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$135 Cheap Flights from Milwaukee (MKE) to Des Moines (DSM)

View $135 flight on Mon, Feb 22, 2027Opens in a new window

Popular airlines from General Mitchell Intl. Airport (MKE) to Des Moines International Airport (DSM)

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Cheap Flights from Milwaukee to Des Moines (MKE-DSM)

Prices were available within the past 7 days and start at $135 for one-way flights and $284 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Fri, Oct 9 - Mon, Oct 12
MKE
Milwaukee
DSM
Des Moines
$284 Roundtrip, found 1 day ago
$284
Roundtrip
found 1 day ago
Select United flight, departing Fri, Oct 9 from Milwaukee to Des Moines, returning Mon, Oct 12, priced at $284 found 1 day ago
United
Fri, Oct 9 - Mon, Oct 12
MKE
Milwaukee
DSM
Des Moines
$287 Roundtrip, found 1 day ago
$287
Roundtrip
found 1 day ago
Select United flight, departing Fri, Oct 9 from Milwaukee to Des Moines, returning Mon, Oct 12, priced at $287 found 1 day ago
American Airlines
Thu, Nov 12 - Sat, Nov 14
MKE
Milwaukee
DSM
Des Moines
$297 Roundtrip, found 3 hours ago
$297
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Thu, Nov 12 from Milwaukee to Des Moines, returning Sat, Nov 14, priced at $297 found 3 hours ago
Southwest Airlines
Thu, Oct 29 - Mon, Nov 2
MKE
Milwaukee
DSM
Des Moines
$297 Roundtrip, found 1 hour ago
$297
Roundtrip
found 1 hour ago
Select Southwest Airlines flight, departing Thu, Oct 29 from Milwaukee to Des Moines, returning Mon, Nov 2, priced at $297 found 1 hour ago
Southwest Airlines
Fri, Oct 30 - Sun, Nov 1
MKE
Milwaukee
DSM
Des Moines
$302 Roundtrip, found 1 day ago
$302
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Fri, Oct 30 from Milwaukee to Des Moines, returning Sun, Nov 1, priced at $302 found 1 day ago
Southwest Airlines
Thu, Oct 29 - Mon, Nov 2
MKE
Milwaukee
DSM
Des Moines
$307 Roundtrip, found 1 hour ago
$307
Roundtrip
found 1 hour ago
Select Southwest Airlines flight, departing Thu, Oct 29 from Milwaukee to Des Moines, returning Mon, Nov 2, priced at $307 found 1 hour ago
United
Fri, Oct 30 - Mon, Nov 2
MKE
Milwaukee
DSM
Des Moines
$309 Roundtrip, found 4 hours ago
$309
Roundtrip
found 4 hours ago
Select United flight, departing Fri, Oct 30 from Milwaukee to Des Moines, returning Mon, Nov 2, priced at $309 found 4 hours ago
Southwest Airlines
Mon, Dec 21 - Tue, Dec 29
MKE
Milwaukee
DSM
Des Moines
$312 Roundtrip, found 3 days ago
$312
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Mon, Dec 21 from Milwaukee to Des Moines, returning Tue, Dec 29, priced at $312 found 3 days ago
Southwest Airlines
Wed, Oct 28 - Sun, Nov 1
MKE
Milwaukee
DSM
Des Moines
$312 Roundtrip, found 4 hours ago
$312
Roundtrip
found 4 hours ago
Select Southwest Airlines flight, departing Wed, Oct 28 from Milwaukee to Des Moines, returning Sun, Nov 1, priced at $312 found 4 hours ago
Delta
Thu, Nov 12 - Sat, Nov 14
MKE
Milwaukee
DSM
Des Moines
$337 Roundtrip, found 3 hours ago
$337
Roundtrip
found 3 hours ago
Select Delta flight, departing Thu, Nov 12 from Milwaukee to Des Moines, returning Sat, Nov 14, priced at $337 found 3 hours ago

Find the cheapest month to fly from Milwaukee (MKE) to Des Moines (DSM)

April is typically the cheapest month to fly

From $199 - $317 per traveler.

What you need to know for your flight from General Mitchell Intl. to Des Moines Intl.

