Title: San Ysidro Vacation Rentals from $114: Search Short-Term Rentals | Expedia.com [San Ysidro Travel Guide](https://expedia.com/San-Ysidro.dx8380)[Hotels in San Ysidro](https://expedia.com/San-Ysidro-Hotels.d8380.Travel-Guide-Hotels)[Flights to San Ysidro](https://expedia.com/Cheap-Flights-To-San-Ysidro.d8380.Travel-Guide-Flights)[Things to do in San Ysidro](https://expedia.com/Things-To-Do-In-San-Ysidro.d8380.Travel-Guide-Activities)[Car Rentals in San Ysidro](https://expedia.com/Car-Rentals-In-San-Ysidro.d8380.Car-Rental-Guide)[San Ysidro Vacation Packages](https://expedia.com/San-Ysidro.d8380.Destination-Travel-Guides) ![A fence on the United States - Mexico border where it meets the Pacific Ocean in Border Field State Park Beach](https://images.trvl-media.com/place/8380/3ab13fe2-f1be-465b-bd43-6d314810f387.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/8380/3ab13fe2-f1be-465b-bd43-6d314810f387.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_bundle_and_save.svg) ### Bundle & Save Get more, spend less whenever you see Bundle & Save deals - ![](https://a.travel-assets.com/travel-assets-manager/pictograms-expedia/light__onekey.svg) ### OneKeyCash Earn OneKeyCash on all your eligible bookings - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_ftc.svg) ### Upfront pricing We are not like the others - we include taxes and fees ## Check prices for these dates In two weeks [Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=8380&startDate=2026-03-27&endDate=2026-03-29&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [May 8 - May 10](https://www.expedia.com/Hotel-Search?regionId=8380&startDate=2026-05-08&endDate=2026-05-10&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [Jun 5 - Jun 7](https://www.expedia.com/Hotel-Search?regionId=8380&startDate=2026-06-05&endDate=2026-06-07&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [Jul 3 - Jul 5](https://www.expedia.com/Hotel-Search?regionId=8380&startDate=2026-07-03&endDate=2026-07-05&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for San Ysidro vacation rentals ![Rooftop terrace](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/dd5fc603.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/6521c599.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![55-inch flat-screen TV with cable channels, Netflix, Hulu](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/4123f91e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/9a181764.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sentral Gaslamp Quarter [](https://www.expedia.com/San-Diego-Hotels-Sentral-Gaslamp-Quarter.h114116366.Hotel-Information) Downtown San Diego 9.4/10 Exceptional (764 reviews) "Great room had a great time very quiet and nice hotel lovely View" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tyrell $143 nightly $166 total Mar 19 - Mar 20 Total with taxes and fees [](https://www.expedia.com/San-Diego-Hotels-Sentral-Gaslamp-Quarter.h114116366.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/121000000/120340000/120338500/120338477/f986cbb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/121000000/120340000/120338500/120338477/6e59af84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/121000000/120340000/120338500/120338477/a98893c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/121000000/120340000/120338500/120338477/9ff1d7f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Terrific studio in Chula Vista with cozy vibes [](https://www.expedia.com/Chula-Vista-Hotels-Terrific-Studio-In-Chula-Vista-With-Cozy-Vibes.h120338477.Hotel-Information) Chula Vista 9.0/10 Wonderful (8 reviews) "Great location. Great owners " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) INGRID R. $132 nightly $143 total Apr 13 - Apr 14 Total with taxes and fees [](https://www.expedia.com/Chula-Vista-Hotels-Terrific-Studio-In-Chula-Vista-With-Cozy-Vibes.h120338477.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/38000000/37020000/37014000/37013939/6dd046c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/38000000/37020000/37014000/37013939/596ef00a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/38000000/37020000/37014000/37013939/cd12e163.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/38000000/37020000/37014000/37013939/c75aad92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spring Sale in Bettie Blue RV fun! [](https://www.expedia.com/El-Cajon-Hotels-Flashback-Family-Fun-At-The-Retro-RV-Adventure-Glamp-In-Style-In-Bettie-Blue.h37013939.Hotel-Information) El Cajon 9.8/10 Exceptional (16 reviews) "We came down to Cali to get away from the Canadian cold and this little place was perfect for our family of three. Great location , cozy comfy Christmas for us :) " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Niki P. $174 nightly $190 total Apr 13 - Apr 14 Total with taxes and fees [](https://www.expedia.com/El-Cajon-Hotels-Flashback-Family-Fun-At-The-Retro-RV-Adventure-Glamp-In-Style-In-Bettie-Blue.h37013939.