Title: 10 Best Motels in Southeast Missouri: Find Cheap Motels in Southeast Missouri 2026 - Expedia.com [Southeast Missouri Travel Guide](https://expedia.com/Southeast-Missouri.dx6058763)[Hotels in Southeast Missouri](https://expedia.com/Southeast-Missouri-Hotels.d6058763.Travel-Guide-Hotels)[Vacation Rentals in Southeast Missouri](https://expedia.com/Southeast-Missouri-Vacation-Rentals.d6058763.Travel-Guide-VacationRentals)[Flights to Southeast Missouri](https://expedia.com/Cheap-Flights-To-Southeast-Missouri.d6058763.Travel-Guide-Flights)[Things to do in Southeast Missouri](https://expedia.com/Things-To-Do-In-Southeast-Missouri.d6058763.Travel-Guide-Activities)[Car Rentals in Southeast Missouri](https://expedia.com/Car-Rentals-In-Southeast-Missouri.d6058763.Car-Rental-Guide)[Southeast Missouri Vacation Packages](https://expedia.com/Southeast-Missouri.d6058763.Destination-Travel-Guides) ![Mini Takes the States 2014 Road Rally Memphis to St.Louis Leg: Moark Regional Railroad Museum HOURS: Saturdays 1 p.m. - 4 p.m. It was not open when I stopped by but there are a few rail cars outside. Poplar has a train rich history. This was a cool little town to stop in and take pictures. Lot's of wall murals for some reason, and some very cool architecture. Worth the stop and be sure and enjoy a lunch at Hayden's Drive-In ! #MTTS2014 #minitakesthestates #go11 #train](https://images.trvl-media.com/place/9449/f87e8b74-cb32-40ea-afa8-0f245bfdc84b.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Bill Dillard ![](https://images.trvl-media.com/place/9449/f87e8b74-cb32-40ea-afa8-0f245bfdc84b.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_bundle_and_save.svg) ### Bundle & Save Get more, spend less whenever you see Bundle & Save deals - ![](https://a.travel-assets.com/travel-assets-manager/pictograms-expedia/light__onekey.svg) ### OneKeyCash Earn OneKeyCash on all your eligible bookings - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_ftc.svg) ### Upfront pricing We are not like the others - we include taxes and fees ## Check prices for these dates Next weekend [Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=6058763&startDate=2026-03-13&endDate=2026-03-15&adults=2&lodging=MOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=6058763&startDate=2026-03-20&endDate=2026-03-22&adults=2&lodging=MOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=6058763&startDate=2026-04-03&endDate=2026-04-05&adults=2&lodging=MOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [May 1 - May 3](https://www.expedia.com/Hotel-Search?regionId=6058763&startDate=2026-05-01&endDate=2026-05-03&adults=2&lodging=MOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Southeast Missouri motels ![Suite, 1 King Bed, Non Smoking (1 Bedroom) | In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/e270ba08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/807f3a4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 King Bed, Accessible, Non Smoking (Mobility Accessible) | In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/badbf4c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/504b77a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Perryville [](https://www.expedia.com/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) Perryville 8.4/10 Very Good (958 reviews) "If you're looking for a great deal, this is it. Unlike many less expensive hotels, this one has been refreshed with new carpeting and paint. Staff was courteous and friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Judith $68 nightly $78 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) ![Coffee service](https://images.trvl-media.com/lodging/16000000/15690000/15689200/15689127/22960908.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout drapes, free WiFi, bed sheets](https://images.trvl-media.com/lodging/16000000/15690000/15689200/15689127/15d55416.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/16000000/15690000/15689200/15689127/412c9f32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchenette](https://images.trvl-media.com/lodging/16000000/15690000/15689200/15689127/8d2b66d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Poplar Bluff, MO [](https://www.expedia.com/Poplar-Bluff-Hotels-Motel-6-Poplar-Bluff.h15689127.Hotel-Information) Poplar Bluff 8.0/10 Very Good (1,004 reviews) "Very clean and staff was very friendly!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sherry $60 nightly $63 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Poplar-Bluff-Hotels-Motel-6-Poplar-Bluff.h15689127.Hotel-Information) ![Comfort Single Room | Individually decorated, individually furnished, blackout drapes](https://images.trvl-media.com/lodging/48000000/47040000/47039600/47039515/5e06e6ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Children's play area - outdoor](https://images.trvl-media.com/lodging/48000000/47040000/47039600/47039515/a1c79fe4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/48000000/47040000/47039600/47039515/3b9c0313.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/48000000/47040000/47039600/47039515/e6824269.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Current River Inn [](https://www.expedia.com/Van-Buren-Hotels-Current-River-Inn.h47039515.Hotel-Information) Van Buren 8.2/10 Very Good (167 reviews) "The mattresses were fabulous. Clean rooms and friendly staff. We will stay here again. The antique store and restaurants are walking distance. Nice family friendly establishment!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thad $95 nightly $103 total Mar 14 - Mar 15 Total with taxes and fees [](https://www.expedia.com/Van-Buren-Hotels-Current-River-Inn.h47039515.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/100000000/99810000/99804200/99804126/5ea95b39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/100000000/99810000/99804200/99804126/6ae8e98a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/100000000/99810000/99804200/99804126/57356935.