Title: The Best 5 Star Hotels in Mestre from $136 | Expedia.com [Mestre Travel Guide](https://expedia.com/Mestre.dx4952)[Hotels in Mestre](https://expedia.com/Mestre-Hotels.d4952.Travel-Guide-Hotels)[Vacation Rentals in Mestre](https://expedia.com/Mestre-Vacation-Rentals.d4952.Travel-Guide-VacationRentals)[Flights to Mestre](https://expedia.com/Cheap-Flights-To-Mestre.d4952.Travel-Guide-Flights)[Things to do in Mestre](https://expedia.com/Things-To-Do-In-Mestre.d4952.Travel-Guide-Activities)[Car Rentals in Mestre](https://expedia.com/Car-Rentals-In-Mestre.d4952.Car-Rental-Guide)[Mestre Vacation Packages](https://expedia.com/Mestre.d4952.Destination-Travel-Guides) ![Aerial view of Forte Marghera in Mestre Italy former Austrian fortification protecting Venice with water filled moat, artillery bastion, barracks](https://images.trvl-media.com/place/3000661740/a83a86a7-cba6-4aa9-b16a-464a88306f2c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/3000661740/a83a86a7-cba6-4aa9-b16a-464a88306f2c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Mestre 5 Star Hotels Tonight [Apr 7 - Apr 8](https://www.expedia.com/Hotel-Search?regionId=4952&startDate=2026-04-07&endDate=2026-04-08&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Apr 8 - Apr 9](https://www.expedia.com/Hotel-Search?regionId=4952&startDate=2026-04-08&endDate=2026-04-09&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=4952&startDate=2026-04-10&endDate=2026-04-12&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 17 - Apr 19](https://www.expedia.com/Hotel-Search?regionId=4952&startDate=2026-04-17&endDate=2026-04-19&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Mestre 5-star hotels ![3 restaurants, breakfast, lunch, dinner served; Italian cuisine](https://images.trvl-media.com/lodging/2000000/1590000/1583200/1583191/3906e85f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite | Living area | 40-inch LED TV with satellite channels, TV, toys](https://images.trvl-media.com/lodging/2000000/1590000/1583200/1583191/437518fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment rooms, sauna, hot tub, steam room, body treatments](https://images.trvl-media.com/lodging/2000000/1590000/1583200/1583191/ab9c1295.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1590000/1583200/1583191/w2835h1889x0y1-c089b1f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Molino Stucky Venice [](https://www.expedia.com/Venice-Hotels-Hilton-Molino-Stucky-Venice.h1583191.Hotel-Information) La Giudecca 8.8/10 Excellent (1,003 reviews) "Lovely property with a very upscale feel. Just a short ride over to San Marcos on their shuttle or ride the local water buses for more adventure 👍" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jill $300 nightly $342 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/Venice-Hotels-Hilton-Molino-Stucky-Venice.h1583191.Hotel-Information) ![2 bars/lounges, cocktail bar](https://images.trvl-media.com/lodging/1000000/10000/3700/3624/dd59d66c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/10000/3700/3624/ed3577a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Roof Garden Suite | 1 bedroom, Frette Italian sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/1000000/10000/3700/3624/9a48eacb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/3700/3624/090ab099.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The St. Regis Venice [](https://www.expedia.com/Venice-Hotels-The-St-Regis-Venice.h3624.Hotel-Information) Venice City Center 9.6/10 Exceptional (121 reviews) "The hotel is amazing, placed in the heart of Venice and every single person from the staff was incredible to me and my family." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nicolás $1,230 nightly $1,364 total Apr 28 - Apr 29 Total with taxes and fees [](https://www.expedia.com/Venice-Hotels-The-St-Regis-Venice.h3624.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/210000/201300/201235/2a7b0bd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/210000/201300/201235/499585a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/210000/201300/201235/a17c3415.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/210000/201300/201235/e0e40e82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### NH Collection Venezia Grand Hotel Dei Dogi [](https://www.expedia.com/Venice-Hotels-NH-Collection-Venezia-Grand-Hotel-Dei-Dogi.h201235.Hotel-Information) Cannaregio 9.0/10 Wonderful (493 reviews) "We had a wonderful time, and the receptionist gave us a fabulous restaurant recommendation close by. Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Francisco $374 nightly $423 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/Venice-Hotels-NH-Collection-Venezia-Grand-Hotel-Dei-Dogi.h201235.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/450000/445200/445128/c87a4de0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/450000/445200/445128/37bd28ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/450000/445200/445128/d92edb1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food and drink](https://images.trvl-media.com/lodging/1000000/450000/445200/445128/f0a42e13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baglioni Hotel Luna - The Leading Hotels of the World [](https://www.expedia.com/Venice-Hotels-Baglioni-Hotel-Luna-The-Leading-Hotels-Of-The-World.h445128.Hotel-Information) Venice City Center 9.4/10 Exceptional (1,001 reviews) "Beautiful hotel, wonderful location, lovely atmosphere. Truly memorable." ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Ian $754 nightly $841 total Apr 22 - Apr 23 Total with taxes and fees [](https://www.expedia.com/Venice-Hotels-Baglioni-Hotel-Luna-The-Leading-Hotels-Of-The-World.h445128.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/93000000/92020000/92013900/92013875/4cf86529.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Special Over the Grand Canal | Premium bedding, minibar, in-room safe, soundproofing](https://images.trvl-media.com/lodging/93000000/92020000/92013900/92013875/053dfc1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/93000000/92020000/92013900/92013875/3ad3eb1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/93000000/92020000/92013900/92013875/f30d6942.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Venice Venice Hotel [](https://www.expedia.com/Venice-Hotels-The-Venice-Venice-Hotel.h92013875.Hotel-Information) Venice City Center 9.8/10 Exceptional (107 reviews) "The staff was great!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric $842 nightly $938 total Apr 26 - Apr 27 Total with taxes and fees [](https://www.expedia.com/Venice-Hotels-The-Venice-Venice-Hotel.h92013875.Hotel-Information) ![Daily buffet breakfast (EUR 36 per person)](https://images.trvl-media.com/lodging/65000000/64670000/64665900/64665805/719475d8_edited_be99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, Canal View (Renaissance) | View from room](https://images.trvl-media.com/lodging/65000000/64670000/64665900/64665805/df57e8b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/65000000/64670000/64665900/64665805/e078e07d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/65000000/64670000/64665900/64665805/91ea3e91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Radisson Collection Hotel, Palazzo Nani Venice [](https://www.expedia.com/Venice-Hotels-Radisson-Collection-Palazzo-Nani.h64665805.Hotel-Information) Cannaregio 9.8/10 Exceptional (180 reviews) "Nice staff, nice room, location is ok." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Priscilla $492 nightly $553 total Apr 9 - Apr 10 Total with taxes and fees [](https://www.expedia.com/Venice-Hotels-Radisson-Collection-Palazzo-Nani.h64665805.Hotel-Information) ![Lounge](https://images.trvl-media.com/lodging/1000000/30000/27300/27226/a22a5078.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, 1 Bedroom | Frette Italian sheets, premium bedding, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/30000/27300/27226/8f782ea8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom | Pool](https://images.trvl-media.com/lodging/1000000/30000/27300/27226/1d6be914.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, 1 Bedroom | Frette Italian sheets, premium bedding, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/30000/27300/27226/55c0f55d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Gritti Palace, a Luxury Collection Hotel, Venice [](https://www.expedia.com/Venice-Hotels-The-Gritti-Palace.h27226.Hotel-Information) Venice City Center 9.4/10 Exceptional (241 reviews) "Excellent place " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Prabakar $2,172 nightly $2,401 total Apr 19 - Apr 20 Total with taxes and fees [](https://www.expedia.com/Venice-Hotels-The-Gritti-Palace.h27226.Hotel-Information) ![Staircase](https://images.trvl-media.com/lodging/2000000/1600000/1593300/1593284/1e825745.