A street with a flower shop, a building with a sign reading "Teatro Tonino", and a red building in the background.

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Tonight
Sep 10 - Sep 11
Tomorrow
Sep 11 - Sep 12
This weekend
Sep 11 - Sep 13
Next weekend
Sep 18 - Sep 20

Our top choices for Mestre 5-star hotels

A waterfront dining area with outdoor seating, a brick building in the background, and a lamp post.
A swimming pool with a church spire in the background, surrounded by a railing and benches.
A spa area with a hot tub, candles, and a table with snacks and glasses.
A historic building with a prominent clock tower and the name "C. Stucky" on the facade. It features multiple windows and a central entrance with outdoor seating.

1. Hilton Molino Stucky Venice

Hilton Molino Stucky Venice
La Giudecca
United States
Josephine
$414 nightly
$467 total
Oct 4 - Oct 5
Total with taxes and fees
Hilton Molino Stucky Venice
A terrace with outdoor seating, a railing, and potted plants.
A luxurious lobby with a central bar, ornate chandeliers, and a patterned floor.
A terrace with a long dining table set for a meal, overlooking a canal with boats and historic buildings.
A luxurious bar area with marble flooring, a central bar counter, and multiple seating options.

2. Baglioni Hotel Luna - The Leading Hotels of the World

Baglioni Hotel Luna - The Leading Hotels of the World
Venice City Center
United States
Christina
$1,181 nightly
$1,311 total
Oct 6 - Oct 7
Total with taxes and fees
Baglioni Hotel Luna - The Leading Hotels of the World
A terrace with wicker furniture and a view of a historic building across a river.
A row of historic buildings with balconies, a canal, and gondolas.
A bar area with a view of a canal and gondola, a sofa, and a table with drinks.
A room with a round wooden table, two chairs, a vase with flowers, and a view of a large building with a dome.

3. The St. Regis Venice

The St. Regis Venice
Venice City Center
United Kingdom
Sibel Kiazim
$1,857 nightly
$2,054 total
Sep 27 - Sep 28
Total with taxes and fees
The St. Regis Venice
A luxurious bedroom with a large bed, ornate gold furniture, and a decorative ceiling.
A dining area with a round table set for two, a sofa, a chandelier, and a painting on the wall.

4. Cà Bonfadini Historic Experience

Cà Bonfadini Historic Experience
Cannaregio
United States
Michael
$625 nightly
$699 total
Sep 13 - Sep 14
Total with taxes and fees
Cà Bonfadini Historic Experience
A breakfast buffet with various food items and a decorative ceiling with circular lights.
A luxurious room with a grand chandelier, elegant furniture, and a large circular ceiling artwork.
A courtyard with a black gondola sculpture, outdoor seating, and a statue.
A canal with boats docked, a white building with classical architecture, and a yellow building with a red awning.

5. Radisson Collection Hotel, Palazzo Nani Venice

Radisson Collection Hotel, Palazzo Nani Venice
Cannaregio
Canada
Zheng
$676 nightly
$755 total
Sep 13 - Sep 14
Total with taxes and fees
Radisson Collection Hotel, Palazzo Nani Venice
A room with a bed, a wooden dresser, a desk with a chair, and a large mirror on the wall.
A courtyard with outdoor seating, a fountain, and a brick building with large windows.
A grand hallway with marble columns, a large ornate ceiling, and a dining area with a chandelier.
A wooden boat on a canal, a building with a green door, and people standing by the canal.

6. Hotel Nani Mocenigo Palace

Hotel Nani Mocenigo Palace
Dorsoduro
United States
Natalie
$519 nightly
$583 total
Sep 30 - Oct 1
Total with taxes and fees
Hotel Nani Mocenigo Palace
A terrace with two white cushioned chairs, a glass table with a vase of flowers, and a view of historic buildings including a tall tower.
A grand entrance with a red carpet leading to a door labeled "NOLENSKI."
A library with bookshelves, a piano, and a bar area.
An outdoor dining area with tables set for a meal, surrounded by white walls and large windows.

7. Nolinski Venezia - Evok Collection

Nolinski Venezia - Evok Collection
Venice City Center
United States
Bradley
$1,001 nightly
$1,113 total
Sep 13 - Sep 14
Total with taxes and fees
Nolinski Venezia - Evok Collection
A terrace with tables and chairs, a view of a historic building with a dome, and a body of water in the background.
A historic building with a large dome and adjacent smaller structures, a canal with boats, and a clear sky.
A waterfront restaurant with outdoor seating overlooking a canal, a gondola, and historic buildings in the background.
A rooftop pool area with lounge chairs and a view of a historic building in the background.

8. The Gritti Palace, a Luxury Collection Hotel, Venice

The Gritti Palace, a Luxury Collection Hotel, Venice
Venice City Center
United States
Rita
$2,751 nightly
$3,037 total
Oct 3 - Oct 4
Total with taxes and fees
The Gritti Palace, a Luxury Collection Hotel, Venice
A canal with gondolas, buildings with balconies, and a sign reading "VIOLINO D'ORO".
A hotel room with a large bed, striped curtains, and two bedside lamps.
A dining area with a table set for four, overlooking a street with buildings and greenery.
A well-furnished living room with a sofa, a glass coffee table, a bookshelf, and a mirror reflecting the room.