Milwaukee (MKE) to Des Moines (DSM) at a glance

Travel between Milwaukee (MKE) and Des Moines (DSM) with a range of airlines on this short domestic route. Discover cheap flights from Milwaukee and compare options from both full-service and budget carriers to find an itinerary that aligns with your budget and travel schedule. Whether you're eager to explore the attractions and neighborhoods of Des Moines or simply passing through, you can easily find key details for flights from General Mitchell International Airport to Des Moines International Airport.

  • Fastest flight duration: around 2h 30m in-flight, plus roughly 1 hour layover with one stop
  • Route distance: roughly 300 miles (485 km)
  • Flights per week: around 8 departures on average
  • Typical fares (one-way): economy tickets often range from $115–$495, depending on seasonality and how far ahead you book

Flights from General Mitchell International Airport (MKE) to Des Moines International Airport (DSM)

Here are the top airlines favored by travelers flying from Milwaukee to Des Moines, typically opting for one-stop routes. Popular layover options include O'Hare International Airport (ORD) with a layover of about 1 hour and 15 minutes, Minneapolis - St. Paul International Airport (MSP) with approximately 1 hour and 30 minutes, and Detroit Metropolitan Wayne County Airport (DTW) with a brief 35-minute layover. These choices allow you to customize your travel plans by balancing price, total travel time, and cabin class to secure the best itinerary.

  • Delta: This comprehensive carrier provides one-stop flights, with one-way ticket prices usually falling between $115 and $350. Delta represents about 34% of departures on this route, featuring an in-flight duration of 2 hours and 30 minutes, and a total travel time of approximately 3 hours and 45 minutes, including layover time.
  • United: Another full-service airline, United offers one-stop travel options, with one-way fares typically ranging from $125 to $320. United accounts for around 33% of flights on this route, with a flying time of 2 hours and 30 minutes and a total journey duration of about 3 hours and 45 minutes, factoring in layovers.
  • American Airlines: This full-service airline provides one-stop services with one-way fares generally between $120 and $600. American Airlines makes up roughly 29% of departures on this route, with a flight time of 2 hours and 30 minutes and an overall travel time of around 3 hours and 45 minutes, including any layovers.
  • Southwest Airlines: As a budget-friendly option, Southwest Airlines offers one-stop service, with one-way fares typically ranging from $115 to $195. This airline contributes to about 5% of departures on this route, maintaining an in-flight duration of 2 hours and 30 minutes and a total journey time of roughly 3 hours and 45 minutes, including layovers.

Alternative route from Milwaukee (MKE) to Des Moines (DSM)

  • Waukesha to Des Moines (UES-DSM): Waukesha County Airport (UES) is located approximately 18 miles from General Mitchell International Airport (MKE).

How to find the best prices for flights from Milwaukee (MKE) to Des Moines (DSM)

Getting some of the best deals on flights from Milwaukee to Des Moines is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are usually found when booking 2-8 weeks in advance, which coincides with when most travelers make their reservations. Morning departures between 5 a.m. and 12 p.m. tend to be both cheaper and the most popular. Additionally, flying on Tuesday generally offers lower prices, although Sunday remains the most popular travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.*
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Des Moines International Airport from General Mitchell International Airport

Des Moines welcomes travelers from Milwaukee with a range of transport options based on price, convenience, and proximity. Here's how to reach Des Moines efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Des Moines, with private rides that can be arranged in advance.
  • Car rental: Renting a car from Des Moines International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Des Moines International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.

