$119 Cheap Flights from San Antonio (SAT) to Des Moines (DSM)

View $119 flight on Thu, Sep 11, 2025Opens in a new window

Popular airlines from San Antonio International Airport (SAT) to Des Moines International Airport (DSM)

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Cheap Flights from San Antonio to Des Moines (SAT-DSM)

Prices were available within the past 7 days and start at $119 for one-way flights and $225 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Sat, Sep 13 - Fri, Sep 26
SAT
San Antonio
DSM
Des Moines
$225 Roundtrip, found 6 days ago
$225
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Sat, Sep 13 from San Antonio to Des Moines, returning Fri, Sep 26, priced at $225 found 6 days ago
Frontier Airlines
Sat, Sep 20 - Fri, Sep 26
SAT
San Antonio
DSM
Des Moines
$235 Roundtrip, found 6 days ago
$235
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Sat, Sep 20 from San Antonio to Des Moines, returning Fri, Sep 26, priced at $235 found 6 days ago
Southwest Airlines
Tue, Sep 16 - Tue, Sep 23
SAT
San Antonio
DSM
Des Moines
$237 Roundtrip, found 4 hours ago
$237
Roundtrip
found 4 hours ago
Select Southwest Airlines flight, departing Tue, Sep 16 from San Antonio to Des Moines, returning Tue, Sep 23, priced at $237 found 4 hours ago
United
Mon, Sep 15 - Thu, Sep 25
SAT
San Antonio
DSM
Des Moines
$237 Roundtrip, found 2 hours ago
$237
Roundtrip
found 2 hours ago
Select United flight, departing Mon, Sep 15 from San Antonio to Des Moines, returning Thu, Sep 25, priced at $237 found 2 hours ago
Delta
Thu, Sep 11 - Tue, Sep 16
SAT
San Antonio
DSM
Des Moines
$237 Roundtrip, just found
$237
Roundtrip
just found
Select Delta flight, departing Thu, Sep 11 from San Antonio to Des Moines, returning Tue, Sep 16, priced at $237 just found
American Airlines
Thu, Sep 11 - Mon, Sep 15
SAT
San Antonio
DSM
Des Moines
$237 Roundtrip, just found
$237
Roundtrip
just found
Select American Airlines flight, departing Thu, Sep 11 from San Antonio to Des Moines, returning Mon, Sep 15, priced at $237 just found
Southwest Airlines
Wed, Aug 27 - Tue, Sep 2
SAT
San Antonio
DSM
Des Moines
$238 Roundtrip, found 4 hours ago
$238
Roundtrip
found 4 hours ago
Select Southwest Airlines flight, departing Wed, Aug 27 from San Antonio to Des Moines, returning Tue, Sep 2, priced at $238 found 4 hours ago
American Airlines
Wed, Aug 27 - Tue, Sep 2
SAT
San Antonio
DSM
Des Moines
$239 Roundtrip, found 4 hours ago
$239
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Wed, Aug 27 from San Antonio to Des Moines, returning Tue, Sep 2, priced at $239 found 4 hours ago
Southwest Airlines
Tue, Sep 16 - Tue, Sep 23
SAT
San Antonio
DSM
Des Moines
$242 Roundtrip, found 4 hours ago
$242
Roundtrip
found 4 hours ago
Select Southwest Airlines flight, departing Tue, Sep 16 from San Antonio to Des Moines, returning Tue, Sep 23, priced at $242 found 4 hours ago
Southwest Airlines
Wed, Aug 27 - Tue, Sep 2
SAT
San Antonio
DSM
Des Moines
$243 Roundtrip, found 4 hours ago
$243
Roundtrip
found 4 hours ago
Select Southwest Airlines flight, departing Wed, Aug 27 from San Antonio to Des Moines, returning Tue, Sep 2, priced at $243 found 4 hours ago

Find the cheapest month to fly from San Antonio (SAT) to Des Moines (DSM)

September is typically the cheapest month to fly

From $150 - $562 per traveler.

Graph displaying average flight prices per month

Flights from San Antonio (SAT) to Des Moines (DSM)
Origin airport
San Antonio Intl.
Destination airport
Des Moines Intl.
Airlines serving
American Airlines, Delta, Frontier Airlines, Southwest Airlines, United
Roundtrip price
$225
Distance
872 mi

San Antonio to Des Moines Flights

The cheapest times to fly from San Antonio to Des Moines

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from San Antonio to Des Moines are during the month of September. You can find some of the cheapest flights from San Antonio to Des Moines with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from San Antonio to Des Moines

Sunday is one of the best days to book for cheap flights from San Antonio to Des Moines: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from San Antonio to Des Moines

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from San Antonio to Des Moines in 2025. You can also book with separate airlines for your outbound and return journeys, from $119 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap San Antonio to Des Moines flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your San Antonio to Des Moines airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from San Antonio Intl. Airport (SAT) to Des Moines Intl. Airport (DSM) cost?
Discover the latest flight deals from SAT to DSM by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from SAT to DSM?
The cheapest flights from SAT to DSM are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from SAT to DSM?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from SAT to DSM. Sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from San Antonio Intl. Airport (SAT) to Des Moines Intl. Airport (DSM)?
There aren't any daily direct flights from San Antonio Intl. Airport (SAT) to Des Moines Intl. Airport (DSM). But you can choose flights with layovers. Filter your search on Expedia to include one or two stops, and you'll be on your way in no time at all.
What day of the week has the most flights from SAT to DSM?
Usually you'll find the most flight options available on a Friday. Tuesdays tend to be the quietest.* However, this can change based on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from San Antonio Intl. Airport (SAT) to Des Moines Intl. Airport (DSM)?
To land at Des Moines Intl. Airport (DSM) on time, opt for a flight that takes off from San Antonio Intl. Airport (SAT) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from San Antonio Intl. Airport (SAT) to Des Moines Intl. Airport (DSM) last-minute?
Booking your ticket from SAT to DSM just before your journey is generally more expensive. However, if you're flexible with your departure dates and times, you could snag a cheap last-minute fare.
Is it cheaper to book a SAT to DSM flight and hotel package?
You can save money by booking a SAT to DSM flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage everything in one place. After selecting your preferred flights and accommodations, consider other add-ons like activities, car rentals and tours.
Can I cancel or change the date of my flight from San Antonio Intl. Airport (SAT) to Des Moines Intl. Airport (DSM)?
In most instances, you're able to cancel or reschedule your SAT to DSM flight. However, additional charges may apply, especially if you booked over 24 hours ago. Check your itinerary for the airline's fees and policies on flight changes, or if you want more details, head to our Customer Service portal.

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*Available to One Key members.