
Popular airlines from Houston William Hobby Airport (HOU) to Des Moines International Airport (DSM)
- American Airlines
American Airlines
- Southwest Airlines
Southwest Airlines
- Delta
Delta
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Cheap Flights from Houston to Des Moines (HOU-DSM)
Prices were available within the past 7 days and start at $115 for one-way flights and $229 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.






Find the cheapest month to fly from Houston (HOU) to Des Moines (DSM)
November is typically the cheapest month to fly
Graph displaying average flight prices per month
Alternative airports near Des Moines
Prices were available within the past 7 days. Prices and availability are subject to change.
Origin airport | George Bush Intercontinental |
Destination airport | Des Moines Intl. |
Airlines serving | American Airlines, Delta, Southwest Airlines |
Roundtrip price | $208 |
Distance | 803 mi |
Average flight time | 2 hours 11 mins |
Houston to Des Moines Flights
The cheapest times to fly from Houston to Des Moines
On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Houston to Des Moines are during the month of August. You can find some of the cheapest flights from Houston to Des Moines with Expedia's search tool and vast selection of airlines.
The best time to book a flight from Houston to Des Moines
Sunday is one of the best days to book for cheap flights from Houston to Des Moines: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.
How to find cheap round-trip tickets from Houston to Des Moines
Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Houston to Des Moines in 2025. You can also book with separate airlines for your outbound and return journeys, from $115 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.
Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Houston to Des Moines flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.
You could also save big by booking one of Expedia's vacation packages. Bundling together your Houston to Des Moines airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.
*Terms apply.
Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.
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Top Routes from Houston
- Houston to Chicago (HOU - ORD)
- Houston to Newark Liberty Intl. Airport (HOU - EWR)
- Houston to Chicago (HOU - MDW)
- Houston to Mexico City (HOU - MEX)
- Houston to Los Angeles (HOU - LAX)
- Houston to Miami (HOU - MIA)
- Houston to New York (HOU - LGA)
- Houston to Boston (HOU - BOS)
- Houston to Denver (HOU - DEN)
- Houston to New York (HOU - JFK)
- Houston to Seattle (HOU - SEA)
- Houston to Montego Bay (HOU - MBJ)
Top Routes to Des Moines
- Chicago to Des Moines (ORD - DSM)
- Phoenix to Des Moines (PHX - DSM)
- Newark Liberty Intl. Airport to Des Moines (EWR - DSM)
- San Diego to Des Moines (SAN - DSM)
- Los Angeles to Des Moines (LAX - DSM)
- Portland to Des Moines (PDX - DSM)
- Detroit to Des Moines (DTW - DSM)
- New York to Des Moines (LGA - DSM)
- Boston to Des Moines (BOS - DSM)
- Salt Lake City to Des Moines (SLC - DSM)
- Denver to Des Moines (DEN - DSM)
- New York to Des Moines (JFK - DSM)
Top Routes from Houston
Top Routes to Des Moines
- American Airlines Chicago to Des Moines
- American Airlines Phoenix to Des Moines
- Alaska Airlines Portland to Des Moines
- Delta Detroit to Des Moines
- Delta New York to Des Moines
- Delta Boston to Des Moines
- Delta Denver to Des Moines
- Delta New York to Des Moines
- Alaska Airlines Seattle to Des Moines
- American Airlines Dallas to Des Moines
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Houston
Nearby Airports
- Ellington Field Airport (EFD)
- George Bush Intercontinental Airport (IAH)
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