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Building design](https://images.trvl-media.com/lodging/2000000/1600000/1593300/1593284/854b47f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Building design](https://images.trvl-media.com/lodging/2000000/1600000/1593300/1593284/14c5f29d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/2000000/1600000/1593300/1593284/0fa00b29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ca' Sagredo [](https://www.expedia.com/Venice-Hotels-Ca-Sagredo.h1593284.Hotel-Information) Venice City Center 9.2/10 Wonderful (486 reviews) "Excellent " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nathaly $398 nightly $450 total Apr 13 - Apr 14 Total with taxes and fees [](https://www.expedia.com/Venice-Hotels-Ca-Sagredo.h1593284.Hotel-Information) ![Suite, City View (terrace) | Living area | 32-inch Smart TV with satellite channels](https://images.trvl-media.com/lodging/16000000/15130000/15124400/15124381/d9ccabd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; local cuisine, alfresco dining ](https://images.trvl-media.com/lodging/16000000/15130000/15124400/15124381/f1f44d9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/16000000/15130000/15124400/15124381/w4835h3305x0y0-251e16dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/16000000/15130000/15124400/15124381/45207740.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palazzo Venart Luxury Hotel [](https://www.expedia.com/Venice-Hotels-Palazzo-Venart-Luxury-Hotel.h15124381.Hotel-Information) Venice City Center 9.8/10 Exceptional (170 reviews) "Beautiful, elegant property, situated in a central but quiet neighborhood. Breakfasts were outstanding. Will return again for sure." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary $693 nightly $773 total Apr 23 - Apr 24 Total with taxes and fees [](https://www.expedia.com/Venice-Hotels-Palazzo-Venart-Luxury-Hotel.h15124381.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/77000000/76980000/76973400/76973344/818dbb2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, 1 King Bed, Pool Access, City View | City view](https://images.trvl-media.com/lodging/77000000/76980000/76973400/76973344/99823920.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Grand Master Suite | Premium bedding, Tempur-Pedic beds, free minibar items, in-room safe](https://images.trvl-media.com/lodging/77000000/76980000/76973400/76973344/dcb9e55c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/77000000/76980000/76973400/76973344/4a98c161.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Nolinski Venezia - Evok Collection [](https://www.expedia.com/Venice-Hotels-Nolinski-Venezia.h76973344.Hotel-Information) Venice City Center 9.8/10 Exceptional (110 reviews) "Beautiful hotel, great location, and amazing staff. This is my new favorite hotel in Venice! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dee $856 nightly $953 total Apr 15 - Apr 16 Total with taxes and fees [](https://www.expedia.com/Venice-Hotels-Nolinski-Venezia.h76973344.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2060000/2051500/2051446/3707a5e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2060000/2051500/2051446/257d57e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, Canal View (Grand) | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/3000000/2060000/2051500/2051446/w4287h2850x3y0-6a277d76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2060000/2051500/2051446/8a0ef0a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sina Centurion Palace [](https://www.expedia.com/Venice-Hotels-Sina-Centurion-Palace.h2051446.Hotel-Information) Dorsoduro 9.0/10 Wonderful (620 reviews) "Everything was wonderful....great staff..all with loads of personality....best stay i have ever had in multiple trips to Venice." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Garry $619 nightly $693 total Apr 27 - Apr 28 Total with taxes and fees [](https://www.expedia.com/Venice-Hotels-Sina-Centurion-Palace.h2051446.Hotel-Information) ![55-inch flat-screen TV with satellite channels, TV, Netflix](https://images.trvl-media.com/lodging/1000000/980000/971000/970957/4208a326.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (Rio Moise) | Premium bedding, down comforters, memory foam beds, free minibar items](https://images.trvl-media.com/lodging/1000000/980000/971000/970957/e8a75159.