Find 4 Star Hotels in Florida Keys from $302

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Our top choices for Florida Keys 4-star hotels

Reefhouse Resort & Marina

Reefhouse Resort & Marina
4.5 star property
Key Largo
9.4 out of 10, Exceptional, (1,393 reviews)
"Clean rooms, nice staff, great beach area."
United States
Brittany
$339 nightly
The price is $376
Apr 19 - Apr 20
Total with taxes and fees
Reefhouse Resort & Marina

Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
4.0 star property
Key Largo
8.6 out of 10, Excellent, (1,017 reviews)
"The resort was beautiful. We really enjoyed our time there."
United States
Jessica
$401 nightly
The price is $451
Apr 28 - Apr 29
Total with taxes and fees
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Amara Cay Resort

Amara Cay Resort
4.0 star property
Matecumbe
8.8 out of 10, Excellent, (1,263 reviews)
"Yes the pool was fabulous. The Ocean view was quite good for a room that was not ocean front."
United States
Joseph
$283 nightly
The price is $319
Apr 20 - Apr 21
Total with taxes and fees
Amara Cay Resort

Hawks Cay Resort

Hawks Cay Resort
4.0 star property
Marathon
8.0 out of 10, Very Good, (1,003 reviews)
"4.5 of 5 stars - very nice resort"
United States
Robert
$377 nightly
The price is $423
Apr 26 - Apr 27
Total with taxes and fees
Hawks Cay Resort

Islander Resort

Islander Resort
4.0 star property
Matecumbe
9.4 out of 10, Exceptional, (1,006 reviews)
"Wonderful stay. Staff, rooms, grounds, food were all excellent."
United States
Kim
$359 nightly
The price is $404
Apr 27 - Apr 28
Total with taxes and fees
Islander Resort

Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
4.5 star property
Rock Harbor
8.8 out of 10, Excellent, (1,005 reviews)
"Overall wonderful resort and great location. "
United States
Kristie Howle
$448 nightly
The price is $504
Apr 12 - Apr 13
Total with taxes and fees
Playa Largo Resort & Spa, Autograph Collection

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
4.0 star property
Islamorada
9.0 out of 10, Wonderful, (179 reviews)
"Very, very good architectural design and construction. And a well-maintained facility."
United States
roy steven
$407 nightly
The price is $457
Apr 22 - Apr 23
Total with taxes and fees
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

La Siesta Resort & Villas

La Siesta Resort & Villas
4.0 star property
Matecumbe
8.6 out of 10, Excellent, (1,003 reviews)
"We had a enjoyable stay here and would come back again if we were ever in the area. "
United States
angela
$268 nightly
The price is $302
Apr 14 - Apr 15
Total with taxes and fees
La Siesta Resort & Villas

Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort
4.0 star property
Marathon
8.8 out of 10, Excellent, (1,003 reviews)
"Amazing resort "
United States
Joy
$474 nightly
The price is $534
Apr 19 - Apr 20
Total with taxes and fees
Tranquility Bay Beachfront Hotel and Resort

Villas At Hawks Cay Resort

Villas At Hawks Cay Resort
4.0 star property
Marathon
8.2 out of 10, Very Good, (183 reviews)
"We had a great stay."
United States
Elise
Villas At Hawks Cay Resort

Grassy Flats Resort & Beach Club

Grassy Flats Resort & Beach Club
4.0 star property
Marathon
9.4 out of 10, Exceptional, (421 reviews)
"Yes the view was nice, the hotel staff was nice and the room was clean"
United States
DEBORAH LEE
$360 nightly
The price is $405
Apr 27 - Apr 28
Total with taxes and fees
Grassy Flats Resort & Beach Club

The Islands of Islamorada

The Islands of Islamorada
4.0 star property
Matecumbe
9.8 out of 10, Exceptional, (73 reviews)
"This place exceeded my expectations. Such a beautiful and quiet setting. Don't want to leave, but I will definitely be backa a beautiful "
United States
Beth
$748 nightly
The price is $842
Apr 13 - Apr 14
Total with taxes and fees
The Islands of Islamorada

