Title: Best Depew, NY Lodge Rentals from $68 | Expedia.com [Depew Travel Guide](https://expedia.com/Depew.dx6338362)[Hotels in Depew](https://expedia.com/Depew-Hotels.d6338362.Travel-Guide-Hotels)[Vacation Rentals in Depew](https://expedia.com/Depew-Vacation-Rentals.d6338362.Travel-Guide-VacationRentals)[Flights to Depew](https://expedia.com/Cheap-Flights-To-Depew.d6338362.Travel-Guide-Flights)[Things to do in Depew](https://expedia.com/Things-To-Do-In-Depew.d6338362.Travel-Guide-Activities)[Car Rentals in Depew](https://expedia.com/Car-Rentals-In-Depew.d6338362.Car-Rental-Guide)[Depew Vacation Packages](https://expedia.com/Depew.d6338362.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_bundle_and_save.svg) ### Bundle & Save Get more, spend less whenever you see Bundle & Save deals - ![](https://a.travel-assets.com/travel-assets-manager/pictograms-expedia/light__onekey.svg) ### OneKeyCash Earn OneKeyCash on all your eligible bookings - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_ftc.svg) ### Upfront pricing We are not like the others - we include taxes and fees ## Check prices for these dates Next weekend [Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=6338362&startDate=2026-03-27&endDate=2026-03-29&adults=2&lodging=LODGE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=6338362&startDate=2026-04-03&endDate=2026-04-05&adults=2&lodging=LODGE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Apr 17 - Apr 19](https://www.expedia.com/Hotel-Search?regionId=6338362&startDate=2026-04-17&endDate=2026-04-19&adults=2&lodging=LODGE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [May 15 - May 17](https://www.expedia.com/Hotel-Search?regionId=6338362&startDate=2026-05-15&endDate=2026-05-17&adults=2&lodging=LODGE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) No exact matches found, but these alternatives could be just right ## Recommended hotels in Depew ![Interior](https://images.trvl-media.com/lodging/128000000/127200000/127194500/127194430/a07a74c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/128000000/127200000/127194500/127194430/bf112f42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/128000000/127200000/127194500/127194430/6af93d88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/128000000/127200000/127194500/127194430/015dbfc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 3-bedroom house in close to the airport Buffalo family- friendly no pets allowed [](https://www.expedia.com/Buffalo-Hotels-3-Bedroom-House-In-Close-To-The-Airport-Buffalo-Family-Friendly-No-Pets-Allowed.h127194430.Hotel-Information) Depew $240 nightly $268 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-3-Bedroom-House-In-Close-To-The-Airport-Buffalo-Family-Friendly-No-Pets-Allowed.h127194430.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567279/3274a349.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed | Premium bedding, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567279/a305e7d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567279/2685a465.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567279/3e0bf4eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Grand Island - Niagara Falls by IHG [](https://www.expedia.com/Niagara-Falls-Hotels-Holiday-Inn-Express-Grand-Island-Niagara-Falls.h18567279.Hotel-Information) Grand Island 9.0/10 Wonderful (1,724 reviews) "Large rooms, great breakfast, very friendly staff, location was great " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Diane $87 nightly $99 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Niagara-Falls-Hotels-Holiday-Inn-Express-Grand-Island-Niagara-Falls.h18567279.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/10000/5200/5183/46db5598.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Accessible, Refrigerator | Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/5200/5183/285a6583.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5200/5183/c135a4a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/5200/5183/73648063.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Summit Inn [](https://www.expedia.com/Niagara-Falls-Hotels-Best-Western-Summit-Inn.h5183.Hotel-Information) Niagara Falls 8.6/10 Excellent (1,442 reviews) "I stay at the Best Western Summit on March 18 to March 19 for one night. Ours stay was great the room was clean and nice also breakfast was good . I will definitely stay there again Maureen " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) MAUREEN $72 nightly $82 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Niagara-Falls-Hotels-Best-Western-Summit-Inn.h5183.Hotel-Information) ![Garden](https://images.trvl-media.com/lodging/8000000/7910000/7900500/7900412/1a361d5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Double Beds, Kitchen | Premium bedding, pillowtop beds, individually decorated](https://images.trvl-media.com/lodging/8000000/7910000/7900500/7900412/6cd5997e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/8000000/7910000/7900500/7900412/e8b3cf14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/8000000/7910000/7900500/7900412/c3686c83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clarence Inn [](https://www.expedia.com/Buffalo-Hotels-Clarence-Inn.h7900412.Hotel-Information) Clarence 8.2/10 Very Good (297 reviews) "Great service quiet place and friendly people." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Larry $99 nightly $111 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Clarence-Inn.h7900412.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/970000/968200/968172/2e04419a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed with Sofa bed, Non Smoking (King Study) | Hypo-allergenic bedding, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/970000/968200/968172/104f9b47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/970000/968200/968172/e8dba90d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/970000/968200/968172/8fe475d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn East Aurora [](https://www.expedia.com/East-Aurora-Hotels-Hampton-Inn-East-Aurora.h968172.Hotel-Information) East Aurora 9.4/10 Exceptional (1,001 reviews) "Incredibly friendly staff at check in. Room was beautiful and very clean. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Linda $130 nightly $148 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/East-Aurora-Hotels-Hampton-Inn-East-Aurora.h968172.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/100000000/99810000/99802700/99802648/b3c0a8a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking (with Sofabed) | Individually furnished, desk, laptop workspace, free WiFi](https://images.trvl-media.com/lodging/100000000/99810000/99802700/99802648/1eafede6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/100000000/99810000/99802700/99802648/dec807b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/100000000/99810000/99802700/99802648/4eac0a0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Buffalo Inn & Suites [](https://www.expedia.com/Eva-Hotel.h99802648.Hotel-Information) Buffalo 8.8/10 Excellent (898 reviews) "Front desk staff are always amazing. Simple, fast check-in and check out, very friendly." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Akousa $100 nightly $114 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Eva-Hotel.h99802648.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/10000000/9750000/9743100/9743017/27ee7ea2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/10000000/9750000/9743100/9743017/a36a3e4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/10000000/9750000/9743100/9743017/ed49d5cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Non Smoking (Whirlpool Tub) | In-room safe, desk, laptop workspace, soundproofing](https://images.trvl-media.com/lodging/10000000/9750000/9743100/9743017/9bd79013.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Salvatores Grand Hotel [](https://www.expedia.com/Buffalo-Hotels-Salvatores-Grand-Hotel.h9743017.Hotel-Information) Buffalo 9.6/10 Exceptional (1,000 reviews) "It was beautiful and staff was wonderful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sherry $129 nightly $147 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Salvatores-Grand-Hotel.h9743017.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/94000000/93470000/93463700/93463671/c4fa613a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/94000000/93470000/93463700/93463671/f8a867f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/94000000/93470000/93463700/93463671/c8535cdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/94000000/93470000/93463700/93463671/b2b973f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 420 Friendly 3 bedroom upstairs apartment. Street parking only. [](https://www.expedia.com/Buffalo-Hotels-420-Friendly-3-Bedroom-Upstairs-Apartment-Street-Parking-Only.h93463671.Hotel-Information) Seneca 9.4/10 Exceptional (68 reviews) "Excellent stay! All the things we needed and then some :) highly recommend! Will be staying here anytime I am in the area!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kerry G. $190 nightly $194 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-420-Friendly-3-Bedroom-Upstairs-Apartment-Street-Parking-Only.h93463671.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/8000000/7520000/7511900/7511809/2864591b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/8000000/7520000/7511900/7511809/7ff31af2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Suite, 1 Bedroom | Premium bedding, pillowtop beds, individually furnished, desk](https://images.trvl-media.com/lodging/8000000/7520000/7511900/7511809/1c0281cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/8000000/7520000/7511900/7511809/94dc4133.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Roycroft Inn [](https://www.expedia.com/East-Aurora-Hotels-Roycroft-Inn.h7511809.Hotel-Information) East Aurora 9.6/10 Exceptional (864 reviews) "Beautiful & historic inn with a wonderful staff & restaurant. