Title: La Mesa Vacation Rentals from $102: Search Short-Term Rentals | Expedia.com [La Mesa Travel Guide](https://expedia.com/La-Mesa.dx8484)[Hotels in La Mesa](https://expedia.com/La-Mesa-Hotels.d8484.Travel-Guide-Hotels)[Flights to La Mesa](https://expedia.com/Cheap-Flights-To-La-Mesa.d8484.Travel-Guide-Flights)[Things to do in La Mesa](https://expedia.com/Things-To-Do-In-La-Mesa.d8484.Travel-Guide-Activities)[Car Rentals in La Mesa](https://expedia.com/Car-Rentals-In-La-Mesa.d8484.Car-Rental-Guide)[La Mesa Vacation Packages](https://expedia.com/La-Mesa.d8484.Destination-Travel-Guides) ![View from Mount Helix, in La Mesa, near San Diego, California](https://images.trvl-media.com/place/8484/0fa3bc38-9bbb-4533-9232-a1a6e7720bc2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/8484/0fa3bc38-9bbb-4533-9232-a1a6e7720bc2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_bundle_and_save.svg) ### Bundle & Save Get more, spend less whenever you see Bundle & Save deals - ![](https://a.travel-assets.com/travel-assets-manager/pictograms-expedia/light__onekey.svg) ### OneKeyCash Earn OneKeyCash on all your eligible bookings - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_ftc.svg) ### Upfront pricing We are not like the others - we include taxes and fees ## Check prices for these dates In two weeks [Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=8484&startDate=2026-03-27&endDate=2026-03-29&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [May 8 - May 10](https://www.expedia.com/Hotel-Search?regionId=8484&startDate=2026-05-08&endDate=2026-05-10&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [Jun 5 - Jun 7](https://www.expedia.com/Hotel-Search?regionId=8484&startDate=2026-06-05&endDate=2026-06-07&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [Jul 3 - Jul 5](https://www.expedia.com/Hotel-Search?regionId=8484&startDate=2026-07-03&endDate=2026-07-05&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for La Mesa vacation rentals ![Dining](https://images.trvl-media.com/lodging/109000000/108780000/108777000/108776954/90a8461d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/109000000/108780000/108777000/108776954/d3a64ea8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/109000000/108780000/108777000/108776954/47c69029.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/109000000/108780000/108777000/108776954/1fe8182b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sunnyside Resort Spa, Beach, Zoo, Arcade [](https://www.expedia.com/La-Mesa-Hotels-3-Bed2b-Sunnyside-Villa-Sauna.h108776954.Hotel-Information) La Mesa 9.6/10 Exceptional (18 reviews) "The house was very clean and located in a family-friendly neighborhood. Very nice stay.thank you!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jenna A. $376 nightly $384 total Mar 11 - Mar 12 Total with taxes and fees [](https://www.expedia.com/La-Mesa-Hotels-3-Bed2b-Sunnyside-Villa-Sauna.h108776954.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/69000000/68870000/68864800/68864775/d11be534.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/69000000/68870000/68864800/68864775/9dc67061.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, desk, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/69000000/68870000/68864800/68864775/8f91d728.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/69000000/68870000/68864800/68864775/7ebe9d8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 3 Bedroom House - Fire Pit Table, BBQ - 10 Guests [](https://www.expedia.com/La-Mesa-Hotels-3-Bedroom-House-Fire-Pit-Table.h68864775.Hotel-Information) La Mesa 9.2/10 Wonderful (15 reviews) "We had a great time staying at the Fountain House. Everything was clean and comfortable. The neighborhood was quiet and located ideally for the various places we went while in La Mesa/SD area. The decor was very welcoming and up to date. We loved having our coffee in the front yard, which was refreshing with lots of shade. All details for our stay were clear, and all the things we needed were available (ice, glass ware, cooking utensils etc). We have zero complaints :) Thank you for hosting us." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chanel M. [](https://www.expedia.com/La-Mesa-Hotels-3-Bedroom-House-Fire-Pit-Table.h68864775.