Title: Visit Santa Cruz: 2026 Travel Guide for Santa Cruz, Santa Cruz | Expedia.com [Hotels in Santa Cruz](https://expedia.com/Santa-Cruz-Hotels.d6053940.Travel-Guide-Hotels)[Vacation Rentals in Santa Cruz](https://expedia.com/Santa-Cruz-Vacation-Rentals.d6053940.Travel-Guide-VacationRentals)[Flights to Santa Cruz](https://expedia.com/Cheap-Flights-To-Santa-Cruz.d6053940.Travel-Guide-Flights)[Things to do in Santa Cruz](https://expedia.com/Things-To-Do-In-Santa-Cruz.d6053940.Travel-Guide-Activities)[Car Rentals in Santa Cruz](https://expedia.com/Car-Rentals-In-Santa-Cruz.d6053940.Car-Rental-Guide)[Santa Cruz Vacation Packages](https://expedia.com/Santa-Cruz.d6053940.Destination-Travel-Guides) # Santa Cruz ## Travel Guide ![San Lorenzo Cathedral showing a garden](https://images.trvl-media.com/place/6098830/62a42b3d-1dbd-4a81-8566-cea655ebca33.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![San Lorenzo Cathedral showing a garden](https://images.trvl-media.com/place/6098830/62a42b3d-1dbd-4a81-8566-cea655ebca33.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Santa Cruz which includes a city](https://images.trvl-media.com/place/6053940/75ffd331-c4fa-4895-94e7-13da747334c7.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![San Lorenzo Cathedral which includes heritage architecture and heritage elements](https://images.trvl-media.com/place/6098830/0b09144b-3bd2-4292-8648-1903a9368baa.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Santa Cruz which includes a city](https://images.trvl-media.com/place/6053940/61fe045e-dc5a-4dde-a0c1-963d4b39646b.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Santa Cruz Where to stay Things to do Reviews #### Experience Bolivia as the locals see it in the country’s busiest city, where the museums, public squares and churches give you a glimpse into their everyday lives. Although Santa Cruz de la Sierra, more commonly known as Santa Cruz, is the most populous city in Bolivia, it is still relatively unknown by tourists. Sample an authentic Bolivian lifestyle in this busy city. Visit Santa Cruz’s churches and museums for an insight into the region’s history or simply soak up the atmosphere over a drink with the friendly locals. Explore a city that started out in a totally different location. Santa Cruz was founded in 1561, but had to move west after several decades of fending off attacks. Visit the historic heart of the city in [Plaza 24 de Septiembre](https://www.expedia.com/Plaza-24-De-Septiembre-Santa-Cruz.d6098828.Vacation-Attraction), which is more than 400 years old, to relax with the locals, who are known as “cruceños.” The most distinctive attraction in the city is [San Lorenzo Cathedral](https://www.expedia.com/San-Lorenzo-Cathedral-Santa-Cruz.d6098830.Vacation-Attraction), which is immediately recognizable for its red-brick frontage featuring two clock towers standing on either side of a pediment. The cathedral hosts the Museum of Sacred Art, with exhibits that display religious icons and Jesuit relics. Climb to the top of the clock tower for panoramic views of the city. Wander around the Parque Arenal, a green space in the middle of the city. The park has a boating lagoon and the Museo Etnofolklorico (Santa Cruz Ethnographic Museum). Other museums in the city include the Guarani Museum, which examines the culture of the indigenous Guarani people, and the National History Museum. Take children to the Zoological Gardens, where they can meet animals from around Bolivia. The zoo’s llamas and sloths are always popular with younger visitors. Fly into the busiest airport in Bolivia, Viru Viru International Airport. Flights arrive here from destinations in both Bolivia and cities in North and South America. Some operators even fly here from cities in Europe, such as Madrid. Santa Cruz de la Sierra is located in the lowlands of Bolivia in the east of the country, which means that rainfall is high during the summer months around January. Come during the high season, between May and October, for more dependable weather but higher prices. ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=DX_SPRING_PROMO_6053940) ### Where to stay in Santa Cruz ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Hamacas While Hamacas isn't home to many top sights, Santa Cruz Zoo and Las Brisas Shopping Center are some notable places to visit nearby. [](https://expedia.com/Santa-Cruz-Hamacas.dx553248635975875143) [See our Where To Stay guide](https://expedia.com/Santa-Cruz.dx6053940.Where-To-Stay?rfrr=TG.LP.Dest.Neighborhoods) - Santa Cruz Hotel Deals - Vacation Rentals in Santa Cruz ![Camino Real Hotel](https://images.trvl-media.com/lodging/1000000/450000/444500/444475/9d61826a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Camino Real Hotel Av. San Martín y 4to. Anillo Santa Cruz $122 nightly $122 total Apr 10 - Apr 11 Book a stay at this luxury hotel in Santa Cruz. Enjoy free breakfast, a full-service spa, and 2 bars/lounges. Popular attractions Ventura Mall and Centro Cultural ... 9/10 Wonderful! (420 reviews) Spotless, large and comfortable room was well maintained. Friendly and helpful staff. Delicious breakfast buffet. Location is near excellent shopping and dining options. Reviewed on Feb 5, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F10%2F2026&endDate=4%2F11%2F2026&selected=444475&PinnedHotelID=444475&HadPinnedHotel=true®ionId=6053940) ![Ibis Santa Cruz DE LA Sierra](https://images.trvl-media.com/lodging/88000000/87140000/87138700/87138613/03d4f9ed_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Ibis Santa Cruz DE LA Sierra AVENIDA CRISTOBAL DE MENDOZA Santa Cruz $55 nightly $55 total Mar 13 - Mar 14 Book a stay at this business-friendly hotel in Santa Cruz. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ... 9.6/10 Exceptional! (95 reviews) Good Reviewed on Mar 8, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F13%2F2026&endDate=3%2F14%2F2026&selected=87138613&PinnedHotelID=87138613&HadPinnedHotel=true®ionId=6053940) ![Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel](https://images.trvl-media.com/lodging/1000000/20000/18800/18758/ce43592e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel Ave. San Martin, #455 Santa Cruz Fully refundable $136 nightly $136 total Mar 29 - Mar 30 Book a stay at this spa hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ... 9/10 Wonderful! (364 reviews) Yes Reviewed on Mar 8, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F29%2F2026&endDate=3%2F30%2F2026&selected=18758&PinnedHotelID=18758&HadPinnedHotel=true®ionId=6053940) [See all 293 properties in Santa Cruz](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=3%2F13%2F2026&endDate=3%2F14%2F2026®ionId=6053940) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Premium Suites Deluxe Aparthotel Equipetrol](https://images.trvl-media.com/lodging/25000000/24410000/24404300/24404225/b86b5103_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Premium Suites Deluxe Aparthotel Equipetrol Calle Las Azucenas No. 127 Santa Cruz Santa Cruz Book a stay at this business-friendly aparthotel in Santa Cruz. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Patio Design LifeStyle ... 