Find 5 Star Hotels in Saint Helena Island, SC from $158
Most hotels are fully refundable. Because flexibility matters.
Save 10% or more on over 100,000 hotels worldwide as a One Key member.
Search over 2.9 million properties and 550 airlines worldwide.
Check availability on Saint Helena Island 5 Star Hotels
Compare Saint Helena Island 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.
511 Sunsuite
860 Sabal Ct
522 Sunsuite
104 Davis Love
622 New Haven
18 Veranda Beach Drive
694 Bonito Rd-sandy Palms
901 Gull Cove
728 Bonito Rd
863 Salt Cedar
708 Ocean Cottage Beach Home
625 Seahorse Annex
4 Periwinkle Ct
512 Sunsuites
132 Ocean Creek- Tee'd Up 14
708 Ocean Cottage
Explore similar 4-star hotels
194 Beach Club
Ready to experience the next standard in luxury? We know you're thinking about it. Indulge your every whim on your upcoming leisure time. There's no reason to delay a getaway to Saint Helena Island any longer. You'll join the multitudes of vacationers who have made Saint Helena Island so fashionable recently. Additionally, the hotels in this area receive high marks for customer service, so you know you'll be well cared for during your getaway. Don't wait any longer. Our 5-star hotels in Saint Helena Island are the perfect places to relax in during your next escape.
Book the Best Saint Helena Island 5-Star Hotels
Don't be afraid to live the high life while you're on vacation. Michelin-starred restaurants, concierges, and in-room massages are all at the ready. You're sure to find exactly the accommodation you need. Besides that, you'll find that these hotels are kept in great shape and provide a fine place to lay your head at night. How do you want to relax? A rejuvenating facial treatment to help your cares fall away? A concierge to help you make reservations at that outstanding restaurant? Plush carpeting, delectable chocolate desserts, and even space for your family pet in some cases...these hotels will leave you amazed.
Ready for experiences outside your hotel room? Don't worry. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. Whatever you plan to do, the 5-star hotels in Saint Helena Island are the perfect place to relax after an exciting day. Ready to learn more? Plenty of visitors recommend this location.
Your Getaway Starts Today
The results are in, and Saint Helena Island 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. Expedia can help you land a great deal on accommodation. It's time to plan your next great escape. Decide on one of our Saint Helena Island 5-star hotels today and decompress in complete comfort tomorrow.
Frequently asked questions
Saint Helena Island Hotels by Star Rating
Hotels in Saint Helena Island Neighborhoods
Stay near popular Saint Helena Island attractions
- Hunting Island Lighthouse
- Fort Fremont
- Penn Center
- Ocean Point Golf Course
- Ocean Creek Golf Club
- Chapel of Ease
- Red Piano Too Gallery
- York W. Bailey Museum
- Marine Corps Recruit Depot Parris Island
- Coligny Beach
- Palmetto Dunes Club
- Coligny Plaza
- Shelter Cove Harbour
- Harbour Town Golf Links
- Sea Pines Forest Preserve
- Harbour Town Lighthouse
- Edisto Beach State Park
- Palmetto Dunes Tennis & Pickleball Center
- Marine Corps Air Station Beaufort
- Atlantic Dunes by Davis Love III
More Hotel Options in Saint Helena Island
- Beach Hotels (1)
- Cheap Hotels (1)
- Family Hotels (1)
- Golf Hotels (1)
- Historic Hotels (1)
- Hotels & Resorts for Couples (1)
- Hotels with Air Conditioning (1)
- Hotels with Free Breakfast (1)
- Hotels with Free Parking (1)
- Hotels with Free Wifi (1)
- Hotels with Restaurants (1)
- Hotels with a Gym (1)
- Hotels with a View (1)
- Luxury Hotels (1)
- Non-Smoking Hotels (1)
More Accommodation Types in Saint Helena Island
- Vacation Homes in Saint Helena Island (568)
- Villas in Saint Helena Island (117)
- Condo Rentals in Saint Helena Island (104)
- Apartments in Saint Helena Island (44)
- Cottages in Saint Helena Island (9)
- Resorts in Saint Helena Island (3)
- Cabin Rentals in Saint Helena Island (1)
- Guest Houses in Saint Helena Island (1)
Explore more hotels
- Luxurious Ocean front, 3 bedroom, elevator, private pool, amenity cards avail.
- Your Time To Relax
- Charming 3b/2.5b Waterfront Bluff Villa 2015 on Dataw w/ Beach Pass & Bikes
- Direct Oceanfront, 65 inch Smart TV, Fireplace
- Oceanfront Villa with sunrise views. Watch dolphins from your private balcony!
- Condo w/ Pool Access - ½ Mi to Harbor Island Beach
- Fripp Island Elegance, Golf Cart incl., Quiet Tropical setting on the Water
- Serene St Helena Island Condo: Walk to Shore!
- Beautiful ocean views from every room. Very close to beach.
- **Golf and Wildlife views**, golf cart included, club cards available - 14 Fairway Club
- Tranquil Oceanfront Haven - Perfect for Family Getaways
- Tranquil Harbor Island Retreat - Steps to Pool & Beach
- Ocean View Cedar Reef Villa 2BR/2BA
- Ranch, 6 bedrooms and 5 baths home is beautifully furnished and fully equip.
- Oceanfront Resort Condo w/ Beach+Pool Access!
- Oceanfront Paradise!
- FRIPP ISLAND Limo golf cart, Bikes, Ping Pong, FirePit, Cards avail, sleeps 13
- 10-minute drive to the Beach, Pets Yes!
- Oceanside, steps to the Beach, pets considered, cards avail, Beach Club Complex
- Charming Dog Friendly Villa on Harbor Island steps from the boardwalk!