$314 Cheap Flights from Hermosillo (HMO) to Des Moines (DSM)

View $314 flight on Mon, Jan 12, 2026Opens in a new window

Popular airlines from Hermosillo, Sonora (HMO-General Ignacio Pesqueira Garcia Intl.) to Des Moines International Airport (DSM)

Cheap Flights from Hermosillo to Des Moines (HMO-DSM)

Prices were available within the past 7 days and start at $314 for one-way flights and $561 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Mon, Dec 22 - Mon, Jan 12
HMO
Hermosillo
DSM
Des Moines
$561 Roundtrip, found 6 days ago
$561
Roundtrip
found 6 days ago
Select American Airlines flight, departing Mon, Dec 22 from Hermosillo to Des Moines, returning Mon, Jan 12, priced at $561 found 6 days ago
American Airlines
Mon, Dec 22 - Mon, Jan 12
HMO
Hermosillo
DSM
Des Moines
$566 Roundtrip, found 6 days ago
$566
Roundtrip
found 6 days ago
Select American Airlines flight, departing Mon, Dec 22 from Hermosillo to Des Moines, returning Mon, Jan 12, priced at $566 found 6 days ago
American Airlines
Mon, Dec 22 - Mon, Jan 12
HMO
Hermosillo
DSM
Des Moines
$582 Roundtrip, found 6 days ago
$582
Roundtrip
found 6 days ago
Select American Airlines flight, departing Mon, Dec 22 from Hermosillo to Des Moines, returning Mon, Jan 12, priced at $582 found 6 days ago
American Airlines
Mon, Dec 22 - Mon, Jan 12
HMO
Hermosillo
DSM
Des Moines
$587 Roundtrip, found 6 days ago
$587
Roundtrip
found 6 days ago
Select American Airlines flight, departing Mon, Dec 22 from Hermosillo to Des Moines, returning Mon, Jan 12, priced at $587 found 6 days ago
American Airlines
Mon, Dec 22 - Mon, Jan 12
HMO
Hermosillo
DSM
Des Moines
$608 Roundtrip, found 6 days ago
$608
Roundtrip
found 6 days ago
Select American Airlines flight, departing Mon, Dec 22 from Hermosillo to Des Moines, returning Mon, Jan 12, priced at $608 found 6 days ago
American Airlines
Mon, Dec 22 - Mon, Jan 12
HMO
Hermosillo
DSM
Des Moines
$615 Roundtrip, found 6 days ago
$615
Roundtrip
found 6 days ago
Select American Airlines flight, departing Mon, Dec 22 from Hermosillo to Des Moines, returning Mon, Jan 12, priced at $615 found 6 days ago
American Airlines
Mon, Dec 22 - Mon, Jan 12
HMO
Hermosillo
DSM
Des Moines
$625 Roundtrip, found 6 days ago
$625
Roundtrip
found 6 days ago
Select American Airlines flight, departing Mon, Dec 22 from Hermosillo to Des Moines, returning Mon, Jan 12, priced at $625 found 6 days ago
American Airlines
Mon, Dec 22 - Mon, Jan 12
HMO
Hermosillo
DSM
Des Moines
$630 Roundtrip, found 6 days ago
$630
Roundtrip
found 6 days ago
Select American Airlines flight, departing Mon, Dec 22 from Hermosillo to Des Moines, returning Mon, Jan 12, priced at $630 found 6 days ago
American Airlines
Mon, Dec 22 - Mon, Jan 12
HMO
Hermosillo
DSM
Des Moines
$646 Roundtrip, found 6 days ago
$646
Roundtrip
found 6 days ago
Select American Airlines flight, departing Mon, Dec 22 from Hermosillo to Des Moines, returning Mon, Jan 12, priced at $646 found 6 days ago
Delta
Mon, Dec 22 - Mon, Jan 12
HMO
Hermosillo
DSM
Des Moines
$1,718 Roundtrip, found 6 days ago
$1,718
Roundtrip
found 6 days ago
Select Delta flight, departing Mon, Dec 22 from Hermosillo to Des Moines, returning Mon, Jan 12, priced at $1,718 found 6 days ago
Flights from Hermosillo (HMO) to Des Moines (DSM)
Origin airport
General Ignacio Pesqueira Garcia Intl.
Destination airport
Des Moines Intl.
Roundtrip price
$560
Distance
1299 mi

Hermosillo to Des Moines Flights

The cheapest times to fly from Hermosillo to Des Moines

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Hermosillo to Des Moines are during the month of December. You can find some of the cheapest flights from Hermosillo to Des Moines with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Hermosillo to Des Moines

Sunday is one of the best days to book for cheap flights from Hermosillo to Des Moines: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Hermosillo to Des Moines

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Hermosillo to Des Moines in 2025. You can also book with separate airlines for your outbound and return journeys, from $314 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Hermosillo to Des Moines flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Hermosillo to Des Moines airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from General Ignacio Pesqueira Garcia Intl. Airport (HMO) to Des Moines Intl. Airport (DSM) cost?
Grab a cheap one-way flight from $314 or cheap return flight from $561 from General Ignacio Pesqueira Garcia Intl. Airport (HMO) to Des Moines Intl. Airport (DSM) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from General Ignacio Pesqueira Garcia Intl. Airport (HMO) to Des Moines Intl. Airport (DSM)?
The cheapest month to fly from HMO to DSM is December, when demand is low. Off-peak months are generally when airlines offer lower prices between these airports.
What is the cheapest airline that flies from General Ignacio Pesqueira Garcia Intl. Airport (HMO) to Des Moines Intl. Airport (DSM)?
Use the filters on Expedia to compare airlines and find the most affordable carrier that'll fly you from HMO to DSM. Then, sort your results by "Price (lowest to highest)" to snap up a good deal.
How many flights per day from General Ignacio Pesqueira Garcia Intl. Airport (HMO) to Des Moines Intl. Airport (DSM)?
You'll have to take a flight with a layover if you're traveling from General Ignacio Pesqueira Garcia Intl. Airport (HMO) to Des Moines Intl. Airport (DSM). Direct flights don't operate daily on this route. However, just filter your search to include one or more stops to discover an option that works for you.
What day of the week has the most flights from HMO to DSM?
You'll generally find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from General Ignacio Pesqueira Garcia Intl. Airport (HMO) to Des Moines Intl. Airport (DSM)?
To land at Des Moines Intl. Airport (DSM) without delays, select a flight that leaves General Ignacio Pesqueira Garcia Intl. Airport (HMO) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from General Ignacio Pesqueira Garcia Intl. Airport (HMO) to Des Moines Intl. Airport (DSM) last-minute?
Last-minute fares from HMO to DSM are typically more expensive. For the lowest prices, start looking for flights as soon as possible. That being said, if your travel plans are flexible, you may land a cheap ticket right before your trip.
Is it cheaper to book a HMO to DSM flight and hotel package?
Compared with arranging flights and hotels separately, booking a HMO to DSM flight and hotel package with Expedia could lead to significant savings. What's more, having it all in one place will take the stress out of planning your trip. Simply pick your flights and choose from our extensive range of hotels, then customize your trip with extras like tours, activities and car rentals.
Can I cancel or change the date of my flight from General Ignacio Pesqueira Garcia Intl. Airport (HMO) to Des Moines Intl. Airport (DSM)?
If you reserved your HMO to DSM flight within the last 24 hours, you may be able to cancel or modify it without any fees. Depending on the airline and the type of ticket you purchased, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal for further details.

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*Available to One Key members.