$125 Cheap Flights from Pittsburgh (PIT) to Des Moines (DSM)

View $125 flight on Thu, Nov 27, 2025Opens in a new window

Popular airlines from Pittsburgh Intl. Airport (PIT) to Des Moines International Airport (DSM)

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Cheap Flights from Pittsburgh to Des Moines (PIT-DSM)

Prices were available within the past 7 days and start at $125 for one-way flights and $265 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Southwest Airlines
Wed, Dec 10 - Wed, Jan 7
PIT
Pittsburgh
DSM
Des Moines
$265 Roundtrip, found 7 hours ago
$265
Roundtrip
found 7 hours ago
Select Southwest Airlines flight, departing Wed, Dec 10 from Pittsburgh to Des Moines, returning Wed, Jan 7, priced at $265 found 7 hours ago
Southwest Airlines
Wed, Dec 10 - Wed, Jan 7
PIT
Pittsburgh
DSM
Des Moines
$270 Roundtrip, found 7 hours ago
$270
Roundtrip
found 7 hours ago
Select Southwest Airlines flight, departing Wed, Dec 10 from Pittsburgh to Des Moines, returning Wed, Jan 7, priced at $270 found 7 hours ago
United
Wed, Dec 10 - Wed, Jan 7
PIT
Pittsburgh
DSM
Des Moines
$276 Roundtrip, found 7 hours ago
$276
Roundtrip
found 7 hours ago
Select United flight, departing Wed, Dec 10 from Pittsburgh to Des Moines, returning Wed, Jan 7, priced at $276 found 7 hours ago
United
Wed, Nov 19 - Mon, Nov 24
PIT
Pittsburgh
DSM
Des Moines
$282 Roundtrip, found 4 days ago
$282
Roundtrip
found 4 days ago
Select United flight, departing Wed, Nov 19 from Pittsburgh to Des Moines, returning Mon, Nov 24, priced at $282 found 4 days ago
Southwest Airlines
Wed, Dec 10 - Wed, Jan 7
PIT
Pittsburgh
DSM
Des Moines
$285 Roundtrip, found 7 hours ago
$285
Roundtrip
found 7 hours ago
Select Southwest Airlines flight, departing Wed, Dec 10 from Pittsburgh to Des Moines, returning Wed, Jan 7, priced at $285 found 7 hours ago
Southwest Airlines
Wed, Dec 10 - Wed, Jan 7
PIT
Pittsburgh
DSM
Des Moines
$291 Roundtrip, found 7 hours ago
$291
Roundtrip
found 7 hours ago
Select Southwest Airlines flight, departing Wed, Dec 10 from Pittsburgh to Des Moines, returning Wed, Jan 7, priced at $291 found 7 hours ago
United
Wed, Nov 19 - Mon, Nov 24
PIT
Pittsburgh
DSM
Des Moines
$294 Roundtrip, found 4 days ago
$294
Roundtrip
found 4 days ago
Select United flight, departing Wed, Nov 19 from Pittsburgh to Des Moines, returning Mon, Nov 24, priced at $294 found 4 days ago
American Airlines
Thu, Dec 4 - Wed, Dec 10
PIT
Pittsburgh
DSM
Des Moines
$297 Roundtrip, found 1 day ago
$297
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Dec 4 from Pittsburgh to Des Moines, returning Wed, Dec 10, priced at $297 found 1 day ago
Delta
Wed, Dec 10 - Thu, Jan 8
PIT
Pittsburgh
DSM
Des Moines
$327 Roundtrip, found 1 hour ago
$327
Roundtrip
found 1 hour ago
Select Delta flight, departing Wed, Dec 10 from Pittsburgh to Des Moines, returning Thu, Jan 8, priced at $327 found 1 hour ago
Frontier Airlines
Fri, Dec 19 - Sun, Jan 4
PIT
Pittsburgh
DSM
Des Moines
$350 Roundtrip, found 2 days ago
$350
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Fri, Dec 19 from Pittsburgh to Des Moines, returning Sun, Jan 4, priced at $350 found 2 days ago

Find the cheapest month to fly from Pittsburgh (PIT) to Des Moines (DSM)

August is typically the cheapest month to fly

From $168 - $522 per traveler.

