A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

Apartments in Defiance for Rent

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Check prices for these dates

In two weeks
Aug 14 - Aug 16
In two months
Sep 25 - Sep 27
In three months
Oct 23 - Oct 25
In four months
Nov 20 - Nov 22

Our top choices for Defiance apartments

Exterior

The Foundry Flat | Industrial-Inspired 2-Bedroom

The Foundry Flat | Industrial-Inspired 2-Bedroom
St. Charles Historic District
$291 nightly
The price is $320
Aug 3 - Aug 4
Total with taxes and fees
The Foundry Flat | Industrial-Inspired 2-Bedroom
A heated pool

Great for Business Travelers! Pool + Gym

Great for Business Travelers! Pool + Gym
O'Fallon
$155 nightly
The price is $179
Aug 10 - Aug 11
Total with taxes and fees
Great for Business Travelers! Pool + Gym
Property grounds

Chic 1- Queen Bed, Non Smoking-Near Airport, Kitchen, Twin Bed

Chic 1- Queen Bed, Non Smoking-Near Airport, Kitchen, Twin Bed
St. Louis
9.0 out of 10, Wonderful, (13 reviews)
"This was absolutely perfect and reasonable pricing I surely will be back "
United States
David G.
$101 nightly
The price is $107
Aug 1 - Aug 2
Total with taxes and fees
Chic 1- Queen Bed, Non Smoking-Near Airport, Kitchen, Twin Bed
1 bedroom, WiFi, bed sheets

Duplex Hideaway in St. Charles, MO

Duplex Hideaway in St. Charles, MO
St. Charles Historic District
9.8 out of 10, Exceptional, (7 reviews)
"I will stay here again. It was a great location for my visit. Lots of room and amenities. Highly recommend this location if you are visiting the St Louis area. Barely a mile to get to Hwy 70, so easy access to St Louis, St Peter's, Wentzville etc. Maybe two blocks from Historic St Charles and Ameristar Casino."
United States
Karen M.
$243 nightly
The price is $267
Aug 2 - Aug 3
Total with taxes and fees
Duplex Hideaway in St. Charles, MO
Interior

2 Queen Beds | Non-Smoking, Kitchen

2 Queen Beds | Non-Smoking, Kitchen
Westport
9.8 out of 10, Exceptional, (38 reviews)
"Fantastic place!"
United States
Anonymous traveler
$96 nightly
The price is $111
Aug 4 - Aug 5
Total with taxes and fees
2 Queen Beds | Non-Smoking, Kitchen
Property grounds

The Driftwood Den | Boho-Inspired 2-Bedroom

The Driftwood Den | Boho-Inspired 2-Bedroom
St. Charles Historic District
10.0 out of 10, Exceptional, (3 reviews)
"Loved our stay here. Clean, comfortable, convenient. Couldn’t have been easier, in all aspects. Already plan to stay there again!!!"
United States
Kourtney S.
$272 nightly
The price is $300
Jul 30 - Jul 31
Total with taxes and fees
The Driftwood Den | Boho-Inspired 2-Bedroom
Interior

Amazing Renovated Historic Loft on Main Street

Amazing Renovated Historic Loft on Main Street
St. Charles Historic District
10.0 out of 10, Exceptional, (67 reviews)
"Lovely accommodations, very clean, well equipped, great location. "
United States
Emily B.
$243 nightly
The price is $260
Aug 3 - Aug 4
Total with taxes and fees
Amazing Renovated Historic Loft on Main Street
Interior

The Lofts of North Main Street

The Lofts of North Main Street
St. Charles Historic District
9.6 out of 10, Exceptional, (181 reviews)
"Great place to stay. Our go to when visiting St.Charles or STL"
United States
jeramy p.
$243 nightly
The price is $260
Aug 3 - Aug 4
Total with taxes and fees
The Lofts of North Main Street
Smart TV

