Title: 10 Best Motels in Southeast Missouri: Find Cheap Motels in Southeast Missouri 2026 - Expedia.com [Southeast Missouri Travel Guide](https://expedia.com/Southeast-Missouri.dx6058763)[Hotels in Southeast Missouri](https://expedia.com/Southeast-Missouri-Hotels.d6058763.Travel-Guide-Hotels)[Vacation Rentals in Southeast Missouri](https://expedia.com/Southeast-Missouri-Vacation-Rentals.d6058763.Travel-Guide-VacationRentals)[Flights to Southeast Missouri](https://expedia.com/Cheap-Flights-To-Southeast-Missouri.d6058763.Travel-Guide-Flights)[Things to do in Southeast Missouri](https://expedia.com/Things-To-Do-In-Southeast-Missouri.d6058763.Travel-Guide-Activities)[Car Rentals in Southeast Missouri](https://expedia.com/Car-Rentals-In-Southeast-Missouri.d6058763.Car-Rental-Guide)[Southeast Missouri Vacation Packages](https://expedia.com/Southeast-Missouri.d6058763.Destination-Travel-Guides) ![Mini Takes the States 2014 Road Rally Memphis to St.Louis Leg: Moark Regional Railroad Museum HOURS: Saturdays 1 p.m. - 4 p.m. It was not open when I stopped by but there are a few rail cars outside. Poplar has a train rich history. This was a cool little town to stop in and take pictures. Lot's of wall murals for some reason, and some very cool architecture. Worth the stop and be sure and enjoy a lunch at Hayden's Drive-In ! #MTTS2014 #minitakesthestates #go11 #train](https://images.trvl-media.com/place/9449/f87e8b74-cb32-40ea-afa8-0f245bfdc84b.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Bill Dillard ![](https://images.trvl-media.com/place/9449/f87e8b74-cb32-40ea-afa8-0f245bfdc84b.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_bundle_and_save.svg) ### Bundle & Save Get more, spend less whenever you see Bundle & Save deals - ![](https://a.travel-assets.com/travel-assets-manager/pictograms-expedia/light__onekey.svg) ### OneKeyCash Earn OneKeyCash on all your eligible bookings - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_ftc.svg) ### Upfront pricing We are not like the others - we include taxes and fees ## Check prices for these dates Next weekend [Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=6058763&startDate=2026-03-13&endDate=2026-03-15&adults=2&lodging=MOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=6058763&startDate=2026-03-20&endDate=2026-03-22&adults=2&lodging=MOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=6058763&startDate=2026-04-03&endDate=2026-04-05&adults=2&lodging=MOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [May 1 - May 3](https://www.expedia.com/Hotel-Search?regionId=6058763&startDate=2026-05-01&endDate=2026-05-03&adults=2&lodging=MOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Southeast Missouri motels ![Suite, 1 King Bed, Non Smoking (1 Bedroom) | In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/e270ba08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/504b77a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 King Bed, Accessible, Non Smoking (Mobility Accessible) | In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/ef8850d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/807f3a4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Perryville [](https://www.expedia.com/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) Perryville 8.4/10 Very Good (960 reviews) "If you're looking for a great deal, this is it. Unlike many less expensive hotels, this one has been refreshed with new carpeting and paint. Staff was courteous and friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Judith $68 nightly $78 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) ![Coffee service](https://images.trvl-media.com/lodging/16000000/15690000/15689200/15689127/22960908.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/16000000/15690000/15689200/15689127/a07fa840.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout drapes, free WiFi, bed sheets](https://images.trvl-media.com/lodging/16000000/15690000/15689200/15689127/15d55416.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/16000000/15690000/15689200/15689127/412c9f32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Poplar Bluff, MO [](https://www.expedia.com/Poplar-Bluff-Hotels-Motel-6-Poplar-Bluff.h15689127.Hotel-Information) Poplar Bluff 8.0/10 Very Good (1,005 reviews) "Very clean and staff was very friendly!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sherry $60 nightly $63 total Mar 9 - Mar 10 Total with taxes and fees [](https://www.expedia.com/Poplar-Bluff-Hotels-Motel-6-Poplar-Bluff.h15689127.Hotel-Information) ![Comfort Single Room | Individually decorated, individually furnished, blackout drapes](https://images.trvl-media.com/lodging/48000000/47040000/47039600/47039515/5e06e6ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/48000000/47040000/47039600/47039515/e6824269.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/48000000/47040000/47039600/47039515/708e4b63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/48000000/47040000/47039600/47039515/3b9c0313.