Frequently asked questions

How much does a flight from Milwaukee, WI (MKE-General Mitchell Intl.) to Des Moines, IA (DSM-Des Moines Intl.) cost?
You can find cheap one-way flights from $135 and cheap return flights from $284 Milwaukee, WI (MKE-General Mitchell Intl.) to Des Moines, IA (DSM-Des Moines Intl.) with Expedia. One-way flights typically cost between $118 and $594, and return flights often range between $314 and $818. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Milwaukee, WI (MKE-General Mitchell Intl.) to Des Moines, IA (DSM-Des Moines Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Milwaukee, WI (MKE-General Mitchell Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
January is the cheapest month to fly from Milwaukee, WI (MKE) to Des Moines, IA (DSM), with average round-trip fares around $281. This price is about 34% lower than the average throughout the year, as winter travel tends to see less demand. Other affordable months to consider are September and November.*Averages based on flights available on Expedia in the last year.
Which airlines fly direct from Milwaukee, WI (MKE-General Mitchell Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
Enter MKE to DSM and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Milwaukee, WI (MKE-General Mitchell Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
Southwest Airlines is one of the cheapest airlines offering connecting flights from Milwaukee (MKE) to Des Moines (DSM), with round-trip tickets starting from around $475 with a layover in Denver (DEN). Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Milwaukee, WI (MKE-General Mitchell Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
To find a cheap flight from Milwaukee, WI (MKE-General Mitchell Intl.) to Des Moines, IA (DSM-Des Moines Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Milwaukee, WI (MKE-General Mitchell Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
When flying from Milwaukee, WI (MKE) to Des Moines, IA (DSM), January and November are your best bets. Average return flight prices hover around $248, making these months both economical and convenient. January is often less busy, while November can offer a lovely autumn backdrop for your travels.*Prices based on flights available on Expedia in the last year.
What is the earliest flight from Milwaukee, WI (MKE-General Mitchell Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
The earliest flight from General Mitchell International Airport (MKE) in Milwaukee to Des Moines International Airport (DSM) usually departs at 5:00 AM, operated by American Airlines. This seasonal service is active in December, giving you a great start to your day in Des Moines. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Milwaukee, WI (MKE-General Mitchell Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
The most popular departure times for flights from General Mitchell Intl. (MKE) to Des Moines Intl. (DSM) are in the early morning, from 6am to 9am. About 33% of passengers choose this time window. Many major carriers, including United Airlines, American Airlines and Delta, offer flights during this window. This timing is favored as it helps you make the most of your day in Des Moines.
How long does it take to fly from Milwaukee, WI (MKE-General Mitchell Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
Flying from MKE to DSM with a connection usually takes about 6 hours 20 minutes, traveling roughly 310 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Milwaukee, WI (MKE-General Mitchell Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
First class seats are offered on the MKE to DSM route. First class cabins are available on:

  • American Airlines
  • Delta Air Lines
  • United Airlines

How do I earn miles on a Milwaukee, WI (MKE-General Mitchell Intl.) to Des Moines, IA (DSM-Des Moines Intl.) flight with Expedia?
It's easy to earn miles on a Milwaukee, WI (MKE-General Mitchell Intl.) to Des Moines, IA (DSM-Des Moines Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Des Moines from General Mitchell Intl. (MKE)?
If you're planning to travel to Des Moines from General Mitchell Intl. (MKE), you can fly into Des Moines Intl. (DSM) Some flights may connect through major hubs like O'Hare Intl. (ORD), Denver Intl. (DEN), Tampa Intl. (TPA) before reaching Des Moines. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Milwaukee, WI (MKE-General Mitchell Intl.) to Des Moines, IA (DSM-Des Moines Intl.) at the last minute?
Typically, booking a last minute flight from Milwaukee, WI (MKE-General Mitchell Intl.) to Des Moines, IA (DSM-Des Moines Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Milwaukee, WI (MKE-General Mitchell Intl.) to Des Moines, IA (DSM-Des Moines Intl.) flight and hotel package?
Securing a Milwaukee, WI (MKE-General Mitchell Intl.) to Des Moines, IA (DSM-Des Moines Intl.) Des Moines Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Milwaukee, WI (MKE-General Mitchell Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
If you booked your Milwaukee, WI (MKE-General Mitchell Intl.) to Des Moines, IA (DSM-Des Moines Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
General Mitchell Intl.
Destination airport
Des Moines Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$283
Distance
309 mi

Book with confidence

Milwaukee to Des Moines Flights

The cheapest times to fly from Milwaukee to Des Moines

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Milwaukee to Des Moines are during the month of October. You can find some of the cheapest flights from Milwaukee to Des Moines with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Milwaukee to Des Moines

Sunday is one of the best days to book for cheap flights from Milwaukee to Des Moines: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Milwaukee to Des Moines

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Milwaukee to Des Moines in 2026. You can also book with separate airlines for your outbound and return journeys, from $135 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Milwaukee to Des Moines flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Milwaukee to Des Moines airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Milwaukee to Des Moines Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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