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/110000000/109720000/109718900/109718812/7f0c02f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/110000000/109720000/109718900/109718812/ef0e899c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/110000000/109720000/109718900/109718812/9062ac6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, table tennis](https://images.trvl-media.com/lodging/110000000/109720000/109718900/109718812/dca5b67c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SDSU/Downtown <10 Min - GameRoom - Fire Pit - Free Parking - Easy Freeway Access [](https://www.expedia.com/La-Mesa-Hotels-SDSUDowntown-10-Min-GameRoom-Fire-Pit-Free-Parking-Easy-Freeway-Access.h109718812.Hotel-Information) La Mesa 8.8/10 Excellent (8 reviews) "The host was welcoming and the home is well kept." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shalisha H. $381 nightly $381 total Mar 11 - Mar 12 Total with taxes and fees [](https://www.expedia.com/La-Mesa-Hotels-SDSUDowntown-10-Min-GameRoom-Fire-Pit-Free-Parking-Easy-Freeway-Access.h109718812.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/106000000/105390000/105380700/105380638/db3a0fed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/106000000/105390000/105380700/105380638/5d897517.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/106000000/105390000/105380700/105380638/5e8ce6dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/106000000/105390000/105380700/105380638/5efb1585_edited_2105.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### An elegant, fully furnished guest house for 2-4 guest in San Diego [](https://www.expedia.com/La-Mesa-Hotels-An-Elegant.h105380638.Hotel-Information) Mount Helix 9.0/10 Wonderful (2 reviews) "We love a simple no-nonsense place and this was perfect for us. The host is very responsive and was constantly checking in with us on what else we need to be comfortable to stay here. The area is close a lot of nice restaurants so that was a plus. We would love to stay here next time we visit San Diego." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Darakhshan T. $277 nightly $293 total Mar 17 - Mar 18 Total with taxes and fees [](https://www.expedia.com/La-Mesa-Hotels-An-Elegant.h105380638.Hotel-Information) ![Smart TV, offices](https://images.trvl-media.com/lodging/118000000/117640000/117631200/117631162/a07f546d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/118000000/117640000/117631200/117631162/6a53bc9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/118000000/117640000/117631200/117631162/c7979699.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, offices](https://images.trvl-media.com/lodging/118000000/117640000/117631200/117631162/94aa6cc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 25% off, Chic Casita • Hot tub • BBQ • 4 min to SDSU [](https://www.expedia.com/La-Mesa-Hotels-Cozy-Private-Guest-House-In-La-Mesa.h117631162.Hotel-Information) La Mesa 10/10 Exceptional (6 reviews) "The casita was beautifully decorated and had all the amenities needed for a nice weekend getaway. Amit was a great host as well. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sarah L. $464 nightly $464 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/La-Mesa-Hotels-Cozy-Private-Guest-House-In-La-Mesa.h117631162.Hotel-Information) ![Private kitchen](https://images.trvl-media.com/lodging/124000000/123280000/123270200/123270168/c0a3b2e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/124000000/123280000/123270200/123270168/6a3e789b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/124000000/123280000/123270200/123270168/w6012h4016x0y0-36206196.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/124000000/123280000/123270200/123270168/1d733067.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### New Modern 2BR Home with Movie theater, & Big Yard [](https://www.expedia.com/La-Mesa-Hotels-New-Modern-2BR-Home-With-Movie-Theater.h123270168.Hotel-Information) Mount Helix $497 nightly $516 total Mar 11 - Mar 12 Total with taxes and fees [](https://www.expedia.com/La-Mesa-Hotels-New-Modern-2BR-Home-With-Movie-Theater.h123270168.Hotel-Information) ![Beach](https://images.trvl-media.com/lodging/123000000/122950000/122947400/122947388/f7600228.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/123000000/122950000/122947400/122947388/0582c090.