Prime Loft of Main Street

Prime Loft of Main Street
St. Charles Historic District
9.8 out of 10, Exceptional, (114 reviews)
"Host was great. The cutest place in the perfect spot! "
United States
Anonymous traveler
$245 nightly
The price is $262
Aug 2 - Aug 3
Total with taxes and fees
Prime Loft of Main Street
Coffee/tea maker, fridge, microwave, oven

Historic Main St. Customs House Upstairs Apartment

Historic Main St. Customs House Upstairs Apartment
St. Charles Historic District
9.6 out of 10, Exceptional, (38 reviews)
"Lovely place to stay!"
United States
Margaret A.
$362 nightly
The price is $398
Aug 2 - Aug 3
Total with taxes and fees
Historic Main St. Customs House Upstairs Apartment
TV

Walk to Main St | Pet-Friendly Apt

Walk to Main St | Pet-Friendly Apt
St. Charles Historic District
8.6 out of 10, Excellent, (16 reviews)
"Property was as advertised. Perfect for my needs, clean, quiet and convenient. Loved Historic St. Charles. Would recommend anytime! Thank you! "
United States
Brian B.
$296 nightly
The price is $326
Aug 2 - Aug 3
Total with taxes and fees
Walk to Main St | Pet-Friendly Apt
Fridge, microwave, stovetop, toaster

Charming Duplex on Main

Charming Duplex on Main
St. Charles Historic District
10.0 out of 10, Exceptional, (23 reviews)
"Great location"
United States
todd p.
$243 nightly
The price is $267
Aug 2 - Aug 3
Total with taxes and fees
Charming Duplex on Main
Exterior

Stay on Main Historic Studio

Stay on Main Historic Studio
St. Charles Historic District
9.2 out of 10, Wonderful, (36 reviews)
"Had a wonderful stay. It was a Monday night so parking was very easy and the room was clean and comfortable. I would recommend this place 100% "
United States
Sarah C.
$213 nightly
The price is $234
Aug 2 - Aug 3
Total with taxes and fees
Stay on Main Historic Studio
TV

6th street 101 - Walk to Main St

6th street 101 - Walk to Main St
St. Charles Historic District
10.0 out of 10, Exceptional, (3 reviews)
"Excellent"
United States
Scott N.
$253 nightly
The price is $284
Aug 3 - Aug 4
Total with taxes and fees
6th street 101 - Walk to Main St
Dining

Great for Business Travelers! Studio Suite Near Edward Jones! Free Breakfast!

Great for Business Travelers! Studio Suite Near Edward Jones! Free Breakfast!
Westport
9.6 out of 10, Exceptional, (4 reviews)
"It was an easy experience renting this place"
United States
Dominic M.
$207 nightly
The price is $236
Aug 24 - Aug 25
Total with taxes and fees
Great for Business Travelers! Studio Suite Near Edward Jones! Free Breakfast!
TV

Main Street Apartment

Main Street Apartment
St. Charles Historic District
9.4 out of 10, Exceptional, (40 reviews)
"Great location for shopping and a lot of restaurants nearby. Beds were very comfortable. "
United States
Brooke I.
$407 nightly
The price is $448
Aug 2 - Aug 3
Total with taxes and fees
Main Street Apartment
Coffee/tea maker, fridge, microwave, oven

Quiet Neighborhood-Near Eats & Shops-Airport!

Quiet Neighborhood-Near Eats & Shops-Airport!
Brookside
10.0 out of 10, Exceptional, (2 reviews)
"This was an awesome place for 9 of us- plenty of rooms to sleep and bathrooms. The renter was very kind"
United States
Janet
$463 nightly
The price is $463
Aug 4 - Aug 5
Total with taxes and fees
Quiet Neighborhood-Near Eats & Shops-Airport!
Interior

2 Bdr Upstairs Apt Walking Distance to Main St

2 Bdr Upstairs Apt Walking Distance to Main St
Saint Charles
8.0 out of 10, Very Good, (5 reviews)
"The best price-value ratio. Quiet neighborhood, close to the city center."
United States
Tamas P.
$289 nightly
The price is $318
Aug 2 - Aug 3
Total with taxes and fees
2 Bdr Upstairs Apt Walking Distance to Main St
Interior

