A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

Apartments in Defiance for Rent

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Check prices for these dates

In two weeks
Jul 31 - Aug 2
In two months
Sep 11 - Sep 13
In three months
Oct 9 - Oct 11
In four months
Nov 6 - Nov 8

Our top choices for Defiance apartments

Exterior

The Foundry Flat | Industrial-Inspired 2-Bedroom

The Foundry Flat | Industrial-Inspired 2-Bedroom
St. Charles Historic District
$291 nightly
The price is $320
Aug 2 - Aug 3
Total with taxes and fees
The Foundry Flat | Industrial-Inspired 2-Bedroom
A heated pool

Great for Business Travelers! Pool + Gym

Great for Business Travelers! Pool + Gym
O'Fallon
$155 nightly
The price is $179
Aug 9 - Aug 10
Total with taxes and fees
Great for Business Travelers! Pool + Gym
Property grounds

Chic 1- Queen Bed, Non Smoking-Near Airport, Kitchen, Twin Bed

Chic 1- Queen Bed, Non Smoking-Near Airport, Kitchen, Twin Bed
St. Louis
9.0 out of 10, Wonderful, (13 reviews)
"This was absolutely perfect and reasonable pricing I surely will be back "
United States
David G.
$91 nightly
The price is $97
Aug 9 - Aug 10
Total with taxes and fees
Chic 1- Queen Bed, Non Smoking-Near Airport, Kitchen, Twin Bed
1 bedroom, WiFi (free)

1 Queen Bed | Non-Smoking, Kitchen

1 Queen Bed | Non-Smoking, Kitchen
Westport
9.8 out of 10, Exceptional, (41 reviews)
"I really enjoy it here!"
United States
Anonymous traveler
$75 nightly
The price is $87
Jul 23 - Jul 24
Total with taxes and fees
1 Queen Bed | Non-Smoking, Kitchen
Exterior detail

2nd Street Loft - Riverview

2nd Street Loft - Riverview
Washington
10.0 out of 10, Exceptional, (11 reviews)
"This place was perfect for our weekend getaway! Beautifully decorated and clean! It is also right next to everything in historic downtown Washington, so that we could walk everywhere. "
United States
Tammy H.
$155 nightly
The price is $174
Jul 20 - Jul 21
Total with taxes and fees
2nd Street Loft - Riverview
Property grounds

The Driftwood Den | Boho-Inspired 2-Bedroom

The Driftwood Den | Boho-Inspired 2-Bedroom
St. Charles Historic District
10.0 out of 10, Exceptional, (3 reviews)
"Loved our stay here. Clean, comfortable, convenient. Couldn’t have been easier, in all aspects. Already plan to stay there again!!!"
United States
Kourtney S.
$274 nightly
The price is $302
Jul 20 - Jul 21
Total with taxes and fees
The Driftwood Den | Boho-Inspired 2-Bedroom
Interior

The Lofts of North Main Street

The Lofts of North Main Street
St. Charles Historic District
9.6 out of 10, Exceptional, (180 reviews)
"Great place to stay. Our go to when visiting St.Charles or STL"
United States
jeramy p.
$245 nightly
The price is $262
Jul 20 - Jul 21
Total with taxes and fees
The Lofts of North Main Street
1 bedroom, WiFi, bed sheets

Duplex Hideaway in St. Charles, MO

Duplex Hideaway in St. Charles, MO
St. Charles Historic District
9.8 out of 10, Exceptional, (7 reviews)
"I will stay here again. It was a great location for my visit. Lots of room and amenities. Highly recommend this location if you are visiting the St Louis area. Barely a mile to get to Hwy 70, so easy access to St Louis, St Peter's, Wentzville etc. Maybe two blocks from Historic St Charles and Ameristar Casino."
United States
Karen M.
$249 nightly
The price is $274
Jul 20 - Jul 21
Total with taxes and fees
Duplex Hideaway in St. Charles, MO
Fridge, microwave, stovetop, toaster