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/980000/971000/970957/3b511f85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/980000/971000/970957/1c50292f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Violino D’Oro Venezia [](https://www.expedia.com/Venice-Hotels-Violino-DOro-Venezia.h970957.Hotel-Information) Venice City Center 10/10 Exceptional (60 reviews) "Great hotel with excellent breakfast, bar, and dinner service " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) john $779 nightly $868 total Apr 19 - Apr 20 Total with taxes and fees [](https://www.expedia.com/Venice-Hotels-Violino-DOro-Venezia.h970957.Hotel-Information) ![Presidential Suite, Canal View | Premium bedding, minibar, in-room safe, soundproofing](https://images.trvl-media.com/lodging/21000000/20210000/20204900/20204896/53ae629f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/21000000/20210000/20204900/20204896/9c328f6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/21000000/20210000/20204900/20204896/c430443c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/21000000/20210000/20204900/20204896/5604508d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Nani Mocenigo Palace [](https://www.expedia.com/Venice-Hotels-Hotel-Nani-Mocenigo-Palace.h20204896.Hotel-Information) Dorsoduro 9.8/10 Exceptional (685 reviews) "Absolutely amazing.. literally never stayed at a hotel so perfect. Clean, everyone was so accommodating and genuine. Best place in Venice " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Guy $359 nightly $406 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/Venice-Hotels-Hotel-Nani-Mocenigo-Palace.h20204896.Hotel-Information) ![In-room dining](https://images.trvl-media.com/lodging/23000000/22840000/22836800/22836766/7efcda71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/23000000/22840000/22836800/22836766/2a4588c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/23000000/22840000/22836800/22836766/3df232ae_edited_a9ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite Supreme, Canal View | Living area | 60-inch Smart TV with satellite channels, TV](https://images.trvl-media.com/lodging/23000000/22840000/22836800/22836766/86a68dd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### CĂ  Bonfadini Historic Experience [](https://www.expedia.com/Venice-Hotels-Ca-Bonfadini-Historic-Experience.h22836766.Hotel-Information) Cannaregio 9.8/10 Exceptional (215 reviews) "Fantastic stay here. The staff were super friendly and attentive. Breakfast was decent with cooked to order options. The hotel is about 20mins walk to St Marc’s square. " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) James $525 nightly $589 total Apr 13 - Apr 14 Total with taxes and fees [](https://www.expedia.com/Venice-Hotels-Ca-Bonfadini-Historic-Experience.h22836766.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1710000/1703300/1703221/4c71c1a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Studio Suite, Canal View | Premium bedding, down comforters, minibar, in-room safe](https://images.trvl-media.com/lodging/2000000/1710000/1703300/1703221/9af6cbb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/2000000/1710000/1703300/1703221/db44ede8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Turkish bath](https://images.trvl-media.com/lodging/2000000/1710000/1703300/1703221/7795bc74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### EXCESS VENICE Boutique Hotel & Private Spa - Adults Only [](https://www.expedia.com/Venice-Hotels-EXCESS-VENICE-Boutique-Hotel-Private-Spa.h1703221.Hotel-Information) Dorsoduro 9.4/10 Exceptional (158 reviews) "Quiet neighbourhood. Easy access to attractions. Excellent service from staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jane Yu Yan $250 nightly $286 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/Venice-Hotels-EXCESS-VENICE-Boutique-Hotel-Private-Spa.h1703221.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/2000000/1500000/1498000/1497971/1c5f14c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Suite (Grand Canal) | View from room](https://images.trvl-media.com/lodging/2000000/1500000/1498000/1497971/2a43c3ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1500000/1498000/1497971/0741258c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1500000/1498000/1497971/c8003260.