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/f051791c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/e8d02919.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Room, 1 Queen Bed (East - Freeway Facing) | Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/61427440.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/b278e0ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Uptown Inn by Vantaggio - Limited Service Apart-Hotel [](https://www.expedia.com/San-Diego-Hotels-Uptown-Inn.h104283827.Hotel-Information) Hillcrest 8.4/10 Very Good (314 reviews) "I had a great visit. Rooms were clean. Beautiful area. Amazing view from the patio. Polite staff. I will definitely stay again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Harold $101 nightly $114 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/San-Diego-Hotels-Uptown-Inn.h104283827.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/850000/842000/841962/ae7c0c5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach nearby](https://images.trvl-media.com/lodging/1000000/850000/842000/841962/176e7c12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/850000/842000/841962/46a9ae00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/850000/842000/841962/31020b74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Coronado Beach Resort [](https://www.expedia.com/Coronado-Hotels-Coronado-Beach-Resort.h841962.Hotel-Information) Glorietta Bay 9.0/10 Wonderful (775 reviews) "Excellent location, clean and cozy" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Oksana $229 nightly $252 total Mar 26 - Mar 27 Total with taxes and fees [](https://www.expedia.com/Coronado-Hotels-Coronado-Beach-Resort.h841962.Hotel-Information) ![Smart TV](https://images.trvl-media.com/lodging/109000000/108600000/108593500/108593412/41d1b5c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/109000000/108600000/108593500/108593412/170fbed5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/109000000/108600000/108593500/108593412/02c10b6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/109000000/108600000/108593500/108593412/1a83191a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 'Ted' 2-bedroom cozy house in central location! 10 minutes to Balboa! [](https://www.expedia.com/San-Diego-Hotels-Ted-2-Bedroom-Cozy-House-In-Central-Location-10-Minutes-To-Balboa.h108593412.Hotel-Information) Encanto 8.6/10 Excellent (31 reviews) "This was a good central location and convenient to all of San Diego, both in and out of town." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Samuel B. $211 nightly $235 total Mar 18 - Mar 19 Total with taxes and fees [](https://www.expedia.com/San-Diego-Hotels-Ted-2-Bedroom-Cozy-House-In-Central-Location-10-Minutes-To-Balboa.h108593412.Hotel-Information) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/43000000/42220000/42216600/42216597/1eed4776.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/43000000/42220000/42216600/42216597/0b4c491f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/43000000/42220000/42216600/42216597/d8380160.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/43000000/42220000/42216600/42216597/f65a9555.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy Private Studio in El Cajon [](https://www.expedia.com/El-Cajon-Hotels-Cozy-Private-Studio-In-El-Cajon.h42216597.Hotel-Information) Mount Helix 8.6/10 Excellent (20 reviews) "Sergio was very responsive and helpful. The suite was clean and comfortable. We had a very pleasant stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tanya N. $97 nightly $97 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/El-Cajon-Hotels-Cozy-Private-Studio-In-El-Cajon.h42216597.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/17900/17865/f34abdc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/20000/17900/17865/03c11edc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/20000/17900/17865/41d4439d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/1000000/20000/17900/17865/97d1106b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott Vacation Club®, San Diego [](https://www.expedia.com/San-Diego-Hotels-Marriott-Vacation-Club-Pulse.h17865.Hotel-Information) Downtown San Diego 9.4/10 Exceptional (1,031 reviews) "Great place to stay!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Rose Marie JOy $161 nightly $186 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/San-Diego-Hotels-Marriott-Vacation-Club-Pulse.h17865.Hotel-Information) ![House (5 Bedrooms) | Interior](https://images.trvl-media.com/lodging/105000000/104960000/104953900/104953896/0166b5d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (5 Bedrooms) | Interior](https://images.trvl-media.com/lodging/105000000/104960000/104953900/104953896/ac03dc6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (5 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/105000000/104960000/104953900/104953896/bb1b86f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (5 Bedrooms) | Interior](https://images.trvl-media.com/lodging/105000000/104960000/104953900/104953896/850dc339.