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Current River Inn [](https://www.expedia.com/Van-Buren-Hotels-Current-River-Inn.h47039515.Hotel-Information) Van Buren 8.2/10 Very Good (167 reviews) "The mattresses were fabulous. Clean rooms and friendly staff. We will stay here again. The antique store and restaurants are walking distance. Nice family friendly establishment!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thad $95 nightly $103 total Mar 14 - Mar 15 Total with taxes and fees [](https://www.expedia.com/Van-Buren-Hotels-Current-River-Inn.h47039515.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/100000000/99810000/99804200/99804126/5ea95b39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/100000000/99810000/99804200/99804126/6ae8e98a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Room | Individually decorated, bed sheets](https://images.trvl-media.com/lodging/100000000/99810000/99804200/99804126/1e7471b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/100000000/99810000/99804200/99804126/57356935.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Black River Motel and Restaurant [](https://www.expedia.com/Lesterville-Hotels-Black-River-Motel-And-Restaurant.h99804126.Hotel-Information) Lesterville 8.4/10 Very Good (36 reviews) "This has been a great place to stay when we are traveling through Reynolds County MO." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael $129 nightly $136 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Lesterville-Hotels-Black-River-Motel-And-Restaurant.h99804126.Hotel-Information) ![Premier Room, 1 Bedroom, Non Smoking | Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/2d9e6936.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, free toiletries, towels, soap](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/1d8642af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Non Smoking | Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/a77daa89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premier Room, 1 Bedroom, Non Smoking | Bathroom | Combined shower/tub, free toiletries, towels, soap](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/5fa7b845.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### New Orleans Inn Portageville [](https://www.expedia.com/Hayti-Hotels-New-Orleans-Inn.h38979739.Hotel-Information) Portageville 8.0/10 Very Good (747 reviews) "Parking was good, staff was great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Corey $58 nightly $63 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Hayti-Hotels-New-Orleans-Inn.h38979739.Hotel-Information) ![Porch](https://images.trvl-media.com/lodging/1000000/60000/60000/59960/db122c9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/60000/60000/59960/765df2ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds | Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/60000/60000/59960/bca42102.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/60000/60000/59960/5f391186.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Madison Inn Lodge [](https://www.expedia.com/Farmington-Hotels-Madison-Inn-Lodge.h59960.Hotel-Information) Fredericktown 7.6/10 Good (297 reviews) "Friendly staff, and pricing, accommodating to our pets" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charlotte $88 nightly $96 total Mar 9 - Mar 10 Total with taxes and fees [](https://www.expedia.com/Farmington-Hotels-Madison-Inn-Lodge.h59960.Hotel-Information) ![Economy Single Room, 1 Queen Bed, Kitchenette | Private kitchen | Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/2ba6efa1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/2abc797b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/00115e7b_edited_b2b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Single Room, 1 Queen Bed, Kitchenette | Bathroom | Hair dryer, towels](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/324e501c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Town House Inn [](https://www.expedia.com/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) Jackson 7.6/10 Good (440 reviews) "The staff member Tim was very friendly and nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julie $68 nightly $74 total Mar 14 - Mar 15 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) ![Room, 1 King Bed, Non Smoking | View from room](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/183a17d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/ec6ce079.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/8720ff7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking | Bathroom | Hair dryer, towels](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/352edf3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Eagle Inn Charleston [](https://www.expedia.com/Sikeston-Hotels-Eagle-Inn-Charleston.h4480270.Hotel-Information) Charleston 6.6/10 (105 reviews) "Convenient " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marcelle $64 nightly $71 total Mar 9 - Mar 10 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Eagle-Inn-Charleston.h4480270.Hotel-Information) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/fa4ef12a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/980dd49e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/3798eaf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/b7350700.