Title: Panama Non-Smoking Hotels from $69 - Fully Refundable Options - Expedia.com

[Panama Travel Guide](https://expedia.com/Panama.dx142)[Panama Hotels](https://expedia.com/Destinations-In-Panama.d142.Hotel-Destinations)[Vacation Rentals in Panama](https://expedia.com/Destinations-In-Panama.d142.Vacation-Rental-Destinations)[Panama Flights](https://expedia.com/Destinations-In-Panama.d142.Flight-Destinations)[Car Rentals in Panama](https://expedia.com/Destinations-In-Panama.d142.Car-Rental-Destinations)[Panama Vacations](https://expedia.com/Panama.d142.Destination-Travel-Guides)

![Panama featuring landscape views, tropical scenes and island images](https://images.trvl-media.com/place/142/329febe6-4cd6-48f7-a9e8-71ea862bef81.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by PhotoJoy

![](https://images.trvl-media.com/place/142/329febe6-4cd6-48f7-a9e8-71ea862bef81.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Top Cities in Panama

![](https://mediaim.expedia.com/destination/1/1916fc53ea2cb142bbaeb7b9e6efaf16.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### Panama City

[](https://expedia.com/Panama-City-Hotels-Smoke-Free-Hotels.0-0-d2897-tSmokeFreeHotels.Travel-Guide-Filter-Hotels)

![](https://mediaim.expedia.com/destination/1/25f99a393b969b3735c64d4b492225c8.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### Bocas del Toro

[](https://expedia.com/Bocas-Del-Toro-Hotels-Smoke-Free-Hotels.0-0-d6023445-tSmokeFreeHotels.Travel-Guide-Filter-Hotels)

## Check availability on Panama Non-Smoking Hotels

Tonight

[Feb 24 - Feb 25](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-02-24&endDate=2026-02-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Feb 25 - Feb 26](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-02-25&endDate=2026-02-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Feb 27 - Mar 1](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-02-27&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Mar 6 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Panama non-smoking hotels

![Beach nearby](https://images.trvl-media.com/lodging/19000000/18840000/18839300/18839207/0b87514e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/19000000/18840000/18839300/18839207/c7b3b49f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/19000000/18840000/18839300/18839207/d62404a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/19000000/18840000/18839300/18839207/1ff29ce5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 1st Floor Beach House Apartment just steps from the beach!

[](https://www.expedia.com/Las-Tablas-Hotels-1st-Floor-Beach-House-Apartment-Just-Steps-From-The-Beach.h18839207.Hotel-Information)

Las Tablas

9.4/10

Exceptional

(6 reviews)

"Although my visit was short the property had everything needed for a wonderful stay. The property manager was extremely helpful."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Deborah I.

[](https://www.expedia.com/Las-Tablas-Hotels-1st-Floor-Beach-House-Apartment-Just-Steps-From-The-Beach.h18839207.Hotel-Information)

![Beach nearby](https://images.trvl-media.com/lodging/19000000/18840000/18839500/18839466/0e658cfc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/19000000/18840000/18839500/18839466/2a78506f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/19000000/18840000/18839500/18839466/e77096ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/19000000/18840000/18839500/18839466/5f4b979e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 2 Story 3 Bed/2 Bath House with separate units just steps from the beach!!

[](https://www.expedia.com/Las-Tablas-Hotels-2-Story-Beach-House-Just-Steps-From-The-Beach.h18839466.Hotel-Information)

Las Tablas

9.6/10

Exceptional

(4 reviews)

"Nice beach access "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

jay

[](https://www.expedia.com/Las-Tablas-Hotels-2-Story-Beach-House-Just-Steps-From-The-Beach.h18839466.Hotel-Information)

![2 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/19000000/18840000/18839600/18839580/119b378b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/19000000/18840000/18839600/18839580/712bd3c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, DVD player](https://images.trvl-media.com/lodging/19000000/18840000/18839600/18839580/f4008080.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/19000000/18840000/18839600/18839580/08653042.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 2nd Floor Beach House Apartment just steps from the beach!

[](https://www.expedia.com/Las-Tablas-Hotels-2nd-Floor-Beach-House-Apartment-Just-Steps-From-The-Beach.h18839580.Hotel-Information)

Las Tablas

8.6/10

Excellent

(4 reviews)

"Fully furnished. Newly remodeled. Very quiet. Bring your own beach chairs. Good shelling at low tide! Enjoy!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Archie L.