Family Home: Game Room & Huge Yard, Airport

Family Home: Game Room & Huge Yard, Airport
Maryland Heights
10.0 out of 10, Exceptional, (1 review)
"Very nice"
United States
Steven S.
$466 nightly
The price is $466
Aug 2 - Aug 3
Total with taxes and fees
Family Home: Game Room & Huge Yard, Airport
Interior

3BR Family+Game Retreat 8 min STL Airport/Westport

3BR Family+Game Retreat 8 min STL Airport/Westport
Maryland Heights
9.0 out of 10, Wonderful, (10 reviews)
"Great stay! We had everything we needed and the communication was perfect!"
United States
Melodie B.
$446 nightly
The price is $446
Aug 3 - Aug 4
Total with taxes and fees
3BR Family+Game Retreat 8 min STL Airport/Westport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Defiance Hotel Reviews

Best Western Plus St. Louis West-Westport

Best Western Plus St. Louis West-Westport

8/10 Good
"The lady at the front desk, I didn't get her name, was most friendly and helpful. And everyone was kind enough to hold our son's water bottle he left in our room until we could return for it."
Fredrick W 1-night trip
Posted 1 hour ago
Best Western Plus St. Louis West-Westport

Find out more about Defiance

Defiance Apartments information

Number of reviews
584
Accommodation
115 Apartments
Lowest Price
$107
Highest Price
$466

Frequently asked questions

What's it like to stay at an apartment in Defiance?
You'll find 10 apartments to choose from in Defiance for your stay.
Why choose an apartment versus a traditional hotel?
Often more spacious than a traditional hotel room, an apartment includes a kitchen for convenient home-cooked meals. Apartments are ideal for families who want the conveniences of home, and also for couples who want something in a quieter part of town.
What's a favorite apartment for a stay in Defiance?
Here are some of the top apartments in the area: The Lofts of North Main Street: Located in St. Charles, 19.2 mi/30.8 km from the heart of Defiance. Includes free WiFi, sofa beds, and Smart TVs. Access to onsite laundry facilities is available on site. 2 Queen Beds | Non-Smoking, Kitchen: Located 18.7 mi/30.1 km away in Maryland Heights. Free WiFi and Smart TVs are included. 1 Queen Bed | Non-Smoking, Kitchen: It's situated in Maryland Heights, 18.7 mi/30.1 km away. Includes free WiFi and Smart TVs. Prime Loft of Main Street: Located 19.2 mi/30.9 km away in St. Charles. Free WiFi, sofa beds, and Smart TVs are included. Access to onsite laundry facilities is available on site. Chic 1- Queen Bed, Non Smoking-Near Airport, Kitchen, Twin Bed: It's located in Overland, 20.7 mi/33.2 km from Defiance. Includes free WiFi, private balconies, and Smart TVs.
How many apartments will I be able to find in Defiance?
Expedia has 10 apartments to book in Defiance.
What can I expect from the weather during my trip to Defiance?
Weather is only one factor, but it can really affect your travel plans, especially if you're planning an extended stay in Defiance. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for Defiance is 48 inches.
What are the must-see places to visit in Defiance?
August A. Busch Memorial Conservation Area and Missouri River are a couple of scenic spots to enjoy the outdoors, whereas Historic Daniel Boone Home and Heritage Center is one of the cultural attractions. While here, Chandler Hill Vineyards and Sugar Creek Winery are other places worth a visit.
What's the best way to get to and around Defiance?
Knowing a bit about the transportation options can save you time when you get to your destination. Fly into St. Louis, MO (SUS-Spirit of St. Louis), which is located 7.5 mi (12 km) from the heart of the city. You can also search for flights into St. Louis Lambert Intl. Airport (STL), which is 23.5 mi (37.8 km) away. If you'd like to explore around the area, you may want a rental car for your journey.

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