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Yard Inn and Suite [](https://www.expedia.com/Sikeston-Hotels-Country-Yard-Inn-And-Suite.h90821467.Hotel-Information) Sikeston 6.8/10 (126 reviews) "Great stay, numerous tv movie channels, check in easy, friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stanley $54 nightly $61 total Apr 1 - Apr 2 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Country-Yard-Inn-And-Suite.h90821467.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/860000/855800/855747/e565804d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/860000/855800/855747/e188e0c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/855800/855747/3343007d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Refrigerator | In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/860000/855800/855747/d7244881.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Farmington [](https://www.expedia.com/Farmington-Hotels-Super-8-By-Wyndham-Farmington.h855747.Hotel-Information) Farmington 8.0/10 Very Good (625 reviews) "Room was clean and good breakfast, not bad for the price " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cyle $60 nightly $68 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Farmington-Hotels-Super-8-By-Wyndham-Farmington.h855747.Hotel-Information) ![Desk, free WiFi](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/c3f8959c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/464a0039.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/2b1b1011.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking (NRF) | Desk, free WiFi](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/1f46462a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Town House Inn Cape Giradreau [](https://www.expedia.com/Sikeston-Hotels-Town-House-Inn-Cape-Giradreau.h11613884.Hotel-Information) Cape Girardeau 6.0/10 (212 reviews) "Along a main street but not a lot of noise, especially in the rooms. Rooms exit to the outdoors." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gary $66 nightly $74 total Apr 7 - Apr 8 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Town-House-Inn-Cape-Giradreau.h11613884.Hotel-Information) ![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/74000000/73620000/73612800/73612702/529899c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/74000000/73620000/73612800/73612702/13f4153b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/74000000/73620000/73612800/73612702/4ba5b1f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/74000000/73620000/73612800/73612702/86f0b1a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Bonne Terre, MO [](https://www.expedia.com/Bonne-Terre-Hotels-Motel-6-Bonne-Terre.h73612702.Hotel-Information) Bonne Terre 6.8/10 (33 reviews) "Yes very nice stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric $59 nightly $64 total Mar 14 - Mar 15 Total with taxes and fees [](https://www.expedia.com/Bonne-Terre-Hotels-Motel-6-Bonne-Terre.h73612702.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/440000/437700/437691/caa808f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/440000/437700/437691/8363a93f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/440000/437700/437691/e5416d3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/440000/437700/437691/cb936040.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Dexter [](https://www.expedia.com/Sikeston-Hotels-Econo-Lodge-Dexter.h437691.Hotel-Information) Dexter 6.8/10 (256 reviews) "The stay was very nice. Animal friendly, staff is super nice and house keeping is very respectful. I appreciate everyone. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle $51 nightly $57 total Apr 7 - Apr 8 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Econo-Lodge-Dexter.h437691.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/17000000/16580000/16575500/16575437/8f7cdde1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/17000000/16580000/16575500/16575437/9d4f4e63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/17000000/16580000/16575500/16575437/1f37faa9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Towels](https://images.trvl-media.com/lodging/17000000/16580000/16575500/16575437/b9e05884.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rosener's Inn and banquet center [](https://www.expedia.com/Farmington-Hotels-Roseners-Inn-And-Banquet-Center.h16575437.Hotel-Information) Park Hills 5.0/10 (48 reviews) "Not the cleanest place I've ever stayed, but you get what you pay for. If you expect pristine rooms, comfortable beds, clean towels, blankets and sheets, coffee makers, refrigerators and microwaves for $50 a night, you will be terribly disappointed. There is a reason the rooms aren't $150 per night. