Santa Isabel

Travel Guide

A person paddleboarding on a calm sea with wind turbines in the background.
A landscape with multiple wind turbines and agricultural fields.
A landscape with wind turbines and agricultural fields.
Hotel Las Vegas

Hotel Las Vegas

3 out of 5
PR 153, Km 2.9 Santa Isabel
Fully refundable
$77 nightly
The price is $84 total per night from Oct 22 to Oct 23
$84 total
Oct 22 - Oct 23
Total with taxes and fees
Stay at this motel in Santa Isabel. Enjoy 24-hour room service, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (393 reviews)
"Muy bueno"

Reviewed on Oct 14, 2026

Hotel Las Vegas
Hacienda del Sur

Hacienda del Sur

2 out of 5
Carr 545 KM 1.5, Sector Gabia Santa Isabel
$132 nightly
The price is $143 total per night from Oct 18 to Oct 19
$143 total
Oct 18 - Oct 19
Total with taxes and fees
Stay at this hotel in Santa Isabel. Enjoy free WiFi, free parking, and a garden. Popular attractions Carribbean Cinemas Santa Isabel and Coamo Springs are located ...
Hacienda del Sur
3BR Puerto Rico Villa w Pool | Aqua Bella 1

3BR Puerto Rico Villa w Pool | Aqua Bella 1

Santa Isabel PR
Stay at this vacation home in Santa Isabel. Enjoy free WiFi, private pools, and a garden. Popular attraction Carribbean Cinemas Santa Isabel is located ...
9.8/10 Exceptional! (9 reviews)
"Amazing"

Reviewed on Sep 23, 2026

3BR Puerto Rico Villa w Pool | Aqua Bella 1
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
3BR Puerto Rico Villa w Pool | Aqua Bella 1

3BR Puerto Rico Villa w Pool | Aqua Bella 1

Santa Isabel PR
Stay at this vacation home in Santa Isabel. Enjoy free WiFi, private pools, and a garden. Popular attraction Carribbean Cinemas Santa Isabel is located ...
9.8/10 Exceptional! (9 reviews)
"Amazing"

Reviewed on Sep 23, 2026

3BR Puerto Rico Villa w Pool | Aqua Bella 1
Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep

Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep

Santa Isabel
Book a stay at this beach vacation home in Santa Isabel. Enjoy free WiFi, a beach locale, and laundry facilities. Popular attractions Playa La Ochenta and Carribbean ...
8.8/10 Excellent! (50 reviews)
"Nice house, lots of room, beautiful view. Area (stairs ) to get down to water needs repairVery accommodating for whole family, lots of local restaurants nearby, close to shopping, would recommend this place & would stay here again"

Reviewed on Aug 23, 2026

Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep
Modern Cozy Home in Puerto Rican Paradise

Modern Cozy Home in Puerto Rican Paradise

Santa Isabel
Stay at this vacation home in Santa Isabel. Enjoy free WiFi, an in-room coffeemaker, and air conditioning. Popular attractions Carribbean Cinemas Santa Isabel ...
9.2/10 Wonderful! (17 reviews)
"Yes thank you letting stay in this place. Very quiet for most of the time and I am new to this area even after growing up here. Everything was great however the house needs some checking because there are some ants and few cockroaches around the house. Also check the shower drain. Besides that every ..."

Reviewed on Jul 5, 2026

Modern Cozy Home in Puerto Rican Paradise
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Santa Isabel attractions

Things to do

Frequently asked questions

Is Santa Isabel worth visiting?
Santa Isabel is worth visiting for its local culinary experiences, where travelers can savor a variety of Italian and Latin American dishes. The destination also offers entertainment opportunities, such as enjoying a film at Caribbean Cinemas Santa Isabel.
When is the best time to visit Santa Isabel?
The best time to visit Santa Isabel is from November through March, when the climate is typically most pleasant. For travelers seeking fewer crowds and potentially better value, the warmer months of June through September are a good option.
What is Santa Isabel known for?
Santa Isabel is known for Caribbean Cinemas Santa Isabel, a popular local entertainment venue. This city in Puerto Rico also offers travelers a chance to explore its Italian food culture, with various dining options available to enjoy.
What is a good itinerary length for Santa Isabel?
An extended stay of three to four days allows more time to relax and explore the local Italian, Latin American, or seafood dining options.
What cuisines can you find in Santa Isabel?
In Santa Isabel, travelers can find South American cuisine, with dishes like empanadas, ceviche, and churrasco. You can also enjoy a variety of other options, including Italian, seafood, Asian, and North American dishes. Travelers can also find local coffee shops.
Can I book a refundable hotel in Santa Isabel?
Yes, Expedia offers many flexible booking options, and you can look for refundable hotels in Santa Isabel by entering your dates and using the refundable or fully refundable filter. Always check the hotel's cancellation policy before you book, since terms can vary by hotel, and visit Expedia help center for further details.
Why book a trip to Santa Isabel with Expedia?
Expedia makes it easier to plan your Santa Isabel trip with travel tools, flexible search options, and bookable trip components all in one place. You can organize your plans in one account and use Expedia to help build a trip that fits your budget and travel style. Find out more about how by visiting Expedia's Trip Planner page.
Should I stay in a hotel or vacation rental in Santa Isabel?
The best choice depends on your travel style. Hotels in Santa Isabel can be a good fit for convenience, on-site amenities, and shorter stays, while vacation rentals may offer more space, privacy, and home-style amenities for longer trips, families, or groups. With Expedia, you can compare both options side by side, read traveler reviews, and filter by amenities to find the right fit for your trip.
How can I manage my Santa Isabel trip on Expedia?
Once you've booked your Santa Isabel trip, you can manage it through your Expedia account or the Expedia app. You can view your itinerary, access booking details, make eligible changes, and check for updates in My Trips. The Expedia app can also help you stay organized while you travel.
What if I need help during my Santa Isabel trip?
Expedia offers customer support before, during, and after your Santa Isabel trip. If your plans change or something unexpected happens, you can review your booking in My Trips and use Expedia help center channels for help with eligible changes, cancellations, or travel issues.
How can Expedia help me plan my first trip to Santa Isabel?
If it's your first trip to Santa Isabel, Expedia can help you plan by bringing together stays, flights, activities, traveler reviews, and trip-planning tools in one place. With Expedia's Trip Planner you can compare options, read reviews from other travelers, and build an itinerary that matches your interests and budget.
How can I save on my Santa Isabel hotel booking with Expedia?
Join One Key™ for free to unlock instant discounts with Member Prices on select hotels. You can also earn and use OneKeyCash™* on eligible bookings on Expedia. Booking in advance is usually another great way to save on your Santa Isabel hotel.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.

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