Alternative airports near Des Moines

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Des Moines Intl. DSM. Cheapest and Closest option available. Average driving time to city center is 10 minutes. Flights from $372
DSM
Des Moines Intl.
CheapestClosest
Average driving time to city center10 min
Flights from $372

Frequently asked questions

How much does a flight from Pittsburgh Intl. Airport (PIT) to Des Moines Intl. Airport (DSM) cost?
Snag a cheap one-way flight from $125 or cheap return flight from $265 from Pittsburgh Intl. Airport (PIT) to Des Moines Intl. Airport (DSM) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Pittsburgh Intl. Airport (PIT) to Des Moines Intl. Airport (DSM)?
The cheapest month to fly from PIT to DSM is December, when there's less demand. Off-peak season is often when better flight deals are available between these airports.
What is the cheapest airline that flies from Pittsburgh Intl. Airport (PIT) to Des Moines Intl. Airport (DSM)?
Expedia's filter tool lets you easily compare airlines, flight times and fares all in one place. Choose your preferences, then sort by "Price (lowest to highest)" to find out which carrier offers the cheapest PIT to DSM flight.
How many flights per day from Pittsburgh Intl. Airport (PIT) to Des Moines Intl. Airport (DSM)?
You'll have to book a flight with a layover if you're traveling from Pittsburgh Intl. Airport (PIT) to Des Moines Intl. Airport (DSM). Direct flights don't operate daily on this route. However, just filter your search to include one or more stops to find the best option for your trip.
What day of the week has the most flights from PIT to DSM?
Generally you'll have the most choice when it comes to flights on a Friday. Tuesdays tend to be the quietest.* However, this can vary depending on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Pittsburgh Intl. Airport (PIT) to Des Moines Intl. Airport (DSM)?
Book a flight from Pittsburgh Intl. Airport (PIT) to Des Moines Intl. Airport (DSM) that leaves before 3 PM to reduce the risk of cancellations. Departures later than this are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Pittsburgh Intl. Airport (PIT) to Des Moines Intl. Airport (DSM) last-minute?
Booking your ticket from PIT to DSM just before your journey is typically more expensive. But if you're flexible with your itinerary, you could score a cheap last-minute fare.
Is it cheaper to book a PIT to DSM flight and hotel package?
Compared with arranging hotels and flights separately, booking a PIT to DSM flight and hotel package with Expedia could result in significant savings. What's more, having everything in one convenient place will take the stress out of travel planning. Just pick your flights and choose from our extensive range of stays, then personalize your trip with extras like tours and car rentals.
Can I cancel or change the date of my flight from Pittsburgh Intl. Airport (PIT) to Des Moines Intl. Airport (DSM)?
In most cases, you can modify or cancel your PIT to DSM flight. However, additional charges may apply, especially if your booking was made over 24 hours ago. Double-check your itinerary for the airline's rules and fees on flight changes, or if you need further details, go to our Customer Service portal.

Travel information

Origin airport
Pittsburgh Intl.
Destination airport
Des Moines Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$265
Distance
701 mi

Book with confidence

Pittsburgh to Des Moines Flights

The cheapest times to fly from Pittsburgh to Des Moines

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Pittsburgh to Des Moines are during the month of December. You can find some of the cheapest flights from Pittsburgh to Des Moines with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Pittsburgh to Des Moines

Sunday is one of the best days to book for cheap flights from Pittsburgh to Des Moines: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Pittsburgh to Des Moines

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Pittsburgh to Des Moines in 2025. You can also book with separate airlines for your outbound and return journeys, from $125 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Pittsburgh to Des Moines flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Pittsburgh to Des Moines airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Pittsburgh to Des Moines Flights

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*Available to One Key members.