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brock $95 nightly $104 total Mar 16 - Mar 17 Total with taxes and fees [](https://www.expedia.com/Farmington-Hotels-Roseners-Inn-And-Banquet-Center.h16575437.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152272/1eb5943b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152272/81d44800.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152272/fb2e4094.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking | Bathroom | Free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152272/e9ec5dbd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### OYO Hickory House Inn [](https://www.expedia.com/Sikeston-Hotels-Hickory-House-Inn.h1152272.Hotel-Information) Dexter 5.6/10 (137 reviews) "We enjoyed every moment of our stay. Wonderful service—everyone was friendly and helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Albert $58 nightly $64 total Apr 7 - Apr 8 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Hickory-House-Inn.h1152272.Hotel-Information) ![Standard Room, 2 Queen Beds | In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/160000/158800/158717/245c686a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/160000/158800/158717/04ce172c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/160000/158800/158717/b3da6b1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/160000/158800/158717/79923507.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Potosi [](https://www.expedia.com/Farmington-Hotels-Super-8-By-Wyndham-Potosi.h158717.Hotel-Information) Potosi 7.0/10 Good (386 reviews) " Our stay was good. Employees were nice, room was clean, " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kenneth $55 nightly $60 total Mar 9 - Mar 10 Total with taxes and fees [](https://www.expedia.com/Farmington-Hotels-Super-8-By-Wyndham-Potosi.h158717.Hotel-Information) ![Laptop workspace, blackout drapes, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/679acee6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/a5038447.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/bbf96e9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/55ffcc39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Charleston/Sikeston East MO [](https://www.expedia.com/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) Charleston 6.8/10 (625 reviews) "Affordable for a quick one night stay. Restaurant and gas station next to hotel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Annette $62 nightly $69 total Mar 10 - Mar 11 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856300/856283/4bc8c9bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/860000/856300/856283/2099c0ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856300/856283/f80b85a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, blackout drapes, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/1000000/860000/856300/856283/2794fb89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Bonne Terre [](https://www.expedia.com/Farmington-Hotels-Super-8-By-Wyndham-Bonne-Terre.h856283.Hotel-Information) Bonne Terre 7.0/10 Good (550 reviews) "Rooms were clean, staff was very friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amy $58 nightly $63 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Farmington-Hotels-Super-8-By-Wyndham-Bonne-Terre.h856283.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/855400/855304/a26934b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/860000/855400/855304/3340c554.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/855400/855304/49fa46e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/860000/855400/855304/2b360823.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Poplar Bluff Missouri [](https://www.expedia.com/Poplar-Bluff-Hotels-Super-8-By-Wyndham-Poplar-Bluff-Missouri.h855304.Hotel-Information) Poplar Bluff 6.6/10 (636 reviews) "Very clean and staff was great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dawn $59 nightly $66 total Mar 28 - Mar 29 Total with taxes and fees [](https://www.expedia.com/Poplar-Bluff-Hotels-Super-8-By-Wyndham-Poplar-Bluff-Missouri.h855304.Hotel-Information) ![Desk, laptop workspace, blackout drapes, rollaway beds](https://images.trvl-media.com/lodging/1000000/860000/856200/856190/c6ce0eb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856200/856190/6ee208ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/856200/856190/e41ca8e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/860000/856200/856190/966cfbcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Pevely [](https://www.expedia.com/Farmington-Hotels-Super-8-By-Wyndham-Pevely.h856190.Hotel-Information) Pevely 5.6/10 (833 reviews) "Awesome " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) monica $76 nightly $87 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Farmington-Hotels-Super-8-By-Wyndham-Pevely.h856190.