La Mesa Vacation Rentals

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Our top choices for La Mesa vacation rentals

Vacation Home in Mount Helix

La Mesa New 3BR Oasis with Pool and Games!
10.0 out of 10, Exceptional, (1 review)
"Yes, Excellent workspace."
United States
Stanley H.
$499 nightly
The price is $499
Jan 28 - Jan 29
Total with taxes and fees
La Mesa New 3BR Oasis with Pool and Games!
$303 nightly
The price is $303
Jan 24 - Jan 25
Total with taxes and fees
Mediterranean-inspired 1BR Guesthouse - Full Kitchen, Workspace & Garden
8.4 out of 10, Very Good, (6 reviews)
"We stayed at this beautiful VRBO for our child’s college graduation in San Diego, and it couldn’t have been more perfect. The home was spotless, spacious, and exactly as described—if not better! Every room was thoughtfully appointed, and the beds were incredibly comfortable. The kitchen had everything we needed to cook family meals, and we loved gathering in the common areas to celebrate and relax.The location was ideal—close to the campus and shopping.Our host was responsive, welcoming, and...
United States
Michele G.
$396 nightly
The price is $396
Jan 25 - Jan 26
Total with taxes and fees
SDSU/Downtown <10 Min - GameRoom - Fire Pit - Free Parking - Easy Freeway Access
$352 nightly
The price is $382
Jan 24 - Jan 25
Total with taxes and fees
Spacious 4BR/2BTH King Bed Ranch Style, Prime Area
9.0 out of 10, Wonderful, (2 reviews)
"We love a simple no-nonsense place and this was perfect for us. The host is very responsive and was constantly checking in with us on what else we need to be comfortable to stay here. The area is close a lot of nice restaurants so that was a plus. We would love to stay here next time we visit San Diego."
United States
Darakhshan T.
$183 nightly
The price is $193
Jan 24 - Jan 25
Total with taxes and fees
An elegant, fully furnished guest house for 2-4 guest in San Diego
$1,884 nightly
The price is $1,884
Jan 25 - Jan 26
Total with taxes and fees
Luxury 5BR Villa - Pool, Spa, Movie Theater, Game Room, Bar, & Outdoor Dining
$338 nightly
The price is $368
Jan 25 - Jan 26
Total with taxes and fees
4BR/3Bth King Bed, Big Yard, Prime Area, Ranch

Aparthotel in Downtown San Diego

Sentral Gaslamp Quarter
4.0 star property
9.4 out of 10, Exceptional, (643 reviews)
"Great place to stay "
United States
KELLY
$152 nightly
The price is $176
Jan 25 - Jan 26
Total with taxes and fees
Sentral Gaslamp Quarter
2.5 star property
8.4 out of 10, Very Good, (275 reviews)
"Overall good place."
United States
Isaac
$105 nightly
The price is $119
Jan 25 - Jan 26
Total with taxes and fees
Uptown Inn by Vantaggio - Limited Service Apart-Hotel
4.5 star property
9.6 out of 10, Exceptional, (112 reviews)
"would definitely go back and stay there again "
United States
Kounwick
$178 nightly
The price is $201
Jan 26 - Jan 27
Total with taxes and fees
City24 Hotel Little Italy Mission Hills
7.4 out of 10, Good, (6 reviews)
"It was beautiful and very modern. We loved it and hope to come back again!! "
United States
Ronette B.
$183 nightly
The price is $188
Feb 1 - Feb 2
Total with taxes and fees
Luxury Studio with Lake Views and Spacious Balcony
9.6 out of 10, Exceptional, (54 reviews)
"Second stay and we’ll be back !! Good location, owner easy to work with, clean & tidy !!"
United States
Kevin O.
$194 nightly
The price is $216
Jan 29 - Jan 30
Total with taxes and fees
Cozy Pacific Beach Cottage w/Bikes, Private Yard & Entrance
3.0 star property
8.0 out of 10, Very Good, (1 review)
"The studio was beautiful, clean, and cozy. The only thing that I will say is that the pictures advertised show both the main home and the studio, so it is misleading as to what amenities are available in your own space. Other than that I enjoyed my stay and the owner was very prompt to respond to the few questions that I had."
United States
Fatimah
$273 nightly
The price is $308
Feb 8 - Feb 9
Total with taxes and fees
New Cozy Studio 2 Queen Beds, Kitchen Walk to Water