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen $149 nightly $166 total Apr 16 - Apr 17 Total with taxes and fees [](https://www.expedia.com/East-Aurora-Hotels-Roycroft-Inn.h7511809.Hotel-Information) ![Standard Studio Suite, 1 King Bed, Jetted Tub | In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/8000000/7670000/7663400/7663327/18b8438d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/8000000/7670000/7663400/7663327/f038d62d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Studio Suite, 1 King Bed, Jetted Tub | In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/8000000/7670000/7663400/7663327/44216c33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/8000000/7670000/7663400/7663327/8334e598.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lockport Inn & Suites [](https://www.expedia.com/Niagara-Falls-Hotels-Lockport-Inn-Suites.h7663327.Hotel-Information) Lockport 9.2/10 Wonderful (1,000 reviews) "Very nice family-run cozy stay." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Leonardo $99 nightly $112 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Niagara-Falls-Hotels-Lockport-Inn-Suites.h7663327.Hotel-Information) ![Standard Room, 1 King Bed, Non Smoking (Ground Floor, Pets Allowed) | 1 bedroom, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/2100/2071/fc11b7d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/2100/2071/b47b27ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/2100/2071/a26a08df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/2100/2071/19db4ac2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Darien Lakes [](https://www.expedia.com/Corfu-Hotels-Econo-Lodge-Darien-Lakes.h2071.Hotel-Information) Corfu 7.8/10 Good (812 reviews) "Staff were prompt with check-in and very direct. It was helpful. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anna $68 nightly $75 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Corfu-Hotels-Econo-Lodge-Darien-Lakes.h2071.Hotel-Information) ![Deluxe Room, 2 Queen Beds, Non Smoking | Desk, iron/ironing board, free cribs/infant beds, rollaway beds](https://images.trvl-media.com/lodging/2000000/1500000/1497100/1497090/00561ac2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1500000/1497100/1497090/0f06dafe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1500000/1497100/1497090/af522590.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1500000/1497100/1497090/74836d03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn & Suites by Wyndham Niagara Falls/Buffalo [](https://www.expedia.com/Niagara-Falls-Hotels-Days-Inn-Suites-By-Wyndham-Niagara-Fallsbuffalo.h1497090.Hotel-Information) Niagara Falls 8.0/10 Very Good (1,003 reviews) "Wonderful stay will stay again" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) christine $68 nightly $77 total Mar 30 - Mar 31 Total with taxes and fees [](https://www.expedia.com/Niagara-Falls-Hotels-Days-Inn-Suites-By-Wyndham-Niagara-Fallsbuffalo.h1497090.Hotel-Information) ![Fireplace](https://images.trvl-media.com/lodging/74000000/73420000/73412100/73412050/b95ee62f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![The Madison Suite | Bathroom | Shower, hair dryer, towels, soap](https://images.trvl-media.com/lodging/74000000/73420000/73412100/73412050/039a8e7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/74000000/73420000/73412100/73412050/3e59eb6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/74000000/73420000/73412100/73412050/6a75ba52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Edward Hotel [](https://www.expedia.com/Buffalo-Hotels-The-Edward-Hotel.h73412050.Hotel-Information) Elmwood Village 9.6/10 Exceptional (227 reviews) "The Edward is quaint and in walking distance to many restaurants and shops. We had a wonderful stay. It’s very clean and all of the rooms are unique in their design which added to the pleasure of our stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shannon $134 nightly $154 total Mar 24 - Mar 25 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-The-Edward-Hotel.h73412050.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/560000/558600/558591/139ee991.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking | Premium bedding, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/560000/558600/558591/2a472ad1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/560000/558600/558591/a196e14b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business center](https://images.trvl-media.com/lodging/1000000/560000/558600/558591/295249d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Near Walden Galleria Mall [](https://www.expedia.com/Buffalo-Hotels-Quality-Inn-Near-Walden-Galleria-Mall.h558591.Hotel-Information) Buffalo 8.0/10 Very Good (1,002 reviews) "Good location for our visit for a concert at Keybank. Room was clean, bed was comfortable." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Melissa $84 nightly $96 total Apr 2 - Apr 3 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Quality-Inn-Near-Walden-Galleria-Mall.h558591.Hotel-Information) ![Suite, 1 King Bed with Sofa bed, Non Smoking | Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/90000/85100/85007/9d03cce3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, Non Smoking (2 Double Beds & Sofa Bed) | Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/90000/85100/85007/278a83c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/90000/85100/85007/77375700.