Top 10 Hotels in Frankford, MO (from $57) 2026 - Competitive Prices

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Our top choices for Frankford hotels

A hotel room with a large bed, a separate bathroom with a bathtub, and a desk with a chair.

A multi-level indoor pool area with a clear pool, multiple balconies, and a covered seating area.

A spacious hotel lobby with a central wooden table, seating, a treadmill, and a large potted plant.

A hotel kitchen with a buffet setup, including a coffee station and various food items.

1. Best Western On The River

Hannibal

Devin S

$110 nightly

$127 total

Sep 15 - Sep 16

Total with taxes and fees

An indoor swimming pool with a tiled floor, a rock wall, and a palm tree.

A lobby with leather sofas, a fireplace, a flat-screen TV, and a reception desk.

A spacious dining area with wooden flooring and tables, surrounded by glass walls and wooden paneling.

A hotel room with a bed, desk, chair, and a bathroom with a bathtub.

2. Quality Inn & Suites Hannibal West

Hannibal

Mohamed

$82 nightly

$96 total

Sep 27 - Sep 28

Total with taxes and fees

A hot tub with a rocky backdrop and a mural.

An outdoor patio area with wooden furniture, string lights, and umbrellas.

A cozy log cabin interior with a fireplace, wooden furniture, and a television mounted on the wall.

A restaurant with wooden walls, a bar area, and multiple seating arrangements.

3. Stoney Creek Inn Quincy

Quincy

luis

$123 nightly

$141 total

Sep 5 - Sep 6

Total with taxes and fees

A modern kitchen with wooden cabinets, a granite countertop, a coffee machine, a microwave, a toaster, and a refrigerator.

A lobby with a reception desk, seating area, and a staircase.

A compact living space with a kitchenette, a sofa, a patterned armchair, and a television.

4. Heritage Hotel Quincy

Quincy

Dustine

$65 nightly

$74 total

Oct 4 - Oct 5

Total with taxes and fees

A Sleep Inn & Suites building with a covered entrance, stone facade, and a flag.

A lobby with a reception desk, a seating area with sofas and armchairs, a large potted plant, and a door leading outside.

A hotel room with a bed, a desk, a chair, a sofa, and a TV mounted on the wall.

A modern lobby with a brown sofa, beige armchairs, a round table, and a floor lamp.

5. Sleep Inn & Suites Hannibal West

Hannibal

Patricia

$118 nightly

$137 total

Sep 27 - Sep 28

Total with taxes and fees

An indoor swimming pool with a tiled ceiling, multiple levels with windows, and seating areas around the pool.

A kitchen with a granite countertop, wooden cabinets, and a herringbone-patterned floor.

A hotel room with a bed, a desk with a chair, a television, and a desk lamp.

A gym with cardio equipment, mirrored walls, and a view of a Pepsi store outside.

6. Baymont by Wyndham Hannibal

Hannibal

Kimberly

$49 nightly

$57 total

Sep 13 - Sep 14

Total with taxes and fees

A modern reception area with a marble counter, a wooden panel with a light fixture, a fireplace, and a seating area with a sofa and chairs.

A spacious lobby with a fireplace, seating area, and large windows.

A Holiday Inn hotel with a modern facade, a covered entrance, and landscaped areas with shrubs.

A hotel room with a sofa, armchair, lamp, and a large mirror.

7. Holiday Inn Quincy East by IHG

Quincy

David

$127 nightly

$145 total

Sep 20 - Sep 21

Total with taxes and fees

A spacious lobby with a black leather sofa, a matching armchair, a coffee table, and a chandelier.

A spacious lobby with a fireplace, leather sofas, a coffee table, and a large window with blinds.

A building with a covered entrance and a sign indicating a clearance height of 13 feet.

A hotel room with two beds, a window with red curtains, an air conditioning unit, and two bedside lamps.

8. Motel 6 Hannibal, MO

Hannibal

Neal

$57 nightly

$66 total

Sep 12 - Sep 13

Total with taxes and fees

A Microtel Inn & Suites building with a stone facade, multiple windows, and a covered entrance area.

A hotel room with a bed, a desk, a sofa, a TV, and a window with curtains.

A dining area with a long table and six chairs, a kitchen counter with various items, and a window with blinds.

An indoor swimming pool with a tiled floor, wooden beams, and a view of the outdoors through large windows.

9. Microtel Inn & Suites by Wyndham Quincy Downtown/River Area

Quincy

Jenni

$68 nightly

$78 total

Sep 13 - Sep 14

Total with taxes and fees

A hotel room with a large bed, two bedside lamps, a modern bathroom, and a vibrant abstract painting on the wall.

A swimming pool with lounge chairs and a covered seating area.

A spacious bathroom with a large bathtub, a walk-in shower, and a vanity with a mirror.

A modern living room with a grey sofa, a white armchair, a coffee table, and a patterned rug. There is a kitchen in the background with white cabinets and a black door.

10. Lighthouse Inn & Suites

Hannibal

Kari

$199 nightly

$230 total

Sep 8 - Sep 9

Total with taxes and fees

A hotel room with a sofa, a bed, a desk, and a chair.

A modern living room with a flat-screen TV, two armchairs, a coffee table, and a fireplace.

A reception desk with a sign reading "American Inn by Wyndham".

A modern kitchen with granite countertops, wooden chairs, and a breakfast sign.

11. AmericInn by Wyndham Quincy

Quincy

Trisha

$85 nightly

$96 total

Sep 6 - Sep 7

Total with taxes and fees

A hotel room with a bed, a lamp, a mirror, and a door.

A sign for Town & Country Inn and Suites with a parking lot and a building in the background.

A grand, circular staircase with white balustrades and a chandelier in the center.

A swimming pool with lounge chairs and sunbathing areas.

