Title: Panama Non-Smoking Hotels from $69 - Fully Refundable Options - Expedia.com

[Panama Travel Guide](https://expedia.com/Panama.dx142)[Panama Hotels](https://expedia.com/Destinations-In-Panama.d142.Hotel-Destinations)[Vacation Rentals in Panama](https://expedia.com/Destinations-In-Panama.d142.Vacation-Rental-Destinations)[Panama Flights](https://expedia.com/Destinations-In-Panama.d142.Flight-Destinations)[Car Rentals in Panama](https://expedia.com/Destinations-In-Panama.d142.Car-Rental-Destinations)[Panama Vacations](https://expedia.com/Panama.d142.Destination-Travel-Guides)

![Panama featuring landscape views, tropical scenes and island images](https://images.trvl-media.com/place/142/329febe6-4cd6-48f7-a9e8-71ea862bef81.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by PhotoJoy

![](https://images.trvl-media.com/place/142/329febe6-4cd6-48f7-a9e8-71ea862bef81.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Top Cities in Panama

![](https://mediaim.expedia.com/destination/1/1916fc53ea2cb142bbaeb7b9e6efaf16.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### Panama City

[](https://expedia.com/Panama-City-Hotels-Smoke-Free-Hotels.0-0-d2897-tSmokeFreeHotels.Travel-Guide-Filter-Hotels)

![](https://mediaim.expedia.com/destination/1/25f99a393b969b3735c64d4b492225c8.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### Bocas del Toro

[](https://expedia.com/Bocas-Del-Toro-Hotels-Smoke-Free-Hotels.0-0-d6023445-tSmokeFreeHotels.Travel-Guide-Filter-Hotels)

## Check availability on Panama Non-Smoking Hotels

Tonight

[Feb 19 - Feb 20](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-02-19&endDate=2026-02-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Feb 20 - Feb 21](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-02-20&endDate=2026-02-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Feb 20 - Feb 22](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-02-20&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Feb 27 - Mar 1](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-02-27&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Panama non-smoking hotels

![Beach nearby](https://images.trvl-media.com/lodging/19000000/18840000/18839300/18839207/0b87514e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/19000000/18840000/18839300/18839207/d62404a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/19000000/18840000/18839300/18839207/a6ff72a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/19000000/18840000/18839300/18839207/c7b3b49f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 1st Floor Beach House Apartment just steps from the beach!

[](https://www.expedia.com/Las-Tablas-Hotels-1st-Floor-Beach-House-Apartment-Just-Steps-From-The-Beach.h18839207.Hotel-Information)

Las Tablas

9.4/10

Exceptional

(6 reviews)

"Although my visit was short the property had everything needed for a wonderful stay. The property manager was extremely helpful."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Deborah I.

[](https://www.expedia.com/Las-Tablas-Hotels-1st-Floor-Beach-House-Apartment-Just-Steps-From-The-Beach.h18839207.Hotel-Information)

![Beach nearby](https://images.trvl-media.com/lodging/19000000/18840000/18839500/18839466/0e658cfc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/19000000/18840000/18839500/18839466/2a78506f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/19000000/18840000/18839500/18839466/e77096ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/19000000/18840000/18839500/18839466/ae2bd9ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 2 Story 3 Bed/2 Bath House with separate units just steps from the beach!!

[](https://www.expedia.com/Las-Tablas-Hotels-2-Story-Beach-House-Just-Steps-From-The-Beach.h18839466.Hotel-Information)

Las Tablas

9.6/10

Exceptional

(4 reviews)

"Nice beach access "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

jay

[](https://www.expedia.com/Las-Tablas-Hotels-2-Story-Beach-House-Just-Steps-From-The-Beach.h18839466.Hotel-Information)

![2 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/19000000/18840000/18839600/18839580/119b378b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, DVD player](https://images.trvl-media.com/lodging/19000000/18840000/18839600/18839580/f4008080.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/19000000/18840000/18839600/18839580/08653042.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/19000000/18840000/18839600/18839580/712bd3c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 2nd Floor Beach House Apartment just steps from the beach!

[](https://www.expedia.com/Las-Tablas-Hotels-2nd-Floor-Beach-House-Apartment-Just-Steps-From-The-Beach.h18839580.Hotel-Information)

Las Tablas

8.6/10

Excellent

(4 reviews)

"Fully furnished. Newly remodeled. Very quiet. Bring your own beach chairs. Good shelling at low tide! Enjoy!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Archie L.