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palazzina Grassi [](https://www.expedia.com/Venice-Hotels-Palazzina-Grassi.h1497971.Hotel-Information) Venice City Center 9.2/10 Wonderful (226 reviews) "Such a lovely hotel the staff were exceptionally helpful and friendly making the stay even more special " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Paul $825 nightly $919 total Apr 9 - Apr 10 Total with taxes and fees [](https://www.expedia.com/Venice-Hotels-Palazzina-Grassi.h1497971.Hotel-Information) ![Suite, 1 Double Bed (Orient Express) | Minibar, in-room safe, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/121000000/120360000/120351200/120351127/b025bff8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Double Bed (Orient Express) | Minibar, in-room safe, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/121000000/120360000/120351200/120351127/0b2de175.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Double Bed (La Minerva) | Minibar, in-room safe, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/121000000/120360000/120351200/120351127/224117da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/121000000/120360000/120351200/120351127/84eb7dd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Orient Express Venezia [](https://www.expedia.com/Venice-Hotels-Orient-Express-Palazzo-Dona-Giovannelli.h120351127.Hotel-Information) Cannaregio $1,077 nightly $1,196 total Apr 16 - Apr 17 Total with taxes and fees [](https://www.expedia.com/Venice-Hotels-Orient-Express-Palazzo-Dona-Giovannelli.h120351127.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/92000000/91550000/91542200/91542192/5330e15c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/92000000/91550000/91542200/91542192/b2ddfbd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Double Room | Down comforters, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/92000000/91550000/91542200/91542192/293130a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, Canal View | Down comforters, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/92000000/91550000/91542200/91542192/07ab6aee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Eight Venezia [](https://www.expedia.com/Venice-Hotels-Palazzo-Maria-Formosa.h91542192.Hotel-Information) Castello 9.8/10 Exceptional (60 reviews) "Beautiful hotel and staff amazing. Loved our stay " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Simon John [](https://www.expedia.com/Venice-Hotels-Palazzo-Maria-Formosa.h91542192.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/3000000/2940000/2938800/2938724/8e513457.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/3000000/2940000/2938800/2938724/7531f23c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/3000000/2940000/2938800/2938724/f2a600f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room](https://images.trvl-media.com/lodging/3000000/2940000/2938800/2938724/1bf4d29d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bauer Casa Nova [](https://www.expedia.com/Venice-Hotels-Bauer-Casa-Nova.h2938724.Hotel-Information) Venice City Center [](https://www.expedia.com/Venice-Hotels-Bauer-Casa-Nova.h2938724.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Mestre-Hotels.s50-0-d4952.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Mestre-Hotels.s50-0-d4952.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Mestre. ![Amadeus Hotel](https://images.trvl-media.com/lodging/1000000/10000/7400/7339/ef042085_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Amadeus Hotel Lista di Spagna Venice VE $123 nightly $145 total Apr 19 - Apr 20 Total with taxes and fees 8/10 Very Good! (1,002 reviews) [](https://expedia.com/Venice-Hotels-Amadeus-Hotel.h7339.Hotel-Information) ![Hotel Principe](https://images.trvl-media.com/lodging/1000000/20000/11400/11393/f4fecbd5_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Principe Rio Tera Lista de Spagna, 146 Venice VE $115 nightly $136 total Apr 22 - Apr 23 Total with taxes and fees 8.8/10 Excellent! (1,003 reviews) [](https://expedia.com/Venice-Hotels-Hotel-Principe.h11393.Hotel-Information) ![Hotel Cavalletto e Doge Orseolo](https://images.trvl-media.com/lodging/1000000/10000/3600/3575/afde8200_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Cavalletto e Doge Orseolo Piazza San Marco 1107 Venice VE $198 nightly $228 total Apr 12 - Apr 13 Total with taxes and fees 8.8/10 Excellent! (1,731 reviews) [](https://expedia.com/Venice-Hotels-Hotel-Cavalletto-E-Doge-Orseolo.h3575.Hotel-Information) Still don't see what you're looking for? [See all properties in Mestre.