Charming Duplex on Main

Charming Duplex on Main
St. Charles Historic District
10.0 out of 10, Exceptional, (22 reviews)
"Great location"
United States
todd p.
$251 nightly
The price is $276
Jul 21 - Jul 22
Total with taxes and fees
Charming Duplex on Main
Exterior

Stay on Main Historic Studio

Stay on Main Historic Studio
St. Charles Historic District
9.2 out of 10, Wonderful, (36 reviews)
"Had a wonderful stay. It was a Monday night so parking was very easy and the room was clean and comfortable. I would recommend this place 100% "
United States
Sarah C.
$213 nightly
The price is $234
Aug 4 - Aug 5
Total with taxes and fees
Stay on Main Historic Studio
Interior

2 Bdr Upstairs Apt Walking Distance to Main St

2 Bdr Upstairs Apt Walking Distance to Main St
Saint Charles
8.0 out of 10, Very Good, (5 reviews)
"The best price-value ratio. Quiet neighborhood, close to the city center."
United States
Tamas P.
$289 nightly
The price is $318
Jul 20 - Jul 21
Total with taxes and fees
2 Bdr Upstairs Apt Walking Distance to Main St
TV

6th street 101 - Walk to Main St

6th street 101 - Walk to Main St
St. Charles Historic District
10.0 out of 10, Exceptional, (3 reviews)
"Excellent"
United States
Scott N.
$256 nightly
The price is $287
Jul 26 - Jul 27
Total with taxes and fees
6th street 101 - Walk to Main St
Smart TV

Prime Loft of Main Street

Prime Loft of Main Street
St. Charles Historic District
9.8 out of 10, Exceptional, (112 reviews)
"Host was great. The cutest place in the perfect spot! "
United States
Anonymous traveler
$261 nightly
The price is $279
Jul 20 - Jul 21
Total with taxes and fees
Prime Loft of Main Street
Interior

Amazing Renovated Historic Loft on Main Street

Amazing Renovated Historic Loft on Main Street
St. Charles Historic District
10.0 out of 10, Exceptional, (65 reviews)
"Lovely accommodations, very clean, well equipped, great location. "
United States
Emily B.
$260 nightly
The price is $278
Aug 3 - Aug 4
Total with taxes and fees
Amazing Renovated Historic Loft on Main Street
TV

Main Street Apartment

Main Street Apartment
St. Charles Historic District
9.6 out of 10, Exceptional, (39 reviews)
"Great location for shopping and a lot of restaurants nearby. Beds were very comfortable. "
United States
Brooke I.
$407 nightly
The price is $448
Jul 20 - Jul 21
Total with taxes and fees
Main Street Apartment
TV

1st Capitol Mansion - Suite 401

1st Capitol Mansion - Suite 401
St. Charles Historic District
7.4 out of 10, Good, (9 reviews)
"Nice property and a great location to all the shops and restaurants that St. Charles has to offer. The place was clean and nicely updated. Will definitely stay here again!"
United States
Emily L.
$225 nightly
The price is $253
Jul 26 - Jul 27
Total with taxes and fees
1st Capitol Mansion - Suite 401
Coffee/tea maker, fridge, microwave, oven

Historic Main St. Customs House Upstairs Apartment

Historic Main St. Customs House Upstairs Apartment
St. Charles Historic District
9.6 out of 10, Exceptional, (38 reviews)
"Lovely place to stay!"
United States
Margaret A.
$362 nightly
The price is $398
Jul 20 - Jul 21
Total with taxes and fees
Historic Main St. Customs House Upstairs Apartment
Interior

The Historic Bricks on Main

The Historic Bricks on Main
St. Charles Historic District
9.0 out of 10, Wonderful, (19 reviews)
"Great place, very fun. I’d stay again for sure. "
United States
Michael C.
$233 nightly
The price is $256
Jul 26 - Jul 27
Total with taxes and fees
The Historic Bricks on Main
Coffee/tea maker, fridge, microwave, oven

Quiet Neighborhood-Near Eats & Shops-Airport!