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/100000000/99810000/99804200/99804126/7c676ce8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Black River Motel and Restaurant [](https://www.expedia.com/Lesterville-Hotels-Black-River-Motel-And-Restaurant.h99804126.Hotel-Information) Lesterville 8.4/10 Very Good (36 reviews) "This has been a great place to stay when we are traveling through Reynolds County MO." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael $99 nightly $105 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Lesterville-Hotels-Black-River-Motel-And-Restaurant.h99804126.Hotel-Information) ![Premier Room, 1 Bedroom, Non Smoking | Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/2d9e6936.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premier Room, 1 Bedroom, Non Smoking | Bathroom | Combined shower/tub, free toiletries, towels, soap](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/5fa7b845.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Non Smoking | Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/a77daa89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/91bb8871.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### New Orleans Inn Portageville [](https://www.expedia.com/Hayti-Hotels-New-Orleans-Inn.h38979739.Hotel-Information) Portageville 8.0/10 Very Good (747 reviews) "Parking was good, staff was great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Corey $58 nightly $63 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Hayti-Hotels-New-Orleans-Inn.h38979739.Hotel-Information) ![Porch](https://images.trvl-media.com/lodging/1000000/60000/60000/59960/db122c9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds | Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/60000/60000/59960/bca42102.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/60000/60000/59960/765df2ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/60000/60000/59960/622c9d52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Madison Inn Lodge [](https://www.expedia.com/Farmington-Hotels-Madison-Inn-Lodge.h59960.Hotel-Information) Fredericktown 7.6/10 Good (297 reviews) "Friendly staff, and pricing, accommodating to our pets" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charlotte $88 nightly $96 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Farmington-Hotels-Madison-Inn-Lodge.h59960.Hotel-Information) ![Economy Single Room, 1 Queen Bed, Kitchenette | Private kitchen | Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/2ba6efa1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/2abc797b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/00115e7b_edited_b2b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Single Room, 1 Queen Bed, Kitchenette | Bathroom | Hair dryer, towels](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/324e501c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Town House Inn [](https://www.expedia.com/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) Jackson 7.6/10 Good (440 reviews) "The staff member Tim was very friendly and nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julie $69 nightly $75 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) ![Room, 1 King Bed, Non Smoking | View from room](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/183a17d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/ec6ce079.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, alarm clocks](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/228b486a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking | Bathroom | Hair dryer, towels](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/352edf3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Eagle Inn Charleston [](https://www.expedia.com/Sikeston-Hotels-Eagle-Inn-Charleston.h4480270.Hotel-Information) Charleston 6.6/10 (105 reviews) "Convenient " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marcelle $64 nightly $71 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Eagle-Inn-Charleston.h4480270.Hotel-Information) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/fa4ef12a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/b7350700.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/980dd49e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/392abeff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Yard Inn and Suite [](https://www.expedia.com/Sikeston-Hotels-Country-Yard-Inn-And-Suite.h90821467.Hotel-Information) Sikeston 6.8/10 (126 reviews) "Great stay, numerous tv movie channels, check in easy, friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stanley $58 nightly $66 total Mar 13 - Mar 14 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Country-Yard-Inn-And-Suite.h90821467.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/860000/855800/855747/e565804d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/855800/855747/3343007d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/860000/855800/855747/32ba7ac0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/860000/855800/855747/e188e0c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Farmington [](https://www.expedia.com/Farmington-Hotels-Super-8-By-Wyndham-Farmington.h855747.Hotel-Information) Farmington 8.0/10 Very Good (625 reviews) "Room was clean and good breakfast, not bad for the price " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cyle $60 nightly $68 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Farmington-Hotels-Super-8-By-Wyndham-Farmington.h855747.Hotel-Information) ![Desk, free WiFi](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/c3f8959c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/f2b68c48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking (NRF) | Desk, free WiFi](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/1f46462a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/464a0039.