A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

Apartments in Defiance for Rent

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Our top choices for Defiance apartments

1. The Foundry Flat | Industrial-Inspired 2-Bedroom

The Foundry Flat | Industrial-Inspired 2-Bedroom
St. Charles Historic District
$284 nightly
The price is $313
Aug 25 - Aug 26
Total with taxes and fees
The Foundry Flat | Industrial-Inspired 2-Bedroom

2. 2 Queen Beds | Non-Smoking, Kitchen

2 Queen Beds | Non-Smoking, Kitchen
Westport
9.8 out of 10, Exceptional, (38 reviews)
"Fantastic place!"
United States
Anonymous traveler
$60 nightly
The price is $70
Aug 30 - Aug 31
Total with taxes and fees
2 Queen Beds | Non-Smoking, Kitchen

3. Studio, sleeps 4, patio, short drive to Ski Resort, Six Flags & concert venues

Studio, sleeps 4, patio, short drive to Ski Resort, Six Flags & concert venues
Ballwin
7.8 out of 10, Good, (23 reviews)
"Nice and roomy place! The shower was a little messy when we went but everything else wemt well"
United States
alex h.
$145 nightly
The price is $155
Sep 6 - Sep 7
Total with taxes and fees
Studio, sleeps 4, patio, short drive to Ski Resort, Six Flags & concert venues

4. Family Home: Game Room & Huge Yard, Airport

Family Home: Game Room & Huge Yard, Airport
Maryland Heights
10.0 out of 10, Exceptional, (1 review)
"Very nice"
United States
Steven S.
$463 nightly
The price is $463
Sep 6 - Sep 7
Total with taxes and fees
Family Home: Game Room & Huge Yard, Airport

5. Quiet Neighborhood-Near Eats & Shops-Airport!

Quiet Neighborhood-Near Eats & Shops-Airport!
Brookside
10.0 out of 10, Exceptional, (2 reviews)
"This was an awesome place for 9 of us- plenty of rooms to sleep and bathrooms. The renter was very kind"
United States
Janet
$468 nightly
The price is $468
Aug 23 - Aug 24
Total with taxes and fees
Quiet Neighborhood-Near Eats & Shops-Airport!

6. Historic Main Street Studio | Dog-Friendly

Historic Main Street Studio | Dog-Friendly
St. Charles Historic District
9.2 out of 10, Wonderful, (37 reviews)
"Had a wonderful stay. It was a Monday night so parking was very easy and the room was clean and comfortable. I would recommend this place 100% "
United States
Sarah C.
$184 nightly
The price is $203
Aug 25 - Aug 26
Total with taxes and fees
Historic Main Street Studio | Dog-Friendly

7. 3BR Family+Game Retreat 8 min STL Airport/Westport

3BR Family+Game Retreat 8 min STL Airport/Westport
Maryland Heights
8.8 out of 10, Excellent, (11 reviews)
"Great stay! We had everything we needed and the communication was perfect!"
United States
Melodie B.
$430 nightly
The price is $430
Aug 25 - Aug 26
Total with taxes and fees
3BR Family+Game Retreat 8 min STL Airport/Westport

8. Studio | Lovely Suite Close to Edward Jones!

Studio | Lovely Suite Close to Edward Jones!
Westport
$198 nightly
The price is $226
Sep 13 - Sep 14
Total with taxes and fees
Studio | Lovely Suite Close to Edward Jones!

9. Amazing Renovated Historic Loft on Main Street

Amazing Renovated Historic Loft on Main Street
St. Charles Historic District
10.0 out of 10, Exceptional, (68 reviews)
"Lovely accommodations, very clean, well equipped, great location. "
United States
Emily B.
$245 nightly
The price is $262
Aug 23 - Aug 24
Total with taxes and fees
Amazing Renovated Historic Loft on Main Street

10. 1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed

1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed
Westport
9.8 out of 10, Exceptional, (40 reviews)
"Great spot!"
United States
Anonymous traveler
$60 nightly
The price is $70
Aug 30 - Aug 31
Total with taxes and fees
1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed

11. The Lofts of North Main Street

The Lofts of North Main Street
St. Charles Historic District
9.6 out of 10, Exceptional, (185 reviews)
"Great place to stay. Our go to when visiting St.Charles or STL"
United States
jeramy p.
$245 nightly
The price is $262
Aug 23 - Aug 24
Total with taxes and fees
The Lofts of North Main Street

12. 2 Queen Beds | Mobil Access Tub Nsmk Kitchen

2 Queen Beds | Mobil Access Tub Nsmk Kitchen
Westport
9.8 out of 10, Exceptional, (45 reviews)
"Great place to stay!"
United States
Anonymous traveler
$60 nightly
The price is $70
Aug 30 - Aug 31
Total with taxes and fees
2 Queen Beds | Mobil Access Tub Nsmk Kitchen

13. 6th street 101 - Walk to Main St

6th street 101 - Walk to Main St
St. Charles Historic District
10.0 out of 10, Exceptional, (3 reviews)
"Excellent"
United States
Scott N.
$255 nightly
The price is $286
Aug 27 - Aug 28
Total with taxes and fees
6th street 101 - Walk to Main St