9/10 Wonderful! (86 reviews) Clean rooms, friendly people who work there. Parking always a plus Reviewed on Feb 19, 2026 [](https://expedia.com/Santa-Cruz-Hotels-Premium-Suites-Deluxe-Aparthotel-Equipetrol.h24404225.Hotel-Information) ![Apart Hotel Premium Suites Santa Cruz](https://images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/9a481119_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Apart Hotel Premium Suites Santa Cruz Calle Las Begonias Nro 45 Santa Cruz Book a stay at this business-friendly apartment in Santa Cruz. Enjoy free WiFi, free parking, and room service. Popular attractions Patio Design LifeStyle Center ... 8.6/10 Excellent! (100 reviews) Place is clean , safe area , walking distance to shops Reviewed on Mar 10, 2026 [](https://expedia.com/Santa-Cruz-Hotels-Apart-Hotel-Premium-Suites-Santa-Cruz.h5928237.Hotel-Information) ![Terranova Suites](https://images.trvl-media.com/lodging/11000000/10960000/10950300/10950250/7e27a563_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Terranova Suites 7º Anillo 400 mts al Oeste de Santa Cruz Santa Cruz Stay at this aparthotel in Santa Cruz. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Las Brisas Shopping Center and Centro Cultural ... 8/10 Very Good! (90 reviews) Easy to access Reviewed on Apr 14, 2025 [](https://expedia.com/Santa-Cruz-Hotels-Terranova-Suites.h10950250.Hotel-Information) [See all properties in Santa Cruz](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=6053940&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Santa Cruz hotel availability [Tonight ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6053940&startDate=2026-03-12&endDate=2026-03-13)[Mar 12 - Mar 13](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6053940&startDate=2026-03-12&endDate=2026-03-13) [Tomorrow night ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6053940&startDate=2026-03-13&endDate=2026-03-14)[Mar 13 - Mar 14](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6053940&startDate=2026-03-13&endDate=2026-03-14) [This weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6053940&startDate=3%2F13%2F2026&endDate=3%2F15%2F2026)[Mar 13 - Mar 15](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6053940&startDate=3%2F13%2F2026&endDate=3%2F15%2F2026) [Next weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6053940&startDate=3%2F20%2F2026&endDate=3%2F22%2F2026)[Mar 20 - Mar 22](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6053940&startDate=3%2F20%2F2026&endDate=3%2F22%2F2026) ### Popular places to visit ![Plaza 24 de Septiembre which includes heritage architecture and heritage elements as well as a large group of people](https://images.trvl-media.com/place/6098828/2cbd296e-1bf4-483c-835b-4827ab9257d1.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Plaza 24 de Septiembre 4.5/5(26 reviews) The heart of Santa Cruz lies in this public square, where locals relax and tourists sightsee in a welcoming, laid-back atmosphere. [](https://expedia.com/Plaza-24-De-Septiembre-Santa-Cruz.d6098828.Vacation-Attraction) ![San Lorenzo Cathedral which includes heritage elements, heritage architecture and a church or cathedral](https://images.trvl-media.com/place/6098830/07633da9-6b86-46e4-8a7c-5cc7962f1701.