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fireplace, Hot Tub, Patio & Bbq: San Diego Home [](https://www.expedia.com/Spring-Valley-Hotels-Spacious-Spring-Valley-Home-W-Fenced-Yard-Grill.h104953896.Hotel-Information) Spring Valley $695 nightly $748 total Mar 16 - Mar 17 Total with taxes and fees [](https://www.expedia.com/Spring-Valley-Hotels-Spacious-Spring-Valley-Home-W-Fenced-Yard-Grill.h104953896.Hotel-Information) ![Smart TV](https://images.trvl-media.com/lodging/96000000/95390000/95389400/95389365/d49b1213.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/96000000/95390000/95389400/95389365/e3faab8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/96000000/95390000/95389400/95389365/eb2bfff0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/96000000/95390000/95389400/95389365/60d36bbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casita Sol - Bright Modern Private 10 mins to downtown [](https://www.expedia.com/National-City-Hotels-Casita-Sol-Bright-Modern-Private-10-Mins-To-Downtown.h95389365.Hotel-Information) National City 10/10 Exceptional (8 reviews) "Very cute home, I definitely enjoyed the stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lena \_. $212 nightly $212 total Mar 17 - Mar 18 Total with taxes and fees [](https://www.expedia.com/National-City-Hotels-Casita-Sol-Bright-Modern-Private-10-Mins-To-Downtown.h95389365.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/108000000/107770000/107764300/107764239/w1199h799x1y1-12fbdf79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/108000000/107770000/107764300/107764239/882b7878.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, WiFi](https://images.trvl-media.com/lodging/108000000/107770000/107764300/107764239/36e9744e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/108000000/107770000/107764300/107764239/w1200h798x0y1-dc816a39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxury Studio with Lake Views and Spacious Balcony [](https://www.expedia.com/Spring-Valley-Hotels-Modern-Lakeview-Studio-W-Patio.h107764239.Hotel-Information) Spring Valley 7.4/10 Good (6 reviews) "It was beautiful and very modern. We loved it and hope to come back again!! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ronette B. $194 nightly $201 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Spring-Valley-Hotels-Modern-Lakeview-Studio-W-Patio.h107764239.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/116000000/115500000/115493800/115493795/550a0cce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/116000000/115500000/115493800/115493795/d7d47447.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/116000000/115500000/115493800/115493795/cbdc95fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, hair dryer, towels, soap](https://images.trvl-media.com/lodging/116000000/115500000/115493800/115493795/w1618h1074x1y0-0ab1b786.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Mesa Family Retreat - 20 minutes to Beaches & More! [](https://www.expedia.com/San-Diego-Hotels-La-Mesa-Family-Retreat-20-Minutes-To-Beaches-More.h115493795.Hotel-Information) La Mesa 8.8/10 Excellent (6 reviews) "House was nice but my husband needed accessible entry and areas around the dining and living room area. The rooms were nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Margaret $621 nightly $621 total Apr 14 - Apr 15 Total with taxes and fees [](https://www.expedia.com/San-Diego-Hotels-La-Mesa-Family-Retreat-20-Minutes-To-Beaches-More.h115493795.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/97000000/96500000/96499900/96499822/16265a3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/97000000/96500000/96499900/96499822/565f7fab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/97000000/96500000/96499900/96499822/0aaf96ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/97000000/96500000/96499900/96499822/e99431d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Casita Guest House, private fenced yard & with heat and AC, pet friendly [](https://www.expedia.com/Spring-Valley-Hotels-La-Casita-Guest-House-With-Fenced-Yard-Pets-Ok.h96499822.Hotel-Information) Mount Helix 9.6/10 Exceptional (10 reviews) "Host and amenities were both very nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Juergen S. $297 nightly $305 total Apr 13 - Apr 14 Total with taxes and fees [](https://www.expedia.com/Spring-Valley-Hotels-La-Casita-Guest-House-With-Fenced-Yard-Pets-Ok.h96499822.Hotel-Information) ![Fridge, oven, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/107000000/106240000/106238400/106238388/e6fd97be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, free WiFi, bed sheets, wheelchair access](https://images.trvl-media.com/lodging/107000000/106240000/106238400/106238388/ad6c035d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/107000000/106240000/106238400/106238388/0cd79178.