e8c-7d09999a125f.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Clayton Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station. [](https://expedia.com/St-Louis-Clayton.dx6058846) ![St. Louis](https://images.trvl-media.com/place/6272/26979a45-e5a8-4066-9ddd-1ba301b4bd4a.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Berkeley Visitors highly recommend Berkeley for its abundant dining options, and you can make a stop by James S. McDonnell Prologue Room while you're in town. [](https://expedia.com/St-Louis-Berkeley.dx6272) ![Love this hotel.](https://images.trvl-media.com/place/3284/7d953ffd-a093-422e-8101-35af3b9eb6fc.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Downtown West If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing. [](https://expedia.com/St-Louis-Downtown-West.dx553248635976473134) ![Central West End](https://images.trvl-media.com/place/6175135/a1a4060c-5623-4543-941c-91e3f85f02cc.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Central West End Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis. [](https://expedia.com/St-Louis-Central-West-End.dx6175135) ![Soulard](https://images.trvl-media.com/place/553248634993813110/772699ae-c004-41dd-b7b2-699b703bad53.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Soulard You'll enjoy the bars and churches in Soulard. You might want to make time for a stop at Anheuser-Busch Brewery or Soulard Farmer's Market. [](https://expedia.com/St-Louis-Soulard.dx553248634993813110) ![Creve Coeur Lake, Saint Louis, Missouri Fall Season](https://images.trvl-media.com/place/7717/99c4d9ff-92a3-4e6a-85fa-a8b0fe6fb3f3.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Creve Coeur Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town. [](https://expedia.com/St-Louis-Creve-Coeur.dx7717) [See our Where To Stay guide](https://expedia.com/Northeast-Missouri.dx6058818.Where-To-Stay?rfrr=TG.LP.Dest.Neighborhoods) - Northeast Missouri Hotel Deals - Vacation Rentals in Northeast Missouri ![Pear Tree Inn St. Louis Near Union Station](https://images.trvl-media.com/lodging/1000000/30000/26600/26572/3056142b_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Pear Tree Inn St. Louis Near Union Station 2211 Market Street St. Louis MO $106 nightly $124 total Apr 5 - Apr 6 Total with taxes and fees Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ... 8.8/10 Excellent! (1,862 reviews) Everyone and everything was amazing!! Definitely would recommend and stay again. Reviewed on Mar 11, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F5%2F2026&endDate=4%2F6%2F2026&selected=26572&PinnedHotelID=26572&HadPinnedHotel=true®ionId=6058818) ![Clayton Plaza Hotel & Extended Stay](https://images.trvl-media.com/lodging/1000000/20000/18200/18144/5c61cbf8_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Clayton Plaza Hotel & Extended Stay 7750 Carondelet Avenue St. Louis MO $100 nightly $116 total Apr 12 - Apr 13 Total with taxes and fees Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ... 8.8/10 Excellent! (3,103 reviews) This is an older property, but very clean, comfortable, spacious and convenient to downtown Clayton. Parking was convenient and free on the weekend. Breakfast was better than average, with chef-made omelets and waffles. Reviewed on Mar 11, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F12%2F2026&endDate=4%2F13%2F2026&selected=18144&PinnedHotelID=18144&HadPinnedHotel=true®ionId=6058818) ![21C Museum Hotel St Louis ](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/bd7064dc_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### 21C Museum Hotel St Louis 1528 Locust street St. Louis MO $131 nightly $153 total Apr 5 - Apr 6 Total with taxes and fees Book a stay at this luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ... 9/10 Wonderful! (1,648 reviews) Such a cool hotel I love the museum on the second floor so interesting and all the penguins food is great restaurants great everything just what a great stay very unique but very quiet very cozy love everything about it. Can’t wait to stay at the other ones. Reviewed on Mar 11, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F5%2F2026&endDate=4%2F6%2F2026&selected=89164592&PinnedHotelID=89164592&HadPinnedHotel=true®ionId=6058818) [See all 2,886 properties in Northeast Missouri](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=3%2F13%2F2026&endDate=3%2F14%2F2026®ionId=6058818) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![ White House at Grand Central](https://images.trvl-media.com/lodging/84000000/83130000/83121100/83121050/f3c125ad_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### White House at Grand Central 3805 Lindell Blvd St. Louis MO Stay at this apartment in St. Louis. Enjoy free WiFi, a 24-hour front desk, and a garden. Popular attractions St. Louis Union Station and Busch Stadium are located ... [](https://expedia.com/St-Louis-Hotels-Grand-Center-Apartments.h83121050.Hotel-Information) ![Centrally located in the Tower Grove East neighborhood!](https://images.trvl-media.com/lodging/39000000/38730000/38727900/38727815/fb0dcfca_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Centrally located in the Tower Grove East neighborhood! St. Louis MO Stay at this vacation home in St. Louis. Enjoy laundry facilities, an in-room coffeemaker, and air conditioning. Popular attractions St. Louis Union Station ... 