[](https://www.expedia.com/Las-Tablas-Hotels-2nd-Floor-Beach-House-Apartment-Just-Steps-From-The-Beach.h18839580.Hotel-Information)

![Rooftop terrace](https://images.trvl-media.com/lodging/13000000/12890000/12880400/12880383/043c855c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/13000000/12890000/12880400/12880383/2e951e3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/13000000/12890000/12880400/12880383/d365d94c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lounge](https://images.trvl-media.com/lodging/13000000/12890000/12880400/12880383/d13c98d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### AC Hotel by Marriott Panama City

[](https://www.expedia.com/Panama-City-Hotels-AC-Hotel-By-Marriott-Panama-City.h12880383.Hotel-Information)

Bella Vista

8.8/10

Excellent

(773 reviews)

"The staff was exceptional and the room was great. Best stay in my life. 100% recommended"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Javanny

$112 nightly

$123 total

Mar 1 - Mar 2

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-AC-Hotel-By-Marriott-Panama-City.h12880383.Hotel-Information)

![Interior detail](https://images.trvl-media.com/lodging/2000000/1420000/1410100/1410051/194428d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Double Room, 2 Double Beds | Premium bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/2000000/1420000/1410100/1410051/8ab07dee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; American cuisine, garden views ](https://images.trvl-media.com/lodging/2000000/1420000/1410100/1410051/fa98dd9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Garden](https://images.trvl-media.com/lodging/2000000/1420000/1410100/1410051/995a9fa7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Albrook Inn

[](https://www.expedia.com/Panama-City-Hotels-Albrook-Inn.h1410051.Hotel-Information)

Panama City

7.8/10

Good

(579 reviews)

"Friendly front desk staff, comfortable bed, close proximity to airport"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Hildi

$63 nightly

$69 total

Feb 21 - Feb 22

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-Albrook-Inn.h1410051.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/7000000/6580000/6577500/6577427/75c7ddd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/7000000/6580000/6577500/6577427/590df444.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/7000000/6580000/6577500/6577427/8c2779b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/7000000/6580000/6577500/6577427/02a8cee5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aloft Panama

[](https://www.expedia.com/Panama-City-Hotels-Aloft-Panama.h6577427.Hotel-Information)

San Francisco

8.6/10

Excellent

(959 reviews)

"Perfect stay for a few days at Panama!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Maria

$119 nightly

$131 total

Feb 27 - Feb 28

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-Aloft-Panama.h6577427.Hotel-Information)

![Breakfast, lunch served; local and international cuisine, garden views ](https://images.trvl-media.com/lodging/7000000/6420000/6417200/6417143/c3192737.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/7000000/6420000/6417200/6417143/3caa6f92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property - evening/night](https://images.trvl-media.com/lodging/7000000/6420000/6417200/6417143/32c9362e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/7000000/6420000/6417200/6417143/af7444f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### American Trade Hotel

[](https://www.expedia.com/Panama-City-Hotels-American-Trade-Hotel.h6417143.Hotel-Information)

Casco Viejo

9.4/10

Exceptional

(659 reviews)

"Perfect location with attentive staff and nice rooms"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Negar

$225 nightly

$250 total

Feb 26 - Feb 27

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-American-Trade-Hotel.h6417143.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1860000/1855400/1855396/d94a299c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior entrance](https://images.trvl-media.com/lodging/2000000/1860000/1855400/1855396/65de3fea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cabin | Private kitchen](https://images.trvl-media.com/lodging/2000000/1860000/1855400/1855396/58f20ea0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1860000/1855400/1855396/50e6b100.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Anton Valley Hotel

[](https://www.expedia.com/El-Valle-De-Anton-Hotels-Anton-Valley-Hotel.h1855396.Hotel-Information)

El Valle de Anton

7.8/10

Good

(68 reviews)

"Very central with a restaurant and spa. Big room with kitchen"

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Donna

[](https://www.expedia.com/El-Valle-De-Anton-Hotels-Anton-Valley-Hotel.h1855396.Hotel-Information)