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/107000000/106240000/106238400/106238388/ea24846b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### NEW Peaceful Studio Unit - 3 Blocks from the beach [](https://www.expedia.com/San-Diego-Hotels-NEW-Peaceful-Studio-Unit-3-Blocks-From-The-Beach.h106238388.Hotel-Information) Ocean Beach 9.8/10 Exceptional (13 reviews) "Great location and accommodations." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kecia $280 nightly $311 total Mar 17 - Mar 18 Total with taxes and fees [](https://www.expedia.com/San-Diego-Hotels-NEW-Peaceful-Studio-Unit-3-Blocks-From-The-Beach.h106238388.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/119000000/118140000/118135400/118135358/42129fed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books](https://images.trvl-media.com/lodging/119000000/118140000/118135400/118135358/0d497d37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/119000000/118140000/118135400/118135358/5ead5db7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/119000000/118140000/118135400/118135358/d4d5cd6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 3-bedroom house in lovely San Diego with garage. Enjoy your stay [](https://www.expedia.com/El-Cajon-Hotels-3-Bedroom-House-In-Lovely-San-Diego-With-Garage-Enjoy-Your-Stay.h118135358.Hotel-Information) El Cajon 10/10 Exceptional (3 reviews) "Clean rooms, everything was accurate as it was described in the description. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Virgilio Alan A. $378 nightly $412 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/El-Cajon-Hotels-3-Bedroom-House-In-Lovely-San-Diego-With-Garage-Enjoy-Your-Stay.h118135358.Hotel-Information) ![Deluxe 2 King Bedrooms, Multiple Beds, Sleeps 11ppl | Terrace/patio](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/6ef835b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/6c7bbd52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/1b9a69bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/333bf268.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### City24 Hotel Little Italy Mission Hills [](https://www.expedia.com/San-Diego-Hotels-City24-Hotel-Little-Italy-Mission-Hill.h104140458.Hotel-Information) Middletown 9.6/10 Exceptional (128 reviews) "Clean nice place to stay at" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Luis $186 nightly $210 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/San-Diego-Hotels-City24-Hotel-Little-Italy-Mission-Hill.h104140458.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/45000000/44260000/44250700/44250669/w1024h676x0y4-f444e85c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/45000000/44260000/44250700/44250669/w1020h683x4y0-c6bc8259.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/45000000/44260000/44250700/44250669/a143454e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/45000000/44260000/44250700/44250669/952dcf05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Private Cozy Clean, close to EVERYTHING [](https://www.expedia.com/San-Diego-Hotels-Private-Cozy-Clean.h44250669.Hotel-Information) Mid-City 9.8/10 Exceptional (57 reviews) "The place is cute and close to everything. David was great!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) LuAnne A. $390 nightly $435 total Mar 30 - Mar 31 Total with taxes and fees [](https://www.expedia.com/San-Diego-Hotels-Private-Cozy-Clean.h44250669.Hotel-Information) ![Beach nearby](https://images.trvl-media.com/lodging/120000000/119490000/119481800/119481708/14265a3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/120000000/119490000/119481800/119481708/59c0f3d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/120000000/119490000/119481800/119481708/14df5a88_edited_1688.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/120000000/119490000/119481800/119481708/839e6f2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 3BR - 3Bth near San Diego Gaslamp Beach [](https://www.expedia.com/National-City-Hotels-Modern-3-Bed-3-Bath-Near-San-Diego-Gaslamp-Beach.h119481708.Hotel-Information) National City 10/10 Exceptional (3 reviews) "It was lovely!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sandi S. $320 nightly $348 total Mar 18 - Mar 19 Total with taxes and fees [](https://www.expedia.com/National-City-Hotels-Modern-3-Bed-3-Bath-Near-San-Diego-Gaslamp-Beach.h119481708.