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La Mesa Vacation Rentals

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Our top choices for La Mesa vacation rentals

Mediterranean-inspired 1BR Guesthouse - Full Kitchen, Workspace & Garden

Mediterranean-inspired 1BR Guesthouse - Full Kitchen, Workspace & Garden
Mount Helix
10.0 out of 10, Exceptional, (1 review)
"We really enjoyed staying here. Clean and roomy and has everything you’d need. "
United States
Linda R.
$392 nightly
The price is $392
Jul 8 - Jul 9
Total with taxes and fees
Mediterranean-inspired 1BR Guesthouse - Full Kitchen, Workspace & Garden

SDSU/Downtown <10 Min - GameRoom - Fire Pit - Free Parking - Easy Freeway Access

SDSU/Downtown <10 Min - GameRoom - Fire Pit - Free Parking - Easy Freeway Access
La Mesa
9.0 out of 10, Wonderful, (10 reviews)
"Really nice spot. Thanks for letting us stay & enjoy your home! "
United States
Kenneth K.
$530 nightly
The price is $577
Jun 30 - Jul 1
Total with taxes and fees
SDSU/Downtown <10 Min - GameRoom - Fire Pit - Free Parking - Easy Freeway Access

Spacious King Bed Ranch Style, Prime Area, 4BR/2BTH

Spacious King Bed Ranch Style, Prime Area, 4BR/2BTH
La Mesa
10.0 out of 10, Exceptional, (1 review)
$451 nightly
The price is $491
Jul 5 - Jul 6
Total with taxes and fees
Spacious King Bed Ranch Style, Prime Area, 4BR/2BTH

Private Casita • No Extra Fees • Spa • Beach • AC

Private Casita • No Extra Fees • Spa • Beach • AC
La Mesa
$181 nightly
The price is $181
Jul 1 - Jul 2
Total with taxes and fees
Private Casita • No Extra Fees • Spa • Beach • AC

25% off, Private Pool•Hot Tub•BBQ•Chef’s Kitchen•CentralSD•4 mins to SDSU

25% off, Private Pool•Hot Tub•BBQ•Chef’s Kitchen•CentralSD•4 mins to SDSU
La Mesa
10.0 out of 10, Exceptional, (17 reviews)
"Great stay, owner was very responsive to a few minor issues."
United States
Robert B.
$615 nightly
The price is $615
Jul 1 - Jul 2
Total with taxes and fees
25% off, Private Pool•Hot Tub•BBQ•Chef’s Kitchen•CentralSD•4 mins to SDSU

Large 3BR Oasis with Pool and Games!

Large 3BR Oasis with Pool and Games!
Mount Helix
9.0 out of 10, Wonderful, (2 reviews)
"Yes, Excellent workspace."
United States
Stanley H.
$574 nightly
The price is $574
Jul 6 - Jul 7
Total with taxes and fees
Large 3BR Oasis with Pool and Games!

New Modern 2BR Home with Movie theater, & Big Yard

New Modern 2BR Home with Movie theater, & Big Yard
Mount Helix
$501 nightly
The price is $521
Jul 6 - Jul 7
Total with taxes and fees
New Modern 2BR Home with Movie theater, & Big Yard

Ranch-Style w Gated Yard, 4 Parking, 4 Bedroom 3 Bathroom

Ranch-Style w Gated Yard, 4 Parking, 4 Bedroom 3 Bathroom
La Mesa
$541 nightly
The price is $541
Jul 20 - Jul 21
Total with taxes and fees
Ranch-Style w Gated Yard, 4 Parking, 4 Bedroom 3 Bathroom

Mt. Nebo Oasis in La Mesa w/ Wraparound Deck

Mt. Nebo Oasis in La Mesa w/ Wraparound Deck
Windsor Hills
9.2 out of 10, Wonderful, (14 reviews)
"The location for this rental was perfect for our stay as it was walking distance to family. The views are fantastic, the beds were comfortable, and the pool/patio were nice. The photos and descriptions of the place were aligned with our experience."
United States
Megan
$680 nightly
The price is $738
Jul 29 - Jul 30
Total with taxes and fees
Mt. Nebo Oasis in La Mesa w/ Wraparound Deck

Mt. Nebo Oasis in La Mesa w/ Wraparound Deck

Mt. Nebo Oasis in La Mesa w/ Wraparound Deck
3.0 star property
Windsor Hills
$670 nightly
The price is $737
Jul 29 - Jul 30
Total with taxes and fees
Mt. Nebo Oasis in La Mesa w/ Wraparound Deck

King Bed, Big Yard, Prime Area, Ranch, 4BR/3Bth

King Bed, Big Yard, Prime Area, Ranch, 4BR/3Bth
La Mesa
$383 nightly
The price is $417
Jul 7 - Jul 8
Total with taxes and fees
King Bed, Big Yard, Prime Area, Ranch, 4BR/3Bth

City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.8 out of 10, Exceptional, (167 reviews)
"Nice and very friendly staff was a great stay"
United States
Alexander
$186 nightly
The price is $210
Jul 1 - Jul 2
Total with taxes and fees
City24 Hotel Little Italy Mission Hills

Little Italy Inn - Limited Service Apart Hotel

Little Italy Inn - Limited Service Apart Hotel
2.5 star property
Downtown San Diego
8.4 out of 10, Very Good, (161 reviews)
"the rooms were clean, everything was located so close less than 10 mins away! i loved it for our stay"
United States
annalisa
$116 nightly
The price is $132
Jun 30 - Jul 1
Total with taxes and fees
Little Italy Inn - Limited Service Apart Hotel

Hideaway in the heart of San Diego!