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-22&endDate=2026-03-23®ionId=6058763&adults=2&lodging=MOTEL&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=AA_SPRING_PROMO_6058763) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSoutheast-Missouri-Motels.d6058763-aaMotels.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSoutheast-Missouri-Motels.d6058763-aaMotels.Travel-Guide-Accommodation) ## Top Southeast Missouri Hotel Reviews ![Motel 6 Poplar Bluff, MO](https://images.trvl-media.com/lodging/16000000/15690000/15689200/15689127/22960908_y.jpg) ### Motel 6 Poplar Bluff, MO 10/10 Excellent "Did not use internet or shop" [](https://expedia.com/Poplar-Bluff-Hotels-Motel-6-Poplar-Bluff.h15689127.Hotel-Information) ![Drury Inn & Suites Cape Girardeau](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/6966efed_y.jpg) ### Drury Inn & Suites Cape Girardeau 10/10 Excellent "Great experience. We will pick Drury every time we travel. " [](https://expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![The Riverview](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg) ### The Riverview 10/10 Excellent "Friendly staff, very clean room. Love staying at this hotel!" [](https://expedia.com/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![The Farmstead Hotel](https://images.trvl-media.com/lodging/90000000/89310000/89303500/89303450/13275a81_y.jpg) ### The Farmstead Hotel 8/10 Good "The hotel appears fairly new and overall in good condition. Sheets and towels were clean, and the bed was comfortable. But whoever cleaned our room didn't do a good job. The carpet and armchair were dirty, there were smears on the nightstand and dirt and litter on the floor outside our door, there were crumbs on the desk chair, and the glass shower partition showed all kinds of drips and smears when it fogged up. However, it was dirty but not gross. And the person at the front desk was very helpful when we had trouble adjusting the heater. Also, the neighborhood around the hotel seemed kind of run down, but it didn't feel noisy or unsafe, and parking was convenient. " [](https://expedia.com/Caruthersville-Hotels-The-Farmstead.h89303450.Hotel-Information) ![Baymont Inn and Suites by Wyndham Farmington, MO](https://images.trvl-media.com/lodging/1000000/20000/16200/16153/02759b26_y.jpg) ### Baymont Inn and Suites by Wyndham Farmington, MO 4/10 Poor "Rooms are run down. Blanket had stains in it. Was given the wrong room at check in and got argued with on what i booked. Had to have my key reactivated on the 2nd night since they didnt put both nights in the syatem. Better to stay at another midgrade hotel." [](https://expedia.com/Farmington-Hotels-Baymont-Inn-And-Suites-By-Wyndham-Farmington.h16153.Hotel-Information) ![Drury Inn & Suites Sikeston, MO](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/85184a8e_y.jpg) ### Drury Inn & Suites Sikeston, MO 10/10 Excellent "Clean, comfortable room, plentiful parking, nice warm breakfast." [](https://expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Festus - St. Louis South](https://images.trvl-media.com/lodging/1000000/50000/42200/42120/6e70629c_y.jpg) ### La Quinta Inn & Suites by Wyndham Festus - St. Louis South 10/10 Excellent "The room was the cleanest that I have ever stayed in, in my life, totally spotless! The breakfast was very good, with alot of choices available!" [](https://expedia.com/Farmington-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Festus-St-Louis-South.h42120.Hotel-Information) ![Drury Plaza Hotel Cape Girardeau Conference Center](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/5929e46c_y.jpg) ### Drury Plaza Hotel Cape Girardeau Conference Center 10/10 Excellent "Clean room , nice staff" [](https://expedia.com/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/47fa1edf_y.jpg) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau 10/10 Excellent "Clean rooms. Friendly staff. " [](https://expedia.com/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ## Find out more about Southeast Missouri ## Southeast Missouri Motels information | Number of reviews | 7,973 | | ----------------- | --------- | | Accommodation | 26 Motels | | Lowest Price | $57 | | Highest Price | $104 | ## Frequently asked questions ### What is the nightly rate for a motel in Southeast Missouri? ### Is it better to stay in a Southeast Missouri motel or hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Hotels near Crane Lake Recreation Area ](https://www.expedia.com/Crane-Lake-Recreation-Area-Hotels.0-l6282499-0.Travel-Guide-Filter-Hotels) - [Des Arc Hotels ](https://www.expedia.com/Des-Arc-Hotels.d553248634983251690.Travel-Guide-Hotels) - [Hotels near Walnut Hollow Lake ](https://www.expedia.com/Walnut-Hollow-Lake-Hotels.0-l6282503-0.Travel-Guide-Filter-Hotels) - [Cabin Rentals in Annapolis ](https://www.expedia.com/Annapolis-Cabins.d6282465-aaCabins.Travel-Guide-Accommodation) - 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