14. Stylish 2BR Retreat - Concrete & Canopy

Stylish 2BR Retreat - Concrete & Canopy
St. Charles Historic District
9.0 out of 10, Wonderful, (2 reviews)
"Saturday night is load in downtown St Charles."
United States
Greg
$318 nightly
The price is $350
Aug 29 - Aug 30
Total with taxes and fees
Stylish 2BR Retreat - Concrete & Canopy

15. Historic Main St 2BR | Steps to Shops

Historic Main St 2BR | Steps to Shops
St. Charles Historic District
9.4 out of 10, Exceptional, (41 reviews)
"This property has a nice renovation while keeping a lot of its original character. Very clean and comfortable beds as well. The location couldn’t be better! We really enjoyed our stay."
United States
William O.
$390 nightly
The price is $429
Aug 25 - Aug 26
Total with taxes and fees
Historic Main St 2BR | Steps to Shops

16. Prime Loft of Main Street

Prime Loft of Main Street
St. Charles Historic District
9.8 out of 10, Exceptional, (116 reviews)
"Host was great. The cutest place in the perfect spot! "
United States
Anonymous traveler
$245 nightly
The price is $262
Aug 24 - Aug 25
Total with taxes and fees
Prime Loft of Main Street

17. Pet-Friendly Duplex | Historic Main

Pet-Friendly Duplex | Historic Main
St. Charles Historic District
10.0 out of 10, Exceptional, (25 reviews)
"Great location"
United States
todd p.
$231 nightly
The price is $254
Aug 30 - Aug 31
Total with taxes and fees
Pet-Friendly Duplex | Historic Main

18. Historic Main St 1BR | Walk to Dining & Nightlife

Historic Main St 1BR | Walk to Dining & Nightlife
St. Charles Historic District
9.0 out of 10, Wonderful, (22 reviews)
"Great place, very fun. I’d stay again for sure. "
United States
Michael C.
$246 nightly
The price is $270
Aug 25 - Aug 26
Total with taxes and fees
Historic Main St 1BR | Walk to Dining & Nightlife

19. Historic Main St. Customs House Upstairs Apartment

Historic Main St. Customs House Upstairs Apartment
St. Charles Historic District
9.6 out of 10, Exceptional, (39 reviews)
"Lovely place to stay!"
United States
Margaret A.
$349 nightly
The price is $384
Sep 6 - Sep 7
Total with taxes and fees
Historic Main St. Customs House Upstairs Apartment

20. 1st Capitol Mansion - Suite 401

1st Capitol Mansion - Suite 401
St. Charles Historic District
7.4 out of 10, Good, (9 reviews)
"Nice property and a great location to all the shops and restaurants that St. Charles has to offer. The place was clean and nicely updated. Will definitely stay here again!"
United States
Emily L.
$227 nightly
The price is $255
Aug 23 - Aug 24
Total with taxes and fees
1st Capitol Mansion - Suite 401
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Defiance Hotel Reviews

Find out more about Defiance

Defiance Apartments information

Number of reviews
707
Accommodation
113 Apartments
Lowest Price
$70
Highest Price
$468

Frequently asked questions

What's it like to stay at an apartment in Defiance?
You'll find 10 apartments to choose from in Defiance for your stay.
Why choose an apartment versus a traditional hotel?
Often more spacious than a traditional hotel room, an apartment includes a kitchen for convenient home-cooked meals. Apartments are ideal for families who want the conveniences of home, and also for couples who want something in a quieter part of town.
What's a favorite apartment for a stay in Defiance?
Here are some of the top apartments in the area: The Lofts of North Main Street: Located in St. Charles, 19.2 mi/30.8 km from the heart of Defiance. Includes free WiFi, sofa beds, and Smart TVs. Access to onsite laundry facilities is available on site. 2 Queen Beds | Non-Smoking, Kitchen: Located 18.7 mi/30.1 km away in Maryland Heights. Free WiFi and Smart TVs are included. Prime Loft of Main Street: Located in St. Charles, 19.2 mi/30.9 km away. Includes free WiFi, sofa beds, and Smart TVs. Access to onsite laundry facilities is available on site. Historic Main St 1BR | Walk to Dining & Nightlife: 19.1 mi/30.7 km away in St. Charles. Amenities include separate dining areas. Chic 1- Queen Bed, Non Smoking-Near Airport, Kitchen, Twin Bed: It's located in Overland, 20.7 mi/33.2 km from Defiance. Includes free WiFi, private balconies, and Smart TVs.
How many apartments will I be able to find in Defiance?
Expedia has 10 apartments to book in Defiance.
What can I expect from the weather during my trip to Defiance?
Weather is only one factor, but it can really affect your travel plans, especially if you're planning an extended stay in Defiance. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for Defiance is 48 inches.
What are the must-see places to visit in Defiance?
August A. Busch Memorial Conservation Area and Missouri River are a couple of scenic spots to enjoy the outdoors, whereas Historic Daniel Boone Home and Heritage Center is one of the cultural attractions. While here, Chandler Hill Vineyards and Sugar Creek Winery are other places worth a visit.
What's the best way to get to and around Defiance?
Knowing a bit about the transportation options can save you time when you get to your destination. Fly into St. Louis, MO (SUS-Spirit of St. Louis), which is located 7.5 mi (12 km) from the heart of the city. You can also search for flights into St. Louis Lambert Intl. Airport (STL), which is 23.5 mi (37.8 km) away. If you'd like to explore around the area, you may want a rental car for your journey.

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