$229 Cheap Flights from Lexington (LEX) to Des Moines (DSM)

View $229 flight on Tue, Apr 7, 2026Opens in a new window

Popular airlines from Blue Grass Airport (LEX) to Des Moines International Airport (DSM)

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Cheap Flights from Lexington to Des Moines (LEX-DSM)

Prices were available within the past 7 days and start at $229 for one-way flights and $249 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Thu, Dec 11 - Fri, Jan 2
LEX
Lexington
DSM
Des Moines
$249 Roundtrip, found 6 hours ago
$249
Roundtrip
found 6 hours ago
Select Delta flight, departing Thu, Dec 11 from Lexington to Des Moines, returning Fri, Jan 2, priced at $249 found 6 hours ago
United
Sat, Nov 15 - Tue, Nov 18
LEX
Lexington
DSM
Des Moines
$249 Roundtrip, found 13 hours ago
$249
Roundtrip
found 13 hours ago
Select United flight, departing Sat, Nov 15 from Lexington to Des Moines, returning Tue, Nov 18, priced at $249 found 13 hours ago
Delta
Wed, Nov 12 - Mon, Nov 17
LEX
Lexington
DSM
Des Moines
$254 Roundtrip, found 13 hours ago
$254
Roundtrip
found 13 hours ago
Select Delta flight, departing Wed, Nov 12 from Lexington to Des Moines, returning Mon, Nov 17, priced at $254 found 13 hours ago
Delta
Tue, Nov 4 - Sun, Nov 9
LEX
Lexington
DSM
Des Moines
$259 Roundtrip, found 2 days ago
$259
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Nov 4 from Lexington to Des Moines, returning Sun, Nov 9, priced at $259 found 2 days ago
United
Tue, Apr 7 - Sat, Apr 11
LEX
Lexington
DSM
Des Moines
$269 Roundtrip, found 15 hours ago
$269
Roundtrip
found 15 hours ago
Select United flight, departing Tue, Apr 7 from Lexington to Des Moines, returning Sat, Apr 11, priced at $269 found 15 hours ago
Delta
Mon, Nov 3 - Tue, Nov 11
LEX
Lexington
DSM
Des Moines
$279 Roundtrip, found 2 days ago
$279
Roundtrip
found 2 days ago
Select Delta flight, departing Mon, Nov 3 from Lexington to Des Moines, returning Tue, Nov 11, priced at $279 found 2 days ago
Delta
Sat, Dec 13 - Fri, Jan 2
LEX
Lexington
DSM
Des Moines
$284 Roundtrip, found 6 hours ago
$284
Roundtrip
found 6 hours ago
Select Delta flight, departing Sat, Dec 13 from Lexington to Des Moines, returning Fri, Jan 2, priced at $284 found 6 hours ago
Delta
Wed, Nov 12 - Sun, Nov 16
LEX
Lexington
DSM
Des Moines
$289 Roundtrip, found 13 hours ago
$289
Roundtrip
found 13 hours ago
Select Delta flight, departing Wed, Nov 12 from Lexington to Des Moines, returning Sun, Nov 16, priced at $289 found 13 hours ago
American Airlines
Sat, Jan 10 - Sun, Jan 11
LEX
Lexington
DSM
Des Moines
$293 Roundtrip, found 7 hours ago
$293
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Sat, Jan 10 from Lexington to Des Moines, returning Sun, Jan 11, priced at $293 found 7 hours ago
American Airlines
Fri, Feb 6 - Sun, Feb 8
LEX
Lexington
DSM
Des Moines
$294 Roundtrip, found 4 days ago
$294
Roundtrip
found 4 days ago
Select American Airlines flight, departing Fri, Feb 6 from Lexington to Des Moines, returning Sun, Feb 8, priced at $294 found 4 days ago

Find the cheapest month to fly from Lexington (LEX) to Des Moines (DSM)

May is typically the cheapest month to fly

From $223 - $602 per traveler.

Alternative airports near Des Moines

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Des Moines Intl. DSM. Cheapest and Closest option available. Average driving time to city center is 10 minutes. Flights from $254
DSM
Des Moines Intl.
CheapestClosest
Average driving time to city center10 min
Flights from $254

Frequently asked questions

How much does a flight from Blue Grass Airport (LEX) to Des Moines Intl. Airport (DSM) cost?
Lock in a cheap one-way flight from $229 or cheap return flight from $249 from Blue Grass Airport (LEX) to Des Moines Intl. Airport (DSM) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Blue Grass Airport (LEX) to Des Moines Intl. Airport (DSM)?
December is the cheapest month to fly from LEX to DSM. Traveling during quieter months is often the key to finding better deals on flights.
What is the cheapest airline that flies from Blue Grass Airport (LEX) to Des Moines Intl. Airport (DSM)?
To find the cheapest airline flying from LEX to DSM, use Expedia's filter tool. Tailor your search based on what matters most to you, such as preferred carriers and number of stops. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from Blue Grass Airport (LEX) to Des Moines Intl. Airport (DSM)?
You'll need to catch a flight with a layover when traveling from Blue Grass Airport (LEX) to Des Moines Intl. Airport (DSM). Direct flights don't operate daily on this route. However, just filter your search to include one or two stops to find an option that works for you.
What day of the week has the most flights from LEX to DSM?
Typically you'll find the largest variety of flight choices on a Friday. Tuesdays tend to be the quietest.* However, this can vary depending on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Blue Grass Airport (LEX) to Des Moines Intl. Airport (DSM)?
To avoid possible delays on the Blue Grass Airport (LEX) to Des Moines Intl. Airport (DSM) route, aim to fly before 3 PM. Later departures are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Blue Grass Airport (LEX) to Des Moines Intl. Airport (DSM) last-minute?
Booking your ticket from LEX to DSM right before your trip is typically more expensive. But if you're flexible with your travel dates and times, you could land a cheap last-minute fare.
Is it cheaper to book a LEX to DSM flight and hotel package?
Securing a LEX to DSM flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip all in one place. Pick from our wide range of accommodations and then add activities, flights and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Blue Grass Airport (LEX) to Des Moines Intl. Airport (DSM)?
If you reserved your LEX to DSM flight in the last 24 hours, you may be able to modify or cancel it at no cost. Depending on the airline and the fare type you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal if you want more information.

Travel information

Origin airport
Blue Grass
Destination airport
Des Moines Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$248
Distance
537 mi

Book with confidence

Lexington to Des Moines Flights

The cheapest times to fly from Lexington to Des Moines

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Lexington to Des Moines are during the month of December. You can find some of the cheapest flights from Lexington to Des Moines with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Lexington to Des Moines

Sunday is one of the best days to book for cheap flights from Lexington to Des Moines: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Lexington to Des Moines

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Lexington to Des Moines in 2025. You can also book with separate airlines for your outbound and return journeys, from $229 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Lexington to Des Moines flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Lexington to Des Moines airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Lexington to Des Moines Flights

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*Available to One Key members.