9.8/10 Exceptional! (144 reviews) Cute home and theme/decor! We had a very pleasant stay and learned a lot about the state fair. Keypad entry made it convenient to "check in" and the host answered our questions quickly! The house it's self was clean and comfortable. The only feedback I have is that the house was rather dusty. Reviewed on Mar 2, 2026 [](https://expedia.com/St-Louis-Hotels-Centrally-Located-In-The-Tower-Grove-East-Neighborhood.h38727815.Hotel-Information) ![St. Charles 1860's Gem - Sleeps 6!](https://images.trvl-media.com/lodging/35000000/34490000/34480500/34480442/8ece9774_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### St. Charles 1860's Gem - Sleeps 6! St Charles MO Book a stay at this family-friendly vacation home in St. Charles. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Ameristar Casino St. ... 9.8/10 Exceptional! (143 reviews) Clean house, everything worked, great location Reviewed on Feb 26, 2026 [](https://expedia.com/St-Louis-Hotels-St-Charles-1860s-Gem.h34480442.Hotel-Information) [See all properties in Northeast Missouri](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=6058818&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Northeast Missouri hotel availability [Tonight ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058818&startDate=2026-03-12&endDate=2026-03-13)[Mar 12 - Mar 13](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058818&startDate=2026-03-12&endDate=2026-03-13) [Tomorrow night ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058818&startDate=2026-03-13&endDate=2026-03-14)[Mar 13 - Mar 14](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058818&startDate=2026-03-13&endDate=2026-03-14) [This weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058818&startDate=3%2F13%2F2026&endDate=3%2F15%2F2026)[Mar 13 - Mar 15](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058818&startDate=3%2F13%2F2026&endDate=3%2F15%2F2026) [Next weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058818&startDate=3%2F20%2F2026&endDate=3%2F22%2F2026)[Mar 20 - Mar 22](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058818&startDate=3%2F20%2F2026&endDate=3%2F22%2F2026) ### Popular places to visit ![Union Station, St. Louis, MO](https://images.trvl-media.com/place/502868/8704491b-9324-4c56-89ed-94a638702313.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St. Louis Union Station 4/5(615 reviews) You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's great live music or attend a baseball game. [](https://expedia.com/St-Louis-Union-Station-Downtown-West.d502868.Vacation-Attraction) ![St. Louis Cardinals Baseball. ](https://images.trvl-media.com/place/3284/67189e41-0060-455b-85a9-ab65c9125a63.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Busch Stadium 4.5/5(1,469 reviews) Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed theater scene or attend a baseball game. [](https://expedia.com/Busch-Stadium-Downtown-St-Louis.d502872.Vacation-Attraction) ![Aerial view of vibrant downtown St. Louis with Enterprise Center and St. Louis Wheel, St. Louis, Missouri, United States.](https://images.trvl-media.com/place/502873/da730472-6151-40a1-b074-013a6c50d0f4.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Enterprise Center 4.5/5(491 reviews) Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's great live music or attend a baseball game. [](https://expedia.com/Enterprise-Center-Downtown-West.d502873.Vacation-Attraction) ![Forest Park showing flowers, a garden and modern architecture](https://images.trvl-media.com/place/553248635823456129/8a0353b6-e0c6-4e86-b04a-b6ff6d82d7ea.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Forest Park 4.5/5(1,050 reviews) Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit. [](https://expedia.com/Forest-Park-St-Louis.d6005687.Vacation-Attraction) ![St. Louis Zoo](https://images.trvl-media.com/place/502878/51adfd0a-5175-4aa9-aa40-2221835ea3ae.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St. Louis Zoo 4.5/5(1,212 reviews) In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world. [](https://expedia.com/St-Louis-Zoo-St-Louis.d502878.Vacation-Attraction) ![St. Louis, Missouri - 08.22.2021 - Brookings Hall on the Danforth Campus of Washington University in St. Louis.](https://images.trvl-media.com/place/502876/30a14638-e6de-4f99-9bb4-fcc8ce569bb3.