9. Violino D’Oro Venezia

Violino D’Oro Venezia
Venice City Center
Canada
Brent
$917 nightly
$1,021 total
Oct 5 - Oct 6
Total with taxes and fees
Violino D’Oro Venezia
A luxurious lobby with a grand chandelier, plush seating, a grand piano, and a large floral mural.
A canal with boats, buildings, and a bridge.
A grand lobby with a staircase, a chandelier, a green sofa, and a coffee table.
A table with a glass of cocktail garnished with mint and berries, and a plate of appetizers.

10. NH Collection Venezia Grand Hotel Dei Dogi

NH Collection Venezia Grand Hotel Dei Dogi
Cannaregio
United States
Mehmood
$565 nightly
$633 total
Sep 13 - Sep 14
Total with taxes and fees
NH Collection Venezia Grand Hotel Dei Dogi
A waterfront restaurant with tables set for dining, overlooking a canal with boats.
A dimly lit restaurant with tables set for dining, featuring a view of a historic building through a glass wall.
A room with a view of a canal, a bench, and a book on the windowsill.
A canal with boats and buildings along the water.

11. The Venice Venice Hotel

The Venice Venice Hotel
Cannaregio
United States
Matthew
$1,015 nightly
$1,128 total
Sep 16 - Sep 17
Total with taxes and fees
The Venice Venice Hotel
A room with a teal sofa, a wooden coffee table, a painting on the wall, and a bed with a black headboard.
A well-lit pathway leading to a building with a symmetrical facade, arched windows, and a central entrance.
A garden pathway leading to a body of water with buildings in the background.
A grand staircase with a red sofa, a marble table with flowers, and a large arched window.

12. Palazzo Venart Luxury Hotel

Palazzo Venart Luxury Hotel
Venice City Center
United States
AMEL
$850 nightly
$946 total
Oct 11 - Oct 12
Total with taxes and fees
Palazzo Venart Luxury Hotel
A grand staircase with ornate balustrades, leading to a door with a golden frame.
A balcony with a table set for two, overlooking a canal with buildings and a bridge.
A canal with gondolas, historic buildings, and a clear sky.
A grand lobby with a chandelier, ornate furniture, and a large floral arrangement.

13. Ca' Sagredo

Ca' Sagredo
Cannaregio
United States
Cassia
$688 nightly
$769 total
Oct 4 - Oct 5
Total with taxes and fees
Ca' Sagredo
A canal with buildings on either side, a bridge in the background, and a row of shops with awnings.
A spa area with a hot tub, wooden paneling, and a wall-mounted watch.
A bar area with a glass of wine, ice, and snacks.
A courtyard with a fountain, outdoor seating, and buildings in the background.

14. EXCESS VENICE Boutique Hotel & Private Spa - Adults Only

EXCESS VENICE Boutique Hotel & Private Spa - Adults Only
Dorsoduro
United States
Annie
$410 nightly
$462 total
Oct 8 - Oct 9
Total with taxes and fees
EXCESS VENICE Boutique Hotel & Private Spa - Adults Only
A modern hotel room with a red accent wall, a bed with white bedding, a red sofa, and a white coffee table.
A historic building with a dome, arched windows, and a canal with gondolas.
A formal dining table set with candles, flowers, and green apples.
A room with a sofa, a table with a plant, a fireplace, and a view of buildings outside.

15. Sina Centurion Palace

Sina Centurion Palace
Dorsoduro
United States
Joseph M
$828 nightly
$923 total
Sep 13 - Sep 14
Total with taxes and fees
Sina Centurion Palace
A grand hall with classical architecture, including columns and a high ceiling.
A luxurious room with a grand chandelier, elegant furniture, and ornate wall decorations.
A dining area with tables set for service, arched doorways, and a view of the outdoor patio.
A hotel room with a large bed, a sofa, a small table with a vase, and a large mirror.

16. Orient Express Venezia

Orient Express Venezia
Cannaregio
$1,978 nightly
$2,188 total
Sep 27 - Sep 28
Total with taxes and fees
Orient Express Venezia
An arched doorway leading to a canal with boats, historic buildings, and a rope barrier.
A courtyard with lounge chairs, a table, and potted plants.
A hotel room with a large bed, a view of a canal and buildings, and a table with chairs.
A bar area with a long counter, multiple chairs, and a patterned floor.

17. Palazzina Grassi

Palazzina Grassi
Venice City Center
United States
Alicia
$1,000 nightly
$1,111 total
Oct 9 - Oct 10
Total with taxes and fees
Palazzina Grassi
A bedroom with a large bed, wooden wardrobe, and a chandelier.
A courtyard with a wooden pathway, lush greenery, and white flowers.