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=4%2F8%2F2026&endDate=4%2F9%2F2026®ionId=4952&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=4%2F8%2F2026&endDate=4%2F9%2F2026®ionId=4952&star=50&star=50&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=4%2F8%2F2026&endDate=4%2F9%2F2026®ionId=4952&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=4%2F8%2F2026&endDate=4%2F9%2F2026®ionId=4952&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=4%2F8%2F2026&endDate=4%2F9%2F2026®ionId=4952&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=4%2F8%2F2026&endDate=4%2F9%2F2026®ionId=4952&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Mestre While often overlooked as Venice's mainland gateway, Mestre offers its own treasures with the striking Torre Civica and vibrant Piazza Ferretto at its heart. Catch performances at Teatro Toniolo or rent bikes to explore Parco San Giuliano's green spaces with spectacular views across the lagoon. [See all hotels in Mestre](https://www.expedia.com/Hotel-Search?startDate=2026-04-21&endDate=2026-04-22&adults=2®ionId=4952) ![Aerial view of Forte Marghera in Mestre Italy former Austrian fortification protecting Venice with water filled moat, artillery bastion, barracks](https://images.trvl-media.com/place/3000661740/a83a86a7-cba6-4aa9-b16a-464a88306f2c.jpg?impolicy=fcrop&w=900&h=362&p=1&q=high) ## Top Mestre Hotel Reviews ## Find out more about Mestre You enjoy the finer things in life, both at home and on vacation. Why not demand total luxury on your trip to Mestre? There's no reason to delay a getaway to Mestre any longer. You'll join the multitudes of vacationers who have made Mestre so fashionable recently. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. What are you waiting for? Book one of Expedia's luxurious 5-star hotels in Mestre and get ready to be pampered like never before. ### 5-Star Hotels in Mestre You'll have a fantastic time at one of these 5-star hotels. Highly-rated eateries, top-notch customer care, and fabulous spa offerings are waiting for you. We've got 79 hotels in Mestre, some of which will have exactly what you desire. You can also look forward to an outstanding experience and fantastic customer care, so get ready for a wonderful adventure. How do you want to relax? 24-hour room service, so you can order that filet mignon in the wee hours of the morning? A mud wrap treatment that will leave you feeling refreshed and alive? Butler services? No matter what you want on a perfect getaway, you're bound to find it here. Don't want to take our word for it? Explore our listings and pick the perfect accommodation for your needs. You won't sleep and order room service the entire time, though. You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. Whatever you plan to do, the 5-star hotels in Mestre are the perfect place to relax after a busy day. ### Make Your Escape Numerous visitors make Mestre the place to vacation. Why not join their ranks? If you've been dreaming about a vacation set here, then go ahead and book it. A surge in interest means these great hotel rooms will go quickly. It's time to indulge yourself. Select one of our Mestre 5-star hotels today and settle down in complete comfort tomorrow. ## Frequently asked questions ### What are the best 5-star hotels in Mestre? ### How much does it cost to stay in a 5-star hotel in Mestre? > - Search for the lowest price per night from $136 ### What makes a hotel 5 stars in Mestre? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Hotels near Ferretto Square ](https://www.expedia.com/Ferretto-Square-Hotels.0-l6163963-0.Travel-Guide-Filter-Hotels) - [Hotels near Municipal Tower of Mestre ](https://www.expedia.com/Municipal-Tower-Of-Mestre-Hotels.0-l6224447-0.Travel-Guide-Filter-Hotels) - [Hotels near Toniolo Theatre ](https://www.expedia.com/Toniolo-Theatre-Hotels.0-l6222778-0.Travel-Guide-Filter-Hotels) - [Hotels near Mestre City Center ](https://www.expedia.com/Mestre-City-Center-Venice-Hotels.0-n3000661743-0.Travel-Guide-Filter-Hotels) - [Casino Hotels in Mestre City Center ](https://www.expedia.com/Mestre-City-Center-Venice-Hotels-Casino-Hotel.0-n3000661743-0-tCasinoHotel.Travel-Guide-Filter-Hotels) - 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