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Town House Inn Cape Giradreau [](https://www.expedia.com/Sikeston-Hotels-Town-House-Inn-Cape-Giradreau.h11613884.Hotel-Information) Cape Girardeau 6.0/10 (211 reviews) "Along a main street but not a lot of noise, especially in the rooms. Rooms exit to the outdoors." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gary $66 nightly $74 total Apr 7 - Apr 8 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Town-House-Inn-Cape-Giradreau.h11613884.Hotel-Information) ![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/74000000/73620000/73612800/73612702/529899c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/74000000/73620000/73612800/73612702/13f4153b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/74000000/73620000/73612800/73612702/86f0b1a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/74000000/73620000/73612800/73612702/4ba5b1f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Bonne Terre, MO [](https://www.expedia.com/Bonne-Terre-Hotels-Motel-6-Bonne-Terre.h73612702.Hotel-Information) Bonne Terre 6.8/10 (33 reviews) "Yes very nice stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric $59 nightly $64 total Mar 13 - Mar 14 Total with taxes and fees [](https://www.expedia.com/Bonne-Terre-Hotels-Motel-6-Bonne-Terre.h73612702.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/440000/437700/437691/caa808f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/440000/437700/437691/8363a93f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/440000/437700/437691/e5416d3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/440000/437700/437691/cb936040.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Dexter [](https://www.expedia.com/Sikeston-Hotels-Econo-Lodge-Dexter.h437691.Hotel-Information) Dexter 6.8/10 (256 reviews) "The stay was very nice. Animal friendly, staff is super nice and house keeping is very respectful. I appreciate everyone. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle $51 nightly $57 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Econo-Lodge-Dexter.h437691.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/17000000/16580000/16575500/16575437/8f7cdde1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/17000000/16580000/16575500/16575437/1ba7cc90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/17000000/16580000/16575500/16575437/9d4f4e63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Towels](https://images.trvl-media.com/lodging/17000000/16580000/16575500/16575437/b9e05884.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rosener's Inn and banquet center [](https://www.expedia.com/Farmington-Hotels-Roseners-Inn-And-Banquet-Center.h16575437.Hotel-Information) Park Hills 5.0/10 (48 reviews) "Not the cleanest place I've ever stayed, but you get what you pay for. If you expect pristine rooms, comfortable beds, clean towels, blankets and sheets, coffee makers, refrigerators and microwaves for $50 a night, you will be terribly disappointed. There is a reason the rooms aren't $150 per night. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brock $95 nightly $104 total Mar 13 - Mar 14 Total with taxes and fees [](https://www.expedia.com/Farmington-Hotels-Roseners-Inn-And-Banquet-Center.h16575437.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152272/1eb5943b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152272/fb2e4094.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking | Bathroom | Free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152272/e9ec5dbd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152272/81d44800.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### OYO Hickory House Inn [](https://www.expedia.com/Sikeston-Hotels-Hickory-House-Inn.h1152272.Hotel-Information) Dexter 5.6/10 (137 reviews) "We enjoyed every moment of our stay. Wonderful service—everyone was friendly and helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Albert $58 nightly $64 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Hickory-House-Inn.h1152272.Hotel-Information) ![Standard Room, 2 Queen Beds | In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/160000/158800/158717/245c686a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/160000/158800/158717/79923507.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/160000/158800/158717/04ce172c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/160000/158800/158717/05c7ee11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Potosi [](https://www.expedia.com/Farmington-Hotels-Super-8-By-Wyndham-Potosi.h158717.Hotel-Information) Potosi 7.0/10 Good (386 reviews) " Our stay was good. Employees were nice, room was clean, " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kenneth $55 nightly $60 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Farmington-Hotels-Super-8-By-Wyndham-Potosi.h158717.Hotel-Information) ![Laptop workspace, blackout drapes, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/679acee6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/1ca277a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/bbf96e9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/a5038447.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Charleston/Sikeston East MO [](https://www.expedia.com/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) Charleston 6.8/10 (625 reviews) "Affordable for a quick one night stay. Restaurant and gas station next to hotel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Annette $62 nightly $69 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856300/856283/4bc8c9bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856300/856283/f80b85a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/860000/856300/856283/2099c0ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/860000/856300/856283/9d3ff163.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Bonne Terre [](https://www.expedia.com/Farmington-Hotels-Super-8-By-Wyndham-Bonne-Terre.h856283.Hotel-Information) Bonne Terre 7.0/10 Good (549 reviews) "Rooms were clean, staff was very friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amy $55 nightly $60 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Farmington-Hotels-Super-8-By-Wyndham-Bonne-Terre.h856283.