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### San Lorenzo Cathedral 4.5/5(15 reviews) One of the most iconic landmarks in Santa Cruz is the city’s mighty cathedral, which houses a museum displaying important artwork. [](https://expedia.com/San-Lorenzo-Cathedral-Santa-Cruz.d6098830.Vacation-Attraction) #### Ventura Mall 4.5/5(28 reviews) During your visit to Santa Cruz, you can find the perfect gifts to bring home at Ventura Mall. Make some time to visit the cathedral while you're in the area. [](https://expedia.com/Ventura-Mall-Santa-Cruz.d553248634697753452.Vacation-Attraction) #### Guembe Biocenter 4.5/5(8 reviews) Explore the great outdoors at Guembe Biocenter, a lovely green space in Colinas del Urubo. While in the area, you can find time to visit its shops. [](https://expedia.com/Guembe-Biocenter-Santa-Cruz.d553248621532465358.Vacation-Attraction) #### Ramon Tahuichi Aguilera Stadium 3/5(1 review) Catch an event at Ramon Tahuichi Aguilera Stadium during your trip to Santa Cruz. While in the area, you can find time to visit its shops. [](https://expedia.com/Ramon-Tahuichi-Aguilera-Stadium-Santa-Cruz.d6098832.Vacation-Attraction) #### Cine Center 4/5(9 reviews) You can get tickets for a performance at Cine Center during your trip to Santa Cruz. While in the area, you can find time to visit its shops. [](https://expedia.com/Cine-Center-Santa-Cruz.d6126769.Vacation-Attraction) ### Things to do ![Fuerte de Samaipata, Bolivia](https://mediaim.expedia.com/localexpert/47039842/7ecefdd0-a146-4d89-9aae-e8e8d23d9dce.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Samaipata Fort Tour: Ancient Ruins in 1 Full Day $315 per adult [](https://expedia.com/things-to-do/samaipata-fort-tour-ancient-ruins-in-1-full-day.a47039842.activity-details) ![The Che Guevara route is the most peculiar tourist destination in Bolivia.](https://mediaim.expedia.com/localexpert/47090379/4d80936c-4385-44e9-80b9-8e7660c32ae6.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### 4D/3N Expedition: Che Guevara Route - Disconnect from the World $799 per adult [](https://expedia.com/things-to-do/4d3n-expedition-che-guevara-route-disconnect-from-the-world.a47090379.activity-details) ![Trekking through the area of ​​​​the last armed struggle of Che Guevara.](https://mediaim.expedia.com/localexpert/47088323/cdf71877-c1dc-46c6-8af1-3b0ab483f139.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### 3D/2N Getaway on the Che Guevara Route Live the Adventure! $699 per adult [](https://expedia.com/things-to-do/3d2n-getaway-on-the-che-guevara-route-live-the-adventure.a47088323.activity-details) [See all activities in Santa Cruz](https://expedia.com/Things-To-Do-In-Santa-Cruz.d6053940.Travel-Guide-Activities) ## Reviews of Santa Cruz 4.2 Top Destination 5 - Excellent 19 4 - Good 23 3 - Okay 7 2 - Disappointing 0 1 - Terrible 1 ### 4/5 - Good Verified traveler Very nice people ### 5/5 - Excellent Verified traveler I have family and friends in Santa Cruz ### 3/5 - Okay Verified traveler Most modern city in Bolivia with all big city traffic. ### 5/5 - Excellent Verified traveler A nice stopover for a couple of days, or base to explore the surrounding area. The real highlight of the area is Amboro National Park, and deserves extra time to relax, hike and explore. Santa Cruz city seems quite prosperous. People are friendly ### 4/5 - Good Steven People are nice. Leisure, food, etc. Is economical. ### 1/5 - Terrible markleonard99@h Wrong Santa Cruz!! ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Vacation Rentals - [Historic Hotels in Santa Cruz ](https://www.expedia.com/Destinations-In-Santa-Cruz-Historic-Hotel.0-0-d6297178-tHistoricHotel.Hotel-Filter-Destinations) - [Resorts & Hotels with Spas in Santa Cruz ](https://www.expedia.com/Destinations-In-Santa-Cruz-Spa-Hotel.0-0-d6297178-tSpaHotel.Hotel-Filter-Destinations) - [Family Hotels in Santa Cruz ](https://www.expedia.com/Destinations-In-Santa-Cruz-Family-Hotel.0-0-d6297178-tFamilyHotel.Hotel-Filter-Destinations) - [Hotel Wedding Venues Hotels in Santa Cruz ](https://www.expedia.com/Destinations-In-Santa-Cruz-Wedding-Hotels.0-0-d6297178-tWeddingHotels.Hotel-Filter-Destinations) - [Casino Hotels in Santa Cruz ](https://www.expedia.com/Destinations-In-Santa-Cruz-Casino-Hotel.0-0-d6297178-tCasinoHotel.Hotel-Filter-Destinations) - [Santa Cruz Hotels ](https://www.expedia.com/Destinations-In-Santa-Cruz.d6297178.Hotel-Destinations) - 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[Flights from Buffalo (BUF) to Santa Cruz (SRZ) ](https://www.expedia.com/lp/flights/buf/srz/buffalo-to-santa-cruz) - [Flights from Lima (LIM) to Santa Cruz (SRZ) ](https://www.expedia.com/lp/flights/lim/srz/lima-to-santa-cruz) - [Flights from Ashland (AHM) to Santa Cruz (SRZ) ](https://www.expedia.com/lp/flights/ahm/srz/ashland-to-santa-cruz) - [Flights from Houston (IAH) to Santa Cruz (SRZ) ](https://www.expedia.com/lp/flights/iah/srz/houston-to-santa-cruz) - [Flights from New York (JFK) to Santa Cruz (SRZ) ](https://www.expedia.com/lp/flights/jfk/srz/new-york-to-santa-cruz) - [Flights from Charleston (CRW) to Santa Cruz (SRZ) ](https://www.expedia.com/lp/flights/crw/srz/charleston-to-santa-cruz) - [Flights from Corumba (CMG) to Santa Cruz (SRZ) ](https://www.expedia.com/lp/flights/cmg/srz/corumba-to-santa-cruz) - [Flights from Tampa (TPA) to Santa Cruz (SRZ) ](https://www.expedia.com/lp/flights/tpa/srz/tampa-to-santa-cruz) - [Flights from Cochabamba (CBB) to Santa Cruz (SRZ) ](https://www.expedia.com/lp/flights/cbb/srz/cochabamba-to-santa-cruz) - [Flights from Cedar Rapids (CID) to Santa Cruz (SRZ) ](https://www.expedia.com/lp/flights/cid/srz/cedar-rapids-to-santa-cruz) - [Flights from Detroit (DTW) to Santa Cruz (SRZ) ](https://www.expedia.com/lp/flights/dtw/srz/detroit-to-santa-cruz) - [Flights from Santiago (SCL) to Santa Cruz (SRZ) ](https://www.expedia.com/lp/flights/scl/srz/santiago-to-santa-cruz) - [Flights from Salt Lake City (SLC) to Santa Cruz (SRZ) ](https://www.expedia.com/lp/flights/slc/srz/salt-lake-city-to-santa-cruz) - [Flights from Myrtle Beach (MYR) to Santa Cruz (SRZ) ](https://www.expedia.com/lp/flights/myr/srz/myrtle-beach-to-santa-cruz) - [Flights from London (LHR) to Santa Cruz (SRZ) ](https://www.expedia.com/lp/flights/lhr/srz/london-to-santa-cruz) - [Flights from Sokoto (SKO) to Santa Cruz (SRZ) ](https://www.expedia.com/lp/flights/sko/srz/sokoto-to-santa-cruz) - [Flights from Hanoi (HAN) to Santa Cruz (SRZ) ](https://www.expedia.com/lp/flights/han/srz/hanoi-to-santa-cruz) - [Flights from Guayaramerin (GYA) to Santa Cruz (SRZ) ](https://www.expedia.com/lp/flights/gya/srz/guayaramerin-to-santa-cruz) - [Flights from Bogotá (BOG) to Santa Cruz (SRZ) ](https://www.expedia.com/lp/flights/bog/srz/bogota-to-santa-cruz) - [Flights from Toronto (YYZ) to Santa Cruz (SRZ) ](https://www.expedia.com/lp/flights/yyz/srz/toronto-to-santa-cruz) - [Visit Santa Cruz ](https://www.expedia.com/Santa-Cruz.dx6297178) - [Sacred Art Museum ](https://www.expedia.com/Sacred-Art-Museum-Santa-Cruz.d553248621563217782.Vacation-Attraction) - [San Lorenzo Cathedral ](https://www.expedia.com/San-Lorenzo-Cathedral-Santa-Cruz.d6098830.Vacation-Attraction) - [Franco Aleman Cultural Center ](https://www.expedia.com/Franco-Aleman-Cultural-Center-Santa-Cruz.d553248621532371069.Vacation-Attraction) - [Santa Cruz Vacations ](https://www.expedia.com/Santa-Cruz.d6297178.Destination-Travel-Guides) - [Plaza 24 de Septiembre ](https://www.expedia.com/Plaza-24-De-Septiembre-Santa-Cruz.d6098828.Vacation-Attraction) - [La Recova Artisan Walk ](https://www.expedia.com/La-Recova-Artisan-Walk-Santa-Cruz.d553248621532371683.Vacation-Attraction) - [Guarani Nandereko Nomai Art and Culture Center ](https://www.expedia.com/Guarani-Nandereko-Nomai-Art-And-Culture-Center-Santa-Cruz.d553248621532371685.Vacation-Attraction) - [Artecampo ](https://www.expedia.com/Artecampo-Santa-Cruz.d553248621532371681.Vacation-Attraction) - [Arenal Park ](https://www.expedia.com/Arenal-Park-Santa-Cruz.d553248621563217785.Vacation-Attraction) - [Ethno-Folkloric Museum ](https://www.expedia.com/Ethno-Folkloric-Museum-Santa-Cruz.d6098834.Vacation-Attraction) - [Ramon Tahuichi Aguilera Stadium ](https://www.expedia.com/Ramon-Tahuichi-Aguilera-Stadium-Santa-Cruz.d6098832.Vacation-Attraction) - [Cine Center ](https://www.expedia.com/Cine-Center-Santa-Cruz.d6126769.Vacation-Attraction) - [Santa Cruz Vacation Rentals ](https://www.expedia.com/Destinations-In-Santa-Cruz.d6297178.Vacation-Rental-Destinations) - Cities near Santa Cruz - Places of interest [Colinas del Urubo](https://expedia.com/Colinas-Del-Urubo.dx6349680) - [Plaza 24 de Septiembre ](https://expedia.com/Plaza-24-De-Septiembre-Santa-Cruz.d6098828.Vacation-Attraction) - [Ventura Mall ](https://expedia.com/Ventura-Mall-Santa-Cruz.d553248634697753452.Vacation-Attraction) - [Guembe Biocenter ](https://expedia.com/Guembe-Biocenter-Santa-Cruz.d553248621532465358.Vacation-Attraction) - [Ramon Tahuichi Aguilera Stadium ](https://expedia.com/Ramon-Tahuichi-Aguilera-Stadium-Santa-Cruz.d6098832.Vacation-Attraction) - [Cine Center ](https://expedia.com/Cine-Center-Santa-Cruz.d6126769.Vacation-Attraction) - [Santa Cruz Zoo ](https://expedia.com/Santa-Cruz-Zoo-Santa-Cruz.d6098836.Vacation-Attraction) - [San Lorenzo Cathedral ](https://expedia.com/San-Lorenzo-Cathedral-Santa-Cruz.d6098830.Vacation-Attraction) - [Lomas de Arena Regional Park ](https://expedia.com/Lomas-De-Arena-Regional-Park-Santa-Cruz.d553248621563217780.Vacation-Attraction) - [Blacutt Square ](https://expedia.com/Blacutt-Square-Santa-Cruz.d6126767.Vacation-Attraction) - [Municipal Botanical Garden of Santa Cruz ](https://expedia.com/Municipal-Botanical-Garden-Of-Santa-Cruz-Santa-Cruz.d553248635951339810.Vacation-Attraction) - [Catedral de Santa Cruz ](https://expedia.com/Catedral-De-Santa-Cruz-Santa-Cruz.d553248621532465359.Vacation-Attraction) - [La Recova Artisan Walk ](https://expedia.com/La-Recova-Artisan-Walk-Santa-Cruz.d553248621532371683.Vacation-Attraction) - [Artecampo ](https://expedia.com/Artecampo-Santa-Cruz.d553248621532371681.Vacation-Attraction) - [Guarani Nandereko Nomai Art and Culture Center ](https://expedia.com/Guarani-Nandereko-Nomai-Art-And-Culture-Center-Santa-Cruz.d553248621532371685.Vacation-Attraction) - [Sacred Art Museum ](https://expedia.com/Sacred-Art-Museum-Santa-Cruz.d553248621563217782.Vacation-Attraction) - [Ethno-folkloric Museum ](https://expedia.com/Ethno-Folkloric-Museum-Santa-Cruz.d6098834.Vacation-Attraction) - [Arenal Park ](https://expedia.com/Arenal-Park-Santa-Cruz.d553248621563217785.Vacation-Attraction) - [Las Brisas Shopping Center ](https://expedia.com/Las-Brisas-Shopping-Center-Santa-Cruz.d553248635949096660.Vacation-Attraction) - [Franco Aleman Cultural Center ](https://expedia.com/Franco-Aleman-Cultural-Center-Santa-Cruz.d553248621532371069.Vacation-Attraction) - [Patio Design LifeStyle Center ](https://expedia.com/Patio-Design-LifeStyle-Center-Santa-Cruz.d916427946376515584.Vacation-Attraction) - [Parque Ecológico ](https://expedia.com/Parque-Ecologico-Santa-Cruz.d916256542859411456.Vacation-Attraction) - [Univalle ](https://expedia.com/Univalle-Santa-Cruz.d904138417051369472.Vacation-Attraction)