A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

Apartments in Defiance for Rent

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Our top choices for Defiance apartments

1. Great for Business Travelers! Pool + Gym

Great for Business Travelers! Pool + Gym
O'Fallon
4.0 out of 10, (1 review)
"Property was dirty, kitchen hadn’t been cleaned. Microwave had food spilled all over inside. Place felt grimy."
United States
Jenny D.
$171 nightly
The price is $197
Oct 7 - Oct 8
Total with taxes and fees
Great for Business Travelers! Pool + Gym

2. Stylish1BRStudioCleanQuietandCozy

Stylish1BRStudioCleanQuietandCozy
Saint Charles
10.0 out of 10, Exceptional, (3 reviews)
"Room was very clean with little to no issues at all. Host was super easy to work with and get information from. This spot is within 15-20minutes OR LESS to anything you’d need to do in the ofallon and surrounding areas. I’d book it again if I needed to."
United States
Mike S.
$282 nightly
The price is $314
Oct 6 - Oct 7
Total with taxes and fees
Stylish1BRStudioCleanQuietandCozy

3. 2nd Street -Deck Suite (back entrance)

2nd Street -Deck Suite (back entrance)
Washington
10.0 out of 10, Exceptional, (9 reviews)
"Great comfortable mini apartment style."
United States
Ozzy
$166 nightly
The price is $186
Oct 6 - Oct 7
Total with taxes and fees
2nd Street -Deck Suite (back entrance)

4. Studio, sleeps 5, short drive to Hidden Valley Ski Resort, parks &concert venues

Studio, sleeps 5, short drive to Hidden Valley Ski Resort, parks &concert venues
Ballwin
7.8 out of 10, Good, (24 reviews)
"Rooms were clean and everything we needed for our stay."
United States
Keith K.
$138 nightly
The price is $147
Oct 8 - Oct 9
Total with taxes and fees
Studio, sleeps 5, short drive to Hidden Valley Ski Resort, parks &concert venues

5. Enjoyable 2-bedroom apartment at St. Peters; Near STL

Enjoyable 2-bedroom apartment at St. Peters; Near STL
St. Peters
$257 nightly
The price is $271
Oct 12 - Oct 13
Total with taxes and fees
Enjoyable 2-bedroom apartment at St. Peters; Near STL

6. 2nd Street Loft - Riverview

2nd Street Loft - Riverview
Washington
10.0 out of 10, Exceptional, (18 reviews)
"Everything was great room was very clean"
United States
Chance W.
$156 nightly
The price is $175
Oct 6 - Oct 7
Total with taxes and fees
2nd Street Loft - Riverview

7. Family Friendly w/ Game Room in Quiet Neighborhood

Family Friendly w/ Game Room in Quiet Neighborhood
Wentzville
10.0 out of 10, Exceptional, (2 reviews)
"Nice house for our week in Lake St. Louis area. Accurate description of what you are getting and clean house. Would stay again if we are back in the area"
United States
Campbell W.
$479 nightly
The price is $479
Oct 6 - Oct 7
Total with taxes and fees
Family Friendly w/ Game Room in Quiet Neighborhood

8. Otto's Third | River View Loft by Borgia Church

Otto's Third | River View Loft by Borgia Church
Washington
$329 nightly
The price is $371
Oct 6 - Oct 7
Total with taxes and fees
Otto's Third | River View Loft by Borgia Church

9. The FarmHouse 3bd/2ba B&B in MO Wine Country & Katy Trail

The FarmHouse 3bd/2ba B&B in MO Wine Country & Katy Trail
Marthasville
8.4 out of 10, Very good, (5 reviews)
"This was the perfect place for my friends and I to stay in Marthasville. Lots of space and amenities. We did not use the complimentary breakfast, but is a great addition. Would recommend to anyone staying in the area. "
United States
Adam K.
$443 nightly
The price is $480
Oct 6 - Oct 7
Total with taxes and fees
The FarmHouse 3bd/2ba B&B in MO Wine Country & Katy Trail

10. 2 Queen Beds | Non-Smoking, Kitchen

2 Queen Beds | Non-Smoking, Kitchen
Westport
8.6 out of 10, Excellent, (47 reviews)
"The price was cheap but I would not recommend the property. It is run down and depressing. My room had a deep depression under the carpeting near the bed that almost made me stumble. Upon checking in, I was charged extra fees I wasn't prepared for. There is no-one onsite during off hours to provide assistance."
United States
John
$56 nightly
The price is $64
Oct 18 - Oct 19
Total with taxes and fees
2 Queen Beds | Non-Smoking, Kitchen

11. Studio | Lovely Suite Close to Edward Jones!

Studio | Lovely Suite Close to Edward Jones!
Westport
$219 nightly
The price is $250
Oct 11 - Oct 12
Total with taxes and fees
Studio | Lovely Suite Close to Edward Jones!