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/85100/85007/ae021a7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn & Suites Buffalo Airport [](https://www.expedia.com/Buffalo-Hotels-Sleep-Inn-Suites-Buffalo-Airport.h85007.Hotel-Information) Buffalo 8.0/10 Very Good (2,015 reviews) "Nice hotel" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Nilanjan $75 nightly $86 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Sleep-Inn-Suites-Buffalo-Airport.h85007.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/48000000/47030000/47021400/47021354/09462364.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/48000000/47030000/47021400/47021354/17eab8f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/48000000/47030000/47021400/47021354/5de7a4e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/48000000/47030000/47021400/47021354/7ab4a0dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Amherst - Lockport by IHG [](https://www.expedia.com/Buffalo-Hotels-Holiday-Inn-Express-Lockport.h47021354.Hotel-Information) Lockport 9.2/10 Wonderful (765 reviews) "Clean and comfortable accommodations, friendly staff and a great breakfast spread!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrea $111 nightly $125 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Holiday-Inn-Express-Lockport.h47021354.Hotel-Information) ![Deluxe Room, 2 Double Beds (Smoke Free) | 1 bedroom, desk, blackout drapes, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/900/816/dec8cb3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/900/816/760d0b9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/900/816/b68133b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, blackout drapes, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/900/816/d1c4663a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Buffalo - Niagara Airport [](https://www.expedia.com/Buffalo-Hotels-Red-Roof-Inn-Buffalo-Niagara-Airport.h816.Hotel-Information) Bowmansville 7.2/10 Good (1,001 reviews) "Parking was easy. Room was clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gary $60 nightly $69 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Red-Roof-Inn-Buffalo-Niagara-Airport.h816.Hotel-Information) ![Lunch and dinner served, American cuisine](https://images.trvl-media.com/lodging/1000000/30000/26100/26001/19bd0f50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed with Sofa bed | In-room safe, desk, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/26100/26001/52bfdeb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/30000/26100/26001/12050768.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26100/26001/e6ba9cfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Buffalo Airport Hotel [](https://www.expedia.com/Buffalo-Hotels-Buffalo-Airport-Hotel.h26001.Hotel-Information) Buffalo 8.0/10 Very Good (2,909 reviews) "Great stay for the price !!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elizabeth $85 nightly $97 total Mar 26 - Mar 27 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Buffalo-Airport-Hotel.h26001.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/10000000/9680000/9680000/9679916/b02fadd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/10000000/9680000/9680000/9679916/72bc6212.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/10000000/9680000/9680000/9679916/382726c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/10000000/9680000/9680000/9679916/3f52c531.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AAshram Hotel by Niagara River [](https://www.expedia.com/Niagara-Falls-Hotels-AAshram-Hotel-By-Niagara-River.h9679916.Hotel-Information) La Salle 7.8/10 Good (1,000 reviews) "Very clean & wide room. Close to the falls & market. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Hari Reshma $59 nightly $68 total Apr 1 - Apr 2 Total with taxes and fees [](https://www.expedia.com/Niagara-Falls-Hotels-AAshram-Hotel-By-Niagara-River.h9679916.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/19000000/18140000/18136300/18136290/3791ed95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room (Cozy, Full/Full) | Hypo-allergenic bedding, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/19000000/18140000/18136300/18136290/739fabc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/19000000/18140000/18136300/18136290/0f54e2f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/19000000/18140000/18136300/18136290/9874aa4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Richardson Hotel [](https://www.expedia.com/Buffalo-Hotels-Hotel-Henry-Urban-Resort.h18136290.Hotel-Information) Elmwood Bidwell 9.0/10 Wonderful (1,003 reviews) "Nice place, excellent breakfast service" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sean $147 nightly $172 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Hotel-Henry-Urban-Resort.h18136290.