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/855400/855304/a26934b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/860000/855400/855304/3340c554.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/860000/855400/855304/fefbc3f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/860000/855400/855304/2b360823.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Poplar Bluff Missouri [](https://www.expedia.com/Poplar-Bluff-Hotels-Super-8-By-Wyndham-Poplar-Bluff-Missouri.h855304.Hotel-Information) Poplar Bluff 6.6/10 (636 reviews) "Very clean and staff was great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dawn $55 nightly $62 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Poplar-Bluff-Hotels-Super-8-By-Wyndham-Poplar-Bluff-Missouri.h855304.Hotel-Information) ![Desk, laptop workspace, blackout drapes, rollaway beds](https://images.trvl-media.com/lodging/1000000/860000/856200/856190/c6ce0eb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 10:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/860000/856200/856190/31887483.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/860000/856200/856190/966cfbcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/856200/856190/e41ca8e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Pevely [](https://www.expedia.com/Farmington-Hotels-Super-8-By-Wyndham-Pevely.h856190.Hotel-Information) Pevely 5.6/10 (833 reviews) "Awesome " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) monica $71 nightly $81 total Mar 24 - Mar 25 Total with taxes and fees [](https://www.expedia.com/Farmington-Hotels-Super-8-By-Wyndham-Pevely.h856190.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-21&endDate=2026-03-22®ionId=6058763&adults=2&lodging=MOTEL&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=AA_SPRING_PROMO_6058763) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSoutheast-Missouri-Motels.d6058763-aaMotels.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSoutheast-Missouri-Motels.d6058763-aaMotels.Travel-Guide-Accommodation) ## Top Southeast Missouri Hotel Reviews ![La Quinta Inn & Suites by Wyndham Festus - St. Louis South](https://images.trvl-media.com/lodging/1000000/50000/42200/42120/6e70629c_y.jpg) ### La Quinta Inn & Suites by Wyndham Festus - St. Louis South 10/10 Excellent "The room was the cleanest that I have ever stayed in, in my life, totally spotless! The breakfast was very good, with alot of choices available!" [](https://expedia.com/Farmington-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Festus-St-Louis-South.h42120.Hotel-Information) ![The Farmstead Hotel](https://images.trvl-media.com/lodging/90000000/89310000/89303500/89303450/13275a81_y.jpg) ### The Farmstead Hotel 2/10 Terrible "Loud and unclean. Staff was rude " [](https://expedia.com/Caruthersville-Hotels-The-Farmstead.h89303450.Hotel-Information) ![The Riverview](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg) ### The Riverview 10/10 Excellent "Room was perfect" [](https://expedia.com/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Drury Plaza Hotel Cape Girardeau Conference Center](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/5929e46c_y.jpg) ### Drury Plaza Hotel Cape Girardeau Conference Center 10/10 Excellent "Clean room , nice staff" [](https://expedia.com/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/47fa1edf_y.jpg) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau 10/10 Excellent "Clean rooms. Friendly staff. " [](https://expedia.com/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f_y.jpg) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG 10/10 Excellent "Clean room staff is very nice parking it great " [](https://expedia.com/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![Baymont Inn and Suites by Wyndham Farmington, MO](https://images.trvl-media.com/lodging/1000000/20000/16200/16153/02759b26_y.jpg) ### Baymont Inn and Suites by Wyndham Farmington, MO 6/10 Okay "It's an ok place for the price to stay for one night. I would not count on a breakfast as it is one of the worst in my travel experience. Just skip it. " [](https://expedia.com/Farmington-Hotels-Baymont-Inn-And-Suites-By-Wyndham-Farmington.h16153.Hotel-Information) ![Drury Inn & Suites Jackson MO](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg) ### Drury Inn & Suites Jackson MO 10/10 Excellent "This was our first stay at a Drury hotel" [](https://expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Candlewood Suites Cape Girardeau by IHG](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/6afa6c85_y.jpg) ### Candlewood Suites Cape Girardeau by IHG 6/10 Okay "Pet friendly but charge a ridiculous amount of $75 Per pet!! Didn’t disclose untill check on. " [](https://expedia.com/Sikeston-Hotels-Candlewood-Suites-Cape-Girardeau.h3530303.Hotel-Information) ## Find out more about Southeast Missouri ## Southeast Missouri Motels information | Number of reviews | 7,968 | | ----------------- | --------- | | Accommodation | 26 Motels | | Lowest Price | $57 | | Highest Price | $104 | ## Frequently asked questions ### What is the nightly rate for a motel in Southeast Missouri? ### Is it better to stay in a Southeast Missouri motel or hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Hotels near Crane Lake Recreation Area ](https://www.expedia.com/Crane-Lake-Recreation-Area-Hotels.0-l6282499-0.Travel-Guide-Filter-Hotels) - [Des Arc Hotels ](https://www.expedia.com/Des-Arc-Hotels.d553248634983251690.Travel-Guide-Hotels) - [Hotels near Walnut Hollow Lake ](https://www.expedia.com/Walnut-Hollow-Lake-Hotels.0-l6282503-0.Travel-Guide-Filter-Hotels) - [Cabin Rentals in Annapolis ](https://www.expedia.com/Annapolis-Cabins.d6282465-aaCabins.Travel-Guide-Accommodation) - 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