12. Walk to Main | Pet-Friendly Yard & Workspace

Walk to Main | Pet-Friendly Yard & Workspace
St. Charles Historic District
10.0 out of 10, Exceptional, (12 reviews)
"Very close to downtown St. Charles and the Kati Trail. The home is cute and bed is comfortable. Easy check in process and fenced in back yard was nice to have."
United States
Jessica S.
$251 nightly
The price is $276
Oct 12 - Oct 13
Total with taxes and fees
Walk to Main | Pet-Friendly Yard & Workspace

13. Historic Main St. Customs House Upstairs Apartment

Historic Main St. Customs House Upstairs Apartment
St. Charles Historic District
9.6 out of 10, Exceptional, (39 reviews)
"Lovely place to stay!"
United States
Margaret A.
$318 nightly
The price is $350
Oct 8 - Oct 9
Total with taxes and fees
Historic Main St. Customs House Upstairs Apartment

14. Prime Loft of Main Street

Prime Loft of Main Street
St. Charles Historic District
9.8 out of 10, Exceptional, (120 reviews)
"Host was great. The cutest place in the perfect spot! "
United States
Anonymous traveler
$211 nightly
The price is $226
Oct 6 - Oct 7
Total with taxes and fees
Prime Loft of Main Street

15. Quiet 2BR Retreat on 7 Acres | Sleeps 6, Fast WiFi

Quiet 2BR Retreat on 7 Acres | Sleeps 6, Fast WiFi
Moscow Mills
10.0 out of 10, Exceptional, (14 reviews)
"Great place, nice neighborhood. "
United States
Julie L.
$269 nightly
The price is $269
Oct 20 - Oct 21
Total with taxes and fees
Quiet 2BR Retreat on 7 Acres | Sleeps 6, Fast WiFi

16. The Oak & Aura Retreat

The Oak & Aura Retreat
St. Charles Historic District
8.0 out of 10, Very good, (2 reviews)
"Great location, and very clean! Would stay here again!"
United States
Rachel B.
$276 nightly
The price is $304
Oct 8 - Oct 9
Total with taxes and fees
The Oak & Aura Retreat

17. Dog-Friendly 2BR | Walk to Main Street

Dog-Friendly 2BR | Walk to Main Street
Saint Charles
8.0 out of 10, Very good, (5 reviews)
"The best price-value ratio. Quiet neighborhood, close to the city center."
United States
Tamas P.
$273 nightly
The price is $301
Oct 11 - Oct 12
Total with taxes and fees
Dog-Friendly 2BR | Walk to Main Street

18. Pet-Friendly Duplex | Historic Main

Pet-Friendly Duplex | Historic Main
St. Charles Historic District
10.0 out of 10, Exceptional, (25 reviews)
"Great location"
United States
todd p.
$251 nightly
The price is $276
Oct 11 - Oct 12
Total with taxes and fees
Pet-Friendly Duplex | Historic Main

19. Historic Main Street Studio | Dog-Friendly

Historic Main Street Studio | Dog-Friendly
St. Charles Historic District
9.2 out of 10, Wonderful, (39 reviews)
"Had a wonderful stay. It was a Monday night so parking was very easy and the room was clean and comfortable. I would recommend this place 100% "
United States
Sarah C.
$184 nightly
The price is $203
Oct 12 - Oct 13
Total with taxes and fees
Historic Main Street Studio | Dog-Friendly

20. 1st Capitol Mansion - Suite 401

1st Capitol Mansion - Suite 401
St. Charles Historic District
7.4 out of 10, Good, (9 reviews)
"Nice property and a great location to all the shops and restaurants that St. Charles has to offer. The place was clean and nicely updated. Will definitely stay here again!"
United States
Emily L.
$225 nightly
The price is $253
Oct 6 - Oct 7
Total with taxes and fees
1st Capitol Mansion - Suite 401
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Defiance Hotel Reviews

Find out more about Defiance

Defiance Apartments information

Number of reviews
369
Accommodation
113 Apartments
Lowest Price
$64
Highest Price
$480

Frequently asked questions

What's it like to stay at an apartment in Defiance?
You'll find 10 apartments to choose from in Defiance for your stay.
Why choose an apartment versus a traditional hotel?
Often more spacious than a traditional hotel room, an apartment includes a kitchen for convenient home-cooked meals. Apartments are ideal for families who want the conveniences of home, and also for couples who want something in a quieter part of town.
What's a favorite apartment for a stay in Defiance?
Here are some of the top apartments in the area: 2 Queen Beds | Non-Smoking, Kitchen: Situated in Maryland Heights, 18.7 mi/30.1 km from the heart of Defiance. Includes free WiFi and Smart TVs. 1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed: Located 18.7 mi/30.1 km away in Maryland Heights. Free WiFi and Smart TVs are included. The Lofts of North Main Street: Located in St. Charles, 19.2 mi/30.8 km away. Includes free WiFi, sofa beds, and Smart TVs. Access to onsite laundry facilities is available on site. Driftwood Den | Boho 2BR | Dog-Friendly: It's located in St. Charles, 19 mi/30.6 km from Defiance. Includes free WiFi.
How many apartments will I be able to find in Defiance?
Expedia has 10 apartments to book in Defiance.
What can I expect from the weather during my trip to Defiance?
Weather is only one factor, but it can really affect your travel plans, especially if you're planning an extended stay in Defiance. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for Defiance is 48 inches.
What are the must-see places to visit in Defiance?
August A. Busch Memorial Conservation Area and Missouri River are a couple of scenic spots to enjoy the outdoors, whereas Historic Daniel Boone Home and Heritage Center is one of the cultural attractions. While here, Yellow Farmhouse Winery and Chandler Hill Vineyards are other places worth a visit.
What's the best way to get to and around Defiance?
Knowing a bit about the transportation options can save you time when you get to your destination. Fly into St. Louis, MO (SUS-Spirit of St. Louis), which is located 7.5 mi (12 km) from the heart of the city. You can also search for flights into St. Louis Lambert Intl. Airport (STL), which is 23.5 mi (37.8 km) away. If you'd like to explore around the area, you may want a rental car for your journey.

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