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/123000000/122950000/122947400/122947388/519d5bac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, video games, books, music library](https://images.trvl-media.com/lodging/123000000/122950000/122947400/122947388/6fc7575b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 4BR/3Bth King Bed, Big Yard, Prime Area, Ranch [](https://www.expedia.com/La-Mesa-Hotels-4BR3Bth-King-Bed.h122947388.Hotel-Information) La Mesa $372 nightly $405 total Mar 11 - Mar 12 Total with taxes and fees [](https://www.expedia.com/La-Mesa-Hotels-4BR3Bth-King-Bed.h122947388.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/128000000/127080000/127073700/127073615/5a4302a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/128000000/127080000/127073700/127073615/6aca7e5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/128000000/127080000/127073700/127073615/5a060336.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/128000000/127080000/127073700/127073615/6f203d05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Mesa Hillside Escape [](https://www.expedia.com/La-Mesa-Hotels-Charming-4-Bedroom-House-With-A-Stunning-View.h127073615.Hotel-Information) Mount Helix $411 nightly $411 total Mar 17 - Mar 18 Total with taxes and fees [](https://www.expedia.com/La-Mesa-Hotels-Charming-4-Bedroom-House-With-A-Stunning-View.h127073615.Hotel-Information) ![TV](https://images.trvl-media.com/lodging/122000000/121820000/121817600/121817509/875f5f69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/122000000/121820000/121817600/121817509/c5c93f61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, oven, stovetop](https://images.trvl-media.com/lodging/122000000/121820000/121817600/121817509/52aafcdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/122000000/121820000/121817600/121817509/e38e93c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mediterranean-inspired 1BR Guesthouse - Full Kitchen, Workspace & Garden [](https://www.expedia.com/La-Mesa-Hotels-Mediterranean-Inspired-1BR-Guesthouse-Full-Kitchen.h121817509.Hotel-Information) Mount Helix $327 nightly $327 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/La-Mesa-Hotels-Mediterranean-Inspired-1BR-Guesthouse-Full-Kitchen.h121817509.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/95000000/94890000/94882700/94882681/20f9eff8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/95000000/94890000/94882700/94882681/bdb795e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, offices](https://images.trvl-media.com/lodging/95000000/94890000/94882700/94882681/d16dcebd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, travel crib, WiFi](https://images.trvl-media.com/lodging/95000000/94890000/94882700/94882681/37da3ff8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxury Dream Home Stunning 360 Views of SD [](https://www.expedia.com/La-Mesa-Hotels-Stunning-Brand-New-Top-Of-Mtn-2BR-Zen-Retreat.h94882681.Hotel-Information) Mount Helix $1,541 nightly $1,629 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/La-Mesa-Hotels-Stunning-Brand-New-Top-Of-Mtn-2BR-Zen-Retreat.h94882681.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/95000000/94890000/94880400/94880364/d15f1cc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/95000000/94890000/94880400/94880364/b9c34ce6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/95000000/94890000/94880400/94880364/30526649.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, offices](https://images.trvl-media.com/lodging/95000000/94890000/94880400/94880364/4e1012c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxury Resort Style Dream Villa w/Best Views of SD [](https://www.expedia.com/La-Mesa-Hotels-Luxury-Resort-Style-Dream-Villa-WBest-Views-Of-SD.h94880364.Hotel-Information) Mount Helix $1,797 nightly $1,895 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/La-Mesa-Hotels-Luxury-Resort-Style-Dream-Villa-WBest-Views-Of-SD.h94880364.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/118000000/117890000/117882600/117882556/f678fc72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books](https://images.trvl-media.com/lodging/118000000/117890000/117882600/117882556/1c7c661d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/118000000/117890000/117882600/117882556/cc51f8fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books](https://images.trvl-media.com/lodging/118000000/117890000/117882600/117882556/ce3766b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Central SD• Luxury Home+Casita, Pool•Hot tub•BBQ•Sleeps10 [](https://www.expedia.com/La-Mesa-Hotels-Private-Pool-House-Guest-House.h117882556.Hotel-Information) La Mesa $1,360 nightly $1,360 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/La-Mesa-Hotels-Private-Pool-House-Guest-House.h117882556.