$80 Cheap Flights from Greenville (GSP) to Des Moines (DSM)

Popular airlines from Greenville-Spartanburg Intl. Airport (GSP) to Des Moines International Airport (DSM)

Cheap Flights from Greenville to Des Moines (GSP-DSM)

Prices were available within the past 7 days and start at $80 for one-way flights and $171 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
American Airlines
United
United
American Airlines
United
United
Southwest Airlines
United
Delta

Find the cheapest month to fly from Greenville (GSP) to Des Moines (DSM)

August is typically the cheapest month to fly

From $203 - $718 per traveler.

Graph displaying average flight prices per month

Alternative airports near Des Moines

Prices were available within the past 7 days. Prices and availability are subject to change.

Flights from Greenville (GSP) to Des Moines (DSM)
Origin airport
Greenville-Spartanburg Intl.
Destination airport
Des Moines Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$170
Distance
770 mi

Greenville to Des Moines Flights

The cheapest times to fly from Greenville to Des Moines

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Greenville to Des Moines are during the month of October. You can find some of the cheapest flights from Greenville to Des Moines with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Greenville to Des Moines

Sunday is one of the best days to book for cheap flights from Greenville to Des Moines: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Greenville to Des Moines

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Greenville to Des Moines in 2025. You can also book with separate airlines for your outbound and return journeys, from $80 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Greenville to Des Moines flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Greenville to Des Moines airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Greenville-Spartanburg Intl. Airport (GSP) to Des Moines Intl. Airport (DSM) cost?
Discover the latest flight deals from GSP to DSM by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from GSP to DSM?
The cheapest flights from GSP to DSM are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from GSP to DSM?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from GSP to DSM. Sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Greenville-Spartanburg Intl. Airport (GSP) to Des Moines Intl. Airport (DSM)?
You'll need to hop on a flight with a layover when traveling from Greenville-Spartanburg Intl. Airport (GSP) to Des Moines Intl. Airport (DSM). There are no daily direct flights on this route. However, just filter your search to include one or two stops to find an option that works for you.
What day of the week has the most flights from GSP to DSM?
Friday is typically the busiest day for flights, while Tuesday is often the quietest.* Keep in mind that flight schedules can vary based on a range of factors, such as the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Greenville-Spartanburg Intl. Airport (GSP) to Des Moines Intl. Airport (DSM)?
To arrive at Des Moines Intl. Airport (DSM) without delays, book a flight that leaves Greenville-Spartanburg Intl. Airport (GSP) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Greenville-Spartanburg Intl. Airport (GSP) to Des Moines Intl. Airport (DSM) last-minute?
Last-minute fares from GSP to DSM are usually more expensive. To secure the best prices, start searching for flights as soon as possible. That being said, if you're flexible with your travel dates, you may score a cheap ticket right before your journey.
Is it cheaper to book a GSP to DSM flight and hotel package?
Booking a GSP to DSM flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels in one place. Select from our impressive range of stays and then add car rentals, flights and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Greenville-Spartanburg Intl. Airport (GSP) to Des Moines Intl. Airport (DSM)?
Generally, it's possible to reschedule or cancel your GSP to DSM flight. However, if the booking was made more than 24 hours ago, additional fees may apply. Check your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find more information on our Customer Service portal.

Explore a world of travel with Expedia

*Available to One Key members.