$561 Cheap Flights from Madrid (MAD) to Des Moines (DSM)

View $561 flight on Mon, Feb 2, 2026Opens in a new window

Popular airlines from Adolfo Suarez Madrid-Barajas Airport (MAD) to Des Moines International Airport (DSM)

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Cheap Flights from Madrid to Des Moines (MAD-DSM)

Prices were available within the past 7 days and start at $561 for one-way flights and $832 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Wed, Jan 14 - Tue, Jan 27
MAD
Madrid
DSM
Des Moines
$832 Roundtrip, found 20 hours ago
$832
Roundtrip
found 20 hours ago
Select Delta flight, departing Wed, Jan 14 from Madrid to Des Moines, returning Tue, Jan 27, priced at $832 found 20 hours ago
Delta
Wed, Jan 14 - Thu, Jan 29
MAD
Madrid
DSM
Des Moines
$841 Roundtrip, found 20 hours ago
$841
Roundtrip
found 20 hours ago
Select Delta flight, departing Wed, Jan 14 from Madrid to Des Moines, returning Thu, Jan 29, priced at $841 found 20 hours ago
Virgin Atlantic
Mon, Jan 12 - Tue, Jan 27
MAD
Madrid
DSM
Des Moines
$841 Roundtrip, found 20 hours ago
$841
Roundtrip
found 20 hours ago
Select Virgin Atlantic flight, departing Mon, Jan 12 from Madrid to Des Moines, returning Tue, Jan 27, priced at $841 found 20 hours ago
Air Canada
Wed, Dec 24 - Wed, Jan 21
MAD
Madrid
DSM
Des Moines
$843 Roundtrip, found 2 days ago
$843
Roundtrip
found 2 days ago
Select Air Canada flight, departing Wed, Dec 24 from Madrid to Des Moines, returning Wed, Jan 21, priced at $843 found 2 days ago
Virgin Atlantic
Mon, Jan 12 - Thu, Jan 29
MAD
Madrid
DSM
Des Moines
$845 Roundtrip, found 20 hours ago
$845
Roundtrip
found 20 hours ago
Select Virgin Atlantic flight, departing Mon, Jan 12 from Madrid to Des Moines, returning Thu, Jan 29, priced at $845 found 20 hours ago
Delta
Wed, Jan 14 - Sun, Feb 1
MAD
Madrid
DSM
Des Moines
$849 Roundtrip, found 20 hours ago
$849
Roundtrip
found 20 hours ago
Select Delta flight, departing Wed, Jan 14 from Madrid to Des Moines, returning Sun, Feb 1, priced at $849 found 20 hours ago
Delta
Tue, Jan 13 - Sun, Feb 1
MAD
Madrid
DSM
Des Moines
$850 Roundtrip, found 20 hours ago
$850
Roundtrip
found 20 hours ago
Select Delta flight, departing Tue, Jan 13 from Madrid to Des Moines, returning Sun, Feb 1, priced at $850 found 20 hours ago
Air Canada
Wed, Dec 24 - Wed, Jan 21
MAD
Madrid
DSM
Des Moines
$852 Roundtrip, found 2 days ago
$852
Roundtrip
found 2 days ago
Select Air Canada flight, departing Wed, Dec 24 from Madrid to Des Moines, returning Wed, Jan 21, priced at $852 found 2 days ago
United
Wed, Jan 28 - Thu, Feb 12
MAD
Madrid
DSM
Des Moines
$853 Roundtrip, found 20 hours ago
$853
Roundtrip
found 20 hours ago
Select United flight, departing Wed, Jan 28 from Madrid to Des Moines, returning Thu, Feb 12, priced at $853 found 20 hours ago
Lufthansa
Sat, Jan 17 - Tue, Feb 17
MAD
Madrid
DSM
Des Moines
$855 Roundtrip, found 3 days ago
$855
Roundtrip
found 3 days ago
Select Lufthansa flight, departing Sat, Jan 17 from Madrid to Des Moines, returning Tue, Feb 17, priced at $855 found 3 days ago