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/112000000/111460000/111456400/111456372/8e3d00cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/112000000/111460000/111456400/111456372/eb51f0ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/112000000/111460000/111456400/111456372/fb16185a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/112000000/111460000/111456400/111456372/bc17e806.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 25% off, Private Pool•Hot Tub•BBQ•Chef’s Kitchen•CentralSD•4 mins to SDSU [](https://www.expedia.com/La-Mesa-Hotels-Boho-Tides-2-Bed-House-With-Resort-Style-Pool-In-Tranquil-San-Diego.h111456372.Hotel-Information) La Mesa 10/10 Exceptional (16 reviews) "Great stay, owner was very responsive to a few minor issues." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert B. $740 nightly $740 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/La-Mesa-Hotels-Boho-Tides-2-Bed-House-With-Resort-Style-Pool-In-Tranquil-San-Diego.h111456372.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/124000000/123270000/123265200/123265181/3f30927d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/124000000/123270000/123265200/123265181/c54c9ca8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/124000000/123270000/123265200/123265181/08904848.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/124000000/123270000/123265200/123265181/ae727f64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Mesa New 3BR Oasis with Pool and Games! [](https://www.expedia.com/La-Mesa-Hotels-La-Mesa-New-3BR-Oasis-With-Pool-And-Games.h123265181.Hotel-Information) Mount Helix 9.0/10 Wonderful (2 reviews) "Yes, Excellent workspace." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stanley H. $597 nightly $597 total Mar 31 - Apr 1 Total with taxes and fees [](https://www.expedia.com/La-Mesa-Hotels-La-Mesa-New-3BR-Oasis-With-Pool-And-Games.h123265181.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/128000000/127190000/127188800/127188702/d70cd7f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room](https://images.trvl-media.com/lodging/128000000/127190000/127188800/127188702/59cae69e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/128000000/127190000/127188800/127188702/84335655.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/128000000/127190000/127188800/127188702/0b1b046c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa de la Playa! [](https://www.expedia.com/San-Diego-Hotels-Casa-De-La-Playa.h127188702.Hotel-Information) Pacific Beach $426 nightly $473 total Mar 16 - Mar 17 Total with taxes and fees [](https://www.expedia.com/San-Diego-Hotels-Casa-De-La-Playa.h127188702.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/38000000/37020000/37014000/37013939/6dd046c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/38000000/37020000/37014000/37013939/596ef00a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/38000000/37020000/37014000/37013939/cd12e163.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/38000000/37020000/37014000/37013939/9ab8a533.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spring Sale in Bettie Blue RV fun! [](https://www.expedia.com/El-Cajon-Hotels-Flashback-Family-Fun-At-The-Retro-RV-Adventure-Glamp-In-Style-In-Bettie-Blue.h37013939.Hotel-Information) El Cajon 9.8/10 Exceptional (16 reviews) "We came down to Cali to get away from the Canadian cold and this little place was perfect for our family of three. Great location , cozy comfy Christmas for us :) " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Niki P. $161 nightly $175 total Mar 12 - Mar 13 Total with taxes and fees [](https://www.expedia.com/El-Cajon-Hotels-Flashback-Family-Fun-At-The-Retro-RV-Adventure-Glamp-In-Style-In-Bettie-Blue.h37013939.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/17900/17865/f34abdc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/1000000/20000/17900/17865/97d1106b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/20000/17900/17865/03c11edc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/20000/17900/17865/41d4439d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott Vacation Club®, San Diego [](https://www.expedia.com/San-Diego-Hotels-Marriott-Vacation-Club-Pulse.h17865.Hotel-Information) Downtown San Diego 9.4/10 Exceptional (1,027 reviews) "Great place to stay!