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Washington University in St. Louis 4.5/5(479 reviews) Enjoy the collegiate vibe at Washington University in St. Louis during your stay in St. Louis. Amble around the area's lush forest or attend a sporting event. [](https://expedia.com/Washington-University-In-St-Louis-Clayton.d502876.Vacation-Attraction) ### Things to do ![Kansas City: Kansas City Tap Tour](https://mediaim.expedia.com/localexpert/48196637/8368eb46-dcaf-414e-968d-ef44f60b8150.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Kansas City: Kansas City Tap Tour $5 per adult [](https://expedia.com/things-to-do/kansas-city-kansas-city-tap-tour.a48196637.activity-details) ![ Kansas City MO Attractions Pass](https://mediaim.expedia.com/localexpert/48553911/a49508b8-4088-4f02-b62a-6d2187d4f790.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Kansas City MO Attractions Pass $30 per adult [](https://expedia.com/things-to-do/kansas-city-mo-attractions-pass.a48553911.activity-details) ![Tom’s Town Distilling Co., the first legal distillery in downtown KC since Prohibition, produces premium craft spirits including award-winning Bourbon, Gin, Barreled Gin and Vodka.](https://mediaim.expedia.com/localexpert/1000934/4c1cd67d-b986-4959-9e34-de616c8e0852.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Tom's Town Distillery Tour and Tasting $27 per adult **100%** of travellers recommend [](https://expedia.com/things-to-do/toms-town-distillery-tour-and-tasting.a1000934.activity-details) ![Welcome to Kansas City Streetcar Tour](https://mediaim.expedia.com/localexpert/51211888/7a68dc7b-13ee-47df-97c7-fd9ec6601262.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Welcome to Kansas City Streetcar Tour $65 per adult [](https://expedia.com/things-to-do/welcome-to-kansas-city-streetcar-tour.a51211888.activity-details) ![Kansas City: Country Club Plaza Escape Game](https://mediaim.expedia.com/localexpert/48325406/122955a9-8eb9-499b-8503-539e9b657051.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Kansas City: Country Club Plaza Escape Game $43 per adult [](https://expedia.com/things-to-do/kansas-city-country-club-plaza-escape-game.a48325406.activity-details) ![Small-Group Jewelry Making with Wine Tasting in Kansas City](https://mediaim.expedia.com/localexpert/4280014/0d49758a-4327-488c-a2c6-a1c8287c7624.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Small-Group Jewelry Making with Wine Tasting in Kansas City $59 per adult [](https://expedia.com/things-to-do/small-group-jewelry-making-with-wine-tasting-in-kansas-city.a4280014.activity-details) [See all activities in Northeast Missouri](https://expedia.com/Things-To-Do-In-Northeast-Missouri.d6058818.Travel-Guide-Activities) ## Cities near Northeast Missouri ![Thousand Hill State Park](https://images.trvl-media.com/place/1630/fc722898-84e8-4e1a-b266-b1ca1d792625.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Kirksville ![Gateway Arch which includes a monument, a sunset and a city](https://images.trvl-media.com/place/502855/5f501368-a6cd-4154-9de4-4f7a5e79516f.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### St. Louis ![Boston Quincy Marchet and Custom House tower](https://images.trvl-media.com/place/3622/3cdc0cdf-5fd1-4898-8330-39bf5d3131ca.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Quincy ![Aerial view of the city of Hannibal in Missouri from Lovers Leap overlook with Mississippi River and cruise boat](https://images.trvl-media.com/place/6068/0745fe01-80e8-4dd7-979d-f7342ba3c9e4.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Hannibal ## Explore a world of travel with Expedia - 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[Macon Vacation Rentals ](https://www.expedia.com/Macon-Vacation-Rentals.d6058819.Travel-Guide-VacationRentals) - Cities near Northeast Missouri - Places of interest [Kirksville](https://expedia.com/Kirksville.dx1630)[St. Louis](https://expedia.com/St-Louis.dx178309)[Quincy](https://expedia.com/Quincy.dx3622)[Hannibal](https://expedia.com/Hannibal.dx6068)[Alton](https://expedia.com/Alton.dx6108)[Cuba](https://expedia.com/Cuba.dx6499)[Sullivan](https://expedia.com/Sullivan.dx6987)[Eureka](https://expedia.com/Eureka.dx7020)[Bridgeton](https://expedia.com/Bridgeton.dx7043)[St. Ann](https://expedia.com/St-Ann.dx7051)[Fenton](https://expedia.com/Fenton.dx7150)[Canton](https://expedia.com/Canton.dx7238)[Maryland Heights](https://expedia.com/Maryland-Heights.dx7347)[Webster Groves](https://expedia.com/Webster-Groves.dx7660)[Wentzville](https://expedia.com/Wentzville.dx7679)[Frontenac](https://expedia.com/Frontenac.dx7960)[Granite City](https://expedia.com/Granite-City.dx8015)[Florissant](https://expedia.com/Florissant.dx8104)[Kirkwood](https://expedia.com/Kirkwood.dx8470)[Monroe City](https://expedia.com/Monroe-City.dx8694)[Moberly](https://expedia.com/Moberly.dx8708)[Mexico](https://expedia.com/Mexico.dx8832)[Pacific](https://expedia.com/Pacific.dx9043)[Chesterfield](https://expedia.com/Chesterfield.dx9530)[St. Charles](https://expedia.com/St-Charles.dx9786) - 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