12. Town & Country Inn and Suites

Quincy

Tracy

A hotel room with a bed, a sofa, a desk, and a lamp.

A hotel reception area with a wooden reception desk, a red chair, and a carpeted floor.

A Comfort Inn & Suites hotel with a stone facade, a covered entrance, and a clear blue sky.

A restaurant with multiple tables and chairs, an exit sign, and a counter area.

13. Comfort Inn & Suites - Hannibal

Hannibal

Sandra

$79 nightly

$91 total

Sep 20 - Sep 21

Total with taxes and fees

A hotel room with two beds, a wooden headboard, a nightstand with a phone and lamp, and a large sunset painting above the beds.

A laundry room with a washing machine, dryer, and a shelf with detergent bottles.

A corner kitchenette with a refrigerator, coffee maker, and food display.

14. Days Inn by Wyndham Hannibal

Hannibal

PERRY

$56 nightly

$65 total

Sep 13 - Sep 14

Total with taxes and fees

A modern hotel with a flat roof, multiple windows, and a sign indicating it is a Super 8 hotel.

A modern dining area with round tables and chairs, a flat-screen TV mounted on the wall, and a brick accent wall.

A long hallway with a patterned carpet, wooden paneling on the walls, and a ceiling light.

A patio with red Adirondack chairs and a table, surrounded by a pebble border.

15. Super 8 by Wyndham Hannibal

Hannibal

Betty

$62 nightly

$71 total

Oct 4 - Oct 5

Total with taxes and fees

A hotel lobby with a dining area, a bar, and a fireplace.

A reception desk with a black countertop, wooden paneling, and a patterned glass partition.

An indoor swimming pool with clear blue water, yellow and white lounge chairs, and a clock on the wall.

A snack shelf stocked with various chips and snacks, a mini-fridge with beverages, and a small refrigerator with hot food items.

16. Fairfield Inn & Suites Quincy

Quincy

Cathy

$125 nightly

$143 total

Sep 13 - Sep 14

Total with taxes and fees

A hotel room with two beds, a desk, a chair, a TV, and a large window with curtains.

A hotel room with two beds, a nightstand with a lamp, a large window with curtains, and a patterned carpet.

A modern building with a flat roof, large windows, and a covered entrance area.

A coffee shop display with a white cup, two Starbucks branded bags, and a branded coffee grinder.

17. The Atrium Hotel on Third

Quincy

Ronda

A living room with a sofa, coffee table, and patterned rug. There are large windows with blinds, a chandelier, and a view of the outside.

A building with a covered entrance, American flag, and a sign indicating it's open.

A hotel hallway with a patterned carpet, doors, and a sign indicating room number 101.

A hotel room with two beds, a television, a lamp, and a painting on the wall.

18. FairBridge Inn Express, Monroe City

Monroe City

Darrin J.

$85 nightly

$92 total

Sep 6 - Sep 7

Total with taxes and fees

A large indoor swimming pool with multiple levels of balconies, surrounded by seating areas and potted plants.

A kitchen with wooden cabinets, a granite countertop, and various food items and kitchen appliances.

A clean, modern reception area with a reception desk, a clock, and a potted plant.

A modern building with a red awning, a parking lot, and a sign indicating an entrance.

19. Howard Johnson BY Wyndham Hannibal

Hannibal

Debbie

$61 nightly

$71 total

Sep 7 - Sep 8

Total with taxes and fees

A gazebo with a table and benches, surrounded by trees and a body of water.

A two-story building with a flat roof and a covered entrance. There are two cars parked in front, and a truck is visible on the left.

A hotel room with a bed, two sofas, a small table, a desk with a chair, a TV, and a potted plant.

A hotel room with a bed, a desk, a chair, a television, a microwave, and a lamp.

20. River's Edge Motel

Louisiana

Paul

$83 nightly

$94 total

Sep 6 - Sep 7

Total with taxes and fees

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Top Frankford Hotel Reviews

Lighthouse Inn & Suites

10/10 Excellent

"Last minute getaway to Hannibal. Wonderful room, it was small, but decorated very cool. Cleanest room, and hot tub I’ve ever seen. It’s a block off the main downtown area. Small, clean pool. Staff was Great!"

Super 8 by Wyndham Hannibal

10/10 Excellent

"Staff was amazing. Not much breakfast but great for the price."

Motel 6 Hannibal, MO

10/10 Excellent

"Very pleasant experience, reasonably priced. Room was clean and spacious. A/C was cold, staff was very helpful! 10/10 recommend."

Comfort Inn & Suites - Hannibal

10/10 Excellent

"Breakfast"

Peaceful, Country Cottage with Open Floor Plan

10/10 Excellent

"Beautiful location with surrounding nature. Exceedingly clean well kept property. Would strongly recommend this house for friends and family visiting the Quincy area. I couldn't be more satisfied with my stay."

Best Western On The River

8/10 Good

"This hotel is very close to all the downtown attractions within walking distance. Very clean. We were looking forward to enjoying time in the hot tub in the evening but it broke down the day we arrived. We were very disappointed to say the least. The beds were very comfortable."

Sleep Inn & Suites Hannibal West

8/10 Good

"Breakfast was good. Hotel was clean and has very comfortable beds."

Riverside Inn Hannibal

10/10 Excellent

"a surprising gem. External pictures were not impressive, But all the ratings were 10’s. So we went with the ratings and were delighted. approximately 15 steps (we were not aware of an elevator). 5 minute walk to the river boat tour/cruise. Mexican restaurant downstairs. Everything in the room was “right”. Would definitely return if in Hannibal."

River's Edge Motel

8/10 Good

"Jew of the sunrise over the river was great! AC in the room was pretty noisy… I’d stay there again."

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