Hideaway in the heart of San Diego!
Mid-City
10.0 out of 10, Exceptional, (7 reviews)
"Welcoming, clean, and helpful suggestions from host. Would stay here again."
United States
Mathew W.
$314 nightly
The price is $349
Jul 5 - Jul 6
Total with taxes and fees
Hideaway in the heart of San Diego!

Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Uptown Inn by Vantaggio - Limited Service Apart-Hotel
2.5 star property
Hillcrest
8.4 out of 10, Very Good, (397 reviews)
"Great place to stay. Clean, friendly staff."
United States
Heber
$108 nightly
The price is $122
Jun 30 - Jul 1
Total with taxes and fees
Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Adorable 1 bedroom house 8 min from La Jolla!

Adorable 1 bedroom house 8 min from La Jolla!
Bay Ho
10.0 out of 10, Exceptional, (54 reviews)
"Everything was in great shape."
United States
emma c.
$261 nightly
The price is $290
Jul 1 - Jul 2
Total with taxes and fees
Adorable 1 bedroom house 8 min from La Jolla!

Cozy 2-Bedroom Cottage Near Balboa Park

Cozy 2-Bedroom Cottage Near Balboa Park
Mid-City
8.6 out of 10, Excellent, (10 reviews)
$316 nightly
The price is $352
Jul 5 - Jul 6
Total with taxes and fees
Cozy 2-Bedroom Cottage Near Balboa Park

Tranquil Private North San Diego Cottage/Guest 1 House

Tranquil Private North San Diego Cottage/Guest 1 House
Poway
9.0 out of 10, Wonderful, (34 reviews)
"Everything was wonderful. Beautiful property and hosts were great people."
United States
John K.
$429 nightly
The price is $429
Jun 30 - Jul 1
Total with taxes and fees
Tranquil Private North San Diego Cottage/Guest 1 House

Chic apartment with AC, pool and fitness room in sunny San Diego

Chic apartment with AC, pool and fitness room in sunny San Diego
Downtown San Diego
8.8 out of 10, Excellent, (12 reviews)
"Secured parking, great location to just about anywhere, and the pool/spa area were great bonuses!"
United States
Michelle S.
$192 nightly
The price is $215
Jul 1 - Jul 2
Total with taxes and fees
Chic apartment with AC, pool and fitness room in sunny San Diego

Private Resort "La Casita" Spa and Mini Golf Course

Private Resort "La Casita" Spa and Mini Golf Course
ALPINE
10.0 out of 10, Exceptional, (28 reviews)
$288 nightly
The price is $309
Jul 5 - Jul 6
Total with taxes and fees
Private Resort "La Casita" Spa and Mini Golf Course
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top La Mesa Hotel Reviews

Find out more about La Mesa

Everything you need to know about La Mesa vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the La Mesa vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect La Mesa vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

La Mesa vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in La Mesa. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit La Mesa in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $111 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on La Mesa rentals

At Expedia, we put the best La Mesa vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top La Mesa rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream La Mesa vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around La Mesa. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Are there vacation rentals in La Mesa?

Yes, you can find vacation rentals in La Mesa near La Mesa Memorial Fine Arts Center, or you can choose a secluded option if you'd like a relaxing place to stay. Visitors like the top-notch restaurants and shops in La Mesa. Leave some time to check out the zoo and entertainment venues during your trip.

What are some of the best vacation rentals that La Mesa has to offer?

Luxurious Estate Home-Sumptuous Views - Resort Like!!!: This La Mesa vacation home rental offers a balcony, a garden, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. You and your friends and family can relax into your vacation with amenities like a hot tub.

How many vacation rentals are there in La Mesa?

With 72 Expedia vacation rentals, you're sure to find just the right place for your La Mesa stay.

What can I see and do in La Mesa?

Explore the area and cultural attractions such as Computer Museum of America, or visit a family-friendly sight such as San Diego Zoo. While in the area, you can also visit popular places like Petco Park and Hotel del Coronado.

What are vacation rentals like in La Mesa?

Vacation rentals are privately owned properties you can book for several days or more in La Mesa. Vacation rentals feature amenities such as WiFi and washers and dryers so you'll have everything you need. If you're concerned about a clean environment, vacation rentals can provide a sense of safety away from shared hotel elevators and busy lobbies while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a traditional hotel, which makes a vacation rental a great choice for families.