$129 Cheap Flights from Portland (PWM) to Des Moines (DSM)

View $129 flight on Wed, Oct 22, 2025Opens in a new window

Popular airlines from Portland Intl. Jetport Airport (PWM) to Des Moines International Airport (DSM)

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Cheap Flights from Portland to Des Moines (PWM-DSM)

Prices were available within the past 7 days and start at $129 for one-way flights and $237 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Oct 8 - Sat, Oct 11
PWM
Portland
DSM
Des Moines
$237 Roundtrip, found 5 days ago
$237
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Oct 8 from Portland to Des Moines, returning Sat, Oct 11, priced at $237 found 5 days ago
Delta
Wed, Oct 8 - Sat, Oct 11
PWM
Portland
DSM
Des Moines
$251 Roundtrip, found 5 days ago
$251
Roundtrip
found 5 days ago
Select Delta flight, departing Wed, Oct 8 from Portland to Des Moines, returning Sat, Oct 11, priced at $251 found 5 days ago
Delta
Sat, Oct 4 - Tue, Oct 21
PWM
Portland
DSM
Des Moines
$257 Roundtrip, found 5 days ago
$257
Roundtrip
found 5 days ago
Select Delta flight, departing Sat, Oct 4 from Portland to Des Moines, returning Tue, Oct 21, priced at $257 found 5 days ago
Delta
Sat, Oct 4 - Wed, Oct 8
PWM
Portland
DSM
Des Moines
$262 Roundtrip, found 5 days ago
$262
Roundtrip
found 5 days ago
Select Delta flight, departing Sat, Oct 4 from Portland to Des Moines, returning Wed, Oct 8, priced at $262 found 5 days ago
United
Wed, Oct 8 - Sat, Oct 11
PWM
Portland
DSM
Des Moines
$276 Roundtrip, found 5 days ago
$276
Roundtrip
found 5 days ago
Select United flight, departing Wed, Oct 8 from Portland to Des Moines, returning Sat, Oct 11, priced at $276 found 5 days ago
American Airlines
Wed, Oct 8 - Sat, Oct 11
PWM
Portland
DSM
Des Moines
$278 Roundtrip, found 5 days ago
$278
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Oct 8 from Portland to Des Moines, returning Sat, Oct 11, priced at $278 found 5 days ago
American Airlines
Wed, Oct 8 - Sat, Oct 11
PWM
Portland
DSM
Des Moines
$278 Roundtrip, found 5 days ago
$278
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Oct 8 from Portland to Des Moines, returning Sat, Oct 11, priced at $278 found 5 days ago
American Airlines
Wed, Oct 8 - Sat, Oct 11
PWM
Portland
DSM
Des Moines
$280 Roundtrip, found 5 days ago
$280
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Oct 8 from Portland to Des Moines, returning Sat, Oct 11, priced at $280 found 5 days ago
American Airlines
Wed, Oct 8 - Sat, Oct 11
PWM
Portland
DSM
Des Moines
$282 Roundtrip, found 5 days ago
$282
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Oct 8 from Portland to Des Moines, returning Sat, Oct 11, priced at $282 found 5 days ago
Southwest Airlines
Tue, Nov 18 - Mon, Nov 24
PWM
Portland
DSM
Des Moines
$322 Roundtrip, found 3 days ago
$322
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Tue, Nov 18 from Portland to Des Moines, returning Mon, Nov 24, priced at $322 found 3 days ago

Find the cheapest month to fly from Portland (PWM) to Des Moines (DSM)

August is typically the cheapest month to fly

From $230 - $626 per traveler.

Frequently asked questions

How much does a flight from Portland Intl. Jetport Airport (PWM) to Des Moines Intl. Airport (DSM) cost?
Get a cheap one-way flight from $129 or cheap return flight from $237 from Portland Intl. Jetport Airport (PWM) to Des Moines Intl. Airport (DSM) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Portland Intl. Jetport Airport (PWM) to Des Moines Intl. Airport (DSM)?
Flying in October is a good way to save, as it's the cheapest month for flights between PWM and DSM. You'll usually find the lowest prices during the off-season.
What is the cheapest airline that flies from Portland Intl. Jetport Airport (PWM) to Des Moines Intl. Airport (DSM)?
To find the cheapest airline flying from PWM to DSM, use Expedia's filter tool. Tailor your search based on your travel needs, such as preferred carriers and ideal departure window. You can then sort your results by "Price (lowest to highest)" to list the most affordable options first.
How many flights per day from Portland Intl. Jetport Airport (PWM) to Des Moines Intl. Airport (DSM)?
Nonstop flights from Portland Intl. Jetport Airport (PWM) to Des Moines Intl. Airport (DSM) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your travel details and pick either "1 Stop" or "2+ Stops."
What day of the week has the most flights from PWM to DSM?
Generally you'll find the largest variety of flight choices on a Friday. Tuesdays tend to be the quietest.* But this can change depending on the airline, season and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Portland Intl. Jetport Airport (PWM) to Des Moines Intl. Airport (DSM)?
To avoid potential delays on the Portland Intl. Jetport Airport (PWM) to Des Moines Intl. Airport (DSM) route, fly before 3 PM. Later flights have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Portland Intl. Jetport Airport (PWM) to Des Moines Intl. Airport (DSM) last-minute?
Booking your plane ticket from PWM to DSM shortly before your trip is usually more expensive. However, if there's some wiggle room with your departure dates and times, you could land a cheap last-minute fare.
Is it cheaper to book a PWM to DSM flight and hotel package?
You'll generally save money by booking a PWM to DSM flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one place. After choosing your ideal accommodations and flights, consider adding extras such as tours, car rentals and activities.
Can I cancel or change the date of my flight from Portland Intl. Jetport Airport (PWM) to Des Moines Intl. Airport (DSM)?
If you reserved your PWM to DSM flight in the last 24 hours, you may be able to cancel or modify it at no cost. Depending on the airline and the type of fare you have, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Travel information

Origin airport
Portland Intl. Jetport
Destination airport
Des Moines Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$237
Distance
1192 mi

Book with confidence

Book with confidence

Portland to Des Moines Flights

The cheapest times to fly from Portland to Des Moines

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Portland to Des Moines are during the month of October. You can find some of the cheapest flights from Portland to Des Moines with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Portland to Des Moines

Sunday is one of the best days to book for cheap flights from Portland to Des Moines: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Portland to Des Moines

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Portland to Des Moines in 2025. You can also book with separate airlines for your outbound and return journeys, from $129 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Portland to Des Moines flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Portland to Des Moines airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Portland to Des Moines Flights

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*Available to One Key members.