18. Hotel Palazzo Giovanelli e Gran Canal

Hotel Palazzo Giovanelli e Gran Canal
Venice City Center
United Kingdom
john
$636 nightly
$710 total
Oct 6 - Oct 7
Total with taxes and fees
Hotel Palazzo Giovanelli e Gran Canal
A cozy seating area with plush sofas and ottomans, a round table with a bottle and glasses, and a wall adorned with green foliage.
A bathroom with a freestanding bathtub, a vanity with a mirror, and a window with curtains.
A hotel bathroom with a large mirror, a sink with a vanity, a toilet, and a window with curtains.
A room with a bed, a chair, a desk, and a wardrobe.

19. Eight Venezia

Eight Venezia
Castello
United Kingdom
Simon John
Eight Venezia
A room with a staircase, wooden furniture, a white sofa, and a painting.
A narrow street with a red building featuring a black arched door, two potted plants, and a red carpet leading to the entrance.
A dining area with wooden tables and chairs, a central bar, and chandeliers.
A bedroom with a sloped ceiling, a bed with patterned bedding, two red chairs, and two bedside lamps.

20. Bauer Casa Nova

Bauer Casa Nova
Venice City Center
Bauer Casa Nova
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Mestre.
Hotel Cavalletto e Doge Orseolo

Hotel Cavalletto e Doge Orseolo

Piazza San Marco 1107 Venice VE
$318 nightly
$360 total
Sep 27 - Sep 28
Total with taxes and fees
8.8/10 Excellent! (1,867 reviews)
Hotel Cavalletto e Doge Orseolo
Hotel Plaza Venice

Hotel Plaza Venice

Viale Stazione 36 Mestre VE
$162 nightly
$185 total
Sep 13 - Sep 14
Total with taxes and fees
8.8/10 Excellent! (1,023 reviews)
Hotel Plaza Venice
Amadeus Hotel

Amadeus Hotel

Lista di Spagna Venice VE
$177 nightly
$205 total
Sep 16 - Sep 17
Total with taxes and fees
8.2/10 Very Good! (1,009 reviews)
Amadeus Hotel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Mestre

While often overlooked as Venice's mainland gateway, Mestre offers its own treasures with the striking Torre Civica and vibrant Piazza Ferretto at its heart. Catch performances at Teatro Toniolo or rent bikes to explore Parco San Giuliano's green spaces with spectacular views across the lagoon.

See all hotels in Mestre
An aerial view of a city with a river meandering through it, surrounded by greenery and urban development.

Top Mestre Hotel Reviews

Find out more about Mestre

You enjoy the finer things in life, both at home and on vacation. Why not demand total luxury on your trip to Mestre? There's no reason to delay a getaway to Mestre any longer. You'll join the multitudes of vacationers who have made Mestre so fashionable recently. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. What are you waiting for? Book one of Expedia's luxurious 5-star hotels in Mestre and get ready to be pampered like never before.

5-Star Hotels in Mestre

You'll have a fantastic time at one of these 5-star hotels. Highly-rated eateries, top-notch customer care, and fabulous spa offerings are waiting for you. We've got 79 hotels in Mestre, some of which will have exactly what you desire. You can also look forward to an outstanding experience and fantastic customer care, so get ready for a wonderful adventure. How do you want to relax? 24-hour room service, so you can order that filet mignon in the wee hours of the morning? A mud wrap treatment that will leave you feeling refreshed and alive? Butler services? No matter what you want on a perfect getaway, you're bound to find it here. Don't want to take our word for it? Explore our listings and pick the perfect accommodation for your needs.

You won't sleep and order room service the entire time, though. You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. Whatever you plan to do, the 5-star hotels in Mestre are the perfect place to relax after a busy day.

Make Your Escape

Numerous visitors make Mestre the place to vacation. Why not join their ranks? If you've been dreaming about a vacation set here, then go ahead and book it. A surge in interest means these great hotel rooms will go quickly. It's time to indulge yourself. Select one of our Mestre 5-star hotels today and settle down in complete comfort tomorrow.

Frequently asked questions

What are the best 5-star hotels in Mestre?
Relais Ca Sabbioni, Cà Bonfadini Historic Experience and NH Collection Venezia Grand Hotel Dei Dogi are among the top 5-star hotels in Mestre, based on reviews by our customers. These upmarket hotels rate highly for things such as their location, conveniences and guest services. Choose your favorite and experience the best of everything.
How much does it cost to stay in a 5-star hotel in Mestre?
The amount you pay for a 5-star hotel in Mestre can vary based on the time of year you travel and how long you plan to stay, among a number of factors. Use our price per night filter and other search tools to land the best rate on a plush stay.
  • Search for the lowest price per night from $185
What makes a hotel 5 stars in Mestre?
From gourmet restaurants and 24-hour fitness centers to pools and the finest bedding, the 5-star experience in Mestre is all about indulgence and comfort. But it calls for more than just top-notch conveniences to get a 5-star rating. Accommodations also have to deliver outstanding guest services like in-room massages, laundry and dry cleaning and 24/7 room service.

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