![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/10000000/9820000/9810500/9810426/001e44b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/10000000/9820000/9810500/9810426/9246a1c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/10000000/9820000/9810500/9810426/8e04e5d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/10000000/9820000/9810500/9810426/6fd41e9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aranjuez Hotel & Suites

[](https://www.expedia.com/David-Hotels-Aranjuez-Hotel-Suites.h9810426.Hotel-Information)

David Sur

9.2/10

Wonderful

(797 reviews)

"Wonderful staff & great restaurant"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

KAREN

$67 nightly

$75 total

Feb 27 - Feb 28

Total with taxes and fees

[](https://www.expedia.com/David-Hotels-Aranjuez-Hotel-Suites.h9810426.Hotel-Information)

![Dining](https://images.trvl-media.com/lodging/16000000/15990000/15982300/15982263/76f4e974.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/16000000/15990000/15982300/15982263/6c130679.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/16000000/15990000/15982300/15982263/c206981c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/16000000/15990000/15982300/15982263/b7d94b85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Autana Bed and Breakfast - Hostel

[](https://www.expedia.com/Boquete-Hotels-Autana-Bed-And-Breakfast-Hostel.h15982263.Hotel-Information)

Los Naranjos

7.2/10

Good

(5 reviews)

"Endroit calme un peu à l'écart de la ville et donc nécessitant d'avoir une voiture. L'endroit est une belle découverte. Certes, c'est un peu rustique mais la personne qui s'occupe de l'endroit est vraiment extrêmement gentil et serviable. C'est une belle surprise... rustique mais vraiment sympa. Autre point, on peut utiliser la cuisine même si nous ne l'avons pas fait."

![France](https://a.travel-assets.com/egds/marks/flags/fr.svg)

noemie

[](https://www.expedia.com/Boquete-Hotels-Autana-Bed-And-Breakfast-Hostel.h15982263.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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## Top Panama Hotel Reviews

![Waymore Hotel Spa & Casino](https://images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/75048cd3_y.jpg)

### Waymore Hotel Spa & Casino

10/10 Excellent

"Room was spotless and staff friendly and very courteous "

[](https://expedia.com/Panama-City-Hotels-Waymore-Hotel-Spa-Casino.h96825193.Hotel-Information)

![Sheraton Grand Panama](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/179e52b4_y.jpg)

### Sheraton Grand Panama

10/10 Excellent

"That was good"

[](https://expedia.com/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information)

![Marriott Panama Hotel](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540_y.jpg)

### Marriott Panama Hotel

10/10 Excellent

"Yes"

[](https://expedia.com/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information)

![Las Americas Golden Tower Panama](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/83f7ceed_y.jpg)

### Las Americas Golden Tower Panama

10/10 Excellent

"Tremendous views of the city from our 21st floor hotel room. Huge breakfast with large selection. The room was super comfortable and spacious. Loved the layout. The beds super comfortable The staff was excellent."

[](https://expedia.com/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information)

![The Executive Hotel](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/493046b7_y.jpg)

### The Executive Hotel

10/10 Excellent

"Room was clean and well appointed. We arrived early and the reception staff were great getting our luggage stored for the day. Very friendly team here and service was excellent. Included breakfast was awesome and it was great value for money. "

[](https://expedia.com/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information)

![The Westin Playa Bonita Panama](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/6d441b5e_y.jpg)

### The Westin Playa Bonita Panama

10/10 Excellent

"The room más immaculate "

[](https://expedia.com/Panama-City-Hotels-The-Westin-Playa-Bonita-Panama.h4668643.Hotel-Information)

![Hotel El Panama by Faranda Grand, a member of Radisson Individuals](https://images.trvl-media.com/lodging/1000000/10000/7200/7164/cfc3400a_y.jpg)

### Hotel El Panama by Faranda Grand, a member of Radisson Individuals

10/10 Excellent

"Good"

[](https://expedia.com/Panama-City-Hotels-Hotel-El-Panama-By-Faranda-Grand.h7164.Hotel-Information)

![W Panama](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1_y.jpg)

### W Panama

10/10 Excellent

"Yes, everything was great and amazing. I had a fantastic vacation with this stay"

[](https://expedia.com/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information)

![Principe Hotel and Suites](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4_y.jpg)

### Principe Hotel and Suites

10/10 Excellent

"Room had a few stains but all good, very clean."

[](https://expedia.com/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information)

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