$88 Cheap Flights from New Orleans (MSY) to Des Moines (DSM)

View $88 flight on Fri, Dec 5, 2025Opens in a new window

Popular airlines from Louis Armstrong New Orleans Intl. Airport (MSY) to Des Moines International Airport (DSM)

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Cheap Flights from New Orleans to Des Moines (MSY-DSM)

Prices were available within the past 7 days and start at $88 for one-way flights and $173 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Thu, Nov 6 - Thu, Nov 13
MSY
New Orleans
DSM
Des Moines
$173 Roundtrip, found 6 days ago
$173
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Thu, Nov 6 from New Orleans to Des Moines, returning Thu, Nov 13, priced at $173 found 6 days ago
Frontier Airlines
Thu, Nov 6 - Sun, Nov 16
MSY
New Orleans
DSM
Des Moines
$212 Roundtrip, found 6 days ago
$212
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Thu, Nov 6 from New Orleans to Des Moines, returning Sun, Nov 16, priced at $212 found 6 days ago
Frontier Airlines
Sun, Nov 9 - Thu, Nov 13
MSY
New Orleans
DSM
Des Moines
$219 Roundtrip, found 5 days ago
$219
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Sun, Nov 9 from New Orleans to Des Moines, returning Thu, Nov 13, priced at $219 found 5 days ago
Frontier Airlines
Thu, Nov 6 - Thu, Nov 13
MSY
New Orleans
DSM
Des Moines
$230 Roundtrip, found 2 days ago
$230
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Thu, Nov 6 from New Orleans to Des Moines, returning Thu, Nov 13, priced at $230 found 2 days ago
Frontier Airlines
Thu, Nov 13 - Fri, Nov 21
MSY
New Orleans
DSM
Des Moines
$240 Roundtrip, found 5 days ago
$240
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Thu, Nov 13 from New Orleans to Des Moines, returning Fri, Nov 21, priced at $240 found 5 days ago
Frontier Airlines
Fri, Dec 12 - Mon, Dec 15
MSY
New Orleans
DSM
Des Moines
$245 Roundtrip, found 3 days ago
$245
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Fri, Dec 12 from New Orleans to Des Moines, returning Mon, Dec 15, priced at $245 found 3 days ago
American Airlines
Wed, Dec 24 - Wed, Dec 31
MSY
New Orleans
DSM
Des Moines
$281 Roundtrip, found 3 days ago
$281
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Dec 24 from New Orleans to Des Moines, returning Wed, Dec 31, priced at $281 found 3 days ago
Delta
Thu, Jan 1 - Sun, Jan 18
MSY
New Orleans
DSM
Des Moines
$281 Roundtrip, found 3 days ago
$281
Roundtrip
found 3 days ago
Select Delta flight, departing Thu, Jan 1 from New Orleans to Des Moines, returning Sun, Jan 18, priced at $281 found 3 days ago
United
Sat, Jan 17 - Mon, Jan 19
MSY
New Orleans
DSM
Des Moines
$299 Roundtrip, found 4 days ago
$299
Roundtrip
found 4 days ago
Select United flight, departing Sat, Jan 17 from New Orleans to Des Moines, returning Mon, Jan 19, priced at $299 found 4 days ago
Southwest Airlines
Tue, Dec 9 - Thu, Dec 18
MSY
New Orleans
DSM
Des Moines
$313 Roundtrip, found 2 days ago
$313
Roundtrip
found 2 days ago
Select Southwest Airlines flight, departing Tue, Dec 9 from New Orleans to Des Moines, returning Thu, Dec 18, priced at $313 found 2 days ago

Find the cheapest month to fly from New Orleans (MSY) to Des Moines (DSM)

August is typically the cheapest month to fly

From $197 - $646 per traveler.

Alternative airports near Des Moines

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Des Moines Intl. DSM. Cheapest and Closest option available. Average driving time to city center is 10 minutes. Flights from $465
DSM
Des Moines Intl.
CheapestClosest
Average driving time to city center10 min
Flights from $465

Frequently asked questions

How much does a flight from Louis Armstrong New Orleans Intl. Airport (MSY) to Des Moines Intl. Airport (DSM) cost?
Secure a cheap one-way flight from $88 or cheap return flight from $173 from Louis Armstrong New Orleans Intl. Airport (MSY) to Des Moines Intl. Airport (DSM) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Louis Armstrong New Orleans Intl. Airport (MSY) to Des Moines Intl. Airport (DSM)?
Traveling in November is a great way to save, as it's the cheapest month for flights between MSY and DSM. You'll typically find the lowest fares during the off-season.
What is the cheapest airline that flies from Louis Armstrong New Orleans Intl. Airport (MSY) to Des Moines Intl. Airport (DSM)?
Expedia's filter tool lets you easily compare different airlines, travel time and fares all in one place. Select your preferences, then sort by "Price (lowest to highest)" to find the carrier with the cheapest MSY to DSM flight.
How many flights per day from Louis Armstrong New Orleans Intl. Airport (MSY) to Des Moines Intl. Airport (DSM)?
You'll need to hop on a flight with a layover if you're traveling from Louis Armstrong New Orleans Intl. Airport (MSY) to Des Moines Intl. Airport (DSM). Direct flights don't operate daily on this route. However, just filter your search to include one or more stops to discover an option that works for you.
What day of the week has the most flights from MSY to DSM?
You'll generally find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Louis Armstrong New Orleans Intl. Airport (MSY) to Des Moines Intl. Airport (DSM)?
Select a flight from Louis Armstrong New Orleans Intl. Airport (MSY) to Des Moines Intl. Airport (DSM) that takes off before 3 PM to reduce the likelihood of delays. Departures after this hour have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Louis Armstrong New Orleans Intl. Airport (MSY) to Des Moines Intl. Airport (DSM) last-minute?
Last-minute fares from MSY to DSM are usually more expensive. To secure the lowest rates, start looking for flights well in advance. That said, if your travel plans are flexible, it's possible to land a cheap ticket right before your journey.
Is it cheaper to book a MSY to DSM flight and hotel package?
You'll generally save money by booking a MSY to DSM flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one convenient place. After choosing your preferred accommodations and flights, you can add extras such as activities, tours and car rentals.
Can I cancel or change the date of my flight from Louis Armstrong New Orleans Intl. Airport (MSY) to Des Moines Intl. Airport (DSM)?
Usually, it's possible to reschedule or cancel your MSY to DSM flight. However, if it's been more than 24 hours since booking, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find further details on our Customer Service portal.

Travel information

Origin airport
Louis Armstrong New Orleans Intl.
Destination airport
Des Moines Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$173
Distance
819 mi
Average flight time
7 hours 19 mins

Book with confidence

New Orleans to Des Moines Flights

The cheapest times to fly from New Orleans to Des Moines

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from New Orleans to Des Moines are during the month of November. You can find some of the cheapest flights from New Orleans to Des Moines with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from New Orleans to Des Moines

Sunday is one of the best days to book for cheap flights from New Orleans to Des Moines: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from New Orleans to Des Moines

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from New Orleans to Des Moines in 2025. You can also book with separate airlines for your outbound and return journeys, from $88 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap New Orleans to Des Moines flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your New Orleans to Des Moines airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

New Orleans to Des Moines Flights

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*Available to One Key members.