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Rose Marie JOy $161 nightly $187 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/San-Diego-Hotels-Marriott-Vacation-Club-Pulse.h17865.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/dd5fc603.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/b4a5f1e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/9a181764.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![55-inch flat-screen TV with cable channels, Netflix, Hulu](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/4123f91e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sentral Gaslamp Quarter [](https://www.expedia.com/San-Diego-Hotels-Sentral-Gaslamp-Quarter.h114116366.Hotel-Information) Downtown San Diego 9.4/10 Exceptional (752 reviews) "Great place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) KELLY $160 nightly $186 total Mar 11 - Mar 12 Total with taxes and fees [](https://www.expedia.com/San-Diego-Hotels-Sentral-Gaslamp-Quarter.h114116366.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/850000/842000/841962/ae7c0c5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/850000/842000/841962/46a9ae00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/850000/842000/841962/37bf8b39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/850000/842000/841962/31020b74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Coronado Beach Resort [](https://www.expedia.com/Coronado-Hotels-Coronado-Beach-Resort.h841962.Hotel-Information) Historic Downtown Coronado 9.0/10 Wonderful (774 reviews) "Ideal location walkable to many restaurants and the beach. Great spot and lovely staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Justine $239 nightly $263 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Coronado-Hotels-Coronado-Beach-Resort.h841962.Hotel-Information) ![Deluxe 2 King Bedrooms, Multiple Beds, Sleeps 11ppl | Terrace/patio](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/6ef835b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/6c7bbd52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/333bf268.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/1b9a69bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### City24 Hotel Little Italy Mission Hills [](https://www.expedia.com/San-Diego-Hotels-City24-Hotel-Little-Italy-Mission-Hill.h104140458.Hotel-Information) Middletown 9.6/10 Exceptional (127 reviews) "Very clean, quiet, walking distance to great food" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amanda $191 nightly $215 total Apr 9 - Apr 10 Total with taxes and fees [](https://www.expedia.com/San-Diego-Hotels-City24-Hotel-Little-Italy-Mission-Hill.h104140458.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-24&endDate=2026-03-25®ionId=8484&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=VR_SPRING_PROMO_8484) ## Find vacation rentals that suit your style Private vacation homes [](https://www.expedia.com/Hotel-Search?destination=La+Mesa%2C+California%2C+United+States+of+America®ionId=8484&latLong=32.76783%2C-117.023086&adults=2&startDate=2026-06-07&d1=2026-06-07&endDate=2026-06-10&d2=2026-06-10&lodging=VACATION_HOME) Aparthotels [](https://www.expedia.com/Hotel-Search?destination=La+Mesa%2C+California%2C+United+States+of+America®ionId=8484&latLong=32.76783%2C-117.023086&adults=2&startDate=2026-06-07&d1=2026-06-07&endDate=2026-06-10&d2=2026-06-10&lodging=APART_HOTEL) Condos [](https://www.expedia.com/Hotel-Search?destination=La+Mesa%2C+California%2C+United+States+of+America®ionId=8484&latLong=32.76783%2C-117.023086&adults=2&startDate=2026-06-07&d1=2026-06-07&endDate=2026-06-10&d2=2026-06-10&lodging=CONDO) Apartments [](https://www.expedia.com/Hotel-Search?destination=La+Mesa%2C+California%2C+United+States+of+America®ionId=8484&latLong=32.76783%2C-117.023086&adults=2&startDate=2026-06-07&d1=2026-06-07&endDate=2026-06-10&d2=2026-06-10&lodging=APARTMENT) Cottages [](https://www.expedia.com/Hotel-Search?destination=La+Mesa%2C+California%2C+United+States+of+America®ionId=8484&latLong=32.76783%2C-117.023086&adults=2&startDate=2026-06-07&d1=2026-06-07&endDate=2026-06-10&d2=2026-06-10&lodging=COTTAGE) Villas [](https://www.expedia.com/Hotel-Search?destination=La+Mesa%2C+California%2C+United+States+of+America®ionId=8484&latLong=32.76783%2C-117.023086&adults=2&startDate=2026-06-07&d1=2026-06-07&endDate=2026-06-10&d2=2026-06-10&lodging=VILLA) Cabins [](https://www.expedia.com/Hotel-Search?destination=La+Mesa%2C+California%2C+United+States+of+America®ionId=8484&latLong=32.76783%2C-117.023086&adults=2&startDate=2026-06-07&d1=2026-06-07&endDate=2026-06-10&d2=2026-06-10&lodging=CABIN) Houseboats [](https://www.expedia.com/Hotel-Search?destination=La+Mesa%2C+California%2C+United+States+of+America®ionId=8484&latLong=32.76783%2C-117.023086&adults=2&startDate=2026-06-07&d1=2026-06-07&endDate=2026-06-10&d2=2026-06-10&lodging=HOUSE_BOAT) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FLa-Mesa-Vacation-Rentals.d8484.Travel-Guide-VacationRentals)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FLa-Mesa-Vacation-Rentals.d8484.Travel-Guide-VacationRentals) ## Top La Mesa Hotel Reviews ![The Bristol Hotel San Diego](https://images.trvl-media.com/lodging/1000000/30000/23900/23816/d154e491_y.jpg) ### The Bristol Hotel San Diego 4/10 Poor "The bathroom smelled moldy and had what looked like black mold on the grout. The bed was super comfortable, and gym was a nice size. " [](https://expedia.com/San-Diego-Hotels-The-Bristol-Hotel-San-Diego.h23816.Hotel-Information) ![Bahia Resort Hotel](https://images.trvl-media.com/lodging/1000000/20000/18300/18241/1b98f5a3_y.jpg) ### Bahia Resort Hotel 10/10 Excellent "Clean room, spacious, friendly staff" [](https://expedia.com/San-Diego-Hotels-Bahia-Resort-Hotel.h18241.Hotel-Information) ![Best Western Seven Seas](https://images.trvl-media.com/lodging/1000000/10000/1800/1734/w3837h2556x3y3-8b148daf_y.jpg) ### Best Western Seven Seas 2/10 Terrible "Stinks like damp moldy den. One light had a dead bulb so it was dark in the room. Mattress hurt our backs the next morning. Horrible experience at seven seas." [](https://expedia.com/San-Diego-Hotels-Best-Western-Seven-Seas.h1734.Hotel-Information) ![Hyatt Regency Mission Bay Spa and Marina](https://images.trvl-media.com/lodging/1000000/10000/900/858/543624c5_y.jpg) ### Hyatt Regency Mission Bay Spa and Marina 10/10 Excellent "Great ocean view!" [](https://expedia.com/San-Diego-Hotels-Hyatt-Regency-Mission-Bay-Spa-And-Marina.h858.Hotel-Information) ![Hard Rock Hotel San Diego](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/7e147d0f_y.jpg) ### Hard Rock Hotel San Diego 10/10 Excellent "Great place " [](https://expedia.com/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) ![San Diego Mission Bay Resort](https://images.trvl-media.com/lodging/1000000/30000/25600/25598/b5f2a64d_y.jpg) ### San Diego Mission Bay Resort 6/10 Okay "My stay at this hotel was just average. The hotel itself is pleasant, but nothing extraordinary. Upon arrival, I was charged $400, which included resort fees and parking. While this amount seemed excessive for a three-night stay, I suppose it’s what you get for a resort. The rooms were also ordinary, nothing to write home about. However, the housekeeping was satisfactory, and the pool area was charming. " [](https://expedia.com/San-Diego-Hotels-San-Diego-Mission-Bay-Resort.h25598.Hotel-Information) ![The Dana on Mission Bay](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/8e8c5197_y.jpg) ### The Dana on Mission Bay 10/10 Excellent "All great" [](https://expedia.com/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information) ![Days Inn by Wyndham San Diego Hotel Circle](https://images.trvl-media.com/lodging/1000000/20000/19300/19220/c491024e_y.jpg) ### Days Inn by Wyndham San Diego Hotel Circle 8/10 Good "Clean rooms, comfortable beds and close/centrally located driving distance to all main attractions." [](https://expedia.com/San-Diego-Hotels-Days-Inn-By-Wyndham-San-Diego-Hotel-Circle.h19220.Hotel-Information) ![Bay Club Hotel & Marina](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/4003f7ef_y.jpg) ### Bay Club Hotel & Marina 10/10 Excellent "Recently finished three nights in San Diego and was very pleasantly surprised with our stay at the Bay club. Had never really heard of it, but we come down to San Diego about once a year. Loved the neighborhood, stayed with two adults a 9 and 11 year old. Rooms were clean, well appointed and perfect for our purposes. Loved staying at a smaller hotel, it’s nice to not be at a huge hotel with tons of people. Bar / restaurant was great, ate there a couple times when we didn’t want to leave. Pool and hot tub were perfect, with a great view of the marina. Only one complaint I could think of, was no ice machine. But the people at the restaurant/ bar were always happy to fill our bucket or reusable bottles. But if unit were late at night, or you needed a bunch of ice this might be a bit annoying. Other than that most likely will stay again!" [](https://expedia.com/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information) ## Find out more about La Mesa **Everything you need to know about La Mesa vacation rentals** Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the La Mesa vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on. There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect La Mesa vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. **La Mesa vacation rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in La Mesa. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit La Mesa in high season. Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $102 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals! **How to find incredible deals on La Mesa rentals** At Expedia, we put the best La Mesa vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. To find some top La Mesa rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream La Mesa vacation. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around La Mesa. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. ## Explore a world of travel with Expedia - Trending destinations on Expedia.com - All accommodation types in La Mesa ### Trending destinations on Expedia.com - [Destin Vacation Rentals ](https://www.expedia.com/Destin-Vacation-Rentals.d6906.Travel-Guide-VacationRentals) - [Panama City Vacation Rentals ](https://www.expedia.com/Panama-City-Beach-Vacation-Rentals.d8021.Travel-Guide-VacationRentals) - [Hilton Head Vacation Rentals ](https://www.expedia.com/Hilton-Head-Island-Vacation-Rentals.d601684.Travel-Guide-VacationRentals) - [Gulf Shores Vacation Rentals ](https://www.expedia.com/Gulf-Shores-Vacation-Rentals.d603078.Travel-Guide-VacationRentals) - [Key West Vacation Rentals ](https://www.expedia.com/Key-West-Vacation-Rentals.d1187.Travel-Guide-VacationRentals) - [Gatlinburg Vacation Rentals ](https://www.expedia.com/Gatlinburg-Vacation-Rentals.d7474.Travel-Guide-VacationRentals) - 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[Vacation Homes in La Mesa ](https://expedia.com/La-Mesa-Private-Vacation-Homes.d8484-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Apartments in La Mesa ](https://expedia.com/La-Mesa-Apartments.d8484-aaApartments.Travel-Guide-Accommodation) - [Condo Rentals in La Mesa ](https://expedia.com/La-Mesa-Condos.d8484-aaCondos.Travel-Guide-Accommodation) - [Cottages in La Mesa ](https://expedia.com/La-Mesa-Cottages.d8484-aaCottages.Travel-Guide-Accommodation) - [Villas in La Mesa ](https://expedia.com/La-Mesa-Villas.d8484-aaVillas.Travel-Guide-Accommodation) - [Guest Houses in La Mesa ](https://expedia.com/La-Mesa-Guest-Houses.d8484-aaGuestHouses.Travel-Guide-Accommodation) - [Resorts in La Mesa ](https://expedia.com/La-Mesa-Resorts.d8484-aaResorts.Travel-Guide-Accommodation) - [Aparthotels in La Mesa ](https://expedia.com/La-Mesa-Apart-Hotels.d8484-aaApartHotels.Travel-Guide-Accommodation) - [Motels in La Mesa ](https://expedia.com/La-Mesa-Motels.d8484-aaMotels.Travel-Guide-Accommodation) - [Hostels in La Mesa ](https://expedia.com/La-Mesa-Hostels.d8484-aaHostels.Travel-Guide-Accommodation) - [Cabin Rentals in La Mesa ](https://expedia.com/La-Mesa-Cabins.d8484-aaCabins.Travel-Guide-Accommodation) - [B&B in La Mesa ](https://expedia.com/La-Mesa-Bed-And-Breakfast.d8484-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Farmstay in La Mesa ](https://expedia.com/La-Mesa-Agritourism.d8484-aaAgritourism.Travel-Guide-Accommodation) - [RV Parks in La Mesa ](https://expedia.com/La-Mesa-RV-Parks.d8484-aaRVParks.Travel-Guide-Accommodation) - [Houseboats in La Mesa ](https://expedia.com/La-Mesa-Houseboats.d8484-aaHouseboats.Travel-Guide-Accommodation) - [Inns in La Mesa ](https://expedia.com/La-Mesa-Inns.d8484-aaInns.Travel-Guide-Accommodation) - [Residences in La Mesa ](https://expedia.com/La-Mesa-Residences.d8484-aaResidences.Travel-Guide-Accommodation) - [Castles in La Mesa ](https://expedia.com/La-Mesa-Castles.d8484-aaCastles.Travel-Guide-Accommodation) ## Frequently asked questions ### Are there vacation rentals in La Mesa? ### What are some of the best vacation rentals that La Mesa has to offer? ### How many vacation rentals are there in La Mesa? ### What can I see and do in La Mesa? ### What are vacation rentals like in La Mesa? ### Expedia's Latest Trends Hotels - 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