Alternative airports near Des Moines

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Des Moines Intl. DSM. Cheapest and Closest option available. Average driving time to city center is 10 minutes. Flights from $896
DSM
Des Moines Intl.
CheapestClosest
Average driving time to city center10 min
Flights from $896

Frequently asked questions

How much does a flight from Adolfo Suarez Madrid-Barajas Airport (MAD) to Des Moines Intl. Airport (DSM) cost?
Snag a cheap one-way flight from $561 or cheap return flight from $832 from Adolfo Suarez Madrid-Barajas Airport (MAD) to Des Moines Intl. Airport (DSM) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Adolfo Suarez Madrid-Barajas Airport (MAD) to Des Moines Intl. Airport (DSM)?
January is the most affordable month to fly from MAD to DSM. Traveling during quieter months is often the key to scoring lower fares.
What is the cheapest airline that flies from Adolfo Suarez Madrid-Barajas Airport (MAD) to Des Moines Intl. Airport (DSM)?
To find the cheapest airline that'll fly you from MAD to DSM, use Expedia's filter tool. Customize your search based on your travel style, such as preferred carriers and number of stops. You can then sort your results by "Price (lowest to highest)" to discover the cheapest flight right away.
How many flights per day from Adolfo Suarez Madrid-Barajas Airport (MAD) to Des Moines Intl. Airport (DSM)?
There are no daily nonstop flights departing from Adolfo Suarez Madrid-Barajas Airport (MAD) to Des Moines Intl. Airport (DSM). But you can book flights with layovers. Filter your search on Expedia to include one or two stops, and you'll be cruising above the clouds before you know it.
What day of the week has the most flights from MAD to DSM?
Friday is usually the busiest day for flights, while Tuesday tends to be the quietest.* Keep in mind that flight schedules can change depending on a number of factors, such as the airline and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Adolfo Suarez Madrid-Barajas Airport (MAD) to Des Moines Intl. Airport (DSM)?
To avoid potential delays on the Adolfo Suarez Madrid-Barajas Airport (MAD) to Des Moines Intl. Airport (DSM) route, aim to fly before 3 PM. Later departures are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Adolfo Suarez Madrid-Barajas Airport (MAD) to Des Moines Intl. Airport (DSM) last-minute?
Holding off until just before your trip to book your flight from MAD to DSM generally means paying more. Although you may find some last-minute offers, they're not always guaranteed. Be flexible with your travel plans for a better chance of snagging a bargain.
Is it cheaper to book a MAD to DSM flight and hotel package?
Compared with arranging hotels and flights separately, booking a MAD to DSM flight and hotel package with Expedia could result in significant savings. Better yet, having everything in one place will take the hassle out of planning your trip. Just pick your flights and select from our wide range of hotels, then tailor your trip with extras like car rentals and activities.
Can I cancel or change the date of my flight from Adolfo Suarez Madrid-Barajas Airport (MAD) to Des Moines Intl. Airport (DSM)?
Typically, it's possible to reschedule or cancel your MAD to DSM flight. However, if it's been more than 24 hours since booking, additional fees may apply. Refer to your airline's policies in your itinerary to see what changes are possible and if any costs are involved. You'll also find more information on our Customer Service portal.

Travel information

Origin airport
Adolfo Suárez Madrid-Barajas
Destination airport
Des Moines Intl.
Airlines serving
Aer Lingus, Air France, American Airlines, British Airways, Delta, Iberia, KLM, Lufthansa, United, Virgin Atlantic
Roundtrip price
$832
Distance
4460 mi

Book with confidence

Madrid to Des Moines Flights

The cheapest times to fly from Madrid to Des Moines

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Madrid to Des Moines are during the month of January. You can find some of the cheapest flights from Madrid to Des Moines with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Madrid to Des Moines

Sunday is one of the best days to book for cheap flights from Madrid to Des Moines: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Madrid to Des Moines

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Madrid to Des Moines in 2025. You can also book with separate airlines for your outbound and return journeys, from $561 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Madrid to Des Moines flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Madrid to Des Moines airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Madrid to Des Moines Flights

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*Available to One Key members.