$173 Cheap American Airlines flights Charlotte (CLT) to Des Moines (DSM)

You’ll discover cheap return American Airlines flights from $250 from CLT to DSM by filtering your results from “Price (lowest to highest)” on Expedia. Or search for bargains from $173 for a one-way journey.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

January is one of the most affordable months to fly to Des Moines with American Airlines. You could also find fantastic deals on one-way and round-trip fares in December.

Begin your search one to three months before your departure to get cheaper fares on American Airlines flights from Charlotte-Douglas Intl. Airport (CLT) to Des Moines Intl. Airport (DSM). You can save 25% by booking your domestic flight 34 to 86 days in advance versus last-minute reservations made 6 to 12 days out. You could also cut costs by buying your fare on a Sunday, as it’s 6% cheaper on average than a Monday, the most expensive day to book.* Get the timing right, and you can enjoy significant savings on domestic trips.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Choose from one of American Airlines’s 14 direct weekly flights from Charlotte-Douglas Intl. Airport (CLT) to Des Moines Intl. Airport (DSM). To view available options, enter your destination, origin and dates and hit search. Then select the “Nonstop” and “Airline” filters.

On average, it takes 2h 32m to travel nonstop from Charlotte-Douglas Intl. Airport (CLT) to Des Moines Intl. Airport (DSM) with American Airlines.

American Airlines has the most flights from Charlotte-Douglas Intl. Airport (CLT) to Des Moines Intl. Airport (DSM) on Saturday. With up to 2 daily departures, you’ll get the most flexibility on this day.

The earliest American Airlines flight from CLT to DSM takes off at 12:06PM UTC-5, landing at 1:36PM UTC-6. If you want to head off later, the last American Airlines flight leaves CLT at 8:29PM UTC-5 and lands at DSM at 10:05PM UTC-6. Flying early is generally a good idea as morning and mid-morning flights tend to experience fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

Des Moines Intl. Airport (DSM) is the main Des Moines hub for American Airlines flights from Charlotte-Douglas Intl. Airport (CLT).

For the Charlotte-Douglas Intl. Airport (CLT) to Des Moines Intl. Airport (DSM) route, American Airlines typically operates Airbus A319 and Airbus A320 planes. Don’t forget that last-minute changes are possible for operational purposes, meaning your flight may be on a different aircraft.

Typically, you can cancel or reschedule your flight, although additional charges may apply if your booking was made over 24 hours ago. Prefer to keep your options open? Use Expedia’s “Changes included” and “No cancel fee” filters to find flights that won’t charge extra if you need to adjust your plans. To modify your itinerary, go to “Trips,” select your flight and click on “Manage Booking” for more information.