Title: The Best 5 Star Hotels in Santa Clara, CA from $131 | Expedia.com

[Santa Clara Travel Guide](https://expedia.com/Santa-Clara.dx6172)[Hotels in Santa Clara](https://expedia.com/Santa-Clara-Hotels.d6172.Travel-Guide-Hotels)[Vacation Rentals in Santa Clara](https://expedia.com/Santa-Clara-Vacation-Rentals.d6172.Travel-Guide-VacationRentals)[Flights to Santa Clara](https://expedia.com/Cheap-Flights-To-Santa-Clara.d6172.Travel-Guide-Flights)[Things to do in Santa Clara](https://expedia.com/Things-To-Do-In-Santa-Clara.d6172.Travel-Guide-Activities)[Car Rentals in Santa Clara](https://expedia.com/Car-Rentals-In-Santa-Clara.d6172.Car-Rental-Guide)[Santa Clara Vacation Packages](https://expedia.com/Santa-Clara.d6172.Destination-Travel-Guides)

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## Check availability on Santa Clara 5 Star Hotels

Tonight

[Feb 19 - Feb 20](https://www.expedia.com/Hotel-Search?regionId=6172&startDate=2026-02-19&endDate=2026-02-20&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Feb 20 - Feb 21](https://www.expedia.com/Hotel-Search?regionId=6172&startDate=2026-02-20&endDate=2026-02-21&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Feb 20 - Feb 22](https://www.expedia.com/Hotel-Search?regionId=6172&startDate=2026-02-20&endDate=2026-02-22&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Feb 27 - Mar 1](https://www.expedia.com/Hotel-Search?regionId=6172&startDate=2026-02-27&endDate=2026-03-01&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

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## Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Santa Clara.

![The Domain Hotel](https://images.trvl-media.com/lodging/1000000/30000/21500/21433/2e56a61f_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### The Domain Hotel

1085 E El Camino Real Sunnyvale CA

$116 nightly

$131 total

Feb 21 - Feb 22

Total with taxes and fees

8.2/10 Very Good! (1,506 reviews)

[](https://expedia.com/Sunnyvale-Hotels-The-Domain-Hotel.h21433.Hotel-Information)

![Hyatt Regency Santa Clara](https://images.trvl-media.com/lodging/1000000/10000/4400/4313/d40e00b8_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hyatt Regency Santa Clara

5101 Great America Pkwy Santa Clara CA

$199 nightly

$235 total

Feb 21 - Feb 22

Total with taxes and fees

9/10 Wonderful! (1,003 reviews)

[](https://expedia.com/Santa-Clara-Hotels-Hyatt-Regency-Santa-Clara.h4313.Hotel-Information)

![Santa Clara Marriott](https://images.trvl-media.com/lodging/1000000/10000/6600/6542/38d72dbf_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Santa Clara Marriott

2700 Mission College Blvd Santa Clara CA

$143 nightly

$168 total

Feb 27 - Feb 28

Total with taxes and fees

8.8/10 Excellent! (1,002 reviews)

[](https://expedia.com/Santa-Clara-Hotels-Santa-Clara-Marriott.h6542.Hotel-Information)

Still don't see what you're looking for?

[See all properties in Santa Clara.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F21%2F2026&endDate=2%2F22%2F2026&regionId=6172&star=50)

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[Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F21%2F2026&endDate=2%2F22%2F2026&regionId=6172&star=50&star=50&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F21%2F2026&endDate=2%2F22%2F2026&regionId=6172&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F21%2F2026&endDate=2%2F22%2F2026&regionId=6172&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F21%2F2026&endDate=2%2F22%2F2026&regionId=6172&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F21%2F2026&endDate=2%2F22%2F2026&regionId=6172&star=50&star=50&amenities=WATER_PARK)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Learn more about Santa Clara

Tech enthusiasts flock to the Intel Museum and California's Great America theme park for thrills and innovation. Levi's Stadium hosts 49ers games, while nearby San Jose offers the Tech Museum of Innovation for curious minds.

[See all hotels in Santa Clara](https://www.expedia.com/Hotel-Search?startDate=2026-03-06&endDate=2026-03-07&adults=2&regionId=6172)

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## Top Santa Clara Hotel Reviews

## Find out more about Santa Clara

Why not ask for complete opulence during your trip to Santa Clara? After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Santa Clara so popular in the last year. There's no reason to delay a getaway to Santa Clara any longer. We should also mention, the hotels in this area receive high marks for guest services, so you know you'll be looked after during your getaway. Book one of Expedia's luxurious 5-star hotels in Santa Clara and get ready to be pampered like never before. What are you waiting for?

### 5-Star Hotels in Santa Clara

Don't be afraid to be pampered during your trip. High-end restaurants, concierges, and in-room spa sessions are all at the ready. You're sure to find exactly the accommodation you need. We should also mention, the hotels in this area receive fantastic marks for customer satisfaction, so you know you'll want for nothing during your getaway. What creature comforts do you want in your lodging? A reflexology treatment that will leave you feeling like a million bucks? 24-hour room service, so you can order that chocolate soufflé© in the wee hours of the morning? A rejuvenating facial treatment to help your cares fall away? 

You won't sleep and order room service the entire time, though. Don't worry. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what you end up doing, the 5-star hotels in Santa Clara are the perfect place to relax after an exciting day. Ready to learn more? Then explore the 910 reviews various guests have left on Expedia and get to know these places. 

### Your Getaway Starts Today

The results are in, and Santa Clara 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. It's time to plan your next great escape -- Expedia can help you land a great deal on accommodation. Opt for one of Expedia's Santa Clara 5-star hotels today and settle down in the lap of luxury when you're ready.

## Frequently asked questions

### What are the best 5-star hotels in Santa Clara?

### How much does it cost to stay in a 5-star hotel in Santa Clara?

> - Search for the lowest price per night from $131

### What makes a hotel 5 stars in Santa Clara?

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- [Harris-Lass Historic Museum ](https://www.expedia.com/Harris-Lass-Historic-Museum-Santa-Clara.d6063323.Vacation-Attraction)
- [Mission Santa Clara de Asis ](https://www.expedia.com/Mission-Santa-Clara-De-Asis-Santa-Clara.d6063313.Vacation-Attraction)
- [Santa Clara University ](https://www.expedia.com/Santa-Clara-University-Santa-Clara.d6063315.Vacation-Attraction)
- [Edward Peterman Museum of Railroad History ](https://www.expedia.com/Edward-Peterman-Museum-Of-Railroad-History-Santa-Clara.d6289450.Vacation-Attraction)
- [Winchester Mystery House ](https://www.expedia.com/Winchester-Mystery-House-West-San-Jose.d6069499.Vacation-Attraction)
- [Paypal Park ](https://www.expedia.com/PayPal-Park-Newhall.d553248621591293130.Vacation-Attraction)

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