[](https://www.expedia.com/Las-Tablas-Hotels-2nd-Floor-Beach-House-Apartment-Just-Steps-From-The-Beach.h18839580.Hotel-Information)

![Rooftop terrace](https://images.trvl-media.com/lodging/13000000/12890000/12880400/12880383/043c855c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/13000000/12890000/12880400/12880383/d365d94c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 Bedroom | Living area | Flat-screen TV, iPod dock](https://images.trvl-media.com/lodging/13000000/12890000/12880400/12880383/b15efcd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lounge](https://images.trvl-media.com/lodging/13000000/12890000/12880400/12880383/d13c98d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### AC Hotel by Marriott Panama City

[](https://www.expedia.com/Panama-City-Hotels-AC-Hotel-By-Marriott-Panama-City.h12880383.Hotel-Information)

Bella Vista

8.8/10

Excellent

(776 reviews)

"The staff was exceptional and the room was great. Best stay in my life. 100% recommended"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Javanny

$112 nightly

$123 total

Mar 22 - Mar 23

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-AC-Hotel-By-Marriott-Panama-City.h12880383.Hotel-Information)

![Interior detail](https://images.trvl-media.com/lodging/2000000/1420000/1410100/1410051/194428d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/2000000/1420000/1410100/1410051/9bc48ad2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Garden](https://images.trvl-media.com/lodging/2000000/1420000/1410100/1410051/995a9fa7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Double Room, 2 Double Beds | Premium bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/2000000/1420000/1410100/1410051/8ab07dee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Albrook Inn

[](https://www.expedia.com/Panama-City-Hotels-Albrook-Inn.h1410051.Hotel-Information)

Panama City

7.8/10

Good

(583 reviews)

"Friendly front desk staff, comfortable bed, close proximity to airport"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Hildi

$63 nightly

$69 total

Feb 26 - Feb 27

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-Albrook-Inn.h1410051.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/7000000/6580000/6577500/6577427/75c7ddd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/7000000/6580000/6577500/6577427/8c2779b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/7000000/6580000/6577500/6577427/590df444.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/7000000/6580000/6577500/6577427/02a8cee5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aloft Panama

[](https://www.expedia.com/Panama-City-Hotels-Aloft-Panama.h6577427.Hotel-Information)

San Francisco

8.6/10

Excellent

(969 reviews)

"Perfect stay for a few days at Panama!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Maria

$119 nightly

$131 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-Aloft-Panama.h6577427.Hotel-Information)

![Breakfast, lunch served; local and international cuisine, garden views ](https://images.trvl-media.com/lodging/7000000/6420000/6417200/6417143/c3192737.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/7000000/6420000/6417200/6417143/af7444f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/7000000/6420000/6417200/6417143/89b00dea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/7000000/6420000/6417200/6417143/3caa6f92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### American Trade Hotel

[](https://www.expedia.com/Panama-City-Hotels-American-Trade-Hotel.h6417143.Hotel-Information)

Casco Viejo

9.4/10

Exceptional

(663 reviews)

"Perfect location with attentive staff and nice rooms"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Negar

$225 nightly

$250 total

Mar 4 - Mar 5

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-American-Trade-Hotel.h6417143.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1860000/1855400/1855396/d94a299c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cabin | Private kitchen](https://images.trvl-media.com/lodging/2000000/1860000/1855400/1855396/58f20ea0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, premium bedding, blackout drapes, free cribs/infant beds](https://images.trvl-media.com/lodging/2000000/1860000/1855400/1855396/0e1dfc23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior entrance](https://images.trvl-media.com/lodging/2000000/1860000/1855400/1855396/65de3fea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Anton Valley Hotel

[](https://www.expedia.com/El-Valle-De-Anton-Hotels-Anton-Valley-Hotel.h1855396.Hotel-Information)

El Valle de Anton

7.8/10

Good

(68 reviews)

"Very central with a restaurant and spa. Big room with kitchen"

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Donna

[](https://www.expedia.com/El-Valle-De-Anton-Hotels-Anton-Valley-Hotel.h1855396.Hotel-Information)