The Reef at Marathon, Florida Keys

The Reef at Marathon, Florida Keys
4.0 star property
Marathon
9.2 out of 10, Wonderful, (15 reviews)
"Absolutely LOVED this place!! Affordable rates first of all, clean! Arrived late for check in and it was a quick smooth process, friendly staff. Definitely going back! "
United States
Angie
The Reef at Marathon, Florida Keys

Marlin Bay Resort & Marina

Marlin Bay Resort & Marina
4.0 star property
Marathon
10.0 out of 10, Exceptional, (2 reviews)
"Wonderful vacation!"
United States
Chardell
Marlin Bay Resort & Marina

Waterfront Luxury Villa

Waterfront Luxury Villa
4.0 star property
Marathon Shores
Waterfront Luxury Villa

The Caribbean Resort Coconut Palm North

The Caribbean Resort Coconut Palm North
4.0 star property
Matecumbe
The Caribbean Resort Coconut Palm North
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Florida Keys

Snorkel crystal-clear waters teeming with colorful fish, then feast on fresh-caught lobster at a laid-back waterfront shack. Drive the scenic Overseas Highway, stopping at Key West's Ernest Hemingway Home and Dry Tortugas National Park for island adventures.

Top Florida Keys Hotel Reviews

Find out more about Florida Keys

You'll see that you are in fine company with a visit to Florida Keys. Vacationers similar to you have made it one of our top most visited locals the past two years. However, "location, location, location" applies to more than just your vacation destination. When you want to make your next vacation extra special, it's all about where you start each new day.

Properties as Gorgeous as Florida Keys

Florida Keys saw thousands of tourists in 2016, and Expedia's comment section boast comments that highlight how fabulous these properties are. When you book a 4-star hotel you can breathe easy knowing that these properties aim to exceed your needs. You'll never have to search for to sustain your exercise routine, an energizing swim, or nice dinner during your stay, thanks to all that these hotels provide. They aim to make their facilities and grounds pleasing from the instant you step onto the property and with every step across their floors. Florida Keys has dozens of wonderful lodgings that make for the ideal holiday.

Rooms have been fashioned to keep you as comfortable as possible, with amenities like premium bedding, designer bathroom products, and in-room tea or coffee. So, sit back and decompress. Moreover, if you find that you're need of something else, you can trust the staff will do their best to ensure you continue to be pleased during your stay there. These accommodations are so lovely that you'll regret the day you have to return home.

Book a 4-Star Hotel in Florida Keys Today!

A trip to Florida Keys should be one that you'll recollect for years to come, and booking a 4-star hotel can help create memories that are fabulous. Book a 4-star hotel in Florida Keys soon, because several other people are too.

Frequently asked questions

What are the best 4-star hotels in Florida Keys?
If your Florida Keys adventure is in Key Largo, stay at Playa Largo Resort & Spa, Autograph Collection. With lots of amenities such as a firepit and a pillowtop mattress, it earns top marks from many Expedia travelers. Another sought-after option here is Bakers Cay Resort Key Largo, Curio Collection by Hilton. It's also rated 4 stars and features a steam room and a swimming pool.
How much does it cost to stay in a 4-star hotel in Florida Keys?
With Expedia's filter tool, scoring a terrific deal on a 4-star hotel in Florida Keys just got easier. Start by keying in your chosen travel dates and length of your stay. Then list the results by price and pick a property that best matches your style and budget.

  • Search for the lowest price from $339

What's the difference between 5-star and 4-star hotels in Florida Keys?
If you choose to stay at a 4-star hotel in Florida Keys, you'll typically find plenty of amenities to keep you relaxed, such as a restaurant, pool and gym. You can enjoy top-quality service and upmarket surroundings. Opt for a 5-star hotel and you'll have access to a few more perks — think concierge assistance, on-site spas and indulgent turndown services. You're likely to get more amenities and exclusive services at a 5-star getaway, but both are terrific options for luxury guests.