Condo in Historic Downtown Coronado

Coronado Beach Resort
3.0 star property
9.0 out of 10, Wonderful, (760 reviews)
"Ideal location walkable to many restaurants and the beach. Great spot and lovely staff"
United States
Justine
$219 nightly
The price is $241
Feb 8 - Feb 9
Total with taxes and fees
Coronado Beach Resort
8.6 out of 10, Excellent, (31 reviews)
"Each room had separate climate controls, very nice. The neighborhood was a bit sketchy, but very close to where we needed to go."
United States
Armorblue D.
$212 nightly
The price is $236
Feb 9 - Feb 10
Total with taxes and fees
'Ted' 2-bedroom cozy house in central location! 10 minutes to Balboa!
10.0 out of 10, Exceptional, (3 reviews)
"Very clean and located in beautiful area."
Canada
Rafa P.
$124 nightly
The price is $137
Jan 26 - Jan 27
Total with taxes and fees
Soothing studio with AC in sunny San Diego
9.8 out of 10, Exceptional, (11 reviews)
"Our visit was short but really enjoyed our stay. Definitely will stay here again when traveling with family or friends. Place was clean and comfortable."
United States
Michelle M.
$305 nightly
The price is $339
Feb 2 - Feb 3
Total with taxes and fees
2BR House in Central San Diego, Right Next to SDSU, Free Parking
9.6 out of 10, Exceptional, (4 reviews)
"Lovely place in a lovely part of the world. Highly recommend "
United States
Luke G.
$179 nightly
The price is $199
Jan 25 - Jan 26
Total with taxes and fees
Private Suite In Charming,Historic OB Cottage-Yard/Patio-Blocks To Beaches/Shops

Condo in Del Mar

Wave Crest Resort
3.0 star property
9.2 out of 10, Wonderful, (147 reviews)
"Great location "
United States
Erin
$242 nightly
The price is $269
Feb 2 - Feb 3
Total with taxes and fees
Wave Crest Resort

Apartment in Mount Helix

Cozy Private Studio in El Cajon
8.6 out of 10, Excellent, (20 reviews)
"Close to freeway. Nice and quiet. Good communication "
United States
Rex Tami
$97 nightly
The price is $97
Jan 25 - Jan 26
Total with taxes and fees
Cozy Private Studio in El Cajon
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top La Mesa Hotel Reviews

Find out more about La Mesa

Everything you need to know about La Mesa vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the La Mesa vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect La Mesa vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

La Mesa vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in La Mesa. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit La Mesa in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $119 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on La Mesa rentals

At Expedia, we put the best La Mesa vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top La Mesa rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream La Mesa vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around La Mesa. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Are there vacation rentals in La Mesa?

Yes, you can find vacation rentals in La Mesa near Computer Museum of America, or you can choose a secluded option if you'd like a relaxing place to stay. Visitors like the top-notch restaurants and shops in La Mesa. Leave some time to check out the zoo and entertainment venues during your trip.

What are some of the best vacation rentals that La Mesa has to offer?

3 Story Spanish Style House, Best Location in SD. Views of North Park, With AC: You might want to consider this vacation home rental near La Mesa, which has air-conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings.

How many vacation rentals are there in La Mesa?

With 60 Expedia vacation rentals, you're sure to find just the right place for your La Mesa stay.

What can I see and do in La Mesa?

Explore the area and cultural attractions such as Computer Museum of America, or visit a family-friendly sight such as San Diego Zoo. While in the area, you can also visit popular places like Mission Bay and Petco Park.

What are vacation rentals like in La Mesa?

Vacation rentals are privately owned properties you can book for several days or more in La Mesa. Vacation rentals feature amenities such as WiFi and washers and dryers so you'll have everything you need. If you're concerned about a clean environment, vacation rentals can provide a sense of safety away from shared hotel elevators and busy lobbies while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a traditional hotel, which makes a vacation rental a great choice for families.