![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/10000000/9820000/9810500/9810426/001e44b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/10000000/9820000/9810500/9810426/6fd41e9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/10000000/9820000/9810500/9810426/9246a1c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/10000000/9820000/9810500/9810426/8e04e5d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aranjuez Hotel & Suites

[](https://www.expedia.com/David-Hotels-Aranjuez-Hotel-Suites.h9810426.Hotel-Information)

David Sur

9.2/10

Wonderful

(798 reviews)

"Wonderful staff & great restaurant"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

KAREN

$67 nightly

$75 total

Feb 27 - Feb 28

Total with taxes and fees

[](https://www.expedia.com/David-Hotels-Aranjuez-Hotel-Suites.h9810426.Hotel-Information)

![Dining](https://images.trvl-media.com/lodging/16000000/15990000/15982300/15982263/76f4e974.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free toiletries, towels](https://images.trvl-media.com/lodging/16000000/15990000/15982300/15982263/f9404c92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/16000000/15990000/15982300/15982263/c206981c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/16000000/15990000/15982300/15982263/b7d94b85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Autana Bed and Breakfast - Hostel

[](https://www.expedia.com/Boquete-Hotels-Autana-Bed-And-Breakfast-Hostel.h15982263.Hotel-Information)

Los Naranjos

7.2/10

Good

(5 reviews)

"Endroit calme un peu à l'écart de la ville et donc nécessitant d'avoir une voiture. L'endroit est une belle découverte. Certes, c'est un peu rustique mais la personne qui s'occupe de l'endroit est vraiment extrêmement gentil et serviable. C'est une belle surprise... rustique mais vraiment sympa. Autre point, on peut utiliser la cuisine même si nous ne l'avons pas fait."

![France](https://a.travel-assets.com/egds/marks/flags/fr.svg)

noemie

[](https://www.expedia.com/Boquete-Hotels-Autana-Bed-And-Breakfast-Hostel.h15982263.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-11&endDate=2026-03-12&regionId=142&adults=2&property_amenities_group_explore=smokefree_property&sort=RECOMMENDED&openPlayBack=true)

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## Top Panama Hotel Reviews

![The Executive Hotel](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/493046b7_y.jpg)

### The Executive Hotel

10/10 Excellent

"Everything was perfect"

[](https://expedia.com/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information)

![Sheraton Grand Panama](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/179e52b4_y.jpg)

### Sheraton Grand Panama

10/10 Excellent

"Overall enjoyable"

[](https://expedia.com/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information)

![W Panama](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1_y.jpg)

### W Panama

10/10 Excellent

"Great service "

[](https://expedia.com/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information)

![Las Americas Golden Tower Panama](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/83f7ceed_y.jpg)

### Las Americas Golden Tower Panama

10/10 Excellent

"No problems at check in, clean room. Plan on utilizing again when we come back "

[](https://expedia.com/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information)

![Hotel El Panama by Faranda Grand, a member of Radisson Individuals](https://images.trvl-media.com/lodging/1000000/10000/7200/7164/cfc3400a_y.jpg)

### Hotel El Panama by Faranda Grand, a member of Radisson Individuals

10/10 Excellent

"Yes nice and clean"

[](https://expedia.com/Panama-City-Hotels-Hotel-El-Panama-By-Faranda-Grand.h7164.Hotel-Information)

![Dreams Playa Bonita Panama - All Inclusive](https://images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/7c338453_y.jpg)

### Dreams Playa Bonita Panama - All Inclusive

10/10 Excellent

"Excellent service and amazing places.we have a great time ❤️😘love it!!!"

[](https://expedia.com/Panama-City-Hotels-Dreams-Playa-Bonita-Panama.h12445554.Hotel-Information)

![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg)

### Hotel Riu Plaza Panama

10/10 Excellent

"Amazing employees"

[](https://expedia.com/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information)

![JW Marriott Panama](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6_y.jpg)

### JW Marriott Panama

10/10 Excellent

"Great stay"

[](https://expedia.com/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information)

![Principe Hotel and Suites](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4_y.jpg)

### Principe Hotel and Suites

10/10 Excellent

"The staff was courteous and the hotel always was clean including my room."

[](https://expedia.com/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information)

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