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-05&endDate=2026-04-06®ionId=6338362&adults=2&lodging=LODGE&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDepew-Lodges.d6338362-aaLodges.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDepew-Lodges.d6338362-aaLodges.Travel-Guide-Accommodation) ## Top Depew Hotel Reviews ![Aloft Buffalo Airport](https://images.trvl-media.com/lodging/10000000/9280000/9277900/9277828/9352f0af_y.jpg) ### Aloft Buffalo Airport 10/10 Excellent "We were beyond thrilled with our visit! The staff was over the top excellent! Super friendly and helpful. We felt like we were at home and every single day they went above and beyond to help us have an amazing stay. The girls at front desk and the shuttle driver all made our stay the best. We can’t wait to come back! " [](https://expedia.com/Buffalo-Hotels-Aloft-Buffalo-Airport.h9277828.Hotel-Information) ![Garden Place Hotel](https://images.trvl-media.com/lodging/2000000/1070000/1060800/1060721/40afc3e4_y.jpg) ### Garden Place Hotel 4/10 Poor "Staff was excellent, wi-fi was really bad, toilet kept running, someone came to repair it, but still wasn't working properly. " [](https://expedia.com/Buffalo-Hotels-Garden-Place-Hotel.h1060721.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Buffalo Amherst](https://images.trvl-media.com/lodging/25000000/24730000/24723600/24723591/6499bfe4_y.jpg) ### La Quinta Inn & Suites by Wyndham Buffalo Amherst 8/10 Good "all good!" [](https://expedia.com/Buffalo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Buffalo-Amherst.h24723591.Hotel-Information) ![Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG](https://images.trvl-media.com/lodging/1000000/980000/973800/973773/ee46454f_y.jpg) ### Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG 8/10 Good "Yes" [](https://expedia.com/Buffalo-Hotels-Holiday-Inn-Express-Hotel-Suites-Buffalo-Airport.h973773.Hotel-Information) ![Wyndham Garden Buffalo Downtown](https://images.trvl-media.com/lodging/1000000/160000/159000/158959/dfd9177e_y.jpg) ### Wyndham Garden Buffalo Downtown 8/10 Good "Hotel is good. Located around hospitals in downtown. Relatively old and facilities might need some remodeling. Overall a good hotel if you are looking in that area. " [](https://expedia.com/Buffalo-Hotels-Wyndham-Garden-Buffalo-Downtown.h158959.Hotel-Information) ![Holiday Inn Express Grand Island - Niagara Falls by IHG](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567279/3274a349_y.jpg) ### Holiday Inn Express Grand Island - Niagara Falls by IHG 10/10 Excellent "Clean rooms, clean bathrooms, nice saltwater pool, friendly breakfast and front desk staff. We would stay again! " [](https://expedia.com/Niagara-Falls-Hotels-Holiday-Inn-Express-Grand-Island-Niagara-Falls.h18567279.Hotel-Information) ![Buffalo Airport Hotel](https://images.trvl-media.com/lodging/1000000/30000/26100/26001/19bd0f50_y.jpg) ### Buffalo Airport Hotel 8/10 Good "GREAT for shuttle service. Only coffee in morning." [](https://expedia.com/Buffalo-Hotels-Buffalo-Airport-Hotel.h26001.Hotel-Information) ![Microtel Inn & Suites by Wyndham Niagara Falls](https://images.trvl-media.com/lodging/17000000/16350000/16348700/16348639/b9a48adb_y.jpg) ### Microtel Inn & Suites by Wyndham Niagara Falls 8/10 Good "The hotel was clean comfortable beds. Breakfast wasn’t great but price we paid can’t complain. Staff were friendly. Really om was immaculately clean. Amenities in room were great Will definitely return " [](https://expedia.com/Niagara-Falls-Hotels-Microtel-Inn-Suites-By-Wyndham-Niagara-Falls.h16348639.Hotel-Information) ![La Quinta Inn by Wyndham Buffalo Airport](https://images.trvl-media.com/lodging/1000000/30000/27600/27531/86fc2ca1_y.jpg) ### La Quinta Inn by Wyndham Buffalo Airport 6/10 Okay "The staff were very good, friendly and engaging. However our room smelled of cigarette smoke, even though it was clean it smelled awful. location is good, staff were good and the breakfast was ok." [](https://expedia.com/Buffalo-Hotels-La-Quinta-Inn-By-Wyndham-Buffalo-Airport.h27531.Hotel-Information) ## Find out more about Depew ## Depew Lodges information | Number of reviews | 21,173 | | ----------------- | -------- | | Accommodation | 1 Lodges | | Lowest Price | $68 | | Highest Price | $172 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Hotels near Reinstein Woods Nature Preserve and Environmental Education Center ](https://www.expedia.com/Reinstein-Woods-Nature-Preserve-And-Environmental-Education-Center-Hotels.0-l553248621561173660-0.Travel-Guide-Filter-Hotels) - [Hotels near Buffalo-Depew Station ](https://www.expedia.com/Buffalo-Depew-Station-Hotels.d6194293.Travel-Guide-Hotels) - [Hotels near Buffalo Niagara Intl. ](https://www.expedia.com/Buffalo-Niagara-Intl-Airport-Hotels.0-aBUF-0.Travel-Guide-Filter-Hotels) - [Hotels near Stiglmeier Park ](https://www.expedia.com/Stiglmeier-Park-Hotels.0-l553248621558133903-0.Travel-Guide-Filter-Hotels) - 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