Quiet Neighborhood-Near Eats & Shops-Airport!
Brookside
10.0 out of 10, Exceptional, (2 reviews)
"This was an awesome place for 9 of us- plenty of rooms to sleep and bathrooms. The renter was very kind"
United States
Janet
$501 nightly
The price is $501
Jul 20 - Jul 21
Total with taxes and fees
Quiet Neighborhood-Near Eats & Shops-Airport!
TV

Walk to Main St | Pet-Friendly Apt

Walk to Main St | Pet-Friendly Apt
St. Charles Historic District
8.6 out of 10, Excellent, (16 reviews)
"Property was as advertised. Perfect for my needs, clean, quiet and convenient. Loved Historic St. Charles. Would recommend anytime! Thank you! "
United States
Brian B.
$296 nightly
The price is $326
Jul 20 - Jul 21
Total with taxes and fees
Walk to Main St | Pet-Friendly Apt
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Defiance Hotel Reviews

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

10/10 Excellent
"Everything was great, except for the cable TV."
Ugoma 1-night trip
Posted 1 hour ago
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Find out more about Defiance

Defiance Apartments information

Number of reviews
455
Accommodation
115 Apartments
Lowest Price
$87
Highest Price
$501

Frequently asked questions

What's it like to stay at an apartment in Defiance?
You can search through 10 apartments in Defiance for your stay. Make time to visit the region's favorite sights like Six Flags St. Louis.
Why choose an apartment versus a traditional hotel?
Often more spacious than a traditional hotel room, an apartment includes a kitchen for convenient home-cooked meals. Apartments are ideal for families who want the conveniences of home, and also for couples who want something in a quieter part of town.
What's a favorite apartment for a stay in Defiance?
Here are some of the top apartments in the area: The Lofts of North Main Street: Located in St. Charles, 19.2 mi/30.8 km from the heart of Defiance. Includes free WiFi, sofa beds, and Smart TVs. Access to onsite laundry facilities is available on site. 2 Queen Beds | Non-Smoking, Kitchen: Located 18.7 mi/30.1 km away in Maryland Heights. Free WiFi and Smart TVs are included. 1 Queen Bed | Non-Smoking, Kitchen: It's situated in Maryland Heights, 18.7 mi/30.1 km away. Includes free WiFi and Smart TVs. Prime Loft of Main Street: Located 19.2 mi/30.9 km away in St. Charles. Free WiFi, sofa beds, and Smart TVs are included. Access to onsite laundry facilities is available on site. Chic 1- Queen Bed, Non Smoking-Near Airport, Kitchen, Twin Bed: It's located in Overland, 20.7 mi/33.2 km from Defiance. Includes free WiFi, private balconies, and Smart TVs.
How many apartments will I be able to find in Defiance?
Expedia has 10 apartments to book in Defiance.
What can I expect from the weather during my trip to Defiance?
Weather is only one factor, but it can really affect your travel plans, especially if you're planning an extended stay in Defiance. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for Defiance is 48 inches.
What are the must-see places to visit in Defiance?
August A. Busch Memorial Conservation Area and Missouri River are a couple of scenic spots to enjoy the outdoors, whereas Historic Daniel Boone Home and Heritage Center is one of the cultural attractions. While here, Chandler Hill Vineyards and Sugar Creek Winery are other places worth a visit.
What's the best way to get to and around Defiance?
Knowing a bit about the transportation options can save you time when you get to your destination. Fly into St. Louis, MO (SUS-Spirit of St. Louis), which is located 7.5 mi (12 km) from the heart of the city. You can also search for flights into St. Louis Lambert Intl. Airport (STL), which is 23.5 mi (37.8 km) away. If you'd like to explore around the area, you may want a rental car for your journey.

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