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A city skyline with a prominent arch bridge and a lit bridge over a calm river reflecting city lights.

Find all hotels by Red Roof Inn in O'Fallon, MO from $67

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Check prices for these dates, December 12 – 13, 2026

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Our top choices for O'Fallon Red Roof Inn

1. Red Roof Inn St Louis - Westport/ Maryland Heights

A hotel lobby with a reception desk, a red chair, a large window, and a wall-mounted TV.

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Hotels recommended for families in O'Fallon

Sleep Inn & Suites O'Fallon MO - Technology Drive

A hotel dining area with multiple wooden tables and chairs, a flat-screen TV mounted on the wall, and a decorative wall with vertical patterns.

Holiday Inn Express St. Louis West - O'Fallon by IHG

A multi-story hotel with a mix of brick and siding exteriors, multiple windows, and a well-maintained lawn.

Comfort Inn & Suites St. Louis - O'Fallon

A hotel room with a large bed, a sofa, a desk, and two framed pictures on the wall.

Staybridge Suites O'Fallon Chesterfield by IHG

A hotel entrance with a stone facade, a wooden archway, and a paved walkway.

Hilton Garden Inn St. Louis/O'Fallon MO

A spacious lobby with a high ceiling, a central seating area with sofas and a coffee table, and a large window providing natural light.

Super 8 by Wyndham O'Fallon MO/St. Louis Area

A hotel room with a bed, two bedside lamps, a chair, a desk with a telephone, and a large cityscape poster on the wall.

Residence Inn by Marriott O'Fallon

A spacious lobby with a stone fireplace, seating area, and a bar with high stools.

Centrally located, spacious 4 bdrm, on quiet Ct

A modern kitchen with white cabinets, stainless steel appliances, and a wooden dining table.

Top O'Fallon Hotel Reviews

Holiday Inn Express & Suites St Peters by IHG

A spacious lobby with a high ceiling, a reception desk, seating areas, and a staircase leading to an upper level.

River Sirens Hotel

A modern kitchen with a stainless steel refrigerator, a black countertop, and two stools.

Drury Plaza Hotel St. Louis Chesterfield

A spacious lobby with a central round table, two sofas, and a chandelier.

Hyatt Place St. Louis/Chesterfield

A modern kitchen with a bar area, wooden cabinets, and pendant lighting.

Residence Inn by Marriott St. Louis Chesterfield

An outdoor patio with a built-in grill, seating area, and stone walls.

Drury Inn & Suites Southwest St. Louis

A modern hotel lobby with a high ceiling, a central seating area with sofas and a coffee table, and a flat-screen TV mounted on the wall.

Holiday Inn Express & Suites Wentzville St Louis West by IHG

A spacious lobby with a reception desk, seating area, and a conference room.

Country Inn & Suites by Radisson, St. Charles Historic District

A brick building with a sign reading "Country Inn & Suites."

Sleep Inn & Suites O'Fallon MO - Technology Drive

A hotel dining area with multiple wooden tables and chairs, a flat-screen TV mounted on the wall, and a decorative wall with vertical patterns.

Pear Tree Inn St. Louis Airport

A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

Drury Plaza Hotel St. Louis Creve Coeur

A hotel lobby with a hot tub, a pool, and outdoor seating.

The Wildwood Hotel

A hotel with a prominent tower, a fountain in the courtyard, and a well-maintained garden.

AC Hotel by Marriott St. Louis Chesterfield

A modern hotel with a prominent entrance, a landscaped courtyard, and a well-lit facade.

Bay Inn & Suites Troy

A hotel lobby with a reception desk, a blue sofa, and orange armchairs.

SpringHill Suites by Marriott St. Louis Chesterfield

An outdoor seating area with a table and chairs, a fire feature, and a brick wall.

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