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/119000000/118710000/118709500/118709433/e47b3d2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/119000000/118710000/118709500/118709433/76e6d045.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/119000000/118710000/118709500/118709433/8f2fc806.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/119000000/118710000/118709500/118709433/858d7188.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### CLOSE TO EVERYTHING FUN - Charming 2-BR /2 BA house in San Diego WiFi AC parking [](https://www.expedia.com/San-Diego-Hotels-CLOSE-TO-EVERYTHING-FUN-Charming-2-BR-2-BA-House-In-San-Diego-WiFi-AC-Parking.h118709433.Hotel-Information) Mid-City 10/10 Exceptional (8 reviews) "It was easy to book and check in." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James D. $370 nightly $411 total Apr 13 - Apr 14 Total with taxes and fees [](https://www.expedia.com/San-Diego-Hotels-CLOSE-TO-EVERYTHING-FUN-Charming-2-BR-2-BA-House-In-San-Diego-WiFi-AC-Parking.h118709433.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/70000000/69870000/69867200/69867132/ae9ed2ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/70000000/69870000/69867200/69867132/83b9edc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/70000000/69870000/69867200/69867132/f27318eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/70000000/69870000/69867200/69867132/77078036.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Viva Pacifica - Right in the Heart of ALL the fun! [](https://www.expedia.com/San-Diego-Hotels-Viva-Pacifica-Right-In-The-Heart-Of-ALL-The-Fun.h69867132.Hotel-Information) North Park 9.2/10 Wonderful (17 reviews) "The location was perfect, we walked all over the place. We were able to walk to the zoo, I highly recommend it! The place was perfect for us and the patio and outdoor space was great for coffee in the morning. I will definitely stay here again! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) kelly g. $379 nightly $421 total Mar 16 - Mar 17 Total with taxes and fees [](https://www.expedia.com/San-Diego-Hotels-Viva-Pacifica-Right-In-The-Heart-Of-ALL-The-Fun.h69867132.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-28&endDate=2026-03-29®ionId=8380&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=VR_SPRING_PROMO_8380) ## Find vacation rentals that suit your style Aparthotels [](https://www.expedia.com/Hotel-Search?destination=San+Ysidro%2C+California%2C+United+States+of+America®ionId=8380&latLong=32.552001%2C-117.043081&adults=2&startDate=2026-06-11&d1=2026-06-11&endDate=2026-06-14&d2=2026-06-14&lodging=APART_HOTEL) Private vacation homes [](https://www.expedia.com/Hotel-Search?destination=San+Ysidro%2C+California%2C+United+States+of+America®ionId=8380&latLong=32.552001%2C-117.043081&adults=2&startDate=2026-06-11&d1=2026-06-11&endDate=2026-06-14&d2=2026-06-14&lodging=VACATION_HOME) Villas [](https://www.expedia.com/Hotel-Search?destination=San+Ysidro%2C+California%2C+United+States+of+America®ionId=8380&latLong=32.552001%2C-117.043081&adults=2&startDate=2026-06-11&d1=2026-06-11&endDate=2026-06-14&d2=2026-06-14&lodging=VILLA) Condos [](https://www.expedia.com/Hotel-Search?destination=San+Ysidro%2C+California%2C+United+States+of+America®ionId=8380&latLong=32.552001%2C-117.043081&adults=2&startDate=2026-06-11&d1=2026-06-11&endDate=2026-06-14&d2=2026-06-14&lodging=CONDO) Apartments [](https://www.expedia.com/Hotel-Search?destination=San+Ysidro%2C+California%2C+United+States+of+America®ionId=8380&latLong=32.552001%2C-117.043081&adults=2&startDate=2026-06-11&d1=2026-06-11&endDate=2026-06-14&d2=2026-06-14&lodging=APARTMENT) Cottages [](https://www.expedia.com/Hotel-Search?destination=San+Ysidro%2C+California%2C+United+States+of+America®ionId=8380&latLong=32.552001%2C-117.043081&adults=2&startDate=2026-06-11&d1=2026-06-11&endDate=2026-06-14&d2=2026-06-14&lodging=COTTAGE) Cabins [](https://www.expedia.com/Hotel-Search?destination=San+Ysidro%2C+California%2C+United+States+of+America®ionId=8380&latLong=32.552001%2C-117.043081&adults=2&startDate=2026-06-11&d1=2026-06-11&endDate=2026-06-14&d2=2026-06-14&lodging=CABIN) Houseboats [](https://www.expedia.com/Hotel-Search?destination=San+Ysidro%2C+California%2C+United+States+of+America®ionId=8380&latLong=32.552001%2C-117.043081&adults=2&startDate=2026-06-11&d1=2026-06-11&endDate=2026-06-14&d2=2026-06-14&lodging=HOUSE_BOAT) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSan-Ysidro-Vacation-Rentals.d8380.Travel-Guide-VacationRentals)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSan-Ysidro-Vacation-Rentals.d8380.Travel-Guide-VacationRentals) ## Top San Ysidro Hotel Reviews ![Hard Rock Hotel San Diego](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/7e147d0f_y.jpg) ### Hard Rock Hotel San Diego 10/10 Excellent "Comfortable and a creative atmosphere. " [](https://expedia.com/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) ![The Sofia Hotel](https://images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/bd726404_y.jpg) ### The Sofia Hotel 6/10 Okay "Room was clean & customer service was incredible. Shower water was cold but the staff is so nice that I’m sure they’d address the sure if you present it to them. I only stayed one night " [](https://expedia.com/San-Diego-Hotels-The-Sofia-Hotel.h1573807.Hotel-Information) ![Days Inn by Wyndham San Diego Hotel Circle](https://images.trvl-media.com/lodging/1000000/20000/19300/19220/c491024e_y.jpg) ### Days Inn by Wyndham San Diego Hotel Circle 8/10 Good "Nice staff " [](https://expedia.com/San-Diego-Hotels-Days-Inn-By-Wyndham-San-Diego-Hotel-Circle.h19220.Hotel-Information) ![Omni San Diego Hotel at the Ballpark](https://images.trvl-media.com/lodging/1000000/990000/982500/982408/029abbb9_y.jpg) ### Omni San Diego Hotel at the Ballpark 10/10 Excellent "Clean rooms, great staff, great pool." [](https://expedia.com/San-Diego-Hotels-Omni-San-Diego-Hotel.h982408.Hotel-Information) ![San Diego Mission Bay Resort](https://images.trvl-media.com/lodging/1000000/30000/25600/25598/b5f2a64d_y.jpg) ### San Diego Mission Bay Resort 10/10 Excellent "Wonderful place to just stay and not go any where else nice small resort" [](https://expedia.com/San-Diego-Hotels-San-Diego-Mission-Bay-Resort.h25598.Hotel-Information) ![Bay Club Hotel & Marina](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/4003f7ef_y.jpg) ### Bay Club Hotel & Marina 10/10 Excellent "Everything is nice. The property is super old though and should probably be completely renovated, but I had a blast." [](https://expedia.com/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information) ![Best Western Seven Seas](https://images.trvl-media.com/lodging/1000000/10000/1800/1734/w3837h2556x3y3-8b148daf_y.jpg) ### Best Western Seven Seas 10/10 Excellent "Family friendly. Restaurant was delicious. friendly staff" [](https://expedia.com/San-Diego-Hotels-Best-Western-Seven-Seas.h1734.Hotel-Information) ![The DEXTRO Little Italy, BW Premier Collection](https://images.trvl-media.com/lodging/1000000/180000/170400/170338/6fe441dd_y.jpg) ### The DEXTRO Little Italy, BW Premier Collection 6/10 Okay "The staff was knowledgeable and friendly. The hotel was clean. The room was basic. It had a fridge but no microwave. It's walking distance many restaurants and the piers. It's also convenient to get th Balboa Park and the airport." [](https://expedia.com/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego-Downtown-Little-Italy.h170338.Hotel-Information) ![Manchester Grand Hyatt San Diego](https://images.trvl-media.com/lodging/1000000/20000/12100/12073/4b74daf8_y.jpg) ### Manchester Grand Hyatt San Diego 10/10 Excellent "Perfect service " [](https://expedia.com/San-Diego-Hotels-Manchester-Grand-Hyatt-San-Diego.h12073.Hotel-Information) ## Find out more about San Ysidro **Everything you need to know about San Ysidro vacation rentals** Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the San Ysidro vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on. There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect San Ysidro vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. **San Ysidro vacation rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in San Ysidro. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit San Ysidro in high season. Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $114 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals! **How to find incredible deals on San Ysidro rentals** At Expedia, we put the best San Ysidro vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. To find some top San Ysidro rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream San Ysidro vacation. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around San Ysidro. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. ## Explore a world of travel with Expedia - Trending destinations on Expedia.com - All accommodation types in San Ysidro ### Trending destinations on Expedia.com - [Destin Vacation Rentals ](https://www.expedia.com/Destin-Vacation-Rentals.d6906.Travel-Guide-VacationRentals) - [Panama City Vacation Rentals ](https://www.expedia.com/Panama-City-Beach-Vacation-Rentals.d8021.Travel-Guide-VacationRentals) - [Hilton Head Vacation Rentals ](https://www.expedia.com/Hilton-Head-Island-Vacation-Rentals.d601684.Travel-Guide-VacationRentals) - [Gulf Shores Vacation Rentals ](https://www.expedia.com/Gulf-Shores-Vacation-Rentals.d603078.Travel-Guide-VacationRentals) - [Key West Vacation Rentals ](https://www.expedia.com/Key-West-Vacation-Rentals.d1187.Travel-Guide-VacationRentals) - [Gatlinburg Vacation Rentals ](https://www.expedia.com/Gatlinburg